The network for 'metanephric ascending thin limb development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

metanephric ascending thin limb development

The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.

Name Description Probability Func Analog Organism
Nanog Nanog homeobox 0.992
Otx2 orthodenticle homolog 2 (Drosophila) 0.925
Pax2 paired box gene 2 0.905
Sox2 SRY-box containing gene 2 0.882
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.746
Pkd1 polycystic kidney disease 1 homolog 0.737
Pax6 paired box gene 6 0.692
Pax3 paired box gene 3 0.608
Invs inversin 0.572
Gli3 GLI-Kruppel family member GLI3 0.547
Hmx3 H6 homeobox 3 0.508
Sall4 sal-like 4 (Drosophila) 0.489
Bicc1 bicaudal C homolog 1 (Drosophila) 0.410
Pitx2 paired-like homeodomain transcription factor 2 0.389
Sall3 sal-like 3 (Drosophila) 0.388
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.372
Fgfr2 fibroblast growth factor receptor 2 0.372
Zic3 zinc finger protein of the cerebellum 3 0.357
Chd7 chromodomain helicase DNA binding protein 7 0.348
Vangl2 vang-like 2 (van gogh, Drosophila) 0.335
Foxg1 forkhead box G1 0.315
Atoh7 atonal homolog 7 (Drosophila) 0.311
Fgf8 fibroblast growth factor 8 0.298
Ush1g Usher syndrome 1G homolog (human) 0.278
Slc26a4 solute carrier family 26, member 4 0.261
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.246
Jag1 jagged 1 0.241
Bcl2 B-cell leukemia/lymphoma 2 0.219
Pax8 paired box gene 8 0.200
Pou3f3 POU domain, class 3, transcription factor 3 0.199
Cdh23 cadherin 23 (otocadherin) 0.198
Fgfr1 fibroblast growth factor receptor 1 0.190
Eya1 eyes absent 1 homolog (Drosophila) 0.179
Lhx1 LIM homeobox protein 1 0.179
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.177
Mks1 Meckel syndrome, type 1 0.177
Foxc1 forkhead box C1 0.172
Nodal nodal 0.169
Zic2 zinc finger protein of the cerebellum 2 0.166
Pde6b phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide 0.162
Lmx1a LIM homeobox transcription factor 1 alpha 0.161
Foxh1 forkhead box H1 0.158
Atoh1 atonal homolog 1 (Drosophila) 0.152
Pkd2 polycystic kidney disease 2 0.144
Insm1 insulinoma-associated 1 0.143
Srrm4 serine/arginine repetitive matrix 4 0.143
Mll1 myeloid/lymphoid or mixed-lineage leukemia 1 0.138
Isl1 ISL1 transcription factor, LIM/homeodomain 0.137
Neurod1 neurogenic differentiation 1 0.119
Grxcr1 glutaredoxin, cysteine rich 1 0.117
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.116
Bdnf brain derived neurotrophic factor 0.114
Bmp4 bone morphogenetic protein 4 0.114
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.113
Sall1 sal-like 1 (Drosophila) 0.111
Lhx3 LIM homeobox protein 3 0.109
Gbx2 gastrulation brain homeobox 2 0.109
Esrrb estrogen related receptor, beta 0.108
Tcfcp2l1 transcription factor CP2-like 1 0.104
Tmc1 transmembrane channel-like gene family 1 0.104
Sox11 SRY-box containing gene 11 0.103
Hes5 hairy and enhancer of split 5 (Drosophila) 0.101
Lmx1b LIM homeobox transcription factor 1 beta 0.101
Fgf3 fibroblast growth factor 3 0.098
Tbx10 T-box 10 0.097
T brachyury 0.094
Slc12a1 solute carrier family 12, member 1 0.092
Meox2 mesenchyme homeobox 2 0.090
S1pr2 sphingosine-1-phosphate receptor 2 0.090
Dlx1 distal-less homeobox 1 0.089
Megf8 multiple EGF-like-domains 8 0.087
Sox1 SRY-box containing gene 1 0.087
Tlx3 T-cell leukemia, homeobox 3 0.086
Shh sonic hedgehog 0.086
Emx1 empty spiracles homolog 1 (Drosophila) 0.083
Uncx UNC homeobox 0.073
Foxb1 forkhead box B1 0.072
Otx1 orthodenticle homolog 1 (Drosophila) 0.070
Pou3f2 POU domain, class 3, transcription factor 2 0.069
Hmx1 H6 homeobox 1 0.065
Pcdh15 protocadherin 15 0.064
Sox3 SRY-box containing gene 3 0.063
Elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.062
Cys1 cystin 1 0.061
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.060
Fgf15 fibroblast growth factor 15 0.060
Six3 sine oculis-related homeobox 3 homolog (Drosophila) 0.058
Tcfap2a transcription factor AP-2, alpha 0.058
Slc5a2 solute carrier family 5 (sodium/glucose cotransporter), member 2 0.057
Lhx5 LIM homeobox protein 5 0.057
Oprm1 opioid receptor, mu 1 0.055
Cdk5r2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.054
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.053
Tgfb2 transforming growth factor, beta 2 0.052
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.052
Wnt1 wingless-related MMTV integration site 1 0.052
Vax1 ventral anterior homeobox containing gene 1 0.050
Gsx1 GS homeobox 1 0.049
Pou4f3 POU domain, class 4, transcription factor 3 0.049
Six6 sine oculis-related homeobox 6 homolog (Drosophila) 0.048
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.625
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.014
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism