The network for 'asymmetric neuroblast division' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

asymmetric neuroblast division

The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.

Mus musculus
Name Description Probability Func Analog Organism
Ntf3 neurotrophin 3 0.997
Shh sonic hedgehog 0.996
Gli3 GLI-Kruppel family member GLI3 0.996
Bdnf brain derived neurotrophic factor 0.991
Gli2 GLI-Kruppel family member GLI2 0.990
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.990
Rac1 RAS-related C3 botulinum substrate 1 0.989
Chrd chordin 0.982
Pax2 paired box gene 2 0.975
Ctnnb1 catenin (cadherin associated protein), beta 1 0.971
Ppp2r1a protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform 0.930
Tbx10 T-box 10 0.927
Hoxa1 homeobox A1 0.917
Fgfr2 fibroblast growth factor receptor 2 0.909
Efnb2 ephrin B2 0.883
Twist2 twist homolog 2 (Drosophila) 0.881
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.857
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.853
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.843
Fgfr3 fibroblast growth factor receptor 3 0.830
Zfpm2 zinc finger protein, multitype 2 0.828
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.778
Esr1 estrogen receptor 1 (alpha) 0.774
Sox2 SRY-box containing gene 2 0.773
Isl1 ISL1 transcription factor, LIM/homeodomain 0.752
Fgf9 fibroblast growth factor 9 0.747
Kitl kit ligand 0.719
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.711
Pou4f3 POU domain, class 4, transcription factor 3 0.705
Vangl2 vang-like 2 (van gogh, Drosophila) 0.688
Gal galanin 0.687
Bmpr1a bone morphogenetic protein receptor, type 1A 0.684
Foxc1 forkhead box C1 0.666
Jag1 jagged 1 0.660
Eya1 eyes absent 1 homolog (Drosophila) 0.657
Nr2f1 nuclear receptor subfamily 2, group F, member 1 0.656
Sox9 SRY-box containing gene 9 0.653
Zeb1 zinc finger E-box binding homeobox 1 0.647
Fgf8 fibroblast growth factor 8 0.635
Wnt5a wingless-related MMTV integration site 5A 0.616
Prrx1 paired related homeobox 1 0.615
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.609
Hoxd13 homeobox D13 0.606
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.590
Hand2 heart and neural crest derivatives expressed transcript 2 0.586
Cdk1 cyclin-dependent kinase 1 0.582
Ccnb2 cyclin B2 0.577
Ccnb1 cyclin B1 0.560
Emx1 empty spiracles homolog 1 (Drosophila) 0.556
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 0.554
Msx2 homeobox, msh-like 2 0.552
Cdk2 cyclin-dependent kinase 2 0.550
Otx2 orthodenticle homolog 2 (Drosophila) 0.541
Cfl1 cofilin 1, non-muscle 0.533
Hoxd11 homeobox D11 0.492
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.492
Tcf21 transcription factor 21 0.491
Tbx3 T-box 3 0.485
Rpgrip1l Rpgrip1-like 0.482
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.466
Syt9 synaptotagmin IX 0.448
Foxg1 forkhead box G1 0.445
Trp63 transformation related protein 63 0.438
Prkcz protein kinase C, zeta 0.437
Pthlh parathyroid hormone-like peptide 0.436
Arhgap1 Rho GTPase activating protein 1 0.429
Fgf14 fibroblast growth factor 14 0.428
Ptk7 PTK7 protein tyrosine kinase 7 0.418
Dnajb5 DnaJ (Hsp40) homolog, subfamily B, member 5 0.409
Smad3 MAD homolog 3 (Drosophila) 0.407
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.402
Wdr1 WD repeat domain 1 0.384
Akt1 thymoma viral proto-oncogene 1 0.381
Bmp5 bone morphogenetic protein 5 0.378
Ret ret proto-oncogene 0.363
Hdac7 histone deacetylase 7 0.361
Fgfr1 fibroblast growth factor receptor 1 0.361
Tbx15 T-box 15 0.351
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.340
Capzb capping protein (actin filament) muscle Z-line, beta 0.334
Meox2 mesenchyme homeobox 2 0.332
Nog noggin 0.329
Ephb2 Eph receptor B2 0.328
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.325
Shc3 src homology 2 domain-containing transforming protein C3 0.319
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.316
Sult4a1 sulfotransferase family 4A, member 1 0.313
Tgfb2 transforming growth factor, beta 2 0.312
Gata4 GATA binding protein 4 0.311
Col2a1 collagen, type II, alpha 1 0.305
Gli1 GLI-Kruppel family member GLI1 0.301
Plcg1 phospholipase C, gamma 1 0.297
Pten phosphatase and tensin homolog 0.295
Fbn2 fibrillin 2 0.292
Chd7 chromodomain helicase DNA binding protein 7 0.292
Pax3 paired box gene 3 0.290
Ahr aryl-hydrocarbon receptor 0.284
Gbx2 gastrulation brain homeobox 2 0.283
Rasgrp1 RAS guanyl releasing protein 1 0.274
Cdk5r1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.272
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.658
dcap-2 Protein DCAP-2 0.582
par-1 Protein PAR-1 0.173
inx-3 Protein INX-3 0.161
cam-1 Protein CAM-1 0.134
patr-1 Protein PATR-1 0.131
lag-1 Protein LAG-1 0.117
tax-6 Protein TAX-6 0.111
K10C3.4 Protein K10C3.4 0.107
sem-5 Protein SEM-5 0.105
T26C12.1 Protein T26C12.1 0.103
sel-10 Protein SEL-10 0.097
skpt-1 Protein SKPT-1 0.086
cnt-2 Protein CNT-2 0.069
sel-12 Protein SEL-12 0.048
bath-43 Protein BATH-43 0.046
mes-4 Protein MES-4 0.043
F39B2.1 Protein F39B2.1 0.041
dhhc-1 Protein DHHC-1 0.039
unc-94 Protein UNC-94 0.037
pig-1 Protein PIG-1 0.035
cit-1.1 Protein CIT-1.1 0.031
anc-1 Protein ANC-1 0.030
ZK507.6 Protein ZK507.6 0.028
egl-30 Protein EGL-30 0.027
sun-1 Protein SUN-1 0.027
CELE_Y39G8B.2 Protein Y39G8B.2 0.026
C05D11.7 Protein C05D11.7 0.026
dcp-66 Protein DCP-66 0.026
let-92 Protein LET-92 0.024
F10B5.2 Protein F10B5.2 0.024
sur-2 Protein SUR-2 0.024
tbc-3 Protein TBC-3 0.024
pptr-2 Protein PPTR-2 0.023
pkg-1 Protein PKG-1 0.023
T12B3.4 Protein T12B3.4 0.023
tat-1 Protein TAT-1 0.021
Y119C1A.1 Protein Y119C1A.1 0.021
nhr-6 Protein NHR-6 0.020
ztf-8 Protein ZTF-8 0.019
gei-4 Protein GEI-4 0.019
T28D9.4 Protein T28D9.4 0.018
egl-18 Protein EGL-18 0.017
ash-2 Protein ASH-2 0.017
sex-1 Protein SEX-1 0.017
F16A11.1 Protein F16A11.1 0.017
pct-1 Protein PCT-1 0.016
daf-5 Protein DAF-5 0.016
fzr-1 Protein FZR-1 0.016
rad-51 Protein RAD-51 0.016
F52D10.2 Protein F52D10.2 0.015
gpb-1 Protein GPB-1 0.015
H14A12.3 Protein H14A12.3 0.014
tpa-1 Protein TPA-1 0.014
Y59E9AL.4 Protein Y59E9AL.4 0.014
cap-1 Protein CAP-1 0.014
unc-32 Protein UNC-32 0.014
hlh-30 Protein HLH-30 0.014
gla-3 Protein GLA-3 0.014
unc-9 Protein UNC-9 0.013
paa-1 Protein PAA-1 0.013
hbl-1 Protein HBL-1 0.013
CELE_C25A1.5 Protein C25A1.5 0.012
T15B7.1 Protein T15B7.1 0.012
sup-17 Protein SUP-17 0.012
F22D3.2 Protein F22D3.2 0.012
let-502 Protein LET-502 0.012
rab-11.1 Protein RAB-11.1 0.011
ima-3 Protein IMA-3 0.011
dpy-27 Protein DPY-27 0.011
aph-2 Protein APH-2 0.011
gadr-6 Protein GADR-6 0.011
gsp-1 Protein GSP-1 0.011
dnj-5 Protein DNJ-5 0.011
F12F6.1 Protein F12F6.1 0.011
B0024.11 Protein B0024.11 0.011
CELE_C10C6.6 Protein C10C6.6 0.011
nhl-3 Protein NHL-3 0.011
pro-2 Protein PRO-2 0.011
par-4 Protein PAR-4 0.011
C41D11.4 Protein C41D11.4 0.010
ddx-19 Protein DDX-19 0.010
CELE_F02E9.10 Protein F02E9.10 0.010
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
numb CG3779 gene product from transcript CG3779-RB 1.000
Ggamma1 G protein gamma 1 0.999
G-ialpha65A G protein alphai subunit 65A 0.999
G-oalpha47A G protein oalpha 47A 0.999
stg string 0.996
Rab5 Rab-protein 5 0.984
tws twins 0.969
Sas-4 CG10061 gene product from transcript CG10061-RA 0.929
SoxN SoxNeuro 0.925
CtBP C-terminal Binding Protein 0.906
SAK Sak kinase 0.876
sas-6 spindle assembly abnormal 6 0.868
emc extra macrochaetae 0.830
ttk tramtrack 0.818
drk downstream of receptor kinase 0.803
raps rapsynoid 0.755
insc inscuteable 0.732
wdb widerborst 0.721
neur neuralized 0.716
dap dacapo 0.681
shg shotgun 0.661
flfl falafel 0.646
CG5690 CG5690 gene product from transcript CG5690-RA 0.640
Cep135 CG17081 gene product from transcript CG17081-RB 0.626
neb nebbish 0.611
Rac1 CG2248 gene product from transcript CG2248-RA 0.587
CkIalpha Casein kinase Ialpha 0.575
Poc1 Proteome of centrioles 1 0.573
CG15436 CG15436 gene product from transcript CG15436-RA 0.557
CG6954 CG6954 gene product from transcript CG6954-RB 0.545
CG10267 CG10267 gene product from transcript CG10267-RB 0.541
bam bag of marbles 0.509
Grip71 CG10346 gene product from transcript CG10346-RA 0.479
loco locomotion defects 0.444
Cp110 CG14617 gene product from transcript CG14617-RB 0.441
Gbeta13F G protein beta-subunit 13F 0.433
Adf1 Adh transcription factor 1 0.420
ana3 anastral spindle 3 0.411
sle slender lobes 0.388
pan pangolin 0.371
mira miranda 0.357
mts microtubule star 0.351
stumps CG31317 gene product from transcript CG31317-RC 0.327
par-6 CG5884 gene product from transcript CG5884-RA 0.310
sgg shaggy 0.299
lkb1 CG9374 gene product from transcript CG9374-RJ 0.296
Ephrin CG1862 gene product from transcript CG1862-RA 0.292
rod rough deal 0.287
cdi center divider 0.282
Pkn Protein kinase related to protein kinase N 0.253
Shc SHC-adaptor protein 0.249
ana2 anastral spindle 2 0.248
pbl pebble 0.245
Galpha49B G protein alpha49B 0.236
Gem2 Gemin2 0.230
Cdc42 CG12530 gene product from transcript CG12530-RA 0.230
nct nicastrin 0.219
baz bazooka 0.212
prod proliferation disrupter 0.208
BicD Bicaudal D 0.208
sna snail 0.184
Invadolysin CG3953 gene product from transcript CG3953-RA 0.183
norpA no receptor potential A 0.163
PPP4R2r Protein phosphatase 4 regulatory subunit 2-related protein 0.160
Tre1 trapped in endoderm-1 0.156
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.150
Orc6 Origin recognition complex subunit 6 0.148
Cul-5 Cullin-5 0.145
par-1 CG8201 gene product from transcript CG8201-RA 0.141
esg escargot 0.132
Pp2A-29B Protein phosphatase 2A at 29B 0.131
CG14667 CG14667 gene product from transcript CG14667-RA 0.130
rho rhomboid 0.128
msn misshapen 0.124
chb chromosome bows 0.123
Max CG9648 gene product from transcript CG9648-RA 0.122
Myb Myb oncogene-like 0.121
Spc25 CG7242 gene product from transcript CG7242-RA 0.121
Bj1 Bj1 protein 0.119
hipk homeodomain interacting protein kinase 0.117
sina seven in absentia 0.112
CG5199 CG5199 gene product from transcript CG5199-RA 0.111
dlg1 discs large 1 0.110
cnn centrosomin 0.108
Cdk4 Cyclin-dependent kinase 4 0.106
zpg zero population growth 0.105
mub mushroom-body expressed 0.103
Cortactin CG3637 gene product from transcript CG3637-RA 0.102
cas castor 0.099
ens ensconsin 0.098
rok Rho-kinase 0.094
alpha-Adaptin CG4260 gene product from transcript CG4260-RA 0.093
aPKC atypical protein kinase C 0.093
polo CG12306 gene product from transcript CG12306-RA 0.092
l(2)gl lethal (2) giant larvae 0.090
l(2)05714 lethal (2) 05714 0.089
CG6843 CG6843 gene product from transcript CG6843-RA 0.086
chic chickadee 0.085
inaD inactivation no afterpotential D 0.084
CycD Cyclin D 0.083
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Homo sapiens
Name Description Probability Func Analog Organism
PRKCZ protein kinase C, zeta 1.000
CCT8 chaperonin containing TCP1, subunit 8 (theta) 1.000
STK11 serine/threonine kinase 11 1.000
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 1.000
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 1.000
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.999
CDK2 cyclin-dependent kinase 2 0.998
TCP1 t-complex 1 0.996
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.986
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.983
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.982
MAPT microtubule-associated protein tau 0.978
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.978
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.974
PPP4C protein phosphatase 4, catalytic subunit 0.972
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.966
CENPJ centromere protein J 0.964
STRADA STE20-related kinase adaptor alpha 0.946
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.938
ZBED1 zinc finger, BED-type containing 1 0.903
PRKCI protein kinase C, iota 0.883
JUB jub, ajuba homolog (Xenopus laevis) 0.837
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.824
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.772
STRN3 striatin, calmodulin binding protein 3 0.768
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.712
CCNB1 cyclin B1 0.702
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.681
PKP2 plakophilin 2 0.672
STRADB STE20-related kinase adaptor beta 0.649
TNIP2 TNFAIP3 interacting protein 2 0.618
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.606
MARK2 MAP/microtubule affinity-regulating kinase 2 0.589
NCF2 neutrophil cytosolic factor 2 0.578
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.554
SFN stratifin 0.544
CCDC158 coiled-coil domain containing 158 0.536
NGF nerve growth factor (beta polypeptide) 0.516
PPP2R1B protein phosphatase 2, regulatory subunit A, beta 0.515
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.451
MARK4 MAP/microtubule affinity-regulating kinase 4 0.432
CAB39 calcium binding protein 39 0.385
AP2A1 adaptor-related protein complex 2, alpha 1 subunit 0.384
SKA3 spindle and kinetochore associated complex subunit 3 0.358
SKP2 S-phase kinase-associated protein 2 (p45) 0.327
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1 0.319
PLCG1 phospholipase C, gamma 1 0.316
CCNB2 cyclin B2 0.302
CCNE1 cyclin E1 0.283
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.266
RFWD2 ring finger and WD repeat domain 2 0.259
MOBKL3 MOB1, Mps One Binder kinase activator-like 3 (yeast) 0.254
NUMA1 nuclear mitotic apparatus protein 1 0.243
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.242
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.239
F11R F11 receptor 0.236
CCT6A chaperonin containing TCP1, subunit 6A (zeta 1) 0.235
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.224
OXSR1 oxidative-stress responsive 1 0.218
STK39 serine threonine kinase 39 0.210
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.210
PKP3 plakophilin 3 0.208
BCAR1 breast cancer anti-estrogen resistance 1 0.196
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.176
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.173
GNG2 guanine nucleotide binding protein (G protein), gamma 2 0.169
CAPZB capping protein (actin filament) muscle Z-line, beta 0.168
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.164
SASS6 spindle assembly 6 homolog (C. elegans) 0.163
VHL von Hippel-Lindau tumor suppressor 0.161
MAP2K5 mitogen-activated protein kinase kinase 5 0.149
CDH5 cadherin 5, type 2 (vascular endothelium) 0.148
TRAF5 TNF receptor-associated factor 5 0.148
NTF4 neurotrophin 4 0.147
CKS2 CDC28 protein kinase regulatory subunit 2 0.136
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 0.136
HMGB2 high mobility group box 2 0.136
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4 0.122
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.107
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.107
ZNF71 zinc finger protein 71 0.107
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.099
FYN FYN oncogene related to SRC, FGR, YES 0.098
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.097
C22orf39 chromosome 22 open reading frame 39 0.095
IQGAP2 IQ motif containing GTPase activating protein 2 0.094
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.094
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7 0.093
CKS1B CDC28 protein kinase regulatory subunit 1B 0.087
KIF23 kinesin family member 23 0.087
MOBKL1A MOB1, Mps One Binder kinase activator-like 1A (yeast) 0.087
MARK1 MAP/microtubule affinity-regulating kinase 1 0.085
SQSTM1 sequestosome 1 0.084
NUMB numb homolog (Drosophila) 0.084
PPME1 protein phosphatase methylesterase 1 0.078
TP53 tumor protein p53 0.077
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 0.075
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.074
STIL SCL/TAL1 interrupting locus 0.074
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.072
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism