IMP
Process View
The network for 'positive regulation of kidney development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of kidney development
Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pax8 | paired box gene 8 | 0.999 | |
| Shh | sonic hedgehog | 0.999 | |
| Foxc2 | forkhead box C2 | 0.986 | |
| Fgf8 | fibroblast growth factor 8 | 0.984 | |
| Pax2 | paired box gene 2 | 0.984 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.979 | |
| Pax3 | paired box gene 3 | 0.977 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.977 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.962 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.959 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.949 | |
| Sox2 | SRY-box containing gene 2 | 0.910 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.894 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.883 | |
| Pax6 | paired box gene 6 | 0.852 | |
| Sox7 | SRY-box containing gene 7 | 0.835 | |
| Lhx3 | LIM homeobox protein 3 | 0.823 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.821 | |
| Lhx1 | LIM homeobox protein 1 | 0.808 | |
| Wt1 | Wilms tumor 1 homolog | 0.807 | |
| Hoxa1 | homeobox A1 | 0.806 | |
| Ren1 | renin 1 structural | 0.803 | |
| Ret | ret proto-oncogene | 0.799 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.797 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.797 | |
| Flt4 | FMS-like tyrosine kinase 4 | 0.795 | |
| Vegfa | vascular endothelial growth factor A | 0.790 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.768 | |
| Fgf10 | fibroblast growth factor 10 | 0.748 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.727 | |
| Msx1 | homeobox, msh-like 1 | 0.722 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.695 | |
| Bmp4 | bone morphogenetic protein 4 | 0.694 | |
| Hoxa10 | homeobox A10 | 0.665 | |
| Hoxa2 | homeobox A2 | 0.629 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.623 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.618 | |
| Hoxc8 | homeobox C8 | 0.613 | |
| Hoxa11 | homeobox A11 | 0.596 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.573 | |
| Foxc1 | forkhead box C1 | 0.571 | |
| Bnc1 | basonuclin 1 | 0.544 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.529 | |
| Nog | noggin | 0.521 | |
| Hoxd9 | homeobox D9 | 0.514 | |
| Prrx2 | paired related homeobox 2 | 0.512 | |
| Hoxa3 | homeobox A3 | 0.491 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.486 | |
| Hoxa4 | homeobox A4 | 0.477 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.475 | |
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.474 | |
| Hoxa9 | homeobox A9 | 0.441 | |
| Tbx2 | T-box 2 | 0.437 | |
| Hoxc5 | homeobox C5 | 0.434 | |
| Hoxb6 | homeobox B6 | 0.417 | |
| C1qc | complement component 1, q subcomponent, C chain | 0.410 | |
| Dlx5 | distal-less homeobox 5 | 0.408 | |
| Gata4 | GATA binding protein 4 | 0.407 | |
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.407 | |
| Tbx1 | T-box 1 | 0.401 | |
| Hoxd11 | homeobox D11 | 0.399 | |
| Hoxb5 | homeobox B5 | 0.399 | |
| Cyp26a1 | cytochrome P450, family 26, subfamily a, polypeptide 1 | 0.399 | |
| Hoxd4 | homeobox D4 | 0.395 | |
| Fgf3 | fibroblast growth factor 3 | 0.391 | |
| Gata6 | GATA binding protein 6 | 0.371 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.366 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.356 | |
| Lhx9 | LIM homeobox protein 9 | 0.348 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.340 | |
| Nr0b1 | nuclear receptor subfamily 0, group B, member 1 | 0.339 | |
| Alx4 | aristaless-like homeobox 4 | 0.338 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.329 | |
| Fshr | follicle stimulating hormone receptor | 0.320 | |
| Amh | anti-Mullerian hormone | 0.297 | |
| T | brachyury | 0.292 | |
| Ar | androgen receptor | 0.278 | |
| Hoxb4 | homeobox B4 | 0.277 | |
| Foxa2 | forkhead box A2 | 0.277 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.275 | |
| Rarg | retinoic acid receptor, gamma | 0.274 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.271 | |
| Hoxa5 | homeobox A5 | 0.268 | |
| Rarb | retinoic acid receptor, beta | 0.259 | |
| Prrx1 | paired related homeobox 1 | 0.257 | |
| Hoxd10 | homeobox D10 | 0.257 | |
| Phox2b | paired-like homeobox 2b | 0.235 | |
| Tbx3 | T-box 3 | 0.234 | |
| Hoxc4 | homeobox C4 | 0.234 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.232 | |
| Ngfr | nerve growth factor receptor (TNFR superfamily, member 16) | 0.228 | |
| Alx3 | aristaless-like homeobox 3 | 0.227 | |
| Kiss1 | KiSS-1 metastasis-suppressor | 0.223 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.219 | |
| Hoxc6 | homeobox C6 | 0.218 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.214 | |
| Nos2 | nitric oxide synthase 2, inducible | 0.211 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.209 | |
| Nkx2-1 | NK2 homeobox 1 | 0.207 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.206 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.861 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.181 | |
| VEGFA | vascular endothelial growth factor A | 0.076 | |
| NRP1 | neuropilin 1 | 0.071 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.056 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.054 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.044 | |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.032 | |
| FSTL1 | follistatin-like 1 | 0.021 | |
| PJA1 | praja ring finger 1 | 0.013 | |
| SNAI1 | snail homolog 1 (Drosophila) | 0.012 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.012 | |
| NKX2-1 | NK2 homeobox 1 | 0.011 |