The network for 'tissue migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

tissue migration

The process in which the population of cells that make up a tissue undergo directed movement.

Danio rerio
Name Description Probability Func Analog Organism
kdrl kinase insert domain receptor like 0.884
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.790
fgfr3 fibroblast growth factor receptor 3 0.673
vegfc vascular endothelial growth factor c 0.672
kita kit receptor a 0.628
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.624
tbx2b T-box 2b 0.620
efnb2a ephrin B2a 0.601
itgb1b integrin, beta 1b 0.584
itgb1b.2 integrin, beta 1b.2 0.578
mmp2 matrix metalloproteinase 2 0.575
sox9a SRY-box containing gene 9a 0.531
bmp4 bone morphogenetic protein 4 0.493
notch3 notch homolog 3 0.484
plcg1 phospholipase C, gamma 1 0.328
crb2a crumbs homolog 2a 0.328
slit2 slit (Drosophila) homolog 2 0.285
aox3 aldehyde oxidase 3 0.275
slit3 slit (Drosophila) homolog 3 0.264
ccm2 cerebral cavernous malformation 2 0.256
neo1 neogenin 1 0.246
cdh5 cadherin 5 0.243
crabp2a cellular retinoic acid binding protein 2, a 0.240
pax2a paired box gene 2a 0.235
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.233
cdh23 cadherin-like 23 0.225
neurog1 neurogenin 1 0.222
ptprf protein tyrosine phosphatase, receptor type, F 0.213
vegfaa vascular endothelial growth factor Aa 0.203
etv2 ets variant gene 2 0.203
si:ch211-212m21.5 si:ch211-212m21.5 0.202
prox1 prospero-related homeobox gene 1 0.200
cav1 caveolin 1 0.199
dll4 delta-like 4 (Drosophila) 0.193
spry4 sprouty (Drosophila) homolog 4 0.180
fgf3 fibroblast growth factor 3 0.174
pitx3 paired-like homeodomain transcription factor 3 0.171
prrx1a paired related homeobox 1a 0.165
cdh2 cadherin 2, neuronal 0.160
pak2a p21 (CDKN1A)-activated kinase 2a 0.155
tbx16 T-box gene 16 0.154
nrp2a neuropilin 2a 0.153
pcdh8 protocadherin 8 0.148
smo smoothened homolog (Drosophila) 0.146
dusp5 dual specificity phosphatase 5 0.145
pdlim1 PDZ and LIM domain 1 (elfin) 0.144
gpr126 G protein-coupled receptor 126 0.144
ascl1a achaete-scute complex-like 1a (Drosophila) 0.139
itgb1a integrin, beta 1a 0.135
ptch2 patched 2 0.128
egr1 early growth response 1 0.127
tpm4 tropomyosin 4 0.127
dld deltaD 0.122
bmp2b bone morphogenetic protein 2b 0.121
lmo2 LIM domain only 2 (rhombotin-like 1) 0.119
lyz lysozyme 0.107
pxn paxillin 0.106
lpp LIM domain containing preferred translocation partner in lipoma 0.101
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.101
epas1b endothelial PAS domain protein 1b 0.099
myf5 myogenic factor 5 0.097
wnt11r wingless-type MMTV integration site family, member 11, related 0.095
gsna gelsolin a 0.093
fn1b fibronectin 1b 0.091
boc brother of CDO 0.089
mef2d myocyte enhancer factor 2d 0.089
ntn1a netrin 1a 0.089
pax7a paired box gene 7a 0.088
tie2 endothelium-specific receptor tyrosine kinase 2 0.087
tal1 T-cell acute lymphocytic leukemia 1 0.087
unc5b unc-5 homolog B (C. elegans) 0.087
ptgs1 prostaglandin-endoperoxide synthase 1 0.087
shha sonic hedgehog a 0.085
gata2a GATA-binding protein 2a 0.084
wnt11 wingless-type MMTV integration site family, member 11 0.084
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.082
appb amyloid beta (A4) precursor protein b 0.082
dlx5a distal-less homeobox gene 5a 0.081
dlb deltaB 0.080
si:ch73-60e21.1 si:ch73-60e21.1 0.080
bnc2 basonuclin 2 0.080
mtmr8 myotubularin related protein 8 0.079
bmpr2a bone morphogenetic protein receptor, type II a (serine/threonine kinase) 0.079
wnt7ba wingless-type MMTV integration site family, member 7Ba 0.077
emx3 empty spiracles homeobox 3 0.075
chrna6 cholinergic receptor, nicotinic, alpha 6 0.073
nrp1a neuropilin 1a 0.072
gbx2 gastrulation brain homeo box 2 0.071
cntn2 contactin 2 0.070
fn1 fibronectin 1 0.070
cxcr4b chemokine (C-X-C motif), receptor 4b 0.069
gdf6a growth differentiation factor 6a 0.069
krit1 KRIT1, ankyrin repeat containing 0.067
plod1a procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a 0.066
gata3 GATA-binding protein 3 0.066
itgb3b integrin beta 3b 0.066
meis1 myeloid ecotropic viral integration 1 0.066
plxnd1 plexin D1 0.063
fgf10a fibroblast growth factor 10a 0.062
tgfb1a transforming growth factor, beta 1a 0.062
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Rac1 CG2248 gene product from transcript CG2248-RA 1.000
mbc myoblast city 1.000
par-1 CG8201 gene product from transcript CG8201-RA 1.000
tkv thickveins 0.999
yu CG3249 gene product from transcript CG3249-RA 0.999
Shc SHC-adaptor protein 0.999
Rala Ras-related protein 0.998
ttk tramtrack 0.998
CG8155 CG8155 gene product from transcript CG8155-RA 0.998
Ras85D Ras oncogene at 85D 0.998
dome domeless 0.997
Mrtf Myocardin-related transcription factor 0.997
Ced-12 CG5336 gene product from transcript CG5336-RA 0.996
BicD Bicaudal D 0.995
EcR Ecdysone receptor 0.994
aop anterior open 0.991
Cortactin CG3637 gene product from transcript CG3637-RA 0.991
zip zipper 0.990
cpb capping protein beta 0.989
chic chickadee 0.983
Pten CG5671 gene product from transcript CG5671-RB 0.970
pnt pointed 0.970
shi shibire 0.965
stai stathmin 0.964
spi spitz 0.964
Stat92E Signal-transducer and activator of transcription protein at 92E 0.963
Krn Keren 0.958
hep hemipterous 0.957
Rho1 CG8416 gene product from transcript CG8416-RB 0.949
ex expanded 0.946
kuz kuzbanian 0.945
dsh dishevelled 0.942
Egfr Epidermal growth factor receptor 0.942
fz frizzled 0.940
Pvr PDGF- and VEGF-receptor related 0.940
Pvf1 PDGF- and VEGF-related factor 1 0.936
Rab5 Rab-protein 5 0.933
kibra kibra ortholog 0.930
mew multiple edematous wings 0.925
grk gurken 0.920
baz bazooka 0.918
sqh spaghetti squash 0.915
emc extra macrochaetae 0.914
nudE CG8104 gene product from transcript CG8104-RB 0.912
Ets97D Ets at 97D 0.908
jar jaguar 0.901
Socs36E Suppressor of cytokine signaling at 36E 0.894
Tm1 Tropomyosin 1 0.893
Cbl CG7037 gene product from transcript CG7037-RB 0.890
mys myospheroid 0.886
shg shotgun 0.881
rl rolled 0.881
Pxt Peroxinectin-like 0.879
alpha-Cat alpha Catenin 0.878
CalpB Calpain-B 0.878
loco locomotion defects 0.877
stumps CG31317 gene product from transcript CG31317-RC 0.868
scb scab 0.868
Fas2 Fasciclin 2 0.863
Caki Calcium/calmodulin-dependent protein kinase 0.862
rho rhomboid 0.860
RhoL rho-like 0.857
Alk CG8250 gene product from transcript CG8250-RA 0.853
CG6509 CG6509 gene product from transcript CG6509-RB 0.853
btl breathless 0.846
Fmr1 CG6203 gene product from transcript CG6203-RC 0.842
Hph HIF prolyl hydroxylase 0.828
kst karst 0.800
kis kismet 0.798
cher cheerio 0.774
CaMKII Calcium/calmodulin-dependent protein kinase II 0.771
lkb1 CG9374 gene product from transcript CG9374-RJ 0.771
par-6 CG5884 gene product from transcript CG5884-RA 0.768
Dhc64C Dynein heavy chain 64C 0.766
bnl branchless 0.762
shd shade 0.760
lea leak 0.754
dos daughter of sevenless 0.752
slbo slow border cells 0.752
rhea CG6831 gene product from transcript CG6831-RA 0.748
cindr CIN85 and CD2AP orthologue 0.744
drk downstream of receptor kinase 0.737
lqf liquid facets 0.733
fkh fork head 0.729
bbg big bang 0.728
R Roughened 0.726
sev sevenless 0.723
tj traffic jam 0.721
bs blistered 0.718
tai taiman 0.715
bin biniou 0.708
jing CG9397 gene product from transcript CG9397-RI 0.701
Cdc42 CG12530 gene product from transcript CG12530-RA 0.700
Src42A Src oncogene at 42A 0.681
usp ultraspiracle 0.677
Mad Mothers against dpp 0.672
wg wingless 0.664
sli slit 0.656
bsk basket 0.653
l(2)gl lethal (2) giant larvae 0.653
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Homo sapiens
Name Description Probability Func Analog Organism
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
EGFR epidermal growth factor receptor 0.995
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.990
FGFR2 fibroblast growth factor receptor 2 0.986
TEK TEK tyrosine kinase, endothelial 0.986
JAG1 jagged 1 0.985
LCK lymphocyte-specific protein tyrosine kinase 0.981
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.981
VEGFA vascular endothelial growth factor A 0.970
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.969
FGF1 fibroblast growth factor 1 (acidic) 0.969
FN1 fibronectin 1 0.964
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.960
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.956
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.952
GRB7 growth factor receptor-bound protein 7 0.947
S100B S100 calcium binding protein B 0.938
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.932
LAT linker for activation of T cells 0.928
RARA retinoic acid receptor, alpha 0.920
ENG endoglin 0.915
TGFB1 transforming growth factor, beta 1 0.888
PPL periplakin 0.877
JUN jun proto-oncogene 0.874
ANXA1 annexin A1 0.867
S100A6 S100 calcium binding protein A6 0.865
S100A8 S100 calcium binding protein A8 0.844
NRP1 neuropilin 1 0.841
YAP1 Yes-associated protein 1 0.833
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.804
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.794
S100A14 S100 calcium binding protein A14 0.787
BMPR1A bone morphogenetic protein receptor, type IA 0.762
SMAD1 SMAD family member 1 0.762
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.758
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.745
VCAM1 vascular cell adhesion molecule 1 0.738
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.736
KRT17 keratin 17 0.732
GRB2 growth factor receptor-bound protein 2 0.726
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.713
NCF1 neutrophil cytosolic factor 1 0.712
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.696
FLNA filamin A, alpha 0.695
TPM4 tropomyosin 4 0.693
KLF4 Kruppel-like factor 4 (gut) 0.673
FYN FYN oncogene related to SRC, FGR, YES 0.659
MEF2C myocyte enhancer factor 2C 0.642
MAPK1 mitogen-activated protein kinase 1 0.637
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.628
THBS1 thrombospondin 1 0.627
SFN stratifin 0.625
SKIL SKI-like oncogene 0.622
NOTCH3 notch 3 0.618
KRT14 keratin 14 0.616
DUSP1 dual specificity phosphatase 1 0.610
ANXA2 annexin A2 0.593
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.588
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.587
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.583
ABI2 abl-interactor 2 0.564
CDH5 cadherin 5, type 2 (vascular endothelium) 0.525
KRT19 keratin 19 0.520
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.511
EGR1 early growth response 1 0.504
TIMP1 TIMP metallopeptidase inhibitor 1 0.492
EGR2 early growth response 2 0.490
KLK10 kallikrein-related peptidase 10 0.473
S100A11 S100 calcium binding protein A11 0.472
EGR3 early growth response 3 0.465
MEF2A myocyte enhancer factor 2A 0.461
NOTCH1 notch 1 0.460
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.450
TP63 tumor protein p63 0.441
TRIM29 tripartite motif containing 29 0.433
FGFR1 fibroblast growth factor receptor 1 0.424
ZYX zyxin 0.419
CTGF connective tissue growth factor 0.419
MAP3K3 mitogen-activated protein kinase kinase kinase 3 0.406
PRKCA protein kinase C, alpha 0.399
SYK spleen tyrosine kinase 0.396
FGA fibrinogen alpha chain 0.393
BMP2 bone morphogenetic protein 2 0.391
CYR61 cysteine-rich, angiogenic inducer, 61 0.381
PTPRJ protein tyrosine phosphatase, receptor type, J 0.372
S100A4 S100 calcium binding protein A4 0.365
TSC22D1 TSC22 domain family, member 1 0.353
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.345
SP100 SP100 nuclear antigen 0.345
PTK2 PTK2 protein tyrosine kinase 2 0.334
BMPR1B bone morphogenetic protein receptor, type IB 0.329
BTK Bruton agammaglobulinemia tyrosine kinase 0.329
ALB albumin 0.329
VEGFC vascular endothelial growth factor C 0.329
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.325
PLAU plasminogen activator, urokinase 0.319
PTPRB protein tyrosine phosphatase, receptor type, B 0.317
FKBP1A FK506 binding protein 1A, 12kDa 0.316
KLK7 kallikrein-related peptidase 7 0.304
AMOT angiomotin 0.302
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Mus musculus
Name Description Probability Func Analog Organism
Efnb2 ephrin B2 0.999
Pax2 paired box gene 2 0.994
Jag1 jagged 1 0.980
Nos3 nitric oxide synthase 3, endothelial cell 0.973
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.970
Gata4 GATA binding protein 4 0.966
Fgfr2 fibroblast growth factor receptor 2 0.964
Fgfr1 fibroblast growth factor receptor 1 0.958
Zeb1 zinc finger E-box binding homeobox 1 0.947
Fgf10 fibroblast growth factor 10 0.944
Notch1 Notch gene homolog 1 (Drosophila) 0.943
Eng endoglin 0.927
Ptk2 PTK2 protein tyrosine kinase 2 0.922
Ptprb protein tyrosine phosphatase, receptor type, B 0.906
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.886
Fgf8 fibroblast growth factor 8 0.882
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.876
Hif1a hypoxia inducible factor 1, alpha subunit 0.871
Flt4 FMS-like tyrosine kinase 4 0.854
Flt1 FMS-like tyrosine kinase 1 0.852
Bmp4 bone morphogenetic protein 4 0.833
Sox2 SRY-box containing gene 2 0.756
Kdr kinase insert domain protein receptor 0.746
Pax3 paired box gene 3 0.745
Gata6 GATA binding protein 6 0.731
Slit3 slit homolog 3 (Drosophila) 0.715
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.677
Nrp1 neuropilin 1 0.672
Lrp1 low density lipoprotein receptor-related protein 1 0.667
Vegfa vascular endothelial growth factor A 0.651
Hand2 heart and neural crest derivatives expressed transcript 2 0.647
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.621
Ephb2 Eph receptor B2 0.614
Notch2 Notch gene homolog 2 (Drosophila) 0.603
Shh sonic hedgehog 0.602
Gli3 GLI-Kruppel family member GLI3 0.596
Epha4 Eph receptor A4 0.593
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.558
Sox18 SRY-box containing gene 18 0.545
Lepr leptin receptor 0.539
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.527
Amh anti-Mullerian hormone 0.519
Egfr epidermal growth factor receptor 0.516
Csf1 colony stimulating factor 1 (macrophage) 0.499
Bcl2 B-cell leukemia/lymphoma 2 0.499
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.483
Pax6 paired box gene 6 0.478
Foxf1a forkhead box F1a 0.475
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 0.470
Nos2 nitric oxide synthase 2, inducible 0.457
She src homology 2 domain-containing transforming protein E 0.456
Pitx1 paired-like homeodomain transcription factor 1 0.451
Pax8 paired box gene 8 0.445
Cyr61 cysteine rich protein 61 0.430
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.429
Rxra retinoid X receptor alpha 0.411
Col4a2 collagen, type IV, alpha 2 0.404
Hoxa11 homeobox A11 0.403
Lhx1 LIM homeobox protein 1 0.401
Bmp5 bone morphogenetic protein 5 0.401
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.401
Nkx2-1 NK2 homeobox 1 0.399
Ctnnb1 catenin (cadherin associated protein), beta 1 0.397
Cldn5 claudin 5 0.395
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.394
Egfl7 EGF-like domain 7 0.390
Cdh5 cadherin 5 0.387
Ncor2 nuclear receptor co-repressor 2 0.384
Snai1 snail homolog 1 (Drosophila) 0.384
Foxf2 forkhead box F2 0.363
Sox7 SRY-box containing gene 7 0.355
Foxc1 forkhead box C1 0.352
Cxcl12 chemokine (C-X-C motif) ligand 12 0.350
Sox9 SRY-box containing gene 9 0.349
Robo1 roundabout homolog 1 (Drosophila) 0.347
Ret ret proto-oncogene 0.347
Pou3f3 POU domain, class 3, transcription factor 3 0.339
Pcdh12 protocadherin 12 0.333
Acvr1 activin A receptor, type 1 0.325
Kit kit oncogene 0.323
Ntf3 neurotrophin 3 0.303
Spry4 sprouty homolog 4 (Drosophila) 0.301
Tgfb1 transforming growth factor, beta 1 0.301
Hoxd11 homeobox D11 0.298
Onecut1 one cut domain, family member 1 0.297
Apoe apolipoprotein E 0.289
Fjx1 four jointed box 1 (Drosophila) 0.286
Pten phosphatase and tensin homolog 0.283
Smad6 MAD homolog 6 (Drosophila) 0.280
Otx1 orthodenticle homolog 1 (Drosophila) 0.279
Esam endothelial cell-specific adhesion molecule 0.271
Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 0.269
Msn moesin 0.268
Notch3 Notch gene homolog 3 (Drosophila) 0.268
Efnb1 ephrin B1 0.266
Tlx3 T-cell leukemia, homeobox 3 0.262
Prox1 prospero-related homeobox 1 0.260
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.259
Hand1 heart and neural crest derivatives expressed transcript 1 0.258
Gpr50 G-protein-coupled receptor 50 0.256
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Rattus norvegicus
Name Description Probability Func Analog Organism
Nfib nuclear factor I/B 0.030
Nfia nuclear factor I/A 0.022
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.022
Slit3 slit homolog 3 (Drosophila) 0.018
Fos FBJ osteosarcoma oncogene 0.017
Fcgrt Fc fragment of IgG, receptor, transporter, alpha 0.015
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.015
Klf2 Kruppel-like factor 2 (lung) 0.015
Spt1 salivary protein 1 0.014
Bgn biglycan 0.014
Hoxa2 homeo box A2 0.013
Ednrb endothelin receptor type B 0.012
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.012
Fosl1 fos-like antigen 1 0.011
Flt1 FMS-related tyrosine kinase 1 0.011
Grm5 glutamate receptor, metabotropic 5 0.011
Fuca1 fucosidase, alpha-L- 1, tissue 0.011
Npr1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 0.010
Prg2 proteoglycan 2, bone marrow 0.010
Smad7 SMAD family member 7 0.010
Rxra retinoid X receptor alpha 0.010
Cd2 Cd2 molecule 0.010
RGD1309414 similar to KIAA0913 protein 0.010
Vom2r44 vomeronasal 2 receptor 44 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism