The network for 'regulation of apoptotic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of apoptotic process

Any process that modulates the occurrence or rate of cell death by apoptotic process.

Danio rerio
Name Description Probability Func Analog Organism
tbx1 T-box 1 0.997
fgf8a fibroblast growth factor 8 a 0.879
col2a1a collagen type II, alpha-1a 0.806
shha sonic hedgehog a 0.797
bmp2b bone morphogenetic protein 2b 0.755
kita kit receptor a 0.679
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.670
fgfr1a fibroblast growth factor receptor 1a 0.635
plcg1 phospholipase C, gamma 1 0.614
ef1a elongation factor 1-alpha 0.611
tbx20 T-box 20 0.593
slc4a4a solute carrier family 4, member 4a 0.581
rarga retinoic acid receptor gamma a 0.577
cdh1 cadherin 1, epithelial 0.566
baxa bcl2-associated X protein, a 0.556
evx1 even-skipped homeobox 1 0.527
chd chordin 0.526
tgfb3 transforming growth factor, beta 3 0.512
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.506
sulf1 sulfatase 1 0.505
bdnf brain-derived neurotrophic factor 0.495
alcama activated leukocyte cell adhesion molecule a 0.491
fgfr3 fibroblast growth factor receptor 3 0.488
sox11a SRY-box containing gene 11a 0.483
nrg1 neuregulin 1 0.472
ndr2 nodal-related 2 0.468
fgf3 fibroblast growth factor 3 0.453
mib mind bomb 0.449
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.447
myod1 myogenic differentiation 1 0.430
gata3 GATA-binding protein 3 0.417
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.410
nrg2a neuregulin 2a 0.404
bbc3 BCL2 binding component 3 0.376
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.373
pdlim1 PDZ and LIM domain 1 (elfin) 0.370
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.370
wnt11r wingless-type MMTV integration site family, member 11, related 0.370
gata5 GATA-binding protein 5 0.359
raraa retinoic acid receptor, alpha a 0.359
grnb granulin b 0.357
slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 0.353
dlx2a distal-less homeobox gene 2a 0.350
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.349
kdrl kinase insert domain receptor like 0.347
spry4 sprouty (Drosophila) homolog 4 0.343
spns2 spinster homolog 2 (Drosophila) 0.342
wnt9b wingless-type MMTV integration site family, member 9B 0.331
mcl1a myeloid cell leukemia sequence 1a 0.330
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.329
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.328
barhl1.2 BarH-like 1.2 0.325
lef1 lymphocyte enhancer binding factor 1 0.320
hspd1 heat shock 60kD protein 1 (chaperonin) 0.316
hand2 heart and neural crest derivatives expressed transcript 2 0.315
sema3aa semaphorin 3aa 0.314
loxl3b lysyl oxidase-like 3b 0.309
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.303
pea3 ETS-domain transcription factor pea3 0.302
piwil2 piwi-like 2 (Drosophila) 0.300
cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.298
ascl1a achaete-scute complex-like 1a (Drosophila) 0.297
pax8 paired box gene 8 0.297
smad3a MAD homolog 3a (Drosophila) 0.293
esco2 establishment of cohesion 1 homolog 2 0.292
dld deltaD 0.288
fzd7a frizzled homolog 7a 0.287
smo smoothened homolog (Drosophila) 0.281
alcamb activated leukocyte cell adhesion molecule b 0.280
dusp6 dual specificity phosphatase 6 0.279
plxnb2a plexin b2a 0.276
stc1l stanniocalcin 1, like 0.276
jag2 jagged 2 0.274
mao monoamine oxidase 0.274
mecp2 methyl CpG binding protein 2 0.274
nadl1.2 neural adhesion molecule L1.2 0.270
pax2a paired box gene 2a 0.268
col14a1 collagen, type XIV, alpha 1 0.268
ptch2 patched 2 0.267
notch1a notch homolog 1a 0.266
itgb1b integrin, beta 1b 0.260
hspa5 heat shock protein 5 0.252
bcl2l1 bcl2-like 1 0.252
efnb2a ephrin B2a 0.250
gsc goosecoid 0.248
hdac1 histone deacetylase 1 0.247
xbp1 X-box binding protein 1 0.246
gpr126 G protein-coupled receptor 126 0.246
max myc-associated factor X 0.245
tpm4 tropomyosin 4 0.242
neo1 neogenin 1 0.241
dla deltaA 0.237
krit1 KRIT1, ankyrin repeat containing 0.235
her6 hairy-related 6 0.234
id3 inhibitor of DNA binding 3 0.234
slc2a12 solute carrier family 2 (facilitated glucose transporter), member 12 0.231
tp53 tumor protein p53 0.230
aurkb aurora kinase B 0.229
rpsa ribosomal protein SA 0.227
hoxa4a homeo box A4a 0.226
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
hsp-1 Protein HSP-1 0.679
egl-18 Protein EGL-18 0.376
soc-2 Protein SOC-2 0.294
egl-46 Protein EGL-46 0.234
hcp-3 Protein HCP-3 0.201
eef-1A.1 Protein EEF-1A.1 0.190
par-5 Protein PAR-5 0.158
F31D4.2 Protein F31D4.2 0.124
CELE_C12D8.1 Protein C12D8.1 0.119
lmn-1 Protein LMN-1 0.117
pry-1 Protein PRY-1 0.115
bar-1 Protein BAR-1 0.115
F36D4.5 Protein F36D4.5 0.110
eps-8 Protein EPS-8 0.109
let-502 Protein LET-502 0.109
rpt-3 Protein RPT-3 0.104
sma-6 Protein SMA-6 0.103
mat-3 Protein MAT-3 0.100
ceh-20 Protein CEH-20 0.097
F36A2.13 Protein F36A2.13 0.091
rad-26 Protein RAD-26 0.090
nasp-1 Protein NASP-1 0.085
F39B2.1 Protein F39B2.1 0.084
egl-30 Protein EGL-30 0.081
vab-3 Protein VAB-3 0.076
pal-1 Protein PAL-1 0.076
daf-21 Protein DAF-21 0.074
rla-0 Protein RLA-0 0.073
nrde-2 Protein NRDE-2 0.072
fkh-2 Protein FKH-2 0.071
let-60 Protein LET-60 0.071
gld-1 Protein GLD-1 0.070
flt-1 Protein FLT-1 0.069
unc-52 Protein UNC-52 0.069
fem-2 Protein FEM-2 0.068
atg-18 Protein ATG-18 0.067
mab-31 Protein MAB-31 0.066
unc-73 Protein UNC-73 0.065
F31C3.2 Protein F31C3.2 0.064
let-756 Protein LET-756 0.064
dbr-1 Protein DBR-1 0.064
imb-2 Protein IMB-2 0.064
hum-6 Protein HUM-6 0.063
R74.8 Protein R74.8 0.063
crt-1 Protein CRT-1 0.060
rpl-6 Protein RPL-6 0.060
K10D6.4 Protein K10D6.4 0.060
icd-1 Protein ICD-1 0.060
egl-5 Protein EGL-5 0.059
byn-1 Protein BYN-1 0.057
sta-1 Protein STA-1 0.057
htz-1 Protein HTZ-1 0.057
CELE_Y48B6A.1 Protein Y48B6A.1 0.056
sax-7 Protein SAX-7 0.056
CELE_C18C4.5 Protein C18C4.5 0.056
nhr-45 Protein NHR-45 0.055
CELE_F14E5.2 Protein F14E5.2 0.055
lin-1 Protein LIN-1 0.055
unc-60 Protein UNC-60 0.054
ant-1.1 Protein ANT-1.1 0.054
tbb-2 Protein TBB-2 0.054
kin-3 Protein KIN-3 0.051
trap-4 Protein TRAP-4 0.050
spr-4 Protein SPR-4 0.050
vrk-1 Protein VRK-1 0.049
rpa-1 Protein RPA-1 0.049
C28H8.3 Protein C28H8.3 0.048
drp-1 Protein DRP-1 0.047
cpt-1 Protein CPT-1 0.047
rig-6 Protein RIG-6 0.047
ifg-1 Protein IFG-1 0.046
tct-1 Protein TCT-1 0.045
emo-1 Protein EMO-1 0.045
zyg-11 Protein ZYG-11 0.045
trim-9 Protein TRIM-9 0.044
ceh-44 Protein CEH-44 0.044
nhr-67 Protein NHR-67 0.044
ostd-1 Protein OSTD-1 0.043
ceh-38 Protein CEH-38 0.043
CELE_T05E11.3 Protein T05E11.3 0.042
nspa-8 Protein NSPA-8 0.042
atp-2 Protein ATP-2 0.042
rpl-4 Protein RPL-4 0.042
C53B4.4 Protein C53B4.4 0.041
unc-85 Protein UNC-85 0.041
T23F11.1 Protein T23F11.1 0.041
dpy-22 Protein DPY-22 0.041
rars-1 Protein RARS-1 0.040
pek-1 Protein PEK-1 0.040
ceh-27 Protein CEH-27 0.040
pmk-1 Protein PMK-1 0.040
rpl-18 Protein RPL-18 0.040
rnr-2 Protein RNR-2 0.040
lin-11 Protein LIN-11 0.040
H21P03.2 Protein H21P03.2 0.040
osm-3 Protein OSM-3 0.039
eya-1 Protein EYA-1 0.038
puf-8 Protein PUF-8 0.038
hum-5 Protein HUM-5 0.038
ztf-7 Protein ZTF-7 0.038
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Drosophila melanogaster
Name Description Probability Func Analog Organism
nej nejire 0.998
Akt1 CG4006 gene product from transcript CG4006-RA 0.997
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.995
Pten CG5671 gene product from transcript CG5671-RB 0.978
slmb supernumerary limbs 0.975
Ras85D Ras oncogene at 85D 0.960
ci cubitus interruptus 0.951
Egfr Epidermal growth factor receptor 0.949
dm diminutive 0.945
kay kayak 0.896
InR Insulin-like receptor 0.866
lea leak 0.860
gig gigas 0.850
drk downstream of receptor kinase 0.845
crol crooked legs 0.801
Rac1 CG2248 gene product from transcript CG2248-RA 0.747
usp ultraspiracle 0.724
Mad Mothers against dpp 0.724
put punt 0.685
RASSF8 CG5053 gene product from transcript CG5053-RA 0.681
rl rolled 0.669
Antp Antennapedia 0.659
debcl death executioner Bcl-2 homologue 0.655
tkv thickveins 0.651
tsr twinstar 0.648
phl pole hole 0.622
CG11347 CG11347 gene product from transcript CG11347-RE 0.616
shn schnurri 0.615
elav embryonic lethal abnormal vision 0.584
jar jaguar 0.582
th thread 0.576
CadN Cadherin-N 0.566
Dcp-1 Death caspase-1 0.540
wts warts 0.540
rpr reaper 0.539
S6k RPS6-p70-protein kinase 0.536
jumu jumeau 0.529
jing CG9397 gene product from transcript CG9397-RI 0.525
hep hemipterous 0.519
shot short stop 0.517
bab2 CG9102 gene product from transcript CG9102-RA 0.512
l(2)gl lethal (2) giant larvae 0.503
Ubx Ultrabithorax 0.496
Sir2 CG5216 gene product from transcript CG5216-RA 0.495
Src42A Src oncogene at 42A 0.484
scny scrawny 0.484
lwr lesswright 0.471
Nop60B Nucleolar protein at 60B 0.466
arm armadillo 0.459
wg wingless 0.453
smt3 CG4494 gene product from transcript CG4494-RA 0.451
Mhc Myosin heavy chain 0.450
klu klumpfuss 0.437
nmo nemo 0.434
pbl pebble 0.424
Stim Stromal interaction molecule 0.407
dac dachshund 0.407
hpo hippo 0.405
kn knot 0.404
Sod Superoxide dismutase 0.395
D Dichaete 0.389
ss spineless 0.389
sax saxophone 0.380
Rbf Retinoblastoma-family protein 0.374
kibra kibra ortholog 0.370
Dad Daughters against dpp 0.365
rap retina aberrant in pattern 0.364
Hel25E Helicase at 25E 0.360
dsh dishevelled 0.360
LanA Laminin A 0.351
Aos1 CG12276 gene product from transcript CG12276-RA 0.338
Jra Jun-related antigen 0.333
Myo31DF Myosin 31DF 0.325
Rel Relish 0.320
Rho1 CG8416 gene product from transcript CG8416-RB 0.320
os outstretched 0.319
Vps25 Vacuolar protein sorting 25 0.316
ems empty spiracles 0.314
Su(H) Suppressor of Hairless 0.302
CycG Cyclin G 0.298
sd scalloped 0.297
shi shibire 0.296
puc puckered 0.290
Gap1 GTPase-activating protein 1 0.289
Ace Acetylcholine esterase 0.287
Ser Serrate 0.280
Int6 Int6 homologue 0.278
eIF-4a Eukaryotic initiation factor 4a 0.272
Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE 0.269
Cam Calmodulin 0.269
brm brahma 0.268
ik2 IkappaB kinase-like 2 0.265
CG14869 CG14869 gene product from transcript CG14869-RB 0.262
Ten-m Tenascin major 0.261
Pk61C Protein kinase 61C 0.257
bel belle 0.252
LamC Lamin C 0.252
sgg shaggy 0.251
Stam Signal transducing adaptor molecule 0.249
cora coracle 0.249
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
Dusp1 dual specificity phosphatase 1 0.951
Cd44 Cd44 molecule 0.863
Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.782
Anxa2 annexin A2 0.752
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.744
Hspb1 heat shock protein 1 0.730
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.723
Klf4 Kruppel-like factor 4 (gut) 0.723
Socs3 suppressor of cytokine signaling 3 0.709
Pdia6 protein disulfide isomerase family A, member 6 0.683
Vip vasoactive intestinal peptide 0.678
Egr1 early growth response 1 0.668
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.666
Errfi1 ERBB receptor feedback inhibitor 1 0.659
Ahsg alpha-2-HS-glycoprotein 0.637
Junb jun B proto-oncogene 0.630
Ccnd3 cyclin D3 0.624
Fos FBJ osteosarcoma oncogene 0.586
Arpc1b actin related protein 2/3 complex, subunit 1B 0.584
Anxa4 annexin A4 0.575
Ripk3 receptor-interacting serine-threonine kinase 3 0.570
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.561
Cxcr5 chemokine (C-X-C motif) receptor 5 0.545
Mapk3 mitogen activated protein kinase 3 0.545
Zfp36 zinc finger protein 36 0.544
Tnfsf4 tumor necrosis factor (ligand) superfamily, member 4 0.544
Sdcbp syndecan binding protein 0.541
Cd14 CD14 molecule 0.535
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.529
Csf3 colony stimulating factor 3 (granulocyte) 0.528
Vim vimentin 0.521
Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.495
Agtr1a angiotensin II receptor, type 1a 0.495
Cmtm6 CKLF-like MARVEL transmembrane domain containing 6 0.494
Egr2 early growth response 2 0.490
Pebp1 phosphatidylethanolamine binding protein 1 0.471
Cdc37 cell division cycle 37 homolog (S. cerevisiae) 0.458
Pla1a phospholipase A1 member A 0.454
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.453
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.447
Galr3 galanin receptor 3 0.444
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.440
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.436
Anxa5 annexin A5 0.434
Prlhr prolactin releasing hormone receptor 0.428
Slit3 slit homolog 3 (Drosophila) 0.425
Grm5 glutamate receptor, metabotropic 5 0.423
Impdh2 IMP (inosine monophosphate) dehydrogenase 2 0.419
Prkcg protein kinase C, gamma 0.416
Itgam integrin, alpha M 0.416
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.409
Fgfr2 fibroblast growth factor receptor 2 0.403
Ptger3 prostaglandin E receptor 3 (subtype EP3) 0.402
Foxa3 forkhead box A3 0.401
Trib1 tribbles homolog 1 (Drosophila) 0.397
Stip1 stress-induced phosphoprotein 1 0.395
Cd9 CD9 molecule 0.393
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.392
Ar androgen receptor 0.392
Tcf21 transcription factor 21 0.392
Aldoa aldolase A, fructose-bisphosphate 0.391
Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 0.391
Cpxm2 carboxypeptidase X (M14 family), member 2 0.388
Olr1078 olfactory receptor 1078 0.387
Pkm2 pyruvate kinase, muscle 0.387
Hck hemopoietic cell kinase 0.380
Phlda1 pleckstrin homology-like domain, family A, member 1 0.377
S100a9 S100 calcium binding protein A9 0.377
Msn moesin 0.376
Id3 inhibitor of DNA binding 3 0.375
Fgf10 fibroblast growth factor 10 0.368
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.364
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.359
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.357
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.352
Lgals1 lectin, galactoside-binding, soluble, 1 0.350
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.349
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.349
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.349
Cxcl10 chemokine (C-X-C motif) ligand 10 0.348
Jak2 Janus kinase 2 0.347
Myo1b myosin Ib 0.347
Klf2 Kruppel-like factor 2 (lung) 0.344
Col8a1 collagen, type VIII, alpha 1 0.339
Lepr leptin receptor 0.337
Alb albumin 0.334
Btc betacellulin 0.333
P2rx2 purinergic receptor P2X, ligand-gated ion channel, 2 0.331
Ppbp pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.326
RGD1564327 similar to integrin alpha 8 0.326
Cd63 Cd63 molecule 0.326
Gadd45a growth arrest and DNA-damage-inducible, alpha 0.326
Apoa5 apolipoprotein A-V 0.325
Tspo translocator protein 0.322
Cct4 chaperonin containing Tcp1, subunit 4 (delta) 0.322
Edn1 endothelin 1 0.319
Ctrc chymotrypsin C (caldecrin) 0.318
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.317
Il4ra interleukin 4 receptor, alpha 0.314
Tgfbr2 transforming growth factor, beta receptor II 0.313
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism