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Process View

Drosophila melanogaster

38 genes annotated in fly

encapsulation of foreign target

Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization.

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Known genes in the process in fly Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "encapsulation of foreign target"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "encapsulation of foreign target" (in gray)

Name	Description	Probability	Func Analog Organism
Rac1	CG2248 gene product from transcript CG2248-RA	0.999
alpha-Man-II	alpha Mannosidase II	0.997
Ephrin	CG1862 gene product from transcript CG1862-RA	0.995
proPO-A1	prophenol oxidase A1	0.992
FucT6	alpha1,6-fucosyltransferase	0.989
Eph	Eph receptor tyrosine kinase	0.987
RhoBTB	CG5701 gene product from transcript CG5701-RA	0.980
Flo-2	flotillin 2	0.977
Exn	Ephexin	0.976
alpha-Man-IIb	CG4606 gene product from transcript CG4606-RA	0.975
CG11376	CG11376 gene product from transcript CG11376-RA	0.974
Rac2	CG8556 gene product from transcript CG8556-RA	0.952
CG8193	CG8193 gene product from transcript CG8193-RA	0.951
Hml	Hemolectin	0.933
dia	diaphanous	0.932
vav	CG7893 gene product from transcript CG7893-RB	0.905
CG11874	CG11874 gene product from transcript CG11874-RA	0.813
CG6370	CG6370 gene product from transcript CG6370-RA	0.806
gl	glass	0.766
CG42377	CG42377 gene product from transcript CG42377-RA	0.752
Shc	SHC-adaptor protein	0.746
alpha-Man-I	alpha Mannosidase I	0.721
PGRP-LC	Peptidoglycan recognition protein LC	0.625
RhoL	rho-like	0.539
Eb1	CG3265 gene product from transcript CG3265-RF	0.528
Cdc42	CG12530 gene product from transcript CG12530-RA	0.463
Mgat1	UDP-GlcNAc:a-3-D-mannoside-beta-1,2-N-acetylglucosaminyltransferase I	0.429
CG42247	CG42247 gene product from transcript CG42247-RC	0.369
betaInt-nu	beta[nu] integrin	0.369
srp	serpent	0.283
CG7830	CG7830 gene product from transcript CG7830-RA	0.280
Obp99b	Odorant-binding protein 99b	0.191
Dhc64C	Dynein heavy chain 64C	0.184
l(3)mbn	lethal (3) malignant blood neoplasm	0.125
tbce	tubulin-specific chaperone E	0.099
Caps	Calcium activated protein for secretion	0.085
NtR	CG6698 gene product from transcript CG6698-RA	0.079
Fbp1	Fat body protein 1	0.060	Fly
Shal	Shaker cognate l	0.054
Adgf-A	Adenosine deaminase-related growth factor A	0.054
Sp7	Serine protease 7	0.051
Arf79F	ADP ribosylation factor 79F	0.048
Nipped-A	CG33554 gene product from transcript CG33554-RE	0.042
Lsp1gamma	Larval serum protein 1 gamma	0.042	Fly
Pvf2	PDGF- and VEGF-related factor 2	0.041
Pvr	PDGF- and VEGF-receptor related	0.041
Fbp2	Fat body protein 2	0.036
CG13962	CG13962 gene product from transcript CG13962-RA	0.035
Rfabg	Retinoid- and fatty acid-binding glycoprotein	0.034
Tl	Toll	0.031
repo	reversed polarity	0.031
Fak56D	Focal Adhesion Kinase	0.031
Lsp1alpha	Larval serum protein 1 alpha	0.031	Fly
ird1	immune response deficient 1	0.030
Cdlc2	Cytoplasmic dynein light chain 2	0.029
spz	spatzle	0.027
CG8455	CG8455 gene product from transcript CG8455-RA	0.027
l(2)k16918	lethal (2) k16918	0.027
stai	stathmin	0.026
ena	enabled	0.025
KdelR	KDEL receptor	0.025
AttA	Attacin-A	0.023
CG6361	CG6361 gene product from transcript CG6361-RA	0.023
Pten	CG5671 gene product from transcript CG5671-RB	0.022
CYLD	cylindromatosis	0.021
Oli	Olig family	0.020
Akt1	CG4006 gene product from transcript CG4006-RA	0.020
Sr-CI	Scavenger receptor class C, type I	0.020
GNBP1	Gram-negative bacteria binding protein 1	0.020
nAcRbeta-21C	nicotinic acetylcholine receptor beta 21C	0.020
CG14225	CG14225 gene product from transcript CG14225-RA	0.020
cora	coracle	0.020
Hr96	Hormone receptor-like in 96	0.019
scf	supercoiling factor	0.019
CG33523	CG33523 gene product from transcript CG33523-RD	0.018
Lsp2	Larval serum protein 2	0.018	Fly
Lsp1beta	Larval serum protein 1 beta	0.016	Fly
CG31352	CG31352 gene product from transcript CG31352-RA	0.016
gish	gilgamesh	0.016
CG18563	CG18563 gene product from transcript CG18563-RB	0.016
Sgs1	Salivary gland secretion 1	0.015
egr	eiger	0.015
alpha-Est2	alpha-Esterase-2	0.015
rempA	reduced mechanoreceptor potential A	0.015
RhoGAP68F	CG6811 gene product from transcript CG6811-RA	0.014
CG6385	CG6385 gene product from transcript CG6385-RA	0.014
eater	CG6124 gene product from transcript CG6124-RB	0.014
PGRP-SC1a	CG14746 gene product from transcript CG14746-RA	0.014
Sdc	Syndecan	0.014
scb	scab	0.014
chic	chickadee	0.014
bip2	CG2009 gene product from transcript CG2009-RA	0.014
CG42235	CG42235 gene product from transcript CG42235-RE	0.014
CG17777	CG17777 gene product from transcript CG17777-RB	0.014
Lcp1	Larval cuticle protein 1	0.013
mts	microtubule star	0.013
Timp	Tissue inhibitor of metalloproteases	0.013
rev7	CG2948 gene product from transcript CG2948-RA	0.013
CG1092	CG1092 gene product from transcript CG1092-RA	0.013
vib	vibrator	0.013
Rab8	Rab-protein 8	0.013
Yp3	Yolk protein 3	0.013
alpha-Est5	alpha-Esterase-5	0.013
CG5999	CG5999 gene product from transcript CG5999-RB	0.013
CG8501	CG8501 gene product from transcript CG8501-RA	0.013
C1GalTA	Core 1 Galactosyltransferase A	0.013
Rho1	CG8416 gene product from transcript CG8416-RB	0.012	Fly
CG32335	CG32335 gene product from transcript CG32335-RB	0.012
Adf1	Adh transcription factor 1	0.012
nrv2	nervana 2	0.012
CG15369	CG15369 gene product from transcript CG15369-RA	0.012
Cyp4s3	CG9081 gene product from transcript CG9081-RA	0.012
Cpr49Ad	Cuticular protein 49Ad	0.012
kermit	CG11546 gene product from transcript CG11546-RB	0.012
Syx6	Syntaxin 6	0.012
Ptp52F	CG18243 gene product from transcript CG18243-RB	0.012
Spn77Ba	Serpin 77Ba	0.012
prom	prominin	0.012
CycJ	Cyclin J	0.012
cact	cactus	0.012
rok	Rho-kinase	0.012
vkg	viking	0.011
Yp1	Yolk protein 1	0.011
stumps	CG31317 gene product from transcript CG31317-RC	0.011
Myo31DF	Myosin 31DF	0.011
CG15917	CG15917 gene product from transcript CG15917-RA	0.011
sm	smooth	0.011
Rab2	Rab-protein 2	0.011
Yp2	Yolk protein 2	0.011
htt	huntingtin	0.011
CG4950	CG4950 gene product from transcript CG4950-RB	0.011
Pxn	Peroxidasin	0.011
Spase25	Spase 25-subunit	0.011
RhoGAP93B	CG3421 gene product from transcript CG3421-RA	0.011
Snp	Snipper	0.011
Fas3	Fasciclin 3	0.011
CG9911	CG9911 gene product from transcript CG9911-RD	0.011
CG9650	CG9650 gene product from transcript CG9650-RG	0.010
CG32185	CG32185 gene product from transcript CG32185-RA	0.010
l(2)k09913	lethal (2) k09913	0.010
lkb1	CG9374 gene product from transcript CG9374-RJ	0.010