IMP

Process View

Homo sapiens

25 genes annotated in human

Multi-species View

regulation of membrane permeability

GO:0090559

Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of membrane permeability"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of membrane permeability" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2	B-cell CLL/lymphoma 2	0.999	Human Mouse
BCL2L1	BCL2-like 1	0.998
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.995	Mouse
BAX	BCL2-associated X protein	0.931	Human Mouse
BAD	BCL2-associated agonist of cell death	0.871
JUN	jun proto-oncogene	0.794	Human
BAK1	BCL2-antagonist/killer 1	0.794
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.776	Human
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.739
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.566
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.555
BID	BH3 interacting domain death agonist	0.500	Mouse
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.424
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.334
PXMP2	peroxisomal membrane protein 2, 22kDa	0.324
BECN1	beclin 1, autophagy related	0.232
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.226
BIK	BCL2-interacting killer (apoptosis-inducing)	0.174
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.172	Human
TP53BP2	tumor protein p53 binding protein, 2	0.169
ATF3	activating transcription factor 3	0.159
BBC3	BCL2 binding component 3	0.136
EEF2	eukaryotic translation elongation factor 2	0.118
IER2	immediate early response 2	0.112
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.111
MAPK8	mitogen-activated protein kinase 8	0.090
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.086
VDAC1	voltage-dependent anion channel 1	0.083
FKBP8	FK506 binding protein 8, 38kDa	0.075
ACAT1	acetyl-CoA acetyltransferase 1	0.068
MAGEH1	melanoma antigen family H, 1	0.066
FOSL1	FOS-like antigen 1	0.064
SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	0.053
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.053
PLDN	pallidin homolog (mouse)	0.052
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.050
BLOC1S3	biogenesis of lysosomal organelles complex-1, subunit 3	0.046
AHCY	adenosylhomocysteinase	0.044
MUTED	muted homolog (mouse)	0.042
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.040
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.039
JUND	jun D proto-oncogene	0.038	Human
AMBRA1	autophagy/beclin-1 regulator 1	0.035
DTNBP1	dystrobrevin binding protein 1	0.033
VDAC2	voltage-dependent anion channel 2	0.031
CAMK2B	calcium/calmodulin-dependent protein kinase II beta	0.029
ZHX1	zinc fingers and homeoboxes 1	0.029
BCL2L2	BCL2-like 2	0.029	Human
C4orf14	chromosome 4 open reading frame 14	0.029
AXIN1	axin 1	0.028
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.026
PSEN2	presenilin 2 (Alzheimer disease 4)	0.026
ING2	inhibitor of growth family, member 2	0.026
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.026
OCIAD1	OCIA domain containing 1	0.025
TMEM11	transmembrane protein 11	0.025
CLU	clusterin	0.022
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.022
OXA1L	oxidase (cytochrome c) assembly 1-like	0.022
JUNB	jun B proto-oncogene	0.021	Human
ZFYVE1	zinc finger, FYVE domain containing 1	0.021
IRF2BP1	interferon regulatory factor 2 binding protein 1	0.019
ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	0.018
HUWE1	HECT, UBA and WWE domain containing 1	0.018
ZFAND5	zinc finger, AN1-type domain 5	0.018
BHLHE40	basic helix-loop-helix family, member e40	0.018
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.017
C20orf24	chromosome 20 open reading frame 24	0.016
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.016
DDIT3	DNA-damage-inducible transcript 3	0.015
SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	0.015
HADHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	0.015
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.014
SH3GLB2	SH3-domain GRB2-like endophilin B2	0.014
SNX3	sorting nexin 3	0.014
HIPK2	homeodomain interacting protein kinase 2	0.014
MAPK1	mitogen-activated protein kinase 1	0.014
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.014
PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A	0.014
PDCD6	programmed cell death 6	0.014
SPNS1	spinster homolog 1 (Drosophila)	0.013
NBR1	neighbor of BRCA1 gene 1	0.013
NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	0.013
JAK1	Janus kinase 1	0.013
GRIA4	glutamate receptor, ionotrophic, AMPA 4	0.013
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.013
PHB2	prohibitin 2	0.012
JDP2	Jun dimerization protein 2	0.012
DUSP1	dual specificity phosphatase 1	0.012
MAPK14	mitogen-activated protein kinase 14	0.012
ZDHHC17	zinc finger, DHHC-type containing 17	0.012
ERP29	endoplasmic reticulum protein 29	0.012
IL8	interleukin 8	0.012
PINK1	PTEN induced putative kinase 1	0.012
ELK1	ELK1, member of ETS oncogene family	0.012
IRF3	interferon regulatory factor 3	0.012
TSPYL4	TSPY-like 4	0.011
WDR24	WD repeat domain 24	0.011
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.011
ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	0.011
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.011
GBP2	guanylate binding protein 2, interferon-inducible	0.011
TRIB1	tribbles homolog 1 (Drosophila)	0.011
LTA4H	leukotriene A4 hydrolase	0.011
IER5	immediate early response 5	0.011
RANGAP1	Ran GTPase activating protein 1	0.011
AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1	0.010
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.010
ENO1	enolase 1, (alpha)	0.010
MEST	mesoderm specific transcript homolog (mouse)	0.010