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Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of interferon alpha production"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of interferon alpha production" (in gray)

Name	Description	Probability	Func Analog Organism
STAT1	signal transducer and activator of transcription 1, 91kDa	0.986
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.975
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.921
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.911	Human
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.852	Human
MYD88	myeloid differentiation primary response gene (88)	0.850
TBK1	TANK-binding kinase 1	0.845
CYLD	cylindromatosis (turban tumor syndrome)	0.720
TRIM21	tripartite motif containing 21	0.663
SP110	SP110 nuclear body protein	0.560
STAT2	signal transducer and activator of transcription 2, 113kDa	0.552
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.445
IRF7	interferon regulatory factor 7	0.431
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.331
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.305
DTX3L	deltex 3-like (Drosophila)	0.264
IRF3	interferon regulatory factor 3	0.254	Human Mouse
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.228
NMI	N-myc (and STAT) interactor	0.203
IRF9	interferon regulatory factor 9	0.199	Human
IFIH1	interferon induced with helicase C domain 1	0.198
IFI35	interferon-induced protein 35	0.168
MAVS	mitochondrial antiviral signaling protein	0.168
ADAR	adenosine deaminase, RNA-specific	0.166
PARP12	poly (ADP-ribose) polymerase family, member 12	0.152	Human
PARP9	poly (ADP-ribose) polymerase family, member 9	0.151
TRAF3	TNF receptor-associated factor 3	0.125
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.122
SP100	SP100 nuclear antigen	0.112
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.100
IFI44	interferon-induced protein 44	0.097
NLRC5	NLR family, CARD domain containing 5	0.094
OAS3	2'-5'-oligoadenylate synthetase 3, 100kDa	0.089
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.084
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.083
TANK	TRAF family member-associated NFKB activator	0.082
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.062
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.060
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.058
IRAK1	interleukin-1 receptor-associated kinase 1	0.053
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.051
SAMD9	sterile alpha motif domain containing 9	0.046
USP18	ubiquitin specific peptidase 18	0.045
C19orf66	chromosome 19 open reading frame 66	0.043
TRAF2	TNF receptor-associated factor 2	0.042
TRIM25	tripartite motif containing 25	0.040
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.036
BIRC3	baculoviral IAP repeat containing 3	0.034
IFI16	interferon, gamma-inducible protein 16	0.033
XAF1	XIAP associated factor 1	0.032
ISG20	interferon stimulated exonuclease gene 20kDa	0.031
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	0.030
TNRC6A	trinucleotide repeat containing 6A	0.030
HERC5	hect domain and RLD 5	0.029
APOL6	apolipoprotein L, 6	0.029
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.027
PIAS4	protein inhibitor of activated STAT, 4	0.027
AZI2	5-azacytidine induced 2	0.025
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.022
OASL	2'-5'-oligoadenylate synthetase-like	0.022
LY96	lymphocyte antigen 96	0.022
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.021
TRIM14	tripartite motif containing 14	0.021
TRIM22	tripartite motif containing 22	0.020
IRF2	interferon regulatory factor 2	0.020	Human
CHUK	conserved helix-loop-helix ubiquitous kinase	0.019	Human
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.019
DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58	0.019	Human
RTP4	receptor (chemosensory) transporter protein 4	0.019
TLR2	toll-like receptor 2	0.018
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.018
TDRD7	tudor domain containing 7	0.018
PARP14	poly (ADP-ribose) polymerase family, member 14	0.017
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.016
TICAM2	toll-like receptor adaptor molecule 2	0.016
TNRC6C	trinucleotide repeat containing 6C	0.016
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.016
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.015
PHF11	PHD finger protein 11	0.015
IRF2BP2	interferon regulatory factor 2 binding protein 2	0.015
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.015
SAMD9L	sterile alpha motif domain containing 9-like	0.014
TLR4	toll-like receptor 4	0.014	Human Mouse
ISG15	ISG15 ubiquitin-like modifier	0.014
HSPH1	heat shock 105kDa/110kDa protein 1	0.014
TRIM5	tripartite motif containing 5	0.013
IFI6	interferon, alpha-inducible protein 6	0.013
APOL3	apolipoprotein L, 3	0.013
EPSTI1	epithelial stromal interaction 1 (breast)	0.013
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.013
CXCL10	chemokine (C-X-C motif) ligand 10	0.013
TMEM173	transmembrane protein 173	0.012
CLTC	clathrin, heavy chain (Hc)	0.012
BTK	Bruton agammaglobulinemia tyrosine kinase	0.012
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.012
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.012
TLR1	toll-like receptor 1	0.012	Human
FOXO3	forkhead box O3	0.011
RSAD2	radical S-adenosyl methionine domain containing 2	0.011