IMP

Process View

Homo sapiens

21 genes annotated in human

regulation of phagocytosis

Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of phagocytosis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of phagocytosis" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.970
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.939
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.881	Human
EGFR	epidermal growth factor receptor	0.833
SYK	spleen tyrosine kinase	0.702	Mouse
GRB2	growth factor receptor-bound protein 2	0.597
PXN	paxillin	0.329
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.280
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.255
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.244	Worm
PDIA3	protein disulfide isomerase family A, member 3	0.202
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.196
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.177
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.171
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.170
FYN	FYN oncogene related to SRC, FGR, YES	0.163	Human
HCK	hemopoietic cell kinase	0.150
FN1	fibronectin 1	0.146
FHL2	four and a half LIM domains 2	0.138
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.136
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.135
LCK	lymphocyte-specific protein tyrosine kinase	0.121	Human
ENG	endoglin	0.090
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.083
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.079
UBASH3B	ubiquitin associated and SH3 domain containing B	0.072
AXL	AXL receptor tyrosine kinase	0.066	Human
ZYX	zyxin	0.062
SPRR2A	small proline-rich protein 2A	0.061
GAS6	growth arrest-specific 6	0.052
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.052
BCAR1	breast cancer anti-estrogen resistance 1	0.051
NCK1	NCK adaptor protein 1	0.051
TFF1	trefoil factor 1	0.048
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.046
THBS1	thrombospondin 1	0.045
PTK2	PTK2 protein tyrosine kinase 2	0.045	Rat
FLNA	filamin A, alpha	0.045
C1QA	complement component 1, q subcomponent, A chain	0.044	Human
C1QB	complement component 1, q subcomponent, B chain	0.036	Human
VAV1	vav 1 guanine nucleotide exchange factor	0.036
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.034
TYROBP	TYRO protein tyrosine kinase binding protein	0.032
MUC1	mucin 1, cell surface associated	0.031
CD2AP	CD2-associated protein	0.027
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.027
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.027	Human
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.026
MCFD2	multiple coagulation factor deficiency 2	0.025
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.025	Human Mouse
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.025
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.025
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.023	Human
CAV1	caveolin 1, caveolae protein, 22kDa	0.022
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.022
ADAM19	ADAM metallopeptidase domain 19	0.021
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.020
BLNK	B-cell linker	0.019
TLN1	talin 1	0.019
ALB	albumin	0.019
NCKAP1	NCK-associated protein 1	0.018
HK3	hexokinase 3 (white cell)	0.018
CFH	complement factor H	0.016
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.016	Human Worm
RIN1	Ras and Rab interactor 1	0.016
NLRC4	NLR family, CARD domain containing 4	0.016
VCL	vinculin	0.015
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.015
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.015
CD33	CD33 molecule	0.014
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.014
ITGA6	integrin, alpha 6	0.014	Human
HIPK2	homeodomain interacting protein kinase 2	0.014
EPOR	erythropoietin receptor	0.013
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.013
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.013
CCR1	chemokine (C-C motif) receptor 1	0.013
TTR	transthyretin	0.013
ITGB4	integrin, beta 4	0.013
CANX	calnexin	0.012
SH3KBP1	SH3-domain kinase binding protein 1	0.012
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.012
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.012
MLPH	melanophilin	0.012
SIGLEC7	sialic acid binding Ig-like lectin 7	0.012	Mouse
ACTN1	actinin, alpha 1	0.012
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.012
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.012
SPRY4	sprouty homolog 4 (Drosophila)	0.012
VCAM1	vascular cell adhesion molecule 1	0.012
PILRA	paired immunoglobin-like type 2 receptor alpha	0.012
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.012
VAV2	vav 2 guanine nucleotide exchange factor	0.012
PLCG1	phospholipase C, gamma 1	0.012
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.011
S100B	S100 calcium binding protein B	0.011
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.011	Mouse
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.011
SRCIN1	SRC kinase signaling inhibitor 1	0.011
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.011
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.011
PDIA4	protein disulfide isomerase family A, member 4	0.011
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.011
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.011
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.011
PTAFR	platelet-activating factor receptor	0.010