IMP

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Homo sapiens

37 genes annotated in human

monovalent inorganic cation homeostasis

Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "monovalent inorganic cation homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "monovalent inorganic cation homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2L1	BCL2-like 1	0.970	Human
BCL2	B-cell CLL/lymphoma 2	0.879
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.861
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.833	Yeast Zebrafish Fly
BAX	BCL2-associated X protein	0.707	Human
GDI2	GDP dissociation inhibitor 2	0.542
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.418
ACTN2	actinin, alpha 2	0.382
RAB5A	RAB5A, member RAS oncogene family	0.315
ATF2	activating transcription factor 2	0.228
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.196
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.167	Worm Fly
ATP6V1E1	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	0.163
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.135
PDZK1	PDZ domain containing 1	0.128
TBC1D10A	TBC1 domain family, member 10A	0.123
ATP6V1D	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D	0.120
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.119
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.115
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.102
AP1G1	adaptor-related protein complex 1, gamma 1 subunit	0.092
ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	0.092
RNR2	l-rRNA	0.087
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.084
ADRB2	adrenergic, beta-2-, receptor, surface	0.082
EEA1	early endosome antigen 1	0.076
BAK1	BCL2-antagonist/killer 1	0.072
GOLGA2	golgin A2	0.071
RNF144B	ring finger protein 144B	0.070
RAB1A	RAB1A, member RAS oncogene family	0.064
NAGK	N-acetylglucosamine kinase	0.064
ADORA2A	adenosine A2a receptor	0.060	Rat
BAD	BCL2-associated agonist of cell death	0.057
EZR	ezrin	0.056
OCRL	oculocerebrorenal syndrome of Lowe	0.055
CHP2	calcineurin B homologous protein 2	0.052
RAB6A	RAB6A, member RAS oncogene family	0.050
SPHAR	S-phase response (cyclin related)	0.049
CLCN3	chloride channel 3	0.048
ATP6V0A1	ATPase, H+ transporting, lysosomal V0 subunit a1	0.047	Human
CUL1	cullin 1	0.046
LAMP1	lysosomal-associated membrane protein 1	0.045
TYK2	tyrosine kinase 2	0.042
MFSD1	major facilitator superfamily domain containing 1	0.042
PLEKHB2	pleckstrin homology domain containing, family B (evectins) member 2	0.041
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.040
DRD2	dopamine receptor D2	0.039	Mouse
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.039
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.039
ATN1	atrophin 1	0.037
WFDC2	WAP four-disulfide core domain 2	0.036
GLP1R	glucagon-like peptide 1 receptor	0.035
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.035
ATP6AP1	ATPase, H+ transporting, lysosomal accessory protein 1	0.034	Mouse
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.033
CAV2	caveolin 2	0.033
CTSD	cathepsin D	0.032
ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	0.031
NAMPT	nicotinamide phosphoribosyltransferase	0.031
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.029	Human
ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1	0.028	Fly
ADORA1	adenosine A1 receptor	0.028	Rat
PTEN	phosphatase and tensin homolog	0.028
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.027
IRF3	interferon regulatory factor 3	0.027
P2RY1	purinergic receptor P2Y, G-protein coupled, 1	0.027
GLB1	galactosidase, beta 1	0.026
TTN	titin	0.026
MYOZ1	myozenin 1	0.025
WSB2	WD repeat and SOCS box containing 2	0.025
TMF1	TATA element modulatory factor 1	0.025
MFSD5	major facilitator superfamily domain containing 5	0.024
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.024
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.024
ARL8B	ADP-ribosylation factor-like 8B	0.024
MUC4	mucin 4, cell surface associated	0.024
SCARB2	scavenger receptor class B, member 2	0.024
GRM1	glutamate receptor, metabotropic 1	0.024
TACR1	tachykinin receptor 1	0.024	Rat
TACSTD2	tumor-associated calcium signal transducer 2	0.024
WBP2	WW domain binding protein 2	0.024
RARA	retinoic acid receptor, alpha	0.022
GDE1	glycerophosphodiester phosphodiesterase 1	0.022
FBXW2	F-box and WD repeat domain containing 2	0.022
NDRG2	NDRG family member 2	0.021
BID	BH3 interacting domain death agonist	0.021
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.021
ATM	ataxia telangiectasia mutated	0.021
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.021
EIF1B	eukaryotic translation initiation factor 1B	0.021
EPN1	epsin 1	0.021
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.021
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.021
RAI1	retinoic acid induced 1	0.021
SLC4A4	solute carrier family 4, sodium bicarbonate cotransporter, member 4	0.020
STX12	syntaxin 12	0.020
ARRB1	arrestin, beta 1	0.020
NECAB2	N-terminal EF-hand calcium binding protein 2	0.020
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.019	Human
BTRC	beta-transducin repeat containing	0.019
ARF3	ADP-ribosylation factor 3	0.019
SDCBP	syndecan binding protein (syntenin)	0.019
PICALM	phosphatidylinositol binding clathrin assembly protein	0.019
CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)	0.019
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.019
MUC13	mucin 13, cell surface associated	0.019
VDAC1	voltage-dependent anion channel 1	0.019
PSAP	prosaposin	0.018
FGB	fibrinogen beta chain	0.018
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.018
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.018
PIGR	polymeric immunoglobulin receptor	0.018
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.018
PON1	paraoxonase 1	0.018
AP1M2	adaptor-related protein complex 1, mu 2 subunit	0.018
NPY	neuropeptide Y	0.018
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.017
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.017
RPP14	ribonuclease P/MRP 14kDa subunit	0.017
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.017
PLD3	phospholipase D family, member 3	0.017
SPDEF	SAM pointed domain containing ets transcription factor	0.017
FXYD3	FXYD domain containing ion transport regulator 3	0.017
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.016	Human
ATP6V1G1	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1	0.016
DYNLT3	dynein, light chain, Tctex-type 3	0.016
RAB22A	RAB22A, member RAS oncogene family	0.016
UVRAG	UV radiation resistance associated gene	0.016
APLP2	amyloid beta (A4) precursor-like protein 2	0.016
HMG20A	high mobility group 20A	0.016
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.016
H2AFY	H2A histone family, member Y	0.016
SLC6A13	solute carrier family 6 (neurotransmitter transporter, GABA), member 13	0.016
FAM71C	family with sequence similarity 71, member C	0.016
TACR2	tachykinin receptor 2	0.016
PCDH1	protocadherin 1	0.016
AP1S1	adaptor-related protein complex 1, sigma 1 subunit	0.015
UNC45A	unc-45 homolog A (C. elegans)	0.015
ATP4A	ATPase, H+/K+ exchanging, alpha polypeptide	0.015	Human
CEACAM5	carcinoembryonic antigen-related cell adhesion molecule 5	0.015
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.015
RUFY1	RUN and FYVE domain containing 1	0.015
ACSL1	acyl-CoA synthetase long-chain family member 1	0.015
NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	0.015
USP42	ubiquitin specific peptidase 42	0.015
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.015
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.015
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.015
LMTK2	lemur tyrosine kinase 2	0.015
LDB3	LIM domain binding 3	0.015
CEACAM7	carcinoembryonic antigen-related cell adhesion molecule 7	0.015
TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)	0.015
FBXO33	F-box protein 33	0.014
ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa	0.014
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.014	Human
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.014
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.014
GPR108	G protein-coupled receptor 108	0.014
SLC13A2	solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2	0.014
EPS8L1	EPS8-like 1	0.014
ZBTB16	zinc finger and BTB domain containing 16	0.014
CTSA	cathepsin A	0.014
ATP6V1B1	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1	0.014
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.014
ZDHHC17	zinc finger, DHHC-type containing 17	0.014
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.014
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.014
GLS	glutaminase	0.013
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.013
RAB14	RAB14, member RAS oncogene family	0.013	Human Fly
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.013
TPP1	tripeptidyl peptidase I	0.013
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.013
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.013
SCN7A	sodium channel, voltage-gated, type VII, alpha	0.013
ADAM9	ADAM metallopeptidase domain 9	0.013
CDH16	cadherin 16, KSP-cadherin	0.013
ATG9A	ATG9 autophagy related 9 homolog A (S. cerevisiae)	0.013
PLEKHG6	pleckstrin homology domain containing, family G (with RhoGef domain) member 6	0.013
AQP2	aquaporin 2 (collecting duct)	0.013
HSPA13	heat shock protein 70kDa family, member 13	0.013
KAT2B	K(lysine) acetyltransferase 2B	0.013
SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1	0.013
GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)	0.013
ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	0.013
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.013
NEU1	sialidase 1 (lysosomal sialidase)	0.013
PTPRN	protein tyrosine phosphatase, receptor type, N	0.013
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.013
SIGMAR1	sigma non-opioid intracellular receptor 1	0.013
ATP4B	ATPase, H+/K+ exchanging, beta polypeptide	0.013	Human
DDN	dendrin	0.013
CORO1C	coronin, actin binding protein, 1C	0.013
TMPRSS2	transmembrane protease, serine 2	0.012	Human
TJP3	tight junction protein 3 (zona occludens 3)	0.012
MCOLN1	mucolipin 1	0.012
JUN	jun proto-oncogene	0.012
BIK	BCL2-interacting killer (apoptosis-inducing)	0.012
SLC15A1	solute carrier family 15 (oligopeptide transporter), member 1	0.012
GABRA6	gamma-aminobutyric acid (GABA) A receptor, alpha 6	0.012
ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.012
TAC1	tachykinin, precursor 1	0.012	Rat
FBXW7	F-box and WD repeat domain containing 7	0.012
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.012
GRN	granulin	0.012
LAD1	ladinin 1	0.012
EDNRA	endothelin receptor type A	0.012
KCNE1	potassium voltage-gated channel, Isk-related family, member 1	0.012
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.012
CNR1	cannabinoid receptor 1 (brain)	0.012
ABCC6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	0.012
C5orf15	chromosome 5 open reading frame 15	0.012
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.012
GFAP	glial fibrillary acidic protein	0.012
MT3	metallothionein 3	0.012
GDI1	GDP dissociation inhibitor 1	0.012
VIL1	villin 1	0.012
FAM83E	family with sequence similarity 83, member E	0.012
ATP6V1F	ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F	0.012
DAO	D-amino-acid oxidase	0.012
KNG1	kininogen 1	0.012
SYN2	synapsin II	0.012
AGTR1	angiotensin II receptor, type 1	0.012	Rat
PTPRH	protein tyrosine phosphatase, receptor type, H	0.012
TRPM3	transient receptor potential cation channel, subfamily M, member 3	0.012
GPR6	G protein-coupled receptor 6	0.012
ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.012
SPAG8	sperm associated antigen 8	0.012
DPYSL2	dihydropyrimidinase-like 2	0.011
CHRM5	cholinergic receptor, muscarinic 5	0.011
GJB1	gap junction protein, beta 1, 32kDa	0.011
FUT3	fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)	0.011
PLEKHA6	pleckstrin homology domain containing, family A member 6	0.011
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.011
RAB8B	RAB8B, member RAS oncogene family	0.011
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.011
FKBP8	FK506 binding protein 8, 38kDa	0.011
PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B	0.011
SS18	synovial sarcoma translocation, chromosome 18	0.011
SLC6A7	solute carrier family 6 (neurotransmitter transporter, L-proline), member 7	0.011
PDE4C	phosphodiesterase 4C, cAMP-specific	0.011
TP53BP2	tumor protein p53 binding protein, 2	0.011
PHKG1	phosphorylase kinase, gamma 1 (muscle)	0.011
CARHSP1	calcium regulated heat stable protein 1, 24kDa	0.011
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.011
RGN	regucalcin (senescence marker protein-30)	0.011
TMEM30B	transmembrane protein 30B	0.011
MAT1A	methionine adenosyltransferase I, alpha	0.011
PRSS23	protease, serine, 23	0.011
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.011
HIPK4	homeodomain interacting protein kinase 4	0.011
GSTA3	glutathione S-transferase alpha 3	0.011
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.011
CLDN3	claudin 3	0.011
IVL	involucrin	0.011
FZD6	frizzled homolog 6 (Drosophila)	0.011
PRLR	prolactin receptor	0.011
PNLIPRP1	pancreatic lipase-related protein 1	0.011
SCAMP2	secretory carrier membrane protein 2	0.011
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.011
EPN3	epsin 3	0.011
ANXA5	annexin A5	0.011
SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.011
RAB7A	RAB7A, member RAS oncogene family	0.011
FBXO4	F-box protein 4	0.010
MUC5B	mucin 5B, oligomeric mucus/gel-forming	0.010
TREH	trehalase (brush-border membrane glycoprotein)	0.010
LTA4H	leukotriene A4 hydrolase	0.010
GSTM4	glutathione S-transferase mu 4	0.010
MTNR1A	melatonin receptor 1A	0.010
GLA	galactosidase, alpha	0.010
ATP2C2	ATPase, Ca++ transporting, type 2C, member 2	0.010	Yeast
GABRQ	gamma-aminobutyric acid (GABA) receptor, theta	0.010
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.010
OPRK1	opioid receptor, kappa 1	0.010
FABP4	fatty acid binding protein 4, adipocyte	0.010
POU2F3	POU class 2 homeobox 3	0.010
DUSP3	dual specificity phosphatase 3	0.010
KLKB1	kallikrein B, plasma (Fletcher factor) 1	0.010
ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H	0.010
TMEM9B	TMEM9 domain family, member B	0.010
CALU	calumenin	0.010
RAB2A	RAB2A, member RAS oncogene family	0.010	Human Worm
CYP4B1	cytochrome P450, family 4, subfamily B, polypeptide 1	0.010	Human
NPTN	neuroplastin	0.010
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.010
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.010
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.010
TMC5	transmembrane channel-like 5	0.010
TMX2	thioredoxin-related transmembrane protein 2	0.010
CNGA3	cyclic nucleotide gated channel alpha 3	0.010
SLC9A2	solute carrier family 9 (sodium/hydrogen exchanger), member 2	0.010	Human Mouse Worm
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.010
CCKBR	cholecystokinin B receptor	0.010
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.010
ILVBL	ilvB (bacterial acetolactate synthase)-like	0.010
SWAP70	SWAP switching B-cell complex 70kDa subunit	0.010