IMP

Process View

Homo sapiens

4 genes annotated in human

Multi-species View

mhc class ii biosynthetic process

GO:0045342

The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "mhc class ii biosynthetic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "mhc class ii biosynthetic process" (in gray)

Name	Description	Probability	Func Analog Organism
CXCL3	chemokine (C-X-C motif) ligand 3	0.998	Human
IL8	interleukin 8	0.998
CXCL2	chemokine (C-X-C motif) ligand 2	0.997
CXCL10	chemokine (C-X-C motif) ligand 10	0.980	Human
IL4R	interleukin 4 receptor	0.900
TICAM2	toll-like receptor adaptor molecule 2	0.880
CCL20	chemokine (C-C motif) ligand 20	0.832
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.646
DPP4	dipeptidyl-peptidase 4	0.634
PF4	platelet factor 4	0.610
CXCL11	chemokine (C-X-C motif) ligand 11	0.597	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.551	Human
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.470
IL1B	interleukin 1, beta	0.420
IL6	interleukin 6 (interferon, beta 2)	0.409
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.364	Human
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.348
CCL8	chemokine (C-C motif) ligand 8	0.324
MYD88	myeloid differentiation primary response gene (88)	0.245
CXCL5	chemokine (C-X-C motif) ligand 5	0.198	Human
UBD	ubiquitin D	0.193
FOXO3	forkhead box O3	0.165
AZU1	azurocidin 1	0.158
PF4V1	platelet factor 4 variant 1	0.148	Human
S100A12	S100 calcium binding protein A12	0.105
MPO	myeloperoxidase	0.101
CCL2	chemokine (C-C motif) ligand 2	0.097
EP300	E1A binding protein p300	0.091
IL2RG	interleukin 2 receptor, gamma	0.089
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.087
CXCR3	chemokine (C-X-C motif) receptor 3	0.087
IFNG	interferon, gamma	0.086
IDO1	indoleamine 2,3-dioxygenase 1	0.085
CXCL13	chemokine (C-X-C motif) ligand 13	0.081
PRTN3	proteinase 3	0.072	Human
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.071	Human
IRS2	insulin receptor substrate 2	0.068
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.067
SELE	selectin E	0.066
IFI44	interferon-induced protein 44	0.062
CCL7	chemokine (C-C motif) ligand 7	0.060
HBA2	hemoglobin, alpha 2	0.057
CCL5	chemokine (C-C motif) ligand 5	0.057
OASL	2'-5'-oligoadenylate synthetase-like	0.055
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.055
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.053
ELANE	elastase, neutrophil expressed	0.052	Human
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.051
APOL1	apolipoprotein L, 1	0.050
RSAD2	radical S-adenosyl methionine domain containing 2	0.044
TLR2	toll-like receptor 2	0.041
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.039
LCN2	lipocalin 2	0.038
NFE2	nuclear factor (erythroid-derived 2), 45kDa	0.037
CCL4	chemokine (C-C motif) ligand 4	0.035
GFI1	growth factor independent 1 transcription repressor	0.035
MOBKL2B	MOB1, Mps One Binder kinase activator-like 2B (yeast)	0.032
EFNA1	ephrin-A1	0.032
HBD	hemoglobin, delta	0.031
TFEC	transcription factor EC	0.031
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.030
PI3	peptidase inhibitor 3, skin-derived	0.030
ALB	albumin	0.029
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.029
RPS27	ribosomal protein S27	0.028
KAT2B	K(lysine) acetyltransferase 2B	0.028
BCL2A1	BCL2-related protein A1	0.027
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.026
IFI44L	interferon-induced protein 44-like	0.025
DEFA4	defensin, alpha 4, corticostatin	0.025
RNASE3	ribonuclease, RNase A family, 3	0.024
MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	0.023
CXCR2	chemokine (C-X-C motif) receptor 2	0.023
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.023
CCL13	chemokine (C-C motif) ligand 13	0.023
IL10	interleukin 10	0.023
CXCL9	chemokine (C-X-C motif) ligand 9	0.022	Human
RGS1	regulator of G-protein signaling 1	0.022
CCL19	chemokine (C-C motif) ligand 19	0.022
CTSG	cathepsin G	0.021
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.021
TFPI2	tissue factor pathway inhibitor 2	0.021
ALAS2	aminolevulinate, delta-, synthase 2	0.021
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.021
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.020
CLEC4G	C-type lectin domain family 4, member G	0.019
POU2F2	POU class 2 homeobox 2	0.019
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.019
IFI27	interferon, alpha-inducible protein 27	0.019
GP5	glycoprotein V (platelet)	0.019
NRGN	neurogranin (protein kinase C substrate, RC3)	0.018
RAD52	RAD52 homolog (S. cerevisiae)	0.018
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.018
BPI	bactericidal/permeability-increasing protein	0.018
RRP8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	0.018
SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.017
APOL6	apolipoprotein L, 6	0.017
PTX3	pentraxin 3, long	0.017
IFIT2	interferon-induced protein with tetratricopeptide repeats 2	0.017
CCR7	chemokine (C-C motif) receptor 7	0.017
CCL22	chemokine (C-C motif) ligand 22	0.017
INHBA	inhibin, beta A	0.017
VCAM1	vascular cell adhesion molecule 1	0.017
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.016
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.016
CCL11	chemokine (C-C motif) ligand 11	0.016
HBB	hemoglobin, beta	0.016
SOD2	superoxide dismutase 2, mitochondrial	0.015
PLEK	pleckstrin	0.015
CD83	CD83 molecule	0.015
AIM2	absent in melanoma 2	0.014
VNN1	vanin 1	0.014
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.014
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.014
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.014
GBP4	guanylate binding protein 4	0.014
IRAK3	interleukin-1 receptor-associated kinase 3	0.014
EREG	epiregulin	0.014
TNF	tumor necrosis factor	0.014
KYNU	kynureninase	0.013
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.013
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.013
CLC	Charcot-Leyden crystal protein	0.013
ADAMDEC1	ADAM-like, decysin 1	0.013
TNFSF4	tumor necrosis factor (ligand) superfamily, member 4	0.013
IRAK4	interleukin-1 receptor-associated kinase 4	0.013
BMP2	bone morphogenetic protein 2	0.012
HOXA10	homeobox A10	0.012
IL18R1	interleukin 18 receptor 1	0.012
VPREB1	pre-B lymphocyte 1	0.012
PLA1A	phospholipase A1 member A	0.012
IL13RA2	interleukin 13 receptor, alpha 2	0.012
RETN	resistin	0.012
SPOP	speckle-type POZ protein	0.012
IL7	interleukin 7	0.012
IL7R	interleukin 7 receptor	0.011
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.011
S100P	S100 calcium binding protein P	0.011
IL1R2	interleukin 1 receptor, type II	0.011
ZC3H12A	zinc finger CCCH-type containing 12A	0.011
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.010
FPR3	formyl peptide receptor 3	0.010
IL1A	interleukin 1, alpha	0.010
IL11	interleukin 11	0.010
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.010
HP	haptoglobin	0.010
FOXO1	forkhead box O1	0.010