IMP

Process View

Homo sapiens

2 genes annotated in human

Multi-species View

regulation of interleukin 2 secretion

GO:1900040

Any process that modulates the frequency, rate or extent of interleukin-2 secretion.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of interleukin 2 secretion"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of interleukin 2 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.970
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.936
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.835
TRIM39	tripartite motif containing 39	0.831	Human
BCAR1	breast cancer anti-estrogen resistance 1	0.820
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.817
TRIM5	tripartite motif containing 5	0.804	Human
MED15	mediator complex subunit 15	0.781
EGFR	epidermal growth factor receptor	0.702
RIN1	Ras and Rab interactor 1	0.591
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.545
SPRR2A	small proline-rich protein 2A	0.446
TRIM21	tripartite motif containing 21	0.432	Human
ZNF263	zinc finger protein 263	0.421
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.335
RNF126	ring finger protein 126	0.320
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.307
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.263
TRIM8	tripartite motif containing 8	0.256
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.237
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.216
SP100	SP100 nuclear antigen	0.194
ZNRF1	zinc and ring finger 1	0.169
ABI2	abl-interactor 2	0.166
MUC1	mucin 1, cell surface associated	0.163
TRIM17	tripartite motif containing 17	0.154	Human
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.154
XIAP	X-linked inhibitor of apoptosis	0.138
TRIM32	tripartite motif containing 32	0.132
TRIM43	tripartite motif containing 43	0.132
MSH5	mutS homolog 5 (E. coli)	0.129
TRIM26	tripartite motif containing 26	0.128
TRIM34	tripartite motif containing 34	0.125
DAXX	death-domain associated protein	0.124
SOS1	son of sevenless homolog 1 (Drosophila)	0.116
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.112
RNF5	ring finger protein 5	0.110
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.092
MSH4	mutS homolog 4 (E. coli)	0.092
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.088
TRIM41	tripartite motif containing 41	0.072	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.068
SP110	SP110 nuclear body protein	0.068
CTSO	cathepsin O	0.068
MCOLN1	mucolipin 1	0.067
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.064
PML	promyelocytic leukemia	0.055
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.054
ZNF473	zinc finger protein 473	0.052
PRKCA	protein kinase C, alpha	0.051
SREBF1	sterol regulatory element binding transcription factor 1	0.048
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.046
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.046
TRIM35	tripartite motif containing 35	0.042
MAVS	mitochondrial antiviral signaling protein	0.042
RNF11	ring finger protein 11	0.041
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.040
PLSCR1	phospholipid scramblase 1	0.040
ARIH2	ariadne homolog 2 (Drosophila)	0.040
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.039
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.038
TRIM52	tripartite motif containing 52	0.034
HIPK2	homeodomain interacting protein kinase 2	0.034
SHANK3	SH3 and multiple ankyrin repeat domains 3	0.034
SYK	spleen tyrosine kinase	0.033
IRF9	interferon regulatory factor 9	0.031
DTX3L	deltex 3-like (Drosophila)	0.030
RNF130	ring finger protein 130	0.030
SHB	Src homology 2 domain containing adaptor protein B	0.030
TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1	0.029
PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide	0.029
RNF4	ring finger protein 4	0.028
TRIM6-TRIM34	TRIM6-TRIM34 readthrough	0.028
FAS	Fas (TNF receptor superfamily, member 6)	0.028
PLCG1	phospholipase C, gamma 1	0.027
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.026
MR1	major histocompatibility complex, class I-related	0.025
SAMD9	sterile alpha motif domain containing 9	0.025
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.025
IRF2	interferon regulatory factor 2	0.025
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.024
FADD	Fas (TNFRSF6)-associated via death domain	0.023
TRIM25	tripartite motif containing 25	0.023
MEX3B	mex-3 homolog B (C. elegans)	0.023
GIMAP2	GTPase, IMAP family member 2	0.023
PXN	paxillin	0.022
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.022
STAT5A	signal transducer and activator of transcription 5A	0.022
RAD52	RAD52 homolog (S. cerevisiae)	0.022
CHFR	checkpoint with forkhead and ring finger domains	0.022
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.021
TRIM4	tripartite motif containing 4	0.021	Human
ADAM19	ADAM metallopeptidase domain 19	0.020
TLN2	talin 2	0.020
SORBS1	sorbin and SH3 domain containing 1	0.020
PHF11	PHD finger protein 11	0.020
ELK1	ELK1, member of ETS oncogene family	0.019
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.019
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.019
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.019
BFAR	bifunctional apoptosis regulator	0.018
RNF166	ring finger protein 166	0.018
PLCD4	phospholipase C, delta 4	0.018
ZBTB8A	zinc finger and BTB domain containing 8A	0.018
MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)	0.018
RNF25	ring finger protein 25	0.018
UBTD1	ubiquitin domain containing 1	0.018
RNF10	ring finger protein 10	0.018
RNF31	ring finger protein 31	0.017
WASF2	WAS protein family, member 2	0.017
RNF185	ring finger protein 185	0.017
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.016
TRIM6	tripartite motif containing 6	0.016	Human
MKRN3	makorin ring finger protein 3	0.016
BTN3A3	butyrophilin, subfamily 3, member A3	0.016
EGF	epidermal growth factor	0.015
TP73	tumor protein p73	0.015
SOCS7	suppressor of cytokine signaling 7	0.015
ANXA1	annexin A1	0.015
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.015
IL15	interleukin 15	0.014
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.014
TDRD7	tudor domain containing 7	0.014
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.014
PHF7	PHD finger protein 7	0.014
RHAG	Rh-associated glycoprotein	0.013
UBOX5	U-box domain containing 5	0.013
ABR	active BCR-related gene	0.013
TRIM27	tripartite motif containing 27	0.013
NMI	N-myc (and STAT) interactor	0.013
ABCF1	ATP-binding cassette, sub-family F (GCN20), member 1	0.013
BTN3A2	butyrophilin, subfamily 3, member A2	0.013
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.013
BTN2A1	butyrophilin, subfamily 2, member A1	0.013
MAPK8	mitogen-activated protein kinase 8	0.013
BRAP	BRCA1 associated protein	0.012
MID1	midline 1 (Opitz/BBB syndrome)	0.012
BIRC8	baculoviral IAP repeat containing 8	0.012
TNS4	tensin 4	0.012
MOGS	mannosyl-oligosaccharide glucosidase	0.012
PTK6	PTK6 protein tyrosine kinase 6	0.012
TUBGCP4	tubulin, gamma complex associated protein 4	0.012
RNF2	ring finger protein 2	0.012
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.011
IFIH1	interferon induced with helicase C domain 1	0.011
COBRA1	cofactor of BRCA1	0.011
NFYC	nuclear transcription factor Y, gamma	0.011
FGFR1	fibroblast growth factor receptor 1	0.011
YAP1	Yes-associated protein 1	0.011
TRIM22	tripartite motif containing 22	0.011	Human
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.011
CDON	Cdon homolog (mouse)	0.010
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.010
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.010
SEC24C	SEC24 family, member C (S. cerevisiae)	0.010
ZCCHC6	zinc finger, CCHC domain containing 6	0.010
RNF111	ring finger protein 111	0.010
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.010
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	0.010
IRS4	insulin receptor substrate 4	0.010
GTF2I	general transcription factor IIi	0.010