IMP

Process View

Homo sapiens

20 genes annotated in human

endosome organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "endosome organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "endosome organization" (in gray)

Name	Description	Probability	Func Analog Organism
SNX9	sorting nexin 9	0.997	Human
DNM2	dynamin 2	0.958	Human
AKTIP	AKT interacting protein	0.905
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.891
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.830	Human
EEA1	early endosome antigen 1	0.791
ADAM15	ADAM metallopeptidase domain 15	0.774
DNM1	dynamin 1	0.690
ITSN1	intersectin 1 (SH3 domain protein)	0.678
WASL	Wiskott-Aldrich syndrome-like	0.606
MON1B	MON1 homolog B (yeast)	0.452
S100A10	S100 calcium binding protein A10	0.442
ANXA1	annexin A1	0.407	Human
APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.373
ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	0.271
SH3GL2	SH3-domain GRB2-like 2	0.242
ANKRD28	ankyrin repeat domain 28	0.240
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.213
AMPH	amphiphysin	0.213
TDP2	tyrosyl-DNA phosphodiesterase 2	0.188
RAB7A	RAB7A, member RAS oncogene family	0.169
SYNJ1	synaptojanin 1	0.158
LRRK2	leucine-rich repeat kinase 2	0.149
BECN1	beclin 1, autophagy related	0.132
CTTN	cortactin	0.122
PDCD6IP	programmed cell death 6 interacting protein	0.092
HOOK2	hook homolog 2 (Drosophila)	0.082
SDCBP	syndecan binding protein (syntenin)	0.080
KIAA1377	KIAA1377	0.078
ADAM10	ADAM metallopeptidase domain 10	0.071
MLPH	melanophilin	0.068
SNX33	sorting nexin 33	0.068
ATP6V1B2	ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2	0.066
ANXA7	annexin A7	0.060
RAB5A	RAB5A, member RAS oncogene family	0.055	Yeast Rat
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.053
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.053
CHMP1B	chromatin modifying protein 1B	0.051
SH3GL1	SH3-domain GRB2-like 1	0.039
RHOA	ras homolog gene family, member A	0.039
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.039
ANXA5	annexin A5	0.034	Human
DTX1	deltex homolog 1 (Drosophila)	0.033
ATG14	ATG14 autophagy related 14 homolog (S. cerevisiae)	0.033
UVRAG	UV radiation resistance associated gene	0.030
HOOK3	hook homolog 3 (Drosophila)	0.030
VAMP4	vesicle-associated membrane protein 4	0.030
CHMP2B	chromatin modifying protein 2B	0.029
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.029
TNK2	tyrosine kinase, non-receptor, 2	0.028
VPS24	vacuolar protein sorting 24 homolog (S. cerevisiae)	0.028
IQGAP1	IQ motif containing GTPase activating protein 1	0.028
ATP6V1D	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D	0.027
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.027
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.027
RABAC1	Rab acceptor 1 (prenylated)	0.025
CKAP4	cytoskeleton-associated protein 4	0.025
NMT2	N-myristoyltransferase 2	0.024
VIM	vimentin	0.024
AMBRA1	autophagy/beclin-1 regulator 1	0.023
ANXA2	annexin A2	0.022	Human
ITGB5	integrin, beta 5	0.022
ADAM9	ADAM metallopeptidase domain 9	0.021
ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	0.021
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.021
PIK3R4	phosphoinositide-3-kinase, regulatory subunit 4	0.021
ATP6V1E1	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	0.020
DEDD	death effector domain containing	0.020
OCRL	oculocerebrorenal syndrome of Lowe	0.019
MYO5A	myosin VA (heavy chain 12, myoxin)	0.019
EXOC8	exocyst complex component 8	0.019
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.019
VPS41	vacuolar protein sorting 41 homolog (S. cerevisiae)	0.019
TM9SF4	transmembrane 9 superfamily protein member 4	0.019
S100A11	S100 calcium binding protein A11	0.018
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.018
TMSB10	thymosin beta 10	0.018
RAB22A	RAB22A, member RAS oncogene family	0.017
DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	0.016
SYTL4	synaptotagmin-like 4	0.016
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.016
NOSTRIN	nitric oxide synthase trafficker	0.015
SNAP25	synaptosomal-associated protein, 25kDa	0.015
RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.015
CLK2	CDC-like kinase 2	0.015
CHIC2	cysteine-rich hydrophobic domain 2	0.015
GPBP1L1	GC-rich promoter binding protein 1-like 1	0.014
CAB39	calcium binding protein 39	0.014
MAP2K4	mitogen-activated protein kinase kinase 4	0.014
PPP6R3	protein phosphatase 6, regulatory subunit 3	0.014
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.014
MYL12B	myosin, light chain 12B, regulatory	0.014
RAB14	RAB14, member RAS oncogene family	0.014
MED12	mediator complex subunit 12	0.014
EMP3	epithelial membrane protein 3	0.014
KIAA1468	KIAA1468	0.014
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.013
REEP6	receptor accessory protein 6	0.013
MEAF6	MYST/Esa1-associated factor 6	0.013
TGFBI	transforming growth factor, beta-induced, 68kDa	0.013
STX12	syntaxin 12	0.013
USP20	ubiquitin specific peptidase 20	0.013
KRT15	keratin 15	0.012
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.012	Fly
ARRB2	arrestin, beta 2	0.012
VCL	vinculin	0.012
MYOF	myoferlin	0.012
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.012
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.012
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.012
LARP1	La ribonucleoprotein domain family, member 1	0.012
DUSP23	dual specificity phosphatase 23	0.012
CAPN7	calpain 7	0.012
NRBF2	nuclear receptor binding factor 2	0.012
HOOK1	hook homolog 1 (Drosophila)	0.011
ACAP2	ArfGAP with coiled-coil, ankyrin repeat and PH domains 2	0.011
MARK2	MAP/microtubule affinity-regulating kinase 2	0.011
BIRC6	baculoviral IAP repeat containing 6	0.011
VIPAR	VPS33B interacting protein, apical-basolateral polarity regulator	0.011
BLNK	B-cell linker	0.011
SLC25A13	solute carrier family 25, member 13 (citrin)	0.011
SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5	0.011
SH3KBP1	SH3-domain kinase binding protein 1	0.011
LGALS1	lectin, galactoside-binding, soluble, 1	0.011
RAB11FIP3	RAB11 family interacting protein 3 (class II)	0.011
ZNF217	zinc finger protein 217	0.011
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.011
PI4KB	phosphatidylinositol 4-kinase, catalytic, beta	0.011
MYO1E	myosin IE	0.010
NPTN	neuroplastin	0.010
ACTG1	actin, gamma 1	0.010
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.010