IMP
Process View
negative regulation of alpha beta t cell proliferation
Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation.
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of alpha beta t cell proliferation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CCR5 | chemokine (C-C motif) receptor 5 | 0.999 | ||
| CCL4 | chemokine (C-C motif) ligand 4 | 0.996 | Human | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.969 | Human | |
| IL8 | interleukin 8 | 0.962 | ||
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.917 | ||
| CCL5 | chemokine (C-C motif) ligand 5 | 0.913 | Human | |
| IL1B | interleukin 1, beta | 0.887 | ||
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.866 | ||
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.826 | ||
| IDE | insulin-degrading enzyme | 0.812 | ||
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.767 | ||
| DPP4 | dipeptidyl-peptidase 4 | 0.760 | ||
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.711 | ||
| IL6 | interleukin 6 (interferon, beta 2) | 0.664 | ||
| ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.660 | ||
| DTX1 | deltex homolog 1 (Drosophila) | 0.655 | ||
| TRAF1 | TNF receptor-associated factor 1 | 0.634 | ||
| CCL22 | chemokine (C-C motif) ligand 22 | 0.625 | Human | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.604 | Human | |
| TRAF5 | TNF receptor-associated factor 5 | 0.563 | ||
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.555 | ||
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | 0.550 | ||
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.531 | ||
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.530 | ||
| CCR7 | chemokine (C-C motif) receptor 7 | 0.527 | ||
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.522 | ||
| ICAM1 | intercellular adhesion molecule 1 | 0.449 | ||
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.438 | Human | |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.422 | ||
| CCL3 | chemokine (C-C motif) ligand 3 | 0.421 | Human | |
| TNF | tumor necrosis factor | 0.421 | ||
| SNX9 | sorting nexin 9 | 0.370 | ||
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.352 | ||
| SNX18 | sorting nexin 18 | 0.299 | ||
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.270 | ||
| CD83 | CD83 molecule | 0.268 | ||
| IFNG | interferon, gamma | 0.250 | ||
| CCR4 | chemokine (C-C motif) receptor 4 | 0.239 | ||
| CCL7 | chemokine (C-C motif) ligand 7 | 0.232 | Human | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.218 | Human | |
| IL10 | interleukin 10 | 0.203 | ||
| DNM2 | dynamin 2 | 0.197 | ||
| CCL11 | chemokine (C-C motif) ligand 11 | 0.173 | Human | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.150 | ||
| RGS1 | regulator of G-protein signaling 1 | 0.147 | ||
| CCR1 | chemokine (C-C motif) receptor 1 | 0.147 | ||
| DNM1 | dynamin 1 | 0.140 | ||
| TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.139 | ||
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.133 | ||
| CCL20 | chemokine (C-C motif) ligand 20 | 0.129 | Human | |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.123 | ||
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.112 | ||
| SELE | selectin E | 0.109 | ||
| BLNK | B-cell linker | 0.106 | ||
| NKG7 | natural killer cell group 7 sequence | 0.099 | ||
| CBLC | Cas-Br-M (murine) ecotropic retroviral transforming sequence c | 0.093 | ||
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.082 | ||
| IL7R | interleukin 7 receptor | 0.079 | ||
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.079 | ||
| CCL17 | chemokine (C-C motif) ligand 17 | 0.076 | Human | |
| WASL | Wiskott-Aldrich syndrome-like | 0.074 | ||
| CCL19 | chemokine (C-C motif) ligand 19 | 0.071 | Human | |
| IL2RB | interleukin 2 receptor, beta | 0.071 | ||
| BCL2A1 | BCL2-related protein A1 | 0.070 | ||
| IL1RN | interleukin 1 receptor antagonist | 0.070 | ||
| BIRC3 | baculoviral IAP repeat containing 3 | 0.068 | ||
| SNX33 | sorting nexin 33 | 0.063 | ||
| ZBTB48 | zinc finger and BTB domain containing 48 | 0.060 | ||
| CH25H | cholesterol 25-hydroxylase | 0.060 | ||
| EBI3 | Epstein-Barr virus induced 3 | 0.059 | ||
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.058 | ||
| TRAF2 | TNF receptor-associated factor 2 | 0.056 | ||
| SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.054 | ||
| TP73 | tumor protein p73 | 0.051 | ||
| VCAM1 | vascular cell adhesion molecule 1 | 0.047 | ||
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.043 | ||
| LAMP3 | lysosomal-associated membrane protein 3 | 0.042 | ||
| UBD | ubiquitin D | 0.041 | ||
| ADAM15 | ADAM metallopeptidase domain 15 | 0.038 | ||
| CCL21 | chemokine (C-C motif) ligand 21 | 0.038 | ||
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.038 | ||
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.037 | ||
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.037 | ||
| CD80 | CD80 molecule | 0.036 | ||
| CCR3 | chemokine (C-C motif) receptor 3 | 0.035 | ||
| FPR3 | formyl peptide receptor 3 | 0.035 | ||
| IL1R2 | interleukin 1 receptor, type II | 0.035 | ||
| DARC | Duffy blood group, chemokine receptor | 0.034 | ||
| IL32 | interleukin 32 | 0.034 | ||
| IRF4 | interferon regulatory factor 4 | 0.034 | ||
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.034 | ||
| CD69 | CD69 molecule | 0.034 | ||
| IL10RA | interleukin 10 receptor, alpha | 0.033 | ||
| IL1A | interleukin 1, alpha | 0.033 | ||
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.032 | ||
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.032 | ||
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.032 | ||
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.031 | ||
| MSC | musculin | 0.030 | ||
| PI3 | peptidase inhibitor 3, skin-derived | 0.030 | ||
| CCRL2 | chemokine (C-C motif) receptor-like 2 | 0.029 | ||
| IL21R | interleukin 21 receptor | 0.028 | ||
| PLEK | pleckstrin | 0.027 | ||
| SRGN | serglycin | 0.027 | ||
| ADAMDEC1 | ADAM-like, decysin 1 | 0.027 | ||
| IL2RG | interleukin 2 receptor, gamma | 0.027 | ||
| INHBA | inhibin, beta A | 0.027 | ||
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.027 | ||
| IL2RA | interleukin 2 receptor, alpha | 0.026 | ||
| SLAMF7 | SLAM family member 7 | 0.026 | ||
| CTSW | cathepsin W | 0.026 | ||
| CTTN | cortactin | 0.026 | ||
| RGS16 | regulator of G-protein signaling 16 | 0.025 | ||
| STAT4 | signal transducer and activator of transcription 4 | 0.025 | ||
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.025 | ||
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.024 | ||
| LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.024 | ||
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.024 | ||
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.023 | ||
| CSF1 | colony stimulating factor 1 (macrophage) | 0.023 | ||
| AQP9 | aquaporin 9 | 0.023 | ||
| IL18RAP | interleukin 18 receptor accessory protein | 0.022 | ||
| IL3 | interleukin 3 (colony-stimulating factor, multiple) | 0.022 | ||
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.022 | ||
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.022 | ||
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.021 | ||
| PDCD6IP | programmed cell death 6 interacting protein | 0.021 | ||
| OSMR | oncostatin M receptor | 0.020 | ||
| STAT5A | signal transducer and activator of transcription 5A | 0.020 | ||
| XCL1 | chemokine (C motif) ligand 1 | 0.019 | ||
| MMP10 | matrix metallopeptidase 10 (stromelysin 2) | 0.019 | ||
| BATF | basic leucine zipper transcription factor, ATF-like | 0.019 | ||
| APOC1 | apolipoprotein C-I | 0.019 | ||
| CCL23 | chemokine (C-C motif) ligand 23 | 0.019 | Human | |
| CD160 | CD160 molecule | 0.019 | ||
| IL13 | interleukin 13 | 0.019 | ||
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.018 | ||
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.018 | ||
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 | 0.018 | ||
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.018 | ||
| SH3GL2 | SH3-domain GRB2-like 2 | 0.018 | ||
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.018 | ||
| GNLY | granulysin | 0.018 | ||
| HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.018 | ||
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 | 0.018 | ||
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.017 | ||
| SLAMF8 | SLAM family member 8 | 0.017 | ||
| CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.015 | ||
| MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.015 | ||
| IER3 | immediate early response 3 | 0.015 | ||
| SYNJ1 | synaptojanin 1 | 0.015 | ||
| GPR109B | G protein-coupled receptor 109B | 0.015 | ||
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.015 | ||
| SCARF1 | scavenger receptor class F, member 1 | 0.015 | ||
| A2M | alpha-2-macroglobulin | 0.015 | ||
| C5AR1 | complement component 5a receptor 1 | 0.015 | ||
| ARRB1 | arrestin, beta 1 | 0.015 | ||
| CD209 | CD209 molecule | 0.014 | ||
| DEDD | death effector domain containing | 0.014 | ||
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.014 | ||
| LRRC32 | leucine rich repeat containing 32 | 0.014 | ||
| LAG3 | lymphocyte-activation gene 3 | 0.014 | ||
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.014 | ||
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.014 | ||
| IL11 | interleukin 11 | 0.014 | ||
| TM7SF4 | transmembrane 7 superfamily member 4 | 0.014 | ||
| IL4 | interleukin 4 | 0.014 | ||
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.014 | ||
| IFNB1 | interferon, beta 1, fibroblast | 0.014 | ||
| WDR73 | WD repeat domain 73 | 0.013 | ||
| XCL2 | chemokine (C motif) ligand 2 | 0.013 | Human | |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.013 | ||
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.013 | ||
| TNK2 | tyrosine kinase, non-receptor, 2 | 0.013 | ||
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.013 | ||
| G0S2 | G0/G1switch 2 | 0.013 | ||
| IL1F5 | interleukin 1 family, member 5 (delta) | 0.013 | ||
| CSF3 | colony stimulating factor 3 (granulocyte) | 0.012 | ||
| CD40LG | CD40 ligand | 0.012 | ||
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.012 | ||
| LILRB5 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 | 0.012 | ||
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.012 | ||
| GPR84 | G protein-coupled receptor 84 | 0.012 | ||
| CCBP2 | chemokine binding protein 2 | 0.012 | ||
| RNF11 | ring finger protein 11 | 0.012 | ||
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.012 | ||
| STAMBP | STAM binding protein | 0.012 | ||
| SOD2 | superoxide dismutase 2, mitochondrial | 0.012 | ||
| IL12RB1 | interleukin 12 receptor, beta 1 | 0.012 | ||
| TLR2 | toll-like receptor 2 | 0.011 | ||
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) | 0.011 | ||
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.011 | ||
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 0.011 | ||
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.011 | ||
| CCL1 | chemokine (C-C motif) ligand 1 | 0.011 | Human | |
| IL1F9 | interleukin 1 family, member 9 | 0.011 | ||
| IL18R1 | interleukin 18 receptor 1 | 0.011 | ||
| IL5 | interleukin 5 (colony-stimulating factor, eosinophil) | 0.011 | ||
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.011 | ||
| NLRP3 | NLR family, pyrin domain containing 3 | 0.011 | ||
| DUSP2 | dual specificity phosphatase 2 | 0.011 | ||
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.011 | ||
| PLAUR | plasminogen activator, urokinase receptor | 0.011 | ||
| WWOX | WW domain containing oxidoreductase | 0.011 | ||
| IL4I1 | interleukin 4 induced 1 | 0.011 | ||
| CD1B | CD1b molecule | 0.011 | ||
| BTLA | B and T lymphocyte associated | 0.011 | ||
| BDKRB1 | bradykinin receptor B1 | 0.011 | ||
| GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 0.011 | ||
| CCDC127 | coiled-coil domain containing 127 | 0.011 | ||
| TIFA | TRAF-interacting protein with forkhead-associated domain | 0.010 | ||
| MMP3 | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 0.010 | ||
| PDCD1LG2 | programmed cell death 1 ligand 2 | 0.010 | ||
| KYNU | kynureninase | 0.010 | ||
| CD2 | CD2 molecule | 0.010 | ||
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.010 | ||
| EGR2 | early growth response 2 | 0.010 |