IMP

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Homo sapiens

3 genes annotated in human

Multi-species View

positive regulation of humoral immune response

GO:0002922

Any process that activates or increases the frequency, rate, or extent of a humoral immune response.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of humoral immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of humoral immune response" (in gray)

Name	Description	Probability	Func Analog Organism
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	1.000
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	1.000	Fly
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	1.000	Fly
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	1.000	Fly
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.999	Fly
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.993
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.985	Fly
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.977	Fly
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.966	Fly
CHUK	conserved helix-loop-helix ubiquitous kinase	0.909	Fly
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.888
BCL3	B-cell CLL/lymphoma 3	0.767	Fly
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.705	Fly
SOX10	SRY (sex determining region Y)-box 10	0.700
PAX3	paired box 3	0.609
TNIP2	TNFAIP3 interacting protein 2	0.558
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.545	Fly
NLRC4	NLR family, CARD domain containing 4	0.468
RIPK2	receptor-interacting serine-threonine kinase 2	0.457
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.439
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.404
CD22	CD22 molecule	0.289
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.209
CFH	complement factor H	0.145
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.144
IRAK2	interleukin-1 receptor-associated kinase 2	0.124
IRAK1	interleukin-1 receptor-associated kinase 1	0.088
BTRC	beta-transducin repeat containing	0.077
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.076
HLA-DMB	major histocompatibility complex, class II, DM beta	0.071
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.066
CFI	complement factor I	0.065
CD247	CD247 molecule	0.064
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.064
PYCARD	PYD and CARD domain containing	0.061
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.059
ELF4	E74-like factor 4 (ets domain transcription factor)	0.055
HLA-DRB1	major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 1	0.054
TLR2	toll-like receptor 2	0.048
IRAK4	interleukin-1 receptor-associated kinase 4	0.044
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.044
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.036
ZC3H12A	zinc finger CCCH-type containing 12A	0.036
FKBP5	FK506 binding protein 5	0.035
CFB	complement factor B	0.035
GBP2	guanylate binding protein 2, interferon-inducible	0.035
CARD16	caspase recruitment domain family, member 16	0.034
SETD7	SET domain containing (lysine methyltransferase) 7	0.032
IL18	interleukin 18 (interferon-gamma-inducing factor)	0.030
C1R	complement component 1, r subcomponent	0.029
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.029
IFI16	interferon, gamma-inducible protein 16	0.029
CHD1	chromodomain helicase DNA binding protein 1	0.028
NLRC5	NLR family, CARD domain containing 5	0.026
SOCS1	suppressor of cytokine signaling 1	0.025
IRAK3	interleukin-1 receptor-associated kinase 3	0.025
MEOX2	mesenchyme homeobox 2	0.024
HNF1A	HNF1 homeobox A	0.024
SOX21	SRY (sex determining region Y)-box 21	0.023
NCOA3	nuclear receptor coactivator 3	0.023
RAI1	retinoic acid induced 1	0.022
POU3F3	POU class 3 homeobox 3	0.022	Fly
SQRDL	sulfide quinone reductase-like (yeast)	0.022
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.022
TLR4	toll-like receptor 4	0.021
STAP2	signal transducing adaptor family member 2	0.021
CD14	CD14 molecule	0.020
EP300	E1A binding protein p300	0.020
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.020
CFLAR	CASP8 and FADD-like apoptosis regulator	0.019
DOCK8	dedicator of cytokinesis 8	0.019
KYNU	kynureninase	0.018
MAPK8	mitogen-activated protein kinase 8	0.018
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.018
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.018
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.017
TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b	0.017
CARD6	caspase recruitment domain family, member 6	0.017
LBX1	ladybird homeobox 1	0.017
SOX1	SRY (sex determining region Y)-box 1	0.016
CCL19	chemokine (C-C motif) ligand 19	0.016
LY96	lymphocyte antigen 96	0.016
TRAF6	TNF receptor-associated factor 6	0.016
SFRP5	secreted frizzled-related protein 5	0.016
ICAM1	intercellular adhesion molecule 1	0.016
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.015
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.015
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.015
LGALS1	lectin, galactoside-binding, soluble, 1	0.015
CLEC2B	C-type lectin domain family 2, member B	0.014
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.014
POU3F2	POU class 3 homeobox 2	0.014	Fly
NOVA2	neuro-oncological ventral antigen 2	0.014
PELI3	pellino homolog 3 (Drosophila)	0.014
SIRT6	sirtuin 6	0.014
NMI	N-myc (and STAT) interactor	0.014
CFHR1	complement factor H-related 1	0.014
RAX	retina and anterior neural fold homeobox	0.013
IRF1	interferon regulatory factor 1	0.013
TLR1	toll-like receptor 1	0.013
IL1B	interleukin 1, beta	0.013
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.013
MLKL	mixed lineage kinase domain-like	0.013
FUT6	fucosyltransferase 6 (alpha (1,3) fucosyltransferase)	0.013
SH2D2A	SH2 domain containing 2A	0.013
ZP2	zona pellucida glycoprotein 2 (sperm receptor)	0.012	Human
CDX1	caudal type homeobox 1	0.012	Fly
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.012
FRZB	frizzled-related protein	0.012
PAX7	paired box 7	0.012
TBP	TATA box binding protein	0.012
SOX11	SRY (sex determining region Y)-box 11	0.012
FOXB1	forkhead box B1	0.012
CTSS	cathepsin S	0.012
IL2RB	interleukin 2 receptor, beta	0.012
NLK	nemo-like kinase	0.012
EVI2A	ecotropic viral integration site 2A	0.011
IL10RB	interleukin 10 receptor, beta	0.011
ADAM15	ADAM metallopeptidase domain 15	0.011
IRF4	interferon regulatory factor 4	0.011
CALCA	calcitonin-related polypeptide alpha	0.011
PAX6	paired box 6	0.011
POU3F4	POU class 3 homeobox 4	0.011	Fly
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.011
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.011
PLSCR1	phospholipid scramblase 1	0.011
SH2D1A	SH2 domain containing 1A	0.011
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.011
IL1A	interleukin 1, alpha	0.010
NOTCH1	notch 1	0.010
NTSR2	neurotensin receptor 2	0.010
BCL2A1	BCL2-related protein A1	0.010
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.010
GLRX	glutaredoxin (thioltransferase)	0.010
BTN3A2	butyrophilin, subfamily 3, member A2	0.010
CCR6	chemokine (C-C motif) receptor 6	0.010
CREBBP	CREB binding protein	0.010
IL21R	interleukin 21 receptor	0.010
BIRC3	baculoviral IAP repeat containing 3	0.010
SLK	STE20-like kinase	0.010