IMP

Process View

Homo sapiens

3 genes annotated in human

gamma delta t cell activation

The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "gamma delta t cell activation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "gamma delta t cell activation" (in gray)

Name	Description	Probability	Func Analog Organism
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.997
PILRA	paired immunoglobin-like type 2 receptor alpha	0.975
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.971
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.912
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.889	Human
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.695
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.657
INSR	insulin receptor	0.494
CD22	CD22 molecule	0.450
EPOR	erythropoietin receptor	0.401
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.316	Human
CSK	c-src tyrosine kinase	0.263
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.261	Human
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.237
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.234
STAP2	signal transducing adaptor family member 2	0.188
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.164
IL2RB	interleukin 2 receptor, beta	0.163
GFI1B	growth factor independent 1B transcription repressor	0.159
SH2D2A	SH2 domain containing 2A	0.151
CD33	CD33 molecule	0.151
LGALS3	lectin, galactoside-binding, soluble, 3	0.146
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.146
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.142
PTAFR	platelet-activating factor receptor	0.142
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.127
SH3BP2	SH3-domain binding protein 2	0.120
PECAM1	platelet/endothelial cell adhesion molecule	0.106
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.098	Human
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.091
CTBP2	C-terminal binding protein 2	0.090
PRKCQ	protein kinase C, theta	0.086
LCK	lymphocyte-specific protein tyrosine kinase	0.080	Mouse
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.076
BLNK	B-cell linker	0.068
UBASH3B	ubiquitin associated and SH3 domain containing B	0.065
HK3	hexokinase 3 (white cell)	0.064
CD247	CD247 molecule	0.057
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.050
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.050
SMAD7	SMAD family member 7	0.049
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.045
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.043	Human
SIRPB1	signal-regulatory protein beta 1	0.040
SIGLEC10	sialic acid binding Ig-like lectin 10	0.032
AOAH	acyloxyacyl hydrolase (neutrophil)	0.032
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.031
SIGLEC7	sialic acid binding Ig-like lectin 7	0.029
NMI	N-myc (and STAT) interactor	0.029
JAK2	Janus kinase 2	0.028
TYMP	thymidine phosphorylase	0.027
NOTCH3	notch 3	0.026
AIF1	allograft inflammatory factor 1	0.026
CD72	CD72 molecule	0.026
LAT	linker for activation of T cells	0.025
VAV1	vav 1 guanine nucleotide exchange factor	0.025
NOD2	nucleotide-binding oligomerization domain containing 2	0.025
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.025
CD300A	CD300a molecule	0.025
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.025	Human
CD48	CD48 molecule	0.025
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.024
AQP9	aquaporin 9	0.023
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.023
NLRP3	NLR family, pyrin domain containing 3	0.022
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.022
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.021
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.021
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.021
CD1D	CD1d molecule	0.021
ATN1	atrophin 1	0.021
EGR2	early growth response 2	0.021
TLR8	toll-like receptor 8	0.021
SPRY4	sprouty homolog 4 (Drosophila)	0.020
HCK	hemopoietic cell kinase	0.020
SIRPA	signal-regulatory protein alpha	0.018
FPR2	formyl peptide receptor 2	0.018
GHR	growth hormone receptor	0.018
MICA	MHC class I polypeptide-related sequence A	0.018
TREM1	triggering receptor expressed on myeloid cells 1	0.018
CAV1	caveolin 1, caveolae protein, 22kDa	0.017
CD4	CD4 molecule	0.017
CCR1	chemokine (C-C motif) receptor 1	0.017
VSIG4	V-set and immunoglobulin domain containing 4	0.017
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.017
LTBP4	latent transforming growth factor beta binding protein 4	0.016
IL4R	interleukin 4 receptor	0.016
BTK	Bruton agammaglobulinemia tyrosine kinase	0.015
MICB	MHC class I polypeptide-related sequence B	0.015
VNN2	vanin 2	0.015
CD86	CD86 molecule	0.015
PLEK	pleckstrin	0.014
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.014
CD52	CD52 molecule	0.014
CD38	CD38 molecule	0.014
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.014
MYH14	myosin, heavy chain 14, non-muscle	0.013
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.013
FYB	FYN binding protein	0.013
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.013
MARCO	macrophage receptor with collagenous structure	0.013
EGR1	early growth response 1	0.013
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.013
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.013
CMKLR1	chemokine-like receptor 1	0.013
NOTCH1	notch 1	0.013
LRMP	lymphoid-restricted membrane protein	0.013
LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.013	Human
MEGF6	multiple EGF-like-domains 6	0.012
GRIP1	glutamate receptor interacting protein 1	0.012
DMPK	dystrophia myotonica-protein kinase	0.012
CD163	CD163 molecule	0.012
TRIP6	thyroid hormone receptor interactor 6	0.012
SKAP1	src kinase associated phosphoprotein 1	0.012
IRS1	insulin receptor substrate 1	0.012
PRTFDC1	phosphoribosyl transferase domain containing 1	0.012
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.012
SIGLEC9	sialic acid binding Ig-like lectin 9	0.012
SLA	Src-like-adaptor	0.012
ADAM15	ADAM metallopeptidase domain 15	0.011
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.011
CD84	CD84 molecule	0.011
IGSF6	immunoglobulin superfamily, member 6	0.011
CD300C	CD300c molecule	0.011
AGRN	agrin	0.011
TXNDC11	thioredoxin domain containing 11	0.011
SH2D1A	SH2 domain containing 1A	0.011
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.011
CRIP2	cysteine-rich protein 2	0.011
PTPRC	protein tyrosine phosphatase, receptor type, C	0.011	Mouse
LENG8	leukocyte receptor cluster (LRC) member 8	0.011
TYK2	tyrosine kinase 2	0.011
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.011
DLG1	discs, large homolog 1 (Drosophila)	0.011
PRMT2	protein arginine methyltransferase 2	0.011
TRAT1	T cell receptor associated transmembrane adaptor 1	0.010
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.010
FOLR3	folate receptor 3 (gamma)	0.010
FGB	fibrinogen beta chain	0.010
MNDA	myeloid cell nuclear differentiation antigen	0.010
NELL2	NEL-like 2 (chicken)	0.010
MTA2	metastasis associated 1 family, member 2	0.010
EXT2	exostosin 2	0.010
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.010