IMP

Process View

Mus musculus

17 genes annotated in mouse

antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii

The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii" (in gray)

Name	Description	Probability	Func Analog Organism
H2-Aa	histocompatibility 2, class II antigen A, alpha	1.000
H2-Eb1	histocompatibility 2, class II antigen E beta	0.999
H2-DMa	histocompatibility 2, class II, locus DMa	0.996
Cd74	CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)	0.962
H2-DMb2	histocompatibility 2, class II, locus Mb2	0.952
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.588
Cd22	CD22 antigen	0.551
Lyz2	lysozyme 2	0.550
Cd19	CD19 antigen	0.505
Cd79a	CD79A antigen (immunoglobulin-associated alpha)	0.391
Ciita	class II transactivator	0.383
Cd40	CD40 antigen	0.338
Ptprc	protein tyrosine phosphatase, receptor type, C	0.331
C1qa	complement component 1, q subcomponent, alpha polypeptide	0.259
Mavs	mitochondrial antiviral signaling protein	0.218
Tcra	T-cell receptor alpha chain	0.212
Aif1	allograft inflammatory factor 1	0.189
C1qc	complement component 1, q subcomponent, C chain	0.144
Ms4a1	membrane-spanning 4-domains, subfamily A, member 1	0.132
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.127
Lat	linker for activation of T cells	0.107
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.097
Ly86	lymphocyte antigen 86	0.095
C1qb	complement component 1, q subcomponent, beta polypeptide	0.072
Birc3	baculoviral IAP repeat-containing 3	0.068
Agtr1a	angiotensin II receptor, type 1a	0.068
Ctsb	cathepsin B	0.061
Fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.058
Tnfrsf13c	tumor necrosis factor receptor superfamily, member 13c	0.054
Traf6	TNF receptor-associated factor 6	0.051
Il2rg	interleukin 2 receptor, gamma chain	0.048
Cd86	CD86 antigen	0.043
Lck	lymphocyte protein tyrosine kinase	0.040
Ccr7	chemokine (C-C motif) receptor 7	0.039
Il7r	interleukin 7 receptor	0.034
Spib	Spi-B transcription factor (Spi-1/PU.1 related)	0.034
Ptgs2	prostaglandin-endoperoxide synthase 2	0.032
Ptprcap	protein tyrosine phosphatase, receptor type, C polypeptide-associated protein	0.030
Klrd1	killer cell lectin-like receptor, subfamily D, member 1	0.030
H2-Oa	histocompatibility 2, O region alpha locus	0.030
Cybb	cytochrome b-245, beta polypeptide	0.029
Clec4n	C-type lectin domain family 4, member n	0.029
Cxcl9	chemokine (C-X-C motif) ligand 9	0.028
Emr1	EGF-like module containing, mucin-like, hormone receptor-like sequence 1	0.027
Irf8	interferon regulatory factor 8	0.026
H2-Ob	histocompatibility 2, O region beta locus	0.026	Mouse
Ccr1	chemokine (C-C motif) receptor 1	0.026
Traf3ip2	TRAF3 interacting protein 2	0.025
Ncf1	neutrophil cytosolic factor 1	0.025
Ptpn22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.024
Blk	B lymphoid kinase	0.024
Napsa	napsin A aspartic peptidase	0.023	Mouse
Tgfb1	transforming growth factor, beta 1	0.023
Cd79b	CD79B antigen	0.023
Map3k8	mitogen-activated protein kinase kinase kinase 8	0.022
Lamp1	lysosomal-associated membrane protein 1	0.022
Lyz1	lysozyme 1	0.021
Psap	prosaposin	0.021
Itgae	integrin alpha E, epithelial-associated	0.020
Cd2	CD2 antigen	0.020
Tifa	TRAF-interacting protein with forkhead-associated domain	0.018
Ly6d	lymphocyte antigen 6 complex, locus D	0.018
Fgd2	FYVE, RhoGEF and PH domain containing 2	0.018
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.018
Itgax	integrin alpha X	0.017
Ly9	lymphocyte antigen 9	0.017
Pld4	phospholipase D family, member 4	0.016
Cd72	CD72 antigen	0.016
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.016
Ikzf1	IKAROS family zinc finger 1	0.015
Unc93b1	unc-93 homolog B1 (C. elegans)	0.015
Fcgr3	Fc receptor, IgG, low affinity III	0.015	Mouse
Cd83	CD83 antigen	0.015
Irf5	interferon regulatory factor 5	0.015
Mdm2	transformed mouse 3T3 cell double minute 2	0.015
Ccl5	chemokine (C-C motif) ligand 5	0.015
Hck	hemopoietic cell kinase	0.015
Tbxas1	thromboxane A synthase 1, platelet	0.014
Cd3g	CD3 antigen, gamma polypeptide	0.014
Nr3c2	nuclear receptor subfamily 3, group C, member 2	0.014
Gzma	granzyme A	0.013
Tnfrsf4	tumor necrosis factor receptor superfamily, member 4	0.012
Plbd1	phospholipase B domain containing 1	0.012
Slc11a1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.011
Irak3	interleukin-1 receptor-associated kinase 3	0.011
Il15	interleukin 15	0.011
Slamf9	SLAM family member 9	0.011
Lilrb3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.011
Stk11	serine/threonine kinase 11	0.011
Glis2	GLIS family zinc finger 2	0.011
Umod	uromodulin	0.011
Smad3	MAD homolog 3 (Drosophila)	0.011
Tnip1	TNFAIP3 interacting protein 1	0.011
Rnase6	ribonuclease, RNase A family, 6	0.011
Tlr7	toll-like receptor 7	0.011
Irf4	interferon regulatory factor 4	0.011
Cd48	CD48 antigen	0.010
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.010
Cd180	CD180 antigen	0.010
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.010
Bank1	B-cell scaffold protein with ankyrin repeats 1	0.010
Nup62-il4i1	Nup62-Il4i1 protein	0.010