IMP

Process View

Mus musculus

13 genes annotated in mouse

regulation of intrinsic apoptotic signaling pathway by p53 class mediator

GO:1902253

Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in mouse Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of intrinsic apoptotic signaling pathway by p53 class mediator"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of intrinsic apoptotic signaling pathway by p53 class mediator" (in gray)

Name	Description	Probability	Func Analog Organism
Lepr	leptin receptor	0.847
Ren1	renin 1 structural	0.751
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.739
Ptgs2	prostaglandin-endoperoxide synthase 2	0.574
Pten	phosphatase and tensin homolog	0.547
Wt1	Wilms tumor 1 homolog	0.432
Kdm2b	lysine (K)-specific demethylase 2B	0.419
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.394
Nos3	nitric oxide synthase 3, endothelial cell	0.299
Vegfa	vascular endothelial growth factor A	0.253
Nos2	nitric oxide synthase 2, inducible	0.169
H2-Ab1	histocompatibility 2, class II antigen A, beta 1	0.120
H2-Aa	histocompatibility 2, class II antigen A, alpha	0.119
Agtr1a	angiotensin II receptor, type 1a	0.115	Mouse
Nos1	nitric oxide synthase 1, neuronal	0.095
Rnf2	ring finger protein 2	0.095	Zebrafish
H2-Eb1	histocompatibility 2, class II antigen E beta	0.092
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.085
Cdx2	caudal type homeobox 2	0.078
Bcl2	B-cell leukemia/lymphoma 2	0.068
Vdr	vitamin D receptor	0.067
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.062
Cdkn2a	cyclin-dependent kinase inhibitor 2A	0.054
Bdkrb2	bradykinin receptor, beta 2	0.049
Ppp2ca	protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform	0.049
Pax2	paired box gene 2	0.048
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.048
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.046
Mmp9	matrix metallopeptidase 9	0.046
Trp73	transformation related protein 73	0.044
Prrx1	paired related homeobox 1	0.039
H2-DMa	histocompatibility 2, class II, locus DMa	0.038
Ar	androgen receptor	0.036
Ccl2	chemokine (C-C motif) ligand 2	0.034
Mdm2	transformed mouse 3T3 cell double minute 2	0.033
Col4a3	collagen, type IV, alpha 3	0.032
Trp53	transformation related protein 53	0.030
Tgfb1	transforming growth factor, beta 1	0.029
Shh	sonic hedgehog	0.029
Lyz2	lysozyme 2	0.029
Spdef	SAM pointed domain containing ets transcription factor	0.028
Cbx3	chromobox homolog 3 (Drosophila HP1 gamma)	0.028
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.027
Cd40	CD40 antigen	0.027
Trp63	transformation related protein 63	0.026	Mouse
Pik3cd	phosphatidylinositol 3-kinase catalytic delta polypeptide	0.026
Agtrap	angiotensin II, type I receptor-associated protein	0.026
Ppard	peroxisome proliferator activator receptor delta	0.025
Tnf	tumor necrosis factor	0.025
Gdnf	glial cell line derived neurotrophic factor	0.025
Hnrpdl	heterogeneous nuclear ribonucleoprotein D-like	0.024
Ube2d3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.024
Eif4a2	eukaryotic translation initiation factor 4A2	0.023
Nfkbia	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.023
Slc39a4	solute carrier family 39 (zinc transporter), member 4	0.022
Kiss1	KiSS-1 metastasis-suppressor	0.022
Pparg	peroxisome proliferator activated receptor gamma	0.022
Pcdh12	protocadherin 12	0.021
Bmi1	Bmi1 polycomb ring finger oncogene	0.020
Pou5f1	POU domain, class 5, transcription factor 1	0.020
Slc12a1	solute carrier family 12, member 1	0.020
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.020
Cav1	caveolin 1, caveolae protein	0.019
Tgfbr2	transforming growth factor, beta receptor II	0.019
Aqp2	aquaporin 2	0.019
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.018
Ttn	titin	0.017
Rb1	retinoblastoma 1	0.017
Ldlr	low density lipoprotein receptor	0.017
Ret	ret proto-oncogene	0.017
Vhl	von Hippel-Lindau tumor suppressor	0.017
Bcor	BCL6 interacting corepressor	0.016
Ctrb1	chymotrypsinogen B1	0.016
Nptx2	neuronal pentraxin 2	0.016
Pax3	paired box gene 3	0.016
Igh	immunoglobulin heavy chain complex	0.016
Wnt3a	wingless-related MMTV integration site 3A	0.016
Adcy4	adenylate cyclase 4	0.016
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.016
Mdm4	transformed mouse 3T3 cell double minute 4	0.015
Notch2	Notch gene homolog 2 (Drosophila)	0.015
Lhx1	LIM homeobox protein 1	0.015
Cbx7	chromobox homolog 7	0.015
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.015
Ptpru	protein tyrosine phosphatase, receptor type, U	0.014
Sct	secretin	0.014
Bcl6b	B-cell CLL/lymphoma 6, member B	0.013
Rybp	RING1 and YY1 binding protein	0.013
Efemp2	epidermal growth factor-containing fibulin-like extracellular matrix protein 2	0.013
Otx1	orthodenticle homolog 1 (Drosophila)	0.013
Popdc3	popeye domain containing 3	0.013
Pax9	paired box gene 9	0.013
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.013
Rsph1	radial spoke head 1 homolog (Chlamydomonas)	0.013
Lamc2	laminin, gamma 2	0.013
Sfn	stratifin	0.013
Ddx5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.013
Hsbp1	heat shock factor binding protein 1	0.013
Ppp1cb	protein phosphatase 1, catalytic subunit, beta isoform	0.013
Mas1	MAS1 oncogene	0.013
Meox1	mesenchyme homeobox 1	0.012
Mybl2	myeloblastosis oncogene-like 2	0.012
Emx2	empty spiracles homolog 2 (Drosophila)	0.012
Apc	adenomatosis polyposis coli	0.012
Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	0.012
Esr1	estrogen receptor 1 (alpha)	0.012
Fam134b	family with sequence similarity 134, member B	0.012
Agtr2	angiotensin II receptor, type 2	0.012	Mouse
Tiam1	T-cell lymphoma invasion and metastasis 1	0.012
Npy2r	neuropeptide Y receptor Y2	0.012
Fbn1	fibrillin 1	0.011
Vav2	vav 2 oncogene	0.011
Ager	advanced glycosylation end product-specific receptor	0.011
Itgb3	integrin beta 3	0.011
Csf1	colony stimulating factor 1 (macrophage)	0.011
Apln	apelin	0.011
Rxra	retinoid X receptor alpha	0.011
Zcchc10	zinc finger, CCHC domain containing 10	0.011
Olfr90	olfactory receptor 90	0.011
Slc10a6	solute carrier family 10 (sodium/bile acid cotransporter family), member 6	0.011
Arntl	aryl hydrocarbon receptor nuclear translocator-like	0.011
Pcgf2	polycomb group ring finger 2	0.011
Tlr2	toll-like receptor 2	0.010
Csnk2a1	casein kinase 2, alpha 1 polypeptide	0.010
Plat	plasminogen activator, tissue	0.010
Lef1	lymphoid enhancer binding factor 1	0.010
Vax1	ventral anterior homeobox containing gene 1	0.010	Zebrafish
Alx1	ALX homeobox 1	0.010
Rara	retinoic acid receptor, alpha	0.010