IMP

Process View

Mus musculus

7 genes annotated in mouse

lung vasculature development

The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "lung vasculature development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "lung vasculature development" (in gray)

Name	Description	Probability	Func Analog Organism
Nos3	nitric oxide synthase 3, endothelial cell	0.985
Id3	inhibitor of DNA binding 3	0.971	Mouse
Fgfr2	fibroblast growth factor receptor 2	0.969
Id1	inhibitor of DNA binding 1	0.954
Egfr	epidermal growth factor receptor	0.861
Tcf21	transcription factor 21	0.778
Bmp4	bone morphogenetic protein 4	0.759
Shh	sonic hedgehog	0.647
Twist2	twist homolog 2 (Drosophila)	0.479
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.471
Wt1	Wilms tumor 1 homolog	0.432
Notch2	Notch gene homolog 2 (Drosophila)	0.353
Tcf3	transcription factor 3	0.339
Kdr	kinase insert domain protein receptor	0.330
Itga3	integrin alpha 3	0.316
Pitx2	paired-like homeodomain transcription factor 2	0.276
Flt4	FMS-like tyrosine kinase 4	0.250
Fgf10	fibroblast growth factor 10	0.213
Rxra	retinoid X receptor alpha	0.212
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.196
Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)	0.172
Tgfb2	transforming growth factor, beta 2	0.161
Vegfa	vascular endothelial growth factor A	0.148
Rarb	retinoic acid receptor, beta	0.128
Lama5	laminin, alpha 5	0.123
Gata6	GATA binding protein 6	0.122
Smad6	MAD homolog 6 (Drosophila)	0.117
Ghr	growth hormone receptor	0.111
Gpc3	glypican 3	0.111
Tcf4	transcription factor 4	0.110
Lepr	leptin receptor	0.104
Nkx2-1	NK2 homeobox 1	0.103
Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.084
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.079
Pbx1	pre B-cell leukemia transcription factor 1	0.079
Foxa2	forkhead box A2	0.078
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.073
Col4a3	collagen, type IV, alpha 3	0.072
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.071
Sox18	SRY-box containing gene 18	0.067
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.067
Agtr1a	angiotensin II receptor, type 1a	0.067
Grb10	growth factor receptor bound protein 10	0.062
Tbx1	T-box 1	0.059
Ighmbp2	immunoglobulin mu binding protein 2	0.054
Hoxa5	homeobox A5	0.054
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.050
Tbx3	T-box 3	0.048
Esr1	estrogen receptor 1 (alpha)	0.048
Ift57	intraflagellar transport 57 homolog (Chlamydomonas)	0.047
Cd151	CD151 antigen	0.044
Nos1	nitric oxide synthase 1, neuronal	0.043
Kif3a	kinesin family member 3A	0.040
Pparg	peroxisome proliferator activated receptor gamma	0.040
Fzd4	frizzled homolog 4 (Drosophila)	0.040
Vhl	von Hippel-Lindau tumor suppressor	0.039
Meox2	mesenchyme homeobox 2	0.039
Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.039
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.038
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.037
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.036
Apoe	apolipoprotein E	0.034
Hes1	hairy and enhancer of split 1 (Drosophila)	0.033
Hic1	hypermethylated in cancer 1	0.033
Ednra	endothelin receptor type A	0.032
Nos2	nitric oxide synthase 2, inducible	0.032
Adam17	a disintegrin and metallopeptidase domain 17	0.030
Bmp5	bone morphogenetic protein 5	0.030
Ddr2	discoidin domain receptor family, member 2	0.030
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.029
Hoxa3	homeobox A3	0.027
Fgf8	fibroblast growth factor 8	0.026
Tgfbr2	transforming growth factor, beta receptor II	0.026
Pdgfc	platelet-derived growth factor, C polypeptide	0.026
Isl1	ISL1 transcription factor, LIM/homeodomain	0.026
Itga8	integrin alpha 8	0.024
Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.024
Nrp1	neuropilin 1	0.024
Rara	retinoic acid receptor, alpha	0.023
Meis2	Meis homeobox 2	0.023
Hoxa1	homeobox A1	0.023
Hand2	heart and neural crest derivatives expressed transcript 2	0.022
Ripply3	ripply3 homolog (zebrafish)	0.021
Tbx2	T-box 2	0.020
Msc	musculin	0.018	Mouse
Foxf1a	forkhead box F1a	0.018	Human
Pgr	progesterone receptor	0.018
Itga1	integrin alpha 1	0.017
Rarg	retinoic acid receptor, gamma	0.017
Sav1	salvador homolog 1 (Drosophila)	0.017
Apln	apelin	0.017
Hey1	hairy/enhancer-of-split related with YRPW motif 1	0.017
Rdh10	retinol dehydrogenase 10 (all-trans)	0.016
Id2	inhibitor of DNA binding 2	0.016	Mouse
Bdkrb2	bradykinin receptor, beta 2	0.016
Pthlh	parathyroid hormone-like peptide	0.016
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.016
Cav1	caveolin 1, caveolae protein	0.016
Hoxa2	homeobox A2	0.016
Mesp1	mesoderm posterior 1	0.016
Wwtr1	WW domain containing transcription regulator 1	0.016
Epas1	endothelial PAS domain protein 1	0.016
Igf1r	insulin-like growth factor I receptor	0.016
Bcl2	B-cell leukemia/lymphoma 2	0.015
Hoxb3	homeobox B3	0.015
Sema3f	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F	0.015
Flt1	FMS-like tyrosine kinase 1	0.015
Sox7	SRY-box containing gene 7	0.015
Ece1	endothelin converting enzyme 1	0.015
Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	0.015
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.014
Gdnf	glial cell line derived neurotrophic factor	0.014
Acvr1	activin A receptor, type 1	0.014
Emp2	epithelial membrane protein 2	0.013
Sox17	SRY-box containing gene 17	0.013
Olig2	oligodendrocyte transcription factor 2	0.013
Agtr2	angiotensin II receptor, type 2	0.013
Gja4	gap junction protein, alpha 4	0.013
Socs5	suppressor of cytokine signaling 5	0.012
Ar	androgen receptor	0.012
Pten	phosphatase and tensin homolog	0.012
Yap1	yes-associated protein 1	0.012
Snai2	snail homolog 2 (Drosophila)	0.012
Hbegf	heparin-binding EGF-like growth factor	0.011
Npr3	natriuretic peptide receptor 3	0.011
Slc9a3r2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.011
Bmp6	bone morphogenetic protein 6	0.011
Ptgs2	prostaglandin-endoperoxide synthase 2	0.011
She	src homology 2 domain-containing transforming protein E	0.011
Fuz	fuzzy homolog (Drosophila)	0.010
Nt5e	5' nucleotidase, ecto	0.010
Gata2	GATA binding protein 2	0.010
Tal1	T-cell acute lymphocytic leukemia 1	0.010
Tspan12	tetraspanin 12	0.010