IMP

Process View

Mus musculus

8 genes annotated in mouse

tongue morphogenesis

The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "tongue morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "tongue morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Pitx2	paired-like homeodomain transcription factor 2	0.998
Fgfr2	fibroblast growth factor receptor 2	0.996
Tbx3	T-box 3	0.994	Mouse
Otx2	orthodenticle homolog 2 (Drosophila)	0.989
Pax2	paired box gene 2	0.964
Gli3	GLI-Kruppel family member GLI3	0.953
Fgf8	fibroblast growth factor 8	0.929	Zebrafish
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.899
Foxc1	forkhead box C1	0.888
Pax3	paired box gene 3	0.851
Pitx1	paired-like homeodomain transcription factor 1	0.838
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.834
Hoxa1	homeobox A1	0.819
Vangl2	vang-like 2 (van gogh, Drosophila)	0.760
Eya1	eyes absent 1 homolog (Drosophila)	0.738
Sox2	SRY-box containing gene 2	0.673
Tcfap2a	transcription factor AP-2, alpha	0.624
Rarg	retinoic acid receptor, gamma	0.599
Tbx1	T-box 1	0.592
Foxc2	forkhead box C2	0.519
Chd7	chromodomain helicase DNA binding protein 7	0.504
Fgf10	fibroblast growth factor 10	0.483
Foxg1	forkhead box G1	0.375
Gsc	goosecoid homeobox	0.363
Hand2	heart and neural crest derivatives expressed transcript 2	0.356
Otx1	orthodenticle homolog 1 (Drosophila)	0.277
Hoxd13	homeobox D13	0.252	Mouse
Hoxa13	homeobox A13	0.237	Mouse
Isl1	ISL1 transcription factor, LIM/homeodomain	0.234
Hoxd11	homeobox D11	0.187
Trp63	transformation related protein 63	0.187
Emx1	empty spiracles homolog 1 (Drosophila)	0.182
Gja5	gap junction protein, alpha 5	0.168
Hand1	heart and neural crest derivatives expressed transcript 1	0.166
Nog	noggin	0.165
Hoxa2	homeobox A2	0.159
Bmp4	bone morphogenetic protein 4	0.159	Rat
Sall4	sal-like 4 (Drosophila)	0.154
Lhx1	LIM homeobox protein 1	0.147
Hes1	hairy and enhancer of split 1 (Drosophila)	0.146
Emx2	empty spiracles homolog 2 (Drosophila)	0.145
Lmx1a	LIM homeobox transcription factor 1 alpha	0.143
Gbx2	gastrulation brain homeobox 2	0.130
Hcn4	hyperpolarization-activated, cyclic nucleotide-gated K+ 4	0.124
Gata6	GATA binding protein 6	0.121
Jag1	jagged 1	0.118
Neurog2	neurogenin 2	0.114
Pax6	paired box gene 6	0.112
Fgf3	fibroblast growth factor 3	0.109
T	brachyury	0.109	Mouse
Smad6	MAD homolog 6 (Drosophila)	0.107
Sox9	SRY-box containing gene 9	0.100
Tbx4	T-box 4	0.094	Mouse
Bdnf	brain derived neurotrophic factor	0.094
Pou4f2	POU domain, class 4, transcription factor 2	0.093
Wnt5a	wingless-related MMTV integration site 5A	0.089
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.082	Mouse
Tcf21	transcription factor 21	0.081
Rarb	retinoic acid receptor, beta	0.077
Tcfap2c	transcription factor AP-2, gamma	0.077
Gata3	GATA binding protein 3	0.074
Tbx5	T-box 5	0.071	Mouse
Sox11	SRY-box containing gene 11	0.070
Wt1	Wilms tumor 1 homolog	0.070
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.069	Mouse
Hoxa10	homeobox A10	0.068
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.068
Scn5a	sodium channel, voltage-gated, type V, alpha	0.066
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.065
Fgfr1	fibroblast growth factor receptor 1	0.061
Wnt3a	wingless-related MMTV integration site 3A	0.059
Lrp6	low density lipoprotein receptor-related protein 6	0.059
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.057
Myf5	myogenic factor 5	0.055
Msx2	homeobox, msh-like 2	0.054
Gdnf	glial cell line derived neurotrophic factor	0.054
Lef1	lymphoid enhancer binding factor 1	0.053
Rag2	recombination activating gene 2	0.051
Gata4	GATA binding protein 4	0.051
Hmx3	H6 homeobox 3	0.050
Foxf1a	forkhead box F1a	0.050
Prrx1	paired related homeobox 1	0.050
Neurod4	neurogenic differentiation 4	0.049
Ighmbp2	immunoglobulin mu binding protein 2	0.049
Rxra	retinoid X receptor alpha	0.045
Hoxd3	homeobox D3	0.045
Efnb2	ephrin B2	0.045
Dlx5	distal-less homeobox 5	0.044
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.043
Pou5f1	POU domain, class 5, transcription factor 1	0.043
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.042
Hoxb4	homeobox B4	0.041
Smo	smoothened homolog (Drosophila)	0.041
Alx3	aristaless-like homeobox 3	0.041
Nodal	nodal	0.037
Hoxa11	homeobox A11	0.036
Hoxb1	homeobox B1	0.035
Cxadr	coxsackie virus and adenovirus receptor	0.035
Hoxa3	homeobox A3	0.034
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.033
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.033
Hoxb3	homeobox B3	0.033
Pbx1	pre B-cell leukemia transcription factor 1	0.032
Lrp5	low density lipoprotein receptor-related protein 5	0.032
Tbx2	T-box 2	0.032	Mouse
Hoxb2	homeobox B2	0.029
Pten	phosphatase and tensin homolog	0.029
Dll4	delta-like 4 (Drosophila)	0.029
En1	engrailed 1	0.029
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.028	Mouse
Msx1	homeobox, msh-like 1	0.028
Tlx3	T-cell leukemia, homeobox 3	0.028
Lhx9	LIM homeobox protein 9	0.027
Hoxa4	homeobox A4	0.027
Vegfa	vascular endothelial growth factor A	0.026
Nanog	Nanog homeobox	0.025
Twist2	twist homolog 2 (Drosophila)	0.025
Bnc1	basonuclin 1	0.024
Xirp1	xin actin-binding repeat containing 1	0.024
Fzd8	frizzled homolog 8 (Drosophila)	0.024
Irx3	Iroquois related homeobox 3 (Drosophila)	0.024
Ctnnb1	catenin (cadherin associated protein), beta 1	0.024
Ptk7	PTK7 protein tyrosine kinase 7	0.023
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.023
Bmpr1a	bone morphogenetic protein receptor, type 1A	0.022
Neurog1	neurogenin 1	0.021
Fgfr3	fibroblast growth factor receptor 3	0.021
Lrp2	low density lipoprotein receptor-related protein 2	0.020
Gata5	GATA binding protein 5	0.020
Bmp7	bone morphogenetic protein 7	0.020
Foxe3	forkhead box E3	0.020
Ret	ret proto-oncogene	0.020
Pitx3	paired-like homeodomain transcription factor 3	0.020
Fgf17	fibroblast growth factor 17	0.020
Uncx	UNC homeobox	0.019
Tead3	TEA domain family member 3	0.019
Rnf2	ring finger protein 2	0.019
Fbn2	fibrillin 2	0.018
Hmx1	H6 homeobox 1	0.018
Pax7	paired box gene 7	0.018
Zeb1	zinc finger E-box binding homeobox 1	0.018
Pax1	paired box gene 1	0.018
Sin3a	transcriptional regulator, SIN3A (yeast)	0.018
Hoxd1	homeobox D1	0.018
Col13a1	collagen, type XIII, alpha 1	0.018
Foxa2	forkhead box A2	0.017
Gli2	GLI-Kruppel family member GLI2	0.017
Hdac2	histone deacetylase 2	0.017
Apc	adenomatosis polyposis coli	0.017
Snai1	snail homolog 1 (Drosophila)	0.017
Tbx15	T-box 15	0.017	Mouse
Cdx2	caudal type homeobox 2	0.016
Myl7	myosin, light polypeptide 7, regulatory	0.016
Pax9	paired box gene 9	0.016
Wnt11	wingless-related MMTV integration site 11	0.016
Pax8	paired box gene 8	0.016
Mnx1	motor neuron and pancreas homeobox 1	0.015
Sim2	single-minded homolog 2 (Drosophila)	0.015
Wnt1	wingless-related MMTV integration site 1	0.015
Foxb1	forkhead box B1	0.015
Efna4	ephrin A4	0.015
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.015
Meox2	mesenchyme homeobox 2	0.015
Tead2	TEA domain family member 2	0.014
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.014
Col2a1	collagen, type II, alpha 1	0.014
Foxi1	forkhead box I1	0.014
Wnt10b	wingless related MMTV integration site 10b	0.014
Pkp1	plakophilin 1	0.014
Noto	notochord homolog (Xenopus laevis)	0.014
Fgf15	fibroblast growth factor 15	0.014
Prrx2	paired related homeobox 2	0.013
Runx2	runt related transcription factor 2	0.013
Gli1	GLI-Kruppel family member GLI1	0.013
Krt14	keratin 14	0.013
Hoxa5	homeobox A5	0.013
Hoxa9	homeobox A9	0.013
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.013
Hey2	hairy/enhancer-of-split related with YRPW motif 2	0.013
Hoxd4	homeobox D4	0.013
Lmx1b	LIM homeobox transcription factor 1 beta	0.013
Hoxd9	homeobox D9	0.013
Hoxb13	homeobox B13	0.013	Mouse
Plag1	pleiomorphic adenoma gene 1	0.012
Hmga2	high mobility group AT-hook 2	0.012
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.012
Col17a1	collagen, type XVII, alpha 1	0.012
Alx1	ALX homeobox 1	0.012
Eya4	eyes absent 4 homolog (Drosophila)	0.012
Myog	myogenin	0.012
Krt15	keratin 15	0.012
Sox3	SRY-box containing gene 3	0.012
Wnt3	wingless-related MMTV integration site 3	0.011
Dlx1	distal-less homeobox 1	0.011
Ephb4	Eph receptor B4	0.011
Foxa1	forkhead box A1	0.011
Tal1	T-cell acute lymphocytic leukemia 1	0.011
Rara	retinoic acid receptor, alpha	0.011
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.011
Efna2	ephrin A2	0.011
Shox2	short stature homeobox 2	0.011
Skor1	SKI family transcriptional corepressor 1	0.011
Sox4	SRY-box containing gene 4	0.011
Nynrin	NYN domain and retroviral integrase containing	0.011
Alx4	aristaless-like homeobox 4	0.011
Cdon	cell adhesion molecule-related/down-regulated by oncogenes	0.011
Ntf3	neurotrophin 3	0.011
Myl3	myosin, light polypeptide 3	0.011
Pou3f3	POU domain, class 3, transcription factor 3	0.011
Mesp1	mesoderm posterior 1	0.011
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.010
Fgf18	fibroblast growth factor 18	0.010
Sox7	SRY-box containing gene 7	0.010