IMP

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Mus musculus

15 genes annotated in mouse

Multi-species View

microtubule depolymerization

GO:0007019

The removal of tubulin heterodimers from one or both ends of a microtubule.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "microtubule depolymerization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "microtubule depolymerization" (in gray)

Name	Description	Probability	Func Analog Organism
Cdk1	cyclin-dependent kinase 1	0.990
Prc1	protein regulator of cytokinesis 1	0.982	Worm Fly
Ccnb1	cyclin B1	0.980	Human
Cdc20	cell division cycle 20 homolog (S. cerevisiae)	0.975
Ccna2	cyclin A2	0.966
Ccnb2	cyclin B2	0.896
Kif20a	kinesin family member 20A	0.888
Kif11	kinesin family member 11	0.827	Fly
Plk1	polo-like kinase 1 (Drosophila)	0.766
Birc5	baculoviral IAP repeat-containing 5	0.749
Anln	anillin, actin binding protein	0.723
Hmmr	hyaluronan mediated motility receptor (RHAMM)	0.721
Racgap1	Rac GTPase-activating protein 1	0.721
Macf1	microtubule-actin crosslinking factor 1	0.670	Fly
Dcx	doublecortin	0.547	Worm
Cdca8	cell division cycle associated 8	0.465
Kif22	kinesin family member 22	0.431
Aurkb	aurora kinase B	0.394	Human
Ckap2	cytoskeleton associated protein 2	0.394
Braf	Braf transforming gene	0.372
Top2a	topoisomerase (DNA) II alpha	0.317
Dclk1	doublecortin-like kinase 1	0.312	Worm
Trp53	transformation related protein 53	0.306
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.283
Trim63	tripartite motif-containing 63	0.257	Mouse
Aurka	aurora kinase A	0.257	Human
H2afx	H2A histone family, member X	0.249
Dlgap5	discs, large (Drosophila) homolog-associated protein 5	0.237
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.234
Cks2	CDC28 protein kinase regulatory subunit 2	0.215
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.210
Ube2c	ubiquitin-conjugating enzyme E2C	0.200
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.189
Cenpa	centromere protein A	0.184
Trim55	tripartite motif-containing 55	0.181	Mouse
Odf2	outer dense fiber of sperm tails 2	0.168
Cdkn3	cyclin-dependent kinase inhibitor 3	0.165
Kif4	kinesin family member 4	0.161
Egfr	epidermal growth factor receptor	0.160
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.153
Cdc25c	cell division cycle 25 homolog C (S. pombe)	0.151
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.149
Ncaph	non-SMC condensin I complex, subunit H	0.146
Kif2c	kinesin family member 2C	0.138	Human Worm
Gtse1	G two S phase expressed protein 1	0.137
Bdnf	brain derived neurotrophic factor	0.135
Clasp1	CLIP associating protein 1	0.135
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.134
Tcf19	transcription factor 19	0.118
Asf1b	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.113
Nuf2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.109
Tbx10	T-box 10	0.107
Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	0.105
Fam64a	family with sequence similarity 64, member A	0.104
Lmna	lamin A	0.104
Pax2	paired box gene 2	0.094
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.092
Mki67	antigen identified by monoclonal antibody Ki 67	0.089
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.080
Aspm	asp (abnormal spindle)-like, microcephaly associated (Drosophila)	0.073
Bub1b	budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)	0.069
Spag5	sperm associated antigen 5	0.067
Cdca5	cell division cycle associated 5	0.066
Capn1	calpain 1	0.065
Kif23	kinesin family member 23	0.061
Lmnb1	lamin B1	0.059
D2Ertd750e	DNA segment, Chr 2, ERATO Doi 750, expressed	0.058
Mxd3	Max dimerization protein 3	0.058
Smad3	MAD homolog 3 (Drosophila)	0.055
Tacc3	transforming, acidic coiled-coil containing protein 3	0.054
Plaa	phospholipase A2, activating protein	0.049
Epas1	endothelial PAS domain protein 1	0.049
Gsk3b	glycogen synthase kinase 3 beta	0.047
Foxj1	forkhead box J1	0.047
Gria4	glutamate receptor, ionotropic, AMPA4 (alpha 4)	0.046
Exoc3	exocyst complex component 3	0.046
Pou3f4	POU domain, class 3, transcription factor 4	0.045
Mad2l1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.045
Trp63	transformation related protein 63	0.044
Shc3	src homology 2 domain-containing transforming protein C3	0.043
Nf1	neurofibromatosis 1	0.043
Gata3	GATA binding protein 3	0.043
Hmgb2	high mobility group box 2	0.043
Rxra	retinoid X receptor alpha	0.042
Mapk8	mitogen-activated protein kinase 8	0.040
Pten	phosphatase and tensin homolog	0.040
Clip1	CAP-GLY domain containing linker protein 1	0.040
Incenp	inner centromere protein	0.039
Fam83d	family with sequence similarity 83, member D	0.038
Mstn	myostatin	0.036
Ttk	Ttk protein kinase	0.035
Fzr1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.035
Smc2	structural maintenance of chromosomes 2	0.033
Mis18bp1	MIS18 binding protein 1	0.033
Pbk	PDZ binding kinase	0.032
2810417H13Rik	RIKEN cDNA 2810417H13 gene	0.032
Tuba1a	tubulin, alpha 1A	0.031
Fgfbp1	fibroblast growth factor binding protein 1	0.030
Rrm2	ribonucleotide reductase M2	0.029
Clasp2	CLIP associating protein 2	0.029
Nefm	neurofilament, medium polypeptide	0.029
Ect2	ect2 oncogene	0.028
Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1	0.027
Tcf21	transcription factor 21	0.027
Ccnf	cyclin F	0.027
Nusap1	nucleolar and spindle associated protein 1	0.027
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.026
Kif3a	kinesin family member 3A	0.025
Gabrb3	gamma-aminobutyric acid (GABA) A receptor, subunit beta 3	0.025
Cenpn	centromere protein N	0.025
Smc4	structural maintenance of chromosomes 4	0.025
Nkx2-1	NK2 homeobox 1	0.024
Ptgs2	prostaglandin-endoperoxide synthase 2	0.024
C330027C09Rik	RIKEN cDNA C330027C09 gene	0.022
Zic3	zinc finger protein of the cerebellum 3	0.022
Kntc1	kinetochore associated 1	0.022
Spna2	spectrin alpha 2	0.022
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.022
Depdc1b	DEP domain containing 1B	0.022
Nkx2-4	NK2 transcription factor related, locus 4 (Drosophila)	0.021
Lancl2	LanC (bacterial lantibiotic synthetase component C)-like 2	0.021
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.020
Ccdc99	coiled-coil domain containing 99	0.019
Trim59	tripartite motif-containing 59	0.019	Mouse
Slc4a2	solute carrier family 4 (anion exchanger), member 2	0.019
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Plk4	polo-like kinase 4 (Drosophila)	0.019
Bub1	budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)	0.019
Depdc1a	DEP domain containing 1a	0.018
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.018
Gria1	glutamate receptor, ionotropic, AMPA1 (alpha 1)	0.018
Gabra1	gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1	0.018
Sgcd	sarcoglycan, delta (dystrophin-associated glycoprotein)	0.018
Efnb2	ephrin B2	0.018
Pou4f3	POU domain, class 4, transcription factor 3	0.018
Nap1l2	nucleosome assembly protein 1-like 2	0.018
Tsc2	tuberous sclerosis 2	0.017
Cdc25b	cell division cycle 25 homolog B (S. pombe)	0.017
Ids	iduronate 2-sulfatase	0.017
Mastl	microtubule associated serine/threonine kinase-like	0.017
Cdca2	cell division cycle associated 2	0.017
Ctnnb1	catenin (cadherin associated protein), beta 1	0.017
Smn1	survival motor neuron 1	0.017
Wbp4	WW domain binding protein 4	0.016
Kif3b	kinesin family member 3B	0.016
Cdc27	cell division cycle 27 homolog (S. cerevisiae)	0.015
Asap1	ArfGAP with SH# domain, ankyrin repeat and PH domain1	0.015
Plcb1	phospholipase C, beta 1	0.015
Exoc7	exocyst complex component 7	0.015
Zfpm2	zinc finger protein, multitype 2	0.015
Kcnj3	potassium inwardly-rectifying channel, subfamily J, member 3	0.015
Sae1	SUMO1 activating enzyme subunit 1	0.014
E2f8	E2F transcription factor 8	0.014
Ska1	spindle and kinetochore associated complex subunit 1	0.014
Mtap7d1	microtubule-associated protein 7 domain containing 1	0.014
Fgf14	fibroblast growth factor 14	0.014	Mouse
Stk11	serine/threonine kinase 11	0.014
Usp8	ubiquitin specific peptidase 8	0.014
2010317E24Rik	RIKEN cDNA 2010317E24 gene	0.014
Prkci	protein kinase C, iota	0.014
Chrna4	cholinergic receptor, nicotinic, alpha polypeptide 4	0.014
Gpr83	G protein-coupled receptor 83	0.014
Anapc2	anaphase promoting complex subunit 2	0.014
Prr11	proline rich 11	0.013
Hcrt	hypocretin	0.013
Dync1h1	dynein cytoplasmic 1 heavy chain 1	0.013
Gria3	glutamate receptor, ionotropic, AMPA3 (alpha 3)	0.013
Btbd3	BTB (POZ) domain containing 3	0.013
Brca1	breast cancer 1	0.013
4930427A07Rik	RIKEN cDNA 4930427A07 gene	0.013
Kcnq2	potassium voltage-gated channel, subfamily Q, member 2	0.013
Ndc80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.013
Lepr	leptin receptor	0.013
Dtna	dystrobrevin alpha	0.013
Sox9	SRY-box containing gene 9	0.013
Fgfr2	fibroblast growth factor receptor 2	0.013
Esr2	estrogen receptor 2 (beta)	0.013
Gpr37	G protein-coupled receptor 37	0.013
Cenpe	centromere protein E	0.013
Foxm1	forkhead box M1	0.012
Ylpm1	YLP motif containing 1	0.012
Espl1	extra spindle poles-like 1 (S. cerevisiae)	0.012
Shh	sonic hedgehog	0.012
Emx1	empty spiracles homolog 1 (Drosophila)	0.012
Bcl2	B-cell leukemia/lymphoma 2	0.012
Usp22	ubiquitin specific peptidase 22	0.012
P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	0.012
Nf2	neurofibromatosis 2	0.012
Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	0.012
Rad21	RAD21 homolog (S. pombe)	0.012
Cep55	centrosomal protein 55	0.012
Fgf5	fibroblast growth factor 5	0.012	Mouse
Iqcb1	IQ calmodulin-binding motif containing 1	0.011
Oprl1	opioid receptor-like 1	0.011
Pax3	paired box gene 3	0.011
Wrn	Werner syndrome homolog (human)	0.011
Gja1	gap junction protein, alpha 1	0.011
Irx6	Iroquois related homeobox 6 (Drosophila)	0.011
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.011
Cenpf	centromere protein F	0.011
Cenpm	centromere protein M	0.011
Musk	muscle, skeletal, receptor tyrosine kinase	0.011
Reln	reelin	0.011
Ppp1r9b	protein phosphatase 1, regulatory subunit 9B	0.011
Rgs4	regulator of G-protein signaling 4	0.011
Myo18a	myosin XVIIIA	0.011
Zfp40	zinc finger protein 40	0.011
Pfkfb2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2	0.011
Nefl	neurofilament, light polypeptide	0.011
Kpna2	karyopherin (importin) alpha 2	0.011
Atcay	ataxia, cerebellar, Cayman type homolog (human)	0.010
Cks1b	CDC28 protein kinase 1b	0.010
Fzd3	frizzled homolog 3 (Drosophila)	0.010
Trim54	tripartite motif-containing 54	0.010
BC030867	cDNA sequence BC030867	0.010
Socs5	suppressor of cytokine signaling 5	0.010
Adra1a	adrenergic receptor, alpha 1a	0.010
AA516738	expressed sequence AA516738	0.010
E130306D19Rik	RIKEN cDNA E130306D19 gene	0.010