IMP

Process View

Danio rerio

16 genes annotated in zebrafish

Multi-species View

cellular metal ion homeostasis

GO:0006875

Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular metal ion homeostasis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular metal ion homeostasis" (in gray)

Name	Description	Probability	Func Analog Organism
spry4	sprouty (Drosophila) homolog 4	0.261
atp1b1b	ATPase, Na+/K+ transporting, beta 1b polypeptide	0.189
dusp6	dual specificity phosphatase 6	0.143
hspb7	heat shock protein family, alpha-crystallin-related, b7	0.132
wnt10a	wingless-type MMTV integration site family, member 10a	0.120	Zebrafish
chat	choline acetyltransferase	0.095
cacnb4a	calcium channel, voltage-dependent, beta 4a subunit	0.075	Mouse
tnnt2a	troponin T2a, cardiac	0.067	Fly
wnt10b	wingless-type MMTV integration site family, member 10b	0.060	Zebrafish
trpv6	transient receptor potential cation channel, subfamily V, member 6	0.060	Rat
mc4r	melanocortin 4 receptor	0.059
opn4l	opsin 4, like	0.053
stac3	SH3 and cysteine rich domain 3	0.052
tfr1a	transferrin receptor 1a	0.050
valopa	vertebrate ancient long opsin a	0.047	Zebrafish
opn1lw1	opsin 1 (cone pigments), long-wave-sensitive, 1	0.046	Zebrafish
wnt11r	wingless-type MMTV integration site family, member 11, related	0.045	Zebrafish
si:ch73-60e21.1	si:ch73-60e21.1	0.044
cx39.9	connexin 39.9	0.042
tnni2a.4	troponin I, skeletal, fast 2a.4	0.042
ppargc1al	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha like	0.041
chrm2a	cholinergic receptor, muscarinic 2a	0.041
dbh	dopamine beta hydroxylase	0.039
opn1sw2	opsin 1 (cone pigments), short-wave-sensitive 2	0.039	Zebrafish
cmlc1	cardiac myosin light chain-1	0.037
atp1b2b	ATPase, Na+/K+ transporting, beta 2b polypeptide	0.037
opn4a	opsin 4a (melanopsin)	0.035	Zebrafish
tnnt3a	troponin T3a, skeletal, fast	0.035	Fly
wnt1	wingless-type MMTV integration site family, member 1	0.034	Zebrafish
hbaa1	hemoglobin alpha adult-1	0.033
bmp7a	bone morphogenetic protein 7a	0.032
epb41	erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)	0.031
tpma	alpha-tropomyosin	0.031
pvalb2	parvalbumin 2	0.031
appa	amyloid beta (A4) precursor protein a	0.030	Mouse
epas1b	endothelial PAS domain protein 1b	0.030
lama2	laminin, alpha 2	0.030
snai1a	snail homolog 1a (Drosophila)	0.030
atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	0.029	Human Zebrafish
ttna	titin a	0.029
esrra	estrogen-related receptor alpha	0.029
fbp1b	fructose-1,6-bisphosphatase 1b	0.029
myhz2	myosin, heavy polypeptide 2, fast muscle specific	0.029
mmp9	matrix metalloproteinase 9	0.029
actn3a	actinin alpha 3a	0.028
tnnc1a	troponin C type 1a (slow)	0.028
col11a2	collagen type XI alpha-2	0.028
ckma	creatine kinase, muscle a	0.028
atp6v1al	ATPase, H+ transporting, lysosomal V1 subunit A, like	0.027
alcamb	activated leukocyte cell adhesion molecule b	0.027
bcl2	B-cell leukemia/lymphoma 2	0.027	Mouse
csf3r	colony stimulating factor 3 receptor (granulocyte)	0.026
opn1mw1	opsin 1 (cone pigments), medium-wave-sensitive, 1	0.026	Zebrafish
ldb3b	LIM domain binding 3b	0.026
si:dkey-273o13.1	si:dkey-273o13.1	0.025
ptger4a	prostaglandin E receptor 4 (subtype EP4) a	0.025
myd88	myeloid differentiation primary response gene (88)	0.025
mc1r	melanocortin 1 receptor	0.025
hspb12	heat shock protein, alpha-crystallin-related, b12	0.024
rbm24a	RNA binding motif protein 24a	0.022
opn1sw1	opsin 1 (cone pigments), short-wave-sensitive 1	0.022	Zebrafish
hbbe1.1	hemoglobin beta embryonic-1.1	0.022
aco1	aconitase 1, soluble	0.022	Mouse
gja3	gap junction protein, alpha 3	0.022
valopb	vertebrate ancient long opsin b	0.021	Zebrafish
glra1	glycine receptor, alpha 1	0.021
gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.021
slc11a2	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2	0.021
bmp4	bone morphogenetic protein 4	0.020	Rat
itgb1a	integrin, beta 1a	0.020
tnnt3b	troponin T3b, skeletal, fast	0.020	Fly
mchr1a	melanin-concentrating hormone receptor 1a	0.020
tfa	transferrin-a	0.019
lin7a	lin-7 homolog A (C. elegans)	0.019
gngt2b	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2b	0.019
atp1a3a	ATPase, Na+/K+ transporting, alpha 3a polypeptide	0.019	Zebrafish
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.019
smyhc1l	slow myosin heavy chain 1, like	0.019
grin1a	glutamate receptor, ionotropic, N-methyl D-aspartate 1a	0.018
pvalb4	parvalbumin 4	0.018
trpc1	transient receptor potential cation channel, subfamily C, member 1	0.018	Human Fly
nbl1	neuroblastoma, suppression of tumorigenicity 1	0.017
gad2	glutamate decarboxylase 2	0.017
wnt7aa	wingless-type MMTV integration site family, member 7Aa	0.017	Zebrafish
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.017
zgc:193613	zgc:193613	0.017
LOC566708	FL cytokine receptor-like	0.017
mef2ca	myocyte enhancer factor 2ca	0.017
atp1b1a	ATPase, Na+/K+ transporting, beta 1a polypeptide	0.017	Human Mouse
cx36.7	connexin 36.7	0.017
tbx5a	T-box 5a	0.017
pi4kb	phosphatidylinositol 4-kinase, catalytic, beta	0.017
ireb2	iron-responsive element binding protein 2	0.017	Mouse
il6r	interleukin 6 receptor	0.017
wls	wntless homolog (Drosophila)	0.016
hcst	hematopoietic cell signal transducer	0.016
inhbaa	inhibin, beta Aa	0.016
nr2f6a	nuclear receptor subfamily 2, group F, member 6a	0.016
crabp2b	cellular retinoic acid binding protein 2, b	0.016
or107-1	odorant receptor, family D, subfamily 107, member 1	0.016
veph	ventricular zone expressed PH domain protein	0.016
oxtl	oxytocin-like	0.016	Rat
ppdpfa	pancreatic progenitor cell differentiation and proliferation factor a	0.016
scn1ba	sodium channel, voltage-gated, type I, beta a	0.015
rag1	recombination activating gene 1	0.015
zgc:64040	zgc:64040	0.015
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.015
arf1	ADP-ribosylation factor 1	0.015	Human
tnni1b	troponin I, skeletal, slow b	0.015
lpar1	lysophosphatidic acid receptor 1	0.015	Rat
tnnc1b	troponin C type 1b (slow)	0.015
ppp4cb	protein phosphatase 4 (formerly X), catalytic subunit b	0.014
urod	uroporphyrinogen decarboxylase	0.014
slc4a1a	solute carrier family 4, anion exchanger, member 1a	0.014
gata1a	GATA binding protein 1a	0.014
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.014
oprd1a	opioid receptor, delta 1a	0.014
dag1	dystroglycan 1	0.014
mc2r	melanocortin 2 receptor	0.014
jak1	Janus kinase 1	0.014
has3	hyaluronan synthase 3	0.014
scn1lab	sodium channel, voltage-gated, type I like, alpha b	0.014
myhc4	myosin heavy chain 4	0.014
pthlh	parathyroid hormone-like hormone	0.014
ahcyl2	S-adenosylhomocysteine hydrolase-like 2	0.014
f2rl1.2	coagulation factor II (thrombin) receptor-like 1.2	0.014
opn4x1	opsin 4x1	0.013	Zebrafish
tbx1	T-box 1	0.013
zgc:63947	zgc:63947	0.013
slc25a37	solute carrier family 25, member 37	0.013
mtdha	metadherin a	0.013
LOC557062	hypothetical protein LOC557062	0.013
gngt1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.013
sec24d	SEC24 family, member D (S. cerevisiae)	0.013
rnd3a	Rho family GTPase 3a	0.013
slc25a3a	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3a	0.013	Yeast
matn1	matrilin 1	0.013
sars	seryl-tRNA synthetase	0.013
sncgb	synuclein, gamma b (breast cancer-specific protein 1)	0.013
men1	multiple endocrine neoplasia type 1 and multiple endocrine neoplasia I	0.012
scn12ab	sodium channel, voltage gated, type XII, alpha b	0.012
dlx4a	distal-less homeobox gene 4a	0.012
im:6903943	im:6903943	0.012
pcsk5a	proprotein convertase subtilisin/kexin type 5a	0.012
tp73	tumor protein p73	0.012
slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.012
ptpra	protein tyrosine phosphatase, receptor type, A	0.012
ca8	carbonic anhydrase VIII	0.012
zgc:92903	zgc:92903	0.012
cacnb4b	calcium channel, voltage-dependent, beta 4b subunit	0.012	Mouse
acvr2b	activin receptor IIb	0.012
or115-10	odorant receptor, family F, subfamily 115, member 10	0.012
musk	muscle, skeletal, receptor tyrosine kinase	0.012
crybb1	crystallin, beta B1	0.012
atp2a1l	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 like	0.012	Zebrafish Worm Fly
atp2b4	ATPase, Ca++ transporting, plasma membrane 4	0.012
atp1a1a.4	ATPase, Na+/K+ transporting, alpha 1a.4 polypeptide	0.012	Human Zebrafish
clptm1	cleft lip and palate associated transmembrane protein 1	0.012
myh6	myosin, heavy polypeptide 6, cardiac muscle, alpha	0.012
gna13a	guanine nucleotide binding protein (G protein), alpha 13a	0.012
guca1b	guanylate cyclase activator 1B	0.012
nr5a1b	nuclear receptor subfamily 5, group A, member 1b	0.012
fbln1	fibulin 1	0.011
ca2	carbonic anhydrase II	0.011
tgm2b	transglutaminase 2b	0.011
cps1	carbamoyl-phosphate synthase 1, mitochondrial	0.011
myhz1.1	myosin, heavy polypeptide 1.1, skeletal muscle	0.011
unc45b	unc-45 homolog B (C. elegans)	0.011
tfpi2	tissue factor pathway inhibitor 2	0.011
drd2b	dopamine receptor D2b	0.011	Human Rat
slc6a6	solute carrier family 6 (neurotransmitter transporter, taurine), member 6	0.011
htr1aa	5-hydroxytryptamine (serotonin) receptor 1A a	0.011
LOC100006361	galanin-like	0.011
c1ql4l	complement component 1, q subcomponent-like 4 like	0.011
zfyve26	zinc finger, FYVE domain containing 26	0.011
myl1	myosin, light chain 1, alkali; skeletal, fast	0.011
hspg2	heparan sulfate proteoglycan 2	0.011
ache	acetylcholinesterase	0.011
cdh23	cadherin-like 23	0.011	Human
eaf2	ELL associated factor 2	0.011
fmnl2b	formin-like 2b	0.011
nt5c2l1	5'-nucleotidase, cytosolic II, like 1	0.011
acvr2a	activin receptor IIa	0.011
zbtb4	zinc finger and BTB domain containing 4	0.011
cpox	coproporphyrinogen oxidase	0.010
psen1	presenilin 1	0.010	Human Mouse
zgc:77752	zgc:77752	0.010
zgc:153063	zgc:153063	0.010
atp1a1a.2	ATPase, Na+/K+ transporting, alpha 1a.2 polypeptide	0.010	Human Zebrafish
scinla	scinderin like a	0.010
btg1	B-cell translocation gene 1	0.010
nkd1	naked cuticle homolog 1 (Drosophila)	0.010
mylz2	myosin, light polypeptide 2, skeletal muscle	0.010
hmgb3a	high-mobility group box 3a	0.010
lass2	LAG1 homolog, ceramide synthase 2 (S. cerevisiae)	0.010
elovl1b	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1b	0.010
atp2a2a	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a	0.010	Human Zebrafish Mouse Worm Fly
wu:fc18d04	wu:fc18d04	0.010
pitx3	paired-like homeodomain transcription factor 3	0.010
pdlim3b	PDZ and LIM domain 3b	0.010