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Danio rerio

17 genes annotated in zebrafish

notochord morphogenesis

The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "notochord morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "notochord morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
flh	floating head	1.000
chd	chordin	0.983	Zebrafish
lamb1a	laminin, beta 1a	0.979
ndr2	nodal-related 2	0.970
shha	sonic hedgehog a	0.951
lamc1	laminin, gamma 1	0.947
col8a1a	collagen, type VIII, alpha 1a	0.946
dharma	dharma	0.877
lft1	lefty1	0.863
ntla	no tail a	0.816	Mouse
fbn2b	fibrillin 2b	0.815
fn1	fibronectin 1	0.801
tbx16	T-box gene 16	0.773
sox32	SRY-box containing gene 32	0.755
smo	smoothened homolog (Drosophila)	0.624
cdh2	cadherin 2, neuronal	0.596
dmd	dystrophin	0.551
dzip1	DAZ interacting protein 1	0.540
col27a1a	collagen, type XXVII, alpha 1a	0.528
spns2	spinster homolog 2 (Drosophila)	0.506
oep	one-eyed pinhead	0.496
admp	anti-dorsalizing morphogenic protein	0.485
gpc4	glypican 4	0.446
wnt5b	wingless-type MMTV integration site family, member 5b	0.400
bmpr2a	bone morphogenetic protein receptor, type II a (serine/threonine kinase)	0.375
dld	deltaD	0.363
gli1	GLI-Kruppel family member 1	0.341	Mouse
cxcr4a	chemokine (C-X-C motif) receptor 4a	0.321
nog1	noggin 1	0.317	Mouse
lft2	lefty2	0.314
wnt11	wingless-type MMTV integration site family, member 11	0.314
dkk1b	dickkopf 1b	0.308
lama5	laminin, alpha 5	0.250
mmp15b	matrix metallopeptidase 15b	0.227
ccm2	cerebral cavernous malformation 2	0.220
tbx24	T-box 24	0.201
hapln1b	hyaluronan and proteoglycan link protein 1b	0.170
bmpr2b	bone morphogenetic protein receptor, type II b (serine/threonine kinase)	0.166
lrrc6	leucine rich repeat containing 6	0.165
cdx4	caudal type homeo box transcription factor 4	0.159
lama2	laminin, alpha 2	0.150
vent	ventral expressed homeobox	0.148
dact2	dapper homolog 2, antagonist of beta-catenin (xenopus)	0.148
bon	bonnie and clyde	0.137
znf148	zinc finger protein 148	0.132
fgf3	fibroblast growth factor 3	0.118
boc	brother of CDO	0.109
bmp1a	bone morphogenetic protein 1a	0.109
lamb2	laminin, beta 2 (laminin S)	0.106	Zebrafish
og9x	OG9 homeobox gene	0.106
smad9	MAD homolog 9 (Drosophila)	0.105
tbx1	T-box 1	0.104
nanos3	nanos homolog 3	0.102
otx1a	orthodenticle homolog 1a	0.083
bmp2b	bone morphogenetic protein 2b	0.079
nog3	noggin 3	0.077
hsp90a.1	heat shock protein 90-alpha 1	0.076
slit3	slit (Drosophila) homolog 3	0.076
col2a1a	collagen type II, alpha-1a	0.072
tll1	tolloid-like 1	0.069
foxd5	forkhead box D5	0.069
si:ch211-173b8.2	si:ch211-173b8.2	0.069
disc1	disrupted in schizophrenia 1	0.066
hmgcrb	3-hydroxy-3-methylglutaryl-Coenzyme A reductase b	0.065
rpz	rapunzel	0.063
tnnt2a	troponin T2a, cardiac	0.058
tbx2a	T-box gene 2a	0.058
col27a1b	collagen, type XXVII, alpha 1b	0.056
ptch2	patched 2	0.056
mib	mind bomb	0.052
chsy1	chondroitin sulfate synthase 1	0.050
sox19b	SRY-box containing gene 19b	0.048
gli2a	GLI-Kruppel family member GLI2a	0.047	Mouse
chpf	chondroitin polymerizing factor	0.045
her7	hairy and enhancer of split related-7	0.045
twist1a	twist1a	0.045
frem1a	Fras1 related extracellular matrix 1a	0.044
wu:fc18d04	wu:fc18d04	0.042
lamc3	laminin, gamma 3	0.041
pard6gb	par-6 partitioning defective 6 homolog gamma B (C. elegans)	0.041
sulf1	sulfatase 1	0.041
cmn	calymmin	0.040
foxh1	forkhead box H1	0.039
plxnd1	plexin D1	0.039
col5a3b	collagen type V alpha-3b	0.038
foxi1	forkhead box I1	0.037
hapln1a	hyaluronan and proteoglycan link protein 1a	0.037
itga3b	integrin, alpha 3b	0.034
chrnd	cholinergic receptor, nicotinic, delta polypeptide	0.034
zgc:194470	zgc:194470	0.033
prickle1a	prickle-like 1 (Drosophila) a	0.032
pcdh8	protocadherin 8	0.032
pou5f1	POU domain, class 5, transcription factor 1	0.031
shdb	Src homology 2 domain containing transforming protein D, b	0.031
col5a3	collagen, type V, alpha 3	0.030
apc	adenomatosis polyposis coli	0.030
foxa2	forkhead box A2	0.030
plod2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.029
twist2	twist2	0.028
sdc2	syndecan 2	0.028
szl	sizzled	0.028
krit1	KRIT1, ankyrin repeat containing	0.027
cyr61	cysteine-rich, angiogenic inducer, 61	0.027
lama4	laminin, alpha 4	0.026
plod1a	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1a	0.026
hmcn1	hemicentin 1	0.026
jam2b	junctional adhesion molecule 2b	0.025
and2	actinodin2	0.025
stab2	stabilin 2	0.024
myst3	MYST histone acetyltransferase (monocytic leukemia) 3	0.024
frzb	frizzled-related protein	0.023
mapta	microtubule-associated protein tau a	0.022
smyd1b	SET and MYND domain containing 1b	0.022
emilin3a	elastin microfibril interfacer 3a	0.022
zgc:103467	myosin, light chain 9, regulatory	0.021
cx36.7	connexin 36.7	0.021
bmp4	bone morphogenetic protein 4	0.021
fli1b	friend leukemia integration 1b	0.020
bmp7a	bone morphogenetic protein 7a	0.020
cftr	cystic fibrosis transmembrane conductance regulator, ATP-binding cassette (sub-family C, member 7)	0.020
vangl2	vang-like 2 (van gogh, Drosophila)	0.020
aplnra	apelin receptor a	0.020
zgc:85838	zgc:85838	0.020
furina	furin (paired basic amino acid cleaving enzyme) a	0.019
hand2	heart and neural crest derivatives expressed transcript 2	0.019
hspa12b	heat shock protein 12B	0.019
fzd5	frizzled homolog 5	0.019
gata5	GATA-binding protein 5	0.019
slc25a37	solute carrier family 25, member 37	0.019
dlc	deltaC	0.018
ef1	ETS-related factor1	0.017
frem2a	Fras1 related extracellular matrix protein 2a	0.017
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.017
unc45b	unc-45 homolog B (C. elegans)	0.017
LOC556849	ectonucleoside triphosphate diphosphohydrolase 5-like	0.017
edar	ectodysplasin A receptor	0.016
scxa	scleraxis homolog A (mouse)	0.016
ntd5	ntl-dependent gene 5	0.016
tbx2b	T-box 2b	0.015
zgc:85866	zgc:85866	0.015
si:dkey-223d9.2	si:dkey-223d9.2	0.015
jam3b	junctional adhesion molecule 3b	0.015
jam2a	junctional adhesion molecule 2a	0.014
anxa11a	annexin A11a	0.014
lama1	laminin, alpha 1	0.014	Zebrafish
cebpd	CCAAT/enhancer binding protein (C/EBP), delta	0.014
mxtx2	mix-type homeobox gene 2	0.014
msxd	muscle segment homeobox D	0.014
bmpr1ab	bone morphogenetic protein receptor, type 1ab	0.014
gsna	gelsolin a	0.014
lrig3	leucine-rich repeats and immunoglobulin-like domains 3	0.014
si:ch211-279m15.1	si:ch211-279m15.1	0.014
sox17	SRY-box containing gene 17	0.014
spon2a	spondin 2a, extracellular matrix protein	0.013
hes6	hairy and enhancer of split 6 (Drosophila)	0.013
ndr1	nodal-related 1	0.013	Zebrafish
flncb	filamin C, gamma b (actin binding protein 280)	0.013
nkx3.2	NK3 homeobox 2	0.012
suv39h1a	suppressor of variegation 3-9 homolog 1a	0.012
mpp5a	membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a)	0.012
scn4aa	sodium channel, voltage-gated, type IV, alpha, a	0.012
mgp	matrix Gla protein	0.012
scinla	scinderin like a	0.012
wu:fb16h09	wu:fb16h09	0.012
myf6	myogenic factor 6	0.012
id:ibd5051	id:ibd5051	0.012
prkci	protein kinase C, iota	0.012
smad1	MAD homolog 1 (Drosophila)	0.011
smtnl	smoothelin, like	0.011
lmo7a	LIM domain only 7a	0.011
enpp1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.011
utx	ubiquitously transcribed tetratricopeptide repeat, X chromosome	0.011
ehd2	EH-domain containing 2	0.011
dag1	dystroglycan 1	0.011
jun	jun proto-oncogene	0.011
ihhb	Indian hedgehog homolog b	0.011
nog2	noggin 2	0.011
wtip	Wilms tumor 1 interacting protein	0.011
evx2	even-skipped homeobox 2	0.011
bmper	BMP binding endothelial regulator	0.011
calua	calumenin a	0.011
stat1b	signal transducer and activator of transcription 1b	0.011
spon2b	spondin 2b, extracellular matrix protein	0.011
rltpr	RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing	0.011
and3	actinodin3	0.010
pdgfaa	platelet-derived growth factor alpha a	0.010
vox	ventral homeobox	0.010
yap1	Yes-associated protein 1	0.010
col15a1a	collagen, type XV, alpha 1a	0.010
zgc:136894	zgc:136894	0.010
six4a	sine oculis homeobox homolog 4a	0.010
bmpr1aa	bone morphogenetic protein receptor, type 1aa	0.010	Zebrafish
si:xx-bac7cse.2	si:xx-bac7cse.2	0.010
alpi	alkaline phosphatase, intestinal	0.010