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Danio rerio

14 genes annotated in zebrafish

regulation of immune response

Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.

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Known genes in the process in zebrafish Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of immune response"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of immune response" (in gray)

Name	Description	Probability	Func Analog Organism
grna	granulin a	0.843
wnt8a	wingless-type MMTV integration site family, member 8a	0.449
gata6	GATA-binding protein 6	0.352
LOC566708	FL cytokine receptor-like	0.330
tlr21	toll-like receptor 21	0.330
tlr3	toll-like receptor 3	0.289	Human Fly
ripk2	receptor-interacting serine-threonine kinase 2	0.266
stc1l	stanniocalcin 1, like	0.201
cdh1	cadherin 1, epithelial	0.195
spi1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.182
LOC100151531	zinc finger protein Gfi-1b-like	0.176
ef1a	elongation factor 1-alpha	0.173
nod1	nucleotide-binding oligomerization domain containing 1	0.151
bmp2b	bone morphogenetic protein 2b	0.144
c3b	complement component c3b	0.138
atf3	activating transcription factor 3	0.135
tlr9	toll-like receptor 9	0.127
fabp11a	fatty acid binding protein 11a	0.106
epas1b	endothelial PAS domain protein 1b	0.105
shbg	sex hormone binding globulin	0.100
irf11	interferon regulatory factor 11	0.096
LOC557072	caspase recruitment domain-containing protein 11-like	0.094
epor	erythropoietin receptor	0.086
rarga	retinoic acid receptor gamma a	0.081
mafba	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	0.080
hbbe1.1	hemoglobin beta embryonic-1.1	0.080
si:ch211-212m21.5	si:ch211-212m21.5	0.079	Human
LOC100000934	hypothetical protein LOC100000934	0.079
boc	brother of CDO	0.079
desma	desmin a	0.078
stat1b	signal transducer and activator of transcription 1b	0.076
yes1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.075
dharma	dharma	0.072
col12a1	collagen, type XII, alpha 1	0.067
tbx5b	T-box 5b	0.065
si:dkey-27i16.2	si:dkey-27i16.2	0.065
sh3gl1b	SH3-domain GRB2-like 1b	0.064
pglyrp5	peptidoglycan recognition protein 5	0.061
wu:fi38e01	wu:fi38e01	0.060
fes	feline sarcoma oncogene	0.060
mmp9	matrix metalloproteinase 9	0.058
rorca	RAR-related orphan receptor C a	0.058
sh3gl1a	SH3-domain GRB2-like 1a	0.057
fsta	follistatin a	0.056
efnb3b	ephrin B3b	0.055
pth1a	parathyroid hormone 1a	0.055
tlr2	toll-like receptor 2	0.055	Mouse
lsm14b	LSM14B, SCD6 homolog B (S. cerevisiae)	0.054
foxi3a	forkhead box I3a	0.054
tcf7l2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.054
irak4	interleukin-1 receptor-associated kinase 4	0.053
adipoql	adiponectin, C1Q and collagen domain containing, like	0.051	Zebrafish
nfkbiaa	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a	0.051	Mouse Fly
calcrla	calcitonin receptor-like a	0.048
rhag	Rhesus blood group-associated glycoprotein	0.048
nfkbiab	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b	0.048	Mouse Fly
nos2a	nitric oxide synthase 2a, inducible	0.046
lndc1	ly6/neurotoxin domain containing 1	0.045
caspa	caspase a	0.044
vwf	von Willebrand factor	0.044
ifnphi1	interferon phi 1	0.044
jak1	Janus kinase 1	0.044
nipblb	novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila)	0.043
dnmt4	DNA (cytosine-5-)-methyltransferase 4	0.042
cp	ceruloplasmin	0.041
tnfb	tumor necrosis factor b (TNF superfamily, member 2)	0.041	Mouse
wu:fj82b07	wu:fj82b07	0.040
pou3f3b	POU class 3 homeobox 3b	0.039
ighm	immunoglobulin heavy constant mu and immunoglobulin heavy constant mu	0.038
tnfsf10l2	tumor necrosis factor (ligand) superfamily, member 10 like 2	0.037
shha	sonic hedgehog a	0.037
foxi2	forkhead box I2	0.036
slc4a4b	solute carrier family 4, sodium bicarbonate cotransporter, member 4b	0.036
zgc:161979	zgc:161979	0.034
znf148	zinc finger protein 148	0.033
ezr	ezrin	0.033
c1qc	complement component 1, q subcomponent, C chain	0.032
tlr18	toll-like receptor 18	0.032
perp	PERP, TP53 apoptosis effector	0.032
mitfa	microphthalmia-associated transcription factor a	0.032
ets1a	v-ets erythroblastosis virus E26 oncogene homolog 1a	0.032
copa	coatomer protein complex, subunit alpha	0.031
tp63	tumor protein p63	0.031
c1qb	complement component 1, q subcomponent, B chain	0.031
zgc:66455	zgc:66455	0.030
ythdf1	YTH domain family, member 1	0.030
hs6st3	heparan sulfate 6-O-sulfotransferase 3	0.030
si:dkeyp-110g5.2	si:dkeyp-110g5.2	0.029	Human
mmp14a	matrix metalloproteinase 14a (membrane-inserted)	0.029
hspa4b	heat shock protein 4b	0.029
mpx	myeloid-specific peroxidase	0.029
frzb	frizzled-related protein	0.029
ptpn11a	protein tyrosine phosphatase, non-receptor type 11, a	0.028
pax5	paired box gene 5	0.028
rag2	recombination activating gene 2	0.027
LOC100330224	fatty acid binding protein 1b-like	0.027
gclc	glutamate-cysteine ligase, catalytic subunit	0.027
cd40lg	CD40 ligand	0.027
erbb3b	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b	0.026
rhcgl1	Rhesus blood group, C glycoprotein, like 1	0.026
kcnh2	potassium voltage-gated channel, subfamily H (eag-related), member 2	0.026
cd247l	CD247 antigen like	0.026
cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.026
anxa1a	annexin A1a	0.025
gata1a	GATA binding protein 1a	0.025
cyp3a65	cytochrome P450, family 3, subfamily A, polypeptide 65	0.025
elk4	ELK4, ETS-domain protein	0.025
zp2.2	zona pellucida glycoprotein 2.2	0.025
fam20b	family with sequence similarity 20, member B (H. sapiens)	0.025
arl4ab	ADP-ribosylation factor-like 4ab	0.025
dbx1a	developing brain homeobox 1a	0.024
ptpra	protein tyrosine phosphatase, receptor type, A	0.024
hddc3	HD domain containing 3	0.024
wasa	Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a	0.024
nkx2.5	NK2 transcription factor related 5	0.024
ecrg4a	esophageal cancer related gene 4a	0.023
ifng1-2	interferon, gamma 1-2	0.023
lipc	lipase, hepatic	0.023
ikzf1	IKAROS family zinc finger 1 (Ikaros)	0.022
adipor2	adiponectin receptor 2	0.022
insrb	insulin receptor b	0.022
zgc:56005	zgc:56005	0.022
rpl37	ribosomal protein L37	0.022
meis1	myeloid ecotropic viral integration 1	0.022
mxra8a	matrix-remodelling associated 8a	0.021
cyt1	type I cytokeratin, enveloping layer	0.021
fgfrl1b	fibroblast growth factor receptor-like 1b	0.021
paqr7b	progestin and adipoQ receptor family member VII, b	0.020
crip2	cysteine-rich protein 2	0.020
tnfa	tumor necrosis factor a (TNF superfamily, member 2)	0.020	Mouse
ca15a	carbonic anhydrase XV a	0.020
egr1	early growth response 1	0.020
rab11fip4a	RAB11 family interacting protein 4 (class II) a	0.020
lft1	lefty1	0.020
elovl4a	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4a	0.020
dcn	decorin	0.020
pdcd2	programmed cell death 2	0.019
st8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	0.019
amotl2a	angiomotin like 2a	0.019
naa15b	N(alpha)-acetyltransferase 15, NatA auxiliary subunit b	0.019
socs3a	suppressor of cytokine signaling 3a	0.019	Zebrafish
nkd2	naked cuticle homolog 2 and naked 2a	0.019
zgc:111868	zgc:111868	0.019
pias4a	protein inhibitor of activated STAT, 4a	0.019
vdrb	vitamin D receptor b	0.018
illr1	immune-related, lectin-like receptor 1	0.018	Zebrafish
acvr2a	activin receptor IIa	0.018
hpx	hemopexin	0.018	Mouse
myh11a	myosin, heavy polypeptide 11, smooth muscle a	0.018
fcho2	FCH domain only 2	0.018
tbx21	T-box 21	0.018
tbpl2	TATA box binding protein like 2	0.018
piwil1	piwi-like 1 (Drosophila)	0.018	Fly
LOC100003330	melanocortin-2 receptor accessory protein 2-like	0.017
si:dkey-223d9.2	si:dkey-223d9.2	0.017
nr3c1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.017
hapln1b	hyaluronan and proteoglycan link protein 1b	0.017
gdf11	growth differentiation factor 11	0.017
ikbkg	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.017
pdlim1	PDZ and LIM domain 1 (elfin)	0.017
ahsg	alpha-2-HS-glycoprotein	0.017
tfe3a	transcription factor binding to IGHM enhancer 3a	0.017
proc	protein C (inactivator of coagulation factors Va and VIIIa)	0.017
fos	v-fos FBJ murine osteosarcoma viral oncogene homolog	0.017
ovol1	ovo-like 1 (Drosophila)	0.016
sb:eu1555	sb:eu1555	0.016
npy7r	neuropeptide Y receptor Y7	0.016
crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	0.016
eomesa	eomesodermin homolog a	0.016
foxp3a	forkhead box P3a	0.016	Mouse
sfrp5	secreted frizzled-related protein 5	0.016
sema3aa	semaphorin 3aa	0.016
pea3	ETS-domain transcription factor pea3	0.016
elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	0.016
vipr2	vasoactive intestinal peptide receptor 2	0.016
adipor1b	adiponectin receptor 1b	0.016
tfe3b	transcription factor binding to IGHM enhancer 3b	0.016
zgc:64105	zgc:64105	0.016
zgc:136878	zgc:136878	0.015
itga2b	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)	0.015
fxr2	fragile X mental retardation, autosomal homolog 2	0.015
ecscr	endothelial cell-specific chemotaxis regulator	0.015
il22	interleukin 22	0.015
zgc:103710	zgc:103710	0.015
cdh4	cadherin 4, retinal	0.015
gtf3ab	general transcription factor IIIA, b	0.015
tgfb3	transforming growth factor, beta 3	0.015	Human
erbb3a	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3a	0.015
xrcc5	X-ray repair complementing defective repair in Chinese hamster cells 5	0.015
plagl2	pleiomorphic adenoma gene-like 2	0.015
zgc:64051	zgc:64051	0.015
si:dkey-88l16.3	si:dkey-88l16.3	0.015
wu:fi42e03	wu:fi42e03	0.015
fcer1g	Fc receptor, IgE, high affinity I, gamma polypeptide	0.015
smoc2	secreted modular calcium binding protein 2	0.015
dnmt6	DNA (cytosine-5-)-methyltransferase 6	0.015
f5	coagulation factor V	0.014
cxc46	CXC chemokine 46	0.014
ahr1a	aryl hydrocarbon receptor 1a	0.014
junb	jun B proto-oncogene	0.014
ip6k2	inositol hexaphosphate kinase 2	0.014
lbr	lamin B receptor	0.014
cntn2	contactin 2	0.014
vcana	versican a	0.014
vtg4	vitellogenin 4	0.014
tlr20a	toll-like receptor 20a	0.014
epha4b	eph receptor A4b	0.014
axin2	axin 2 (conductin, axil)	0.014
prrx1a	paired related homeobox 1a	0.014
LOC100333772	zona pellucida sperm-binding protein 4-like	0.014
nadl1.2	neural adhesion molecule L1.2	0.014
calcr	calcitonin receptor	0.014
atp1b1a	ATPase, Na+/K+ transporting, beta 1a polypeptide	0.014
si:dkey-236e20.2	si:dkey-236e20.2	0.014
birc5b	baculoviral IAP repeat-containing 5B	0.013
mst1rb	macrophage stimulating 1 receptor (c-met-related tyrosine kinase), b	0.013
dhfr	dihydrofolate reductase	0.013
il6st	interleukin 6 signal transducer	0.013
ddx41	DEAD (Asp-Glu-Ala-Asp) box polypeptide 41	0.013
igf1	insulin-like growth factor 1	0.013
ptena	phosphatase and tensin homolog A	0.013
tlr4bb	toll-like receptor 4b, duplicate b	0.013	Human Mouse
fibin	fin bud initiation factor	0.013
trim25	tripartite motif-containing 25	0.013
traf6	TNF receptor-associated factor 6	0.013	Human
tert	telomerase reverse transcriptase	0.013
slc30a7	solute carrier family 30 (zinc transporter), member 7	0.013
hmx1	H6 homeo box 1	0.013
fgfr2	fibroblast growth factor receptor 2	0.013	Fly
emx2	empty spiracles homeobox 2	0.013
trpm7	transient receptor potential cation channel, subfamily M, member 7	0.013
waca	WW domain containing adaptor with coiled-coil a	0.013
il6r	interleukin 6 receptor	0.013
tmem144b	transmembrane protein 144b	0.013
cd209	CD209 molecule	0.012	Zebrafish
rtf1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.012
LOC793458	peptide Y-like	0.012
nfe2	nuclear factor, erythroid-derived 2	0.012
cldnd	claudin d	0.012
il8	interleukin 8	0.012
tm9sf2	transmembrane 9 superfamily member 2	0.012
cfl1	cofilin 1 (non-muscle)	0.012
slc4a2b	solute carrier family 4, anion exchanger, member 2b	0.012
acvr1l	activin A receptor, type I like	0.012	Fly
zgc:64115	zgc:64115	0.012
rrp12	ribosomal RNA processing 12 homolog (S. cerevisiae)	0.012
zp3a.1	zona pellucida glycoprotein 3a.1	0.012	Human
tpsn	tapasin	0.012
gata4	GATA-binding protein 4	0.012	Fly
LOC100003514	protein kinase C alpha type-like	0.012
fxyd1	FXYD domain containing ion transport regulator 1 (phospholemman)	0.012
gadd45aa	growth arrest and DNA-damage-inducible, alpha, a	0.012
tbx16	T-box gene 16	0.012
gadd45ba	growth arrest and DNA-damage-inducible, beta a	0.012
cbfb	core-binding factor, beta subunit	0.012
fli1b	friend leukemia integration 1b	0.012
tnnt2a	troponin T2a, cardiac	0.012
adrb2a	adrenergic receptor, beta 2a	0.012
itgb3b	integrin beta 3b	0.012
pycard	PYD and CARD domain containing	0.012	Human Mouse
rnasel1	ribonuclease like 1	0.012
slc4a1b	solute carrier family 4, anion exchanger, member 1b	0.012
zgc:85866	zgc:85866	0.011
hsd17b3	hydroxysteroid (17-beta) dehydrogenase 3	0.011
zgc:66449	zgc:66449	0.011
ppm1ab	protein phosphatase, Mg2+/Mn2+ dependent, 1Ab	0.011
st8sia3	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3	0.011
isg15	ISG15 ubiquitin-like modifier	0.011
irf9	interferon regulatory factor 9	0.011
smoc1	SPARC related modular calcium binding 1	0.011
si:ch211-284e13.2	si:ch211-284e13.2	0.011
vcp	valosin containing protein	0.011
kpna3	karyopherin (importin) alpha 3	0.011
tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.011
c1qa	complement component 1, q subcomponent, A chain	0.011
socs1	suppressor of cytokine signaling 1	0.011
cdc34b	cell division cycle 34 homolog (S. cerevisiae) b	0.011
acp5b	acid phosphatase 5b, tartrate resistant	0.011
ntla	no tail a	0.010
carm1	coactivator-associated arginine methyltransferase 1	0.010
atp6v1al	ATPase, H+ transporting, lysosomal V1 subunit A, like	0.010
trpv1	transient receptor potential cation channel subfamily V member 1	0.010
rel	v-rel reticuloendotheliosis viral oncogene homolog	0.010
eya2	eyes absent homolog 2 (Drosophila)	0.010
limk1	LIM domain kinase 1	0.010
psmb9a	proteasome (prosome, macropain) subunit, beta type, 9a	0.010
nitr13	novel immune-type receptor 13	0.010
atp1b2a	ATPase, Na+/K+ transporting, beta 2a polypeptide	0.010
ppp2r5ea	protein phosphatase 2, regulatory subunit B', epsilon isoform a	0.010
cav1	caveolin 1	0.010
zgc:92880	zgc:92880	0.010
unc5c	unc-5 homolog C (C. elegans)	0.010
cpox	coproporphyrinogen oxidase	0.010
mtp	microsomal triglyceride transfer protein	0.010
zgc:110340	zgc:110340	0.010
LOC100332505	hypothetical protein LOC100332505	0.010
elovl1a	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1a	0.010
zgc:64114	zgc:64114	0.010