The network for 'regulation of leukocyte migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of leukocyte migration

Any process that modulates the frequency, rate, or extent of leukocyte migration.

Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 0.993
IL8 interleukin 8 0.990
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.989
CCL5 chemokine (C-C motif) ligand 5 0.983
S100A6 S100 calcium binding protein A6 0.973
CXCL9 chemokine (C-X-C motif) ligand 9 0.973
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.964
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.960
CXCL10 chemokine (C-X-C motif) ligand 10 0.951
VEGFA vascular endothelial growth factor A 0.945
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.940
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.927
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.916
S100B S100 calcium binding protein B 0.910
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.906
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.906
PLAU plasminogen activator, urokinase 0.889
PLAUR plasminogen activator, urokinase receptor 0.887
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.887
CXCL3 chemokine (C-X-C motif) ligand 3 0.876
HOXB5 homeobox B5 0.876
S100A16 S100 calcium binding protein A16 0.857
IL1B interleukin 1, beta 0.831
CCL19 chemokine (C-C motif) ligand 19 0.817
CCL4 chemokine (C-C motif) ligand 4 0.813
CXCL2 chemokine (C-X-C motif) ligand 2 0.805
CCL20 chemokine (C-C motif) ligand 20 0.801
IL2RB interleukin 2 receptor, beta 0.766
CD44 CD44 molecule (Indian blood group) 0.764
CCR1 chemokine (C-C motif) receptor 1 0.761
S100A1 S100 calcium binding protein A1 0.760
CCL2 chemokine (C-C motif) ligand 2 0.749
TIMP1 TIMP metallopeptidase inhibitor 1 0.748
HCK hemopoietic cell kinase 0.739
CD163 CD163 molecule 0.739
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.734
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.717
S100A14 S100 calcium binding protein A14 0.708
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.702
IL6 interleukin 6 (interferon, beta 2) 0.701
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.658
EZR ezrin 0.654
CCL8 chemokine (C-C motif) ligand 8 0.635
APOE apolipoprotein E 0.624
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.609
THBS1 thrombospondin 1 0.599
CCL7 chemokine (C-C motif) ligand 7 0.596
COL1A1 collagen, type I, alpha 1 0.576
AXL AXL receptor tyrosine kinase 0.572
IL10 interleukin 10 0.558
CCR7 chemokine (C-C motif) receptor 7 0.539
FYN FYN oncogene related to SRC, FGR, YES 0.536
EMP3 epithelial membrane protein 3 0.534
LAIR1 leukocyte-associated immunoglobulin-like receptor 1 0.525
IFNG interferon, gamma 0.518
ABI2 abl-interactor 2 0.510
NRP1 neuropilin 1 0.500
PTGIR prostaglandin I2 (prostacyclin) receptor (IP) 0.495
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.490
TNF tumor necrosis factor 0.485
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.484
DPP4 dipeptidyl-peptidase 4 0.474
CCL13 chemokine (C-C motif) ligand 13 0.467
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.462
PLEK pleckstrin 0.439
VCAM1 vascular cell adhesion molecule 1 0.437
BIRC3 baculoviral IAP repeat containing 3 0.429
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.428
CXCL5 chemokine (C-X-C motif) ligand 5 0.426
CXCR4 chemokine (C-X-C motif) receptor 4 0.400
ICAM1 intercellular adhesion molecule 1 0.400
MEFV Mediterranean fever 0.391
SELPLG selectin P ligand 0.381
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.363
CXCL11 chemokine (C-X-C motif) ligand 11 0.358
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.356
CXCL13 chemokine (C-X-C motif) ligand 13 0.345
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.343
PLAT plasminogen activator, tissue 0.341
S100A11 S100 calcium binding protein A11 0.338
SCHIP1 schwannomin interacting protein 1 0.338
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.332
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.331
FN1 fibronectin 1 0.320
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.318
TFF1 trefoil factor 1 0.317
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.305
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.302
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) 0.289
C5AR1 complement component 5a receptor 1 0.285
RHOC ras homolog gene family, member C 0.280
TBXA2R thromboxane A2 receptor 0.277
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.271
IL2RG interleukin 2 receptor, gamma 0.259
CFH complement factor H 0.253
HOXA7 homeobox A7 0.251
PDCD6IP programmed cell death 6 interacting protein 0.250
AQP9 aquaporin 9 0.250
SELL selectin L 0.250
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.247
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
kdrl kinase insert domain receptor like 0.968
nod1 nucleotide-binding oligomerization domain containing 1 0.157
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.095
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.086
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.086
lyz lysozyme 0.076
ptprsa protein tyrosine phosphatase, receptor type, s, a 0.076
tie2 endothelium-specific receptor tyrosine kinase 2 0.063
card9 caspase recruitment domain family, member 9 0.063
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.053
erg v-ets erythroblastosis virus E26 oncogene like (avian) 0.053
efnb2a ephrin B2a 0.051
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.050
cdh5 cadherin 5 0.045
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.044
mmp9 matrix metalloproteinase 9 0.043
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.038
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.038
mmp2 matrix metalloproteinase 2 0.037
si:dkey-236e20.2 si:dkey-236e20.2 0.033
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.030
col12a1 collagen, type XII, alpha 1 0.030
st8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 0.030
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.030
zgc:101614 zgc:101614 0.029
vegfc vascular endothelial growth factor c 0.029
pak2a p21 (CDKN1A)-activated kinase 2a 0.027
postn periostin, osteoblast specific factor 0.027
ctsc cathepsin C 0.026
coro1a coronin, actin binding protein, 1A 0.025
btk Bruton agammaglobulinemia tyrosine kinase 0.025
si:ch211-212m21.5 si:ch211-212m21.5 0.025
lta4h leukotriene A4 hydrolase 0.025
nrp2b neuropilin 2b 0.024
col6a3 collagen, type VI, alpha 3 0.023
dopey1 dopey family member 1 0.023
plxnd1 plexin D1 0.023
ntla no tail a 0.023
ptprc protein tyrosine phosphatase, receptor type, C 0.022
mmp13a matrix metalloproteinase 13a 0.022
dll4 delta-like 4 (Drosophila) 0.021
dzip1 DAZ interacting protein 1 0.021
runx3 runt-related transcription factor 3 0.020
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.019
agtr2 angiotensin II receptor, type 2 0.019
atp6ap1 ATPase, H+ transporting, lysosomal accessory protein 1 0.019
irf8 interferon regulatory factor 8 0.018
ncf1 neutrophil cytosolic factor 1 0.018
cbfb core-binding factor, beta subunit 0.018
im:7154036 im:7154036 0.017
tpm4 tropomyosin 4 0.017
tll1 tolloid-like 1 0.017
si:ch211-235f6.2 si:ch211-235f6.2 0.017
meox1 mesenchyme homeobox 1 0.017
kitlga kit ligand a 0.017
epas1b endothelial PAS domain protein 1b 0.016
hspg2 heparan sulfate proteoglycan 2 0.016
col5a1 procollagen, type V, alpha 1 0.016
rhag Rhesus blood group-associated glycoprotein 0.016
cyp24a1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.016
clic2 chloride intracellular channel 2 0.015
esama endothelial cell adhesion molecule a 0.015
ccbe1 collagen and calcium binding EGF domains 1 0.015
jam2a junctional adhesion molecule 2a 0.015
zgc:110010 zgc:110010 0.014
igfbp3 insulin-like growth factor binding protein 3 0.014
cdc42l cell division cycle 42, like 0.014
lgals3bpb lectin, galactoside-binding, soluble, 3 binding protein b 0.014
si:dkey-261h17.1 si:dkey-261h17.1 0.013
sp2 sp2 transcription factor 0.013
flncb filamin C, gamma b (actin binding protein 280) 0.013
tnfsf18 tumor necrosis factor (ligand) superfamily, member 18 0.013
ints6 integrator complex subunit 6 0.013
htra1a HtrA serine peptidase 1a 0.012
sla1 Src-like-adaptor 1 0.012
ccr6a chemokine (C-C motif) receptor 6a 0.012
clstn1 calsyntenin 1 0.012
gmfg glia maturation factor, gamma 0.012
si:dkeyp-104h9.6 si:dkeyp-104h9.6 0.012
wu:fj39b01 wu:fj39b01 0.012
gnb1a guanine nucleotide binding protein (G protein), beta polypeptide 1a 0.012
six1b sine oculis homeobox homolog 1b 0.011
ephb4a eph receptor B4a 0.011
fcer1gl Fc receptor, IgE, high affinity I, gamma polypeptide like 0.011
gpr182 G protein-coupled receptor 182 0.011
spred1 sprouty-related, EVH1 domain containing 1 0.011
fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.011
myd88 myeloid differentiation primary response gene (88) 0.011
mpx myeloid-specific peroxidase 0.011
adora2aa adenosine A2a receptor a 0.010
ccl25b chemokine (C-C motif) ligand 25b 0.010
dlc deltaC 0.010
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.010
si:dkey-12o15.1 si:dkey-12o15.1 0.010
hnf1a HNF1 homeobox a 0.010
ftsj FtsJ homolog 3 (E. coli) 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Cxcl10 chemokine (C-X-C motif) ligand 10 0.942
Ccl4 chemokine (C-C motif) ligand 4 0.894
Il1b interleukin 1 beta 0.741
Cd4 Cd4 molecule 0.690
Mmp3 matrix metallopeptidase 3 0.689
Ccl2 chemokine (C-C motif) ligand 2 0.654
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.628
Olr1500 olfactory receptor 1500 0.624
Cxcl2 chemokine (C-X-C motif) ligand 2 0.603
Il6 interleukin 6 0.459
Thbd thrombomodulin 0.400
RT1-Ba RT1 class II, locus Ba 0.380
Mmp10 matrix metallopeptidase 10 0.375
Ccl3 chemokine (C-C motif) ligand 3 0.365
Il8rb interleukin 8 receptor, beta 0.342
Il1rn interleukin 1 receptor antagonist 0.336
Serpine1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.325
Plau plasminogen activator, urokinase 0.298
Neurl3 neuralized homolog 3 (Drosophila) 0.262
Cd14 CD14 molecule 0.261
Fosl1 fos-like antigen 1 0.253
Hck hemopoietic cell kinase 0.248
Il1a interleukin 1 alpha 0.237
Adam2 ADAM metallopeptidase domain 2 0.234
Ptafr platelet-activating factor receptor 0.230
Calcrl calcitonin receptor-like 0.215
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.210
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.206
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.188
Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 0.170
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.148
Icam1 intercellular adhesion molecule 1 0.146
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.145
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.143
RT1-Da RT1 class II, locus Da 0.138
Reg3g regenerating islet-derived 3 gamma 0.136
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.134
Casp1 caspase 1 0.134
Cd44 Cd44 molecule 0.133
Ptprc protein tyrosine phosphatase, receptor type, C 0.132
Reg3b regenerating islet-derived 3 beta 0.129
Gzmb granzyme B 0.118
Cxcr4 chemokine (C-X-C motif) receptor 4 0.114
Myo1c myosin IC 0.114
Ctsj cathepsin J 0.114
Fgf2 fibroblast growth factor 2 0.113
Ccl20 chemokine (C-C motif) ligand 20 0.112
Olfml2b olfactomedin-like 2B 0.110
Mmp12 matrix metallopeptidase 12 0.108
Serpinb2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.107
Sell selectin L 0.106
Ccl11 chemokine (C-C motif) ligand 11 0.104
RT1-Bb RT1 class II, locus Bb 0.101
Cd8a CD8a molecule 0.098
Faslg Fas ligand (TNF superfamily, member 6) 0.098
Laptm5 lysosomal protein transmembrane 5 0.093
Tcrb T-cell receptor beta chain 0.092
Lepr leptin receptor 0.087
Olr1078 olfactory receptor 1078 0.087
Socs3 suppressor of cytokine signaling 3 0.085
Adora2a adenosine A2a receptor 0.082
Utrn utrophin 0.080
Col12a1 collagen, type XII, alpha 1 0.079
Slc30a2 solute carrier family 30 (zinc transporter), member 2 0.076
Crisp1 cysteine-rich secretory protein 1 0.075
Il2rg interleukin 2 receptor, gamma 0.075
Mrgprf MAS-related GPR, member F 0.072
LOC100360403 ATP-binding cassette, sub-family C, member 9-like 0.066
Ccl7 chemokine (C-C motif) ligand 7 0.065
Htr5b 5-hydroxytryptamine (serotonin) receptor 5B 0.063
Pth parathyroid hormone 0.060
Vip vasoactive intestinal peptide 0.060
Gzmk granzyme K 0.060
Egr2 early growth response 2 0.060
Kcna3 potassium voltage-gated channel, shaker-related subfamily, member 3 0.059
Ar androgen receptor 0.059
Mmp2 matrix metallopeptidase 2 0.058
Il1r2 interleukin 1 receptor, type II 0.058
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.058
Ccl5 chemokine (C-C motif) ligand 5 0.057
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.057
S1pr2 sphingosine-1-phosphate receptor 2 0.055
Cybb cytochrome b-245, beta polypeptide 0.055
Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.054
Dnase1l3 deoxyribonuclease 1-like 3 0.053
LOC100364854 similar to RIKEN cDNA A430107P09 gene-like 0.051
Slc5a1 solute carrier family 5 (sodium/glucose cotransporter), member 1 0.051
Figf c-fos induced growth factor 0.050
Avpr1b arginine vasopressin receptor 1B 0.050
Sycp1 synaptonemal complex protein 1 0.049
LOC100364485 mCG1051031-like 0.049
Clic4 chloride intracellular channel 4 0.049
Vcan versican 0.049
Ier3 immediate early response 3 0.048
Igsf6 immunoglobulin superfamily, member 6 0.048
Phex phosphate regulating endopeptidase homolog, X-linked 0.047
Il9r interleukin 9 receptor 0.047
Ednra endothelin receptor type A 0.046
Atxn1 ataxin 1 0.045
Atf3 activating transcription factor 3 0.045
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism