Process View
The network for 'regulation of branching involved in ureteric bud morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 1.000 | |
| NRP1 | neuropilin 1 | 1.000 | |
| FSTL1 | follistatin-like 1 | 1.000 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 1.000 | |
| ENG | endoglin | 0.999 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.995 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.994 | |
| PJA1 | praja ring finger 1 | 0.990 | |
| MAGED2 | melanoma antigen family D, 2 | 0.983 | |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.969 | |
| PGF | placental growth factor | 0.912 | |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.895 | |
| NKX2-1 | NK2 homeobox 1 | 0.877 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.805 | |
| TGFB3 | transforming growth factor, beta 3 | 0.770 | |
| BMP2 | bone morphogenetic protein 2 | 0.747 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.692 | |
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.654 | |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.568 | |
| THBS1 | thrombospondin 1 | 0.536 | |
| BMP7 | bone morphogenetic protein 7 | 0.533 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.469 | |
| HNF1A | HNF1 homeobox A | 0.364 | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.338 | |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.315 | |
| MDFI | MyoD family inhibitor | 0.307 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.304 | |
| BBS1 | Bardet-Biedl syndrome 1 | 0.230 | |
| TGFB2 | transforming growth factor, beta 2 | 0.205 | |
| CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 | 0.198 | |
| CD14 | CD14 molecule | 0.180 | |
| CLDN7 | claudin 7 | 0.164 | |
| COL2A1 | collagen, type II, alpha 1 | 0.163 | |
| NOG | noggin | 0.159 | |
| CLDN1 | claudin 1 | 0.148 | |
| PAX8 | paired box 8 | 0.144 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.137 | |
| NDNL2 | necdin-like 2 | 0.134 | |
| EYA2 | eyes absent homolog 2 (Drosophila) | 0.127 | |
| HOXA11 | homeobox A11 | 0.126 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.123 | |
| TGFBR3 | transforming growth factor, beta receptor III | 0.109 | |
| NOTCH1 | notch 1 | 0.102 | |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.102 | |
| BMP4 | bone morphogenetic protein 4 | 0.101 | |
| C5orf13 | chromosome 5 open reading frame 13 | 0.099 | |
| SIM2 | single-minded homolog 2 (Drosophila) | 0.099 | |
| FOXA2 | forkhead box A2 | 0.096 | |
| XIAP | X-linked inhibitor of apoptosis | 0.095 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.095 | |
| WNT7A | wingless-type MMTV integration site family, member 7A | 0.094 | |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.088 | |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.086 | |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.086 | |
| EFNA1 | ephrin-A1 | 0.078 | |
| SMAD7 | SMAD family member 7 | 0.078 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.076 | |
| HMGA2 | high mobility group AT-hook 2 | 0.074 | |
| HES2 | hairy and enhancer of split 2 (Drosophila) | 0.072 | |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.068 | |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | 0.067 | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.066 | |
| HOXB9 | homeobox B9 | 0.064 | |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter, creatine), member 8 | 0.063 | |
| CLU | clusterin | 0.062 | |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.062 | |
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.062 | |
| HOXB6 | homeobox B6 | 0.061 | |
| PAEP | progestagen-associated endometrial protein | 0.058 | |
| FOXF1 | forkhead box F1 | 0.057 | |
| INHBB | inhibin, beta B | 0.055 | |
| COPG2 | coatomer protein complex, subunit gamma 2 | 0.053 | |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.053 | |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | 0.052 | |
| HOXB3 | homeobox B3 | 0.050 | |
| FGF4 | fibroblast growth factor 4 | 0.050 | |
| PAX7 | paired box 7 | 0.048 | |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.047 | |
| AKNA | AT-hook transcription factor | 0.046 | |
| PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.046 | |
| STC2 | stanniocalcin 2 | 0.046 | |
| WT1 | Wilms tumor 1 | 0.045 | |
| NDRG1 | N-myc downstream regulated 1 | 0.043 | |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.042 | |
| ARRB1 | arrestin, beta 1 | 0.042 | |
| YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.041 | |
| HOXC8 | homeobox C8 | 0.041 | |
| TBCD | tubulin folding cofactor D | 0.040 | |
| MYOD1 | myogenic differentiation 1 | 0.040 | |
| CRYAB | crystallin, alpha B | 0.038 | |
| SSR1 | signal sequence receptor, alpha | 0.038 | |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 | 0.038 | |
| VTN | vitronectin | 0.038 | |
| LMX1B | LIM homeobox transcription factor 1, beta | 0.038 | |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.038 | |
| FST | follistatin | 0.037 | |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.037 | |
| THBS2 | thrombospondin 2 | 0.037 | |
| ELANE | elastase, neutrophil expressed | 0.036 | |
| FZD8 | frizzled homolog 8 (Drosophila) | 0.036 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Pax2 | paired box gene 2 | 1.000 | |
| Fgf8 | fibroblast growth factor 8 | 1.000 | |
| Pax3 | paired box gene 3 | 0.999 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.999 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.999 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.998 | |
| Rarg | retinoic acid receptor, gamma | 0.998 | |
| Msx1 | homeobox, msh-like 1 | 0.997 | |
| Foxc2 | forkhead box C2 | 0.996 | |
| Lhx1 | LIM homeobox protein 1 | 0.995 | |
| Foxc1 | forkhead box C1 | 0.992 | |
| Tbx1 | T-box 1 | 0.989 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.987 | |
| Hoxa3 | homeobox A3 | 0.987 | |
| Hoxa1 | homeobox A1 | 0.986 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.985 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.983 | |
| Fgf10 | fibroblast growth factor 10 | 0.978 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.978 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.976 | |
| Wt1 | Wilms tumor 1 homolog | 0.974 | |
| Hoxa2 | homeobox A2 | 0.967 | |
| Bmp4 | bone morphogenetic protein 4 | 0.965 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.961 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.958 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.955 | |
| Rarb | retinoic acid receptor, beta | 0.951 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.946 | |
| Pax8 | paired box gene 8 | 0.925 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.920 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.917 | |
| Hoxb3 | homeobox B3 | 0.916 | |
| Hoxd3 | homeobox D3 | 0.899 | |
| Nodal | nodal | 0.895 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.887 | |
| Hoxa10 | homeobox A10 | 0.878 | |
| Dlx5 | distal-less homeobox 5 | 0.869 | |
| Nog | noggin | 0.868 | |
| Prrx1 | paired related homeobox 1 | 0.859 | |
| Pax6 | paired box gene 6 | 0.827 | |
| Lhx3 | LIM homeobox protein 3 | 0.826 | |
| Hoxa5 | homeobox A5 | 0.815 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.811 | |
| Hoxd9 | homeobox D9 | 0.804 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.801 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.800 | |
| Agtr1a | angiotensin II receptor, type 1a | 0.798 | |
| Hoxd11 | homeobox D11 | 0.791 | |
| Sox2 | SRY-box containing gene 2 | 0.789 | |
| Bmp7 | bone morphogenetic protein 7 | 0.786 | |
| Hoxb5 | homeobox B5 | 0.785 | |
| Prrx2 | paired related homeobox 2 | 0.784 | |
| Chrd | chordin | 0.780 | |
| Hoxa4 | homeobox A4 | 0.779 | |
| Smo | smoothened homolog (Drosophila) | 0.778 | |
| Hoxc5 | homeobox C5 | 0.769 | |
| Sox7 | SRY-box containing gene 7 | 0.758 | |
| Ace | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.744 | |
| Sall4 | sal-like 4 (Drosophila) | 0.729 | |
| Tbx2 | T-box 2 | 0.726 | |
| Fgf3 | fibroblast growth factor 3 | 0.720 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.719 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.686 | |
| Hoxd4 | homeobox D4 | 0.684 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.682 | |
| Hoxa11 | homeobox A11 | 0.673 | |
| Pax9 | paired box gene 9 | 0.670 | |
| Hoxb6 | homeobox B6 | 0.663 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.638 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.603 | |
| Bnc1 | basonuclin 1 | 0.601 | |
| T | brachyury | 0.593 | |
| Hoxc4 | homeobox C4 | 0.575 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.562 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.543 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.541 | |
| Sall3 | sal-like 3 (Drosophila) | 0.529 | |
| Foxf2 | forkhead box F2 | 0.520 | |
| Ednra | endothelin receptor type A | 0.517 | |
| Hoxc8 | homeobox C8 | 0.511 | |
| Meox2 | mesenchyme homeobox 2 | 0.500 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.494 | |
| Flt4 | FMS-like tyrosine kinase 4 | 0.490 | |
| Foxd2 | forkhead box D2 | 0.477 | |
| Msx2 | homeobox, msh-like 2 | 0.475 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.444 | |
| En1 | engrailed 1 | 0.439 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.424 | |
| Foxf1a | forkhead box F1a | 0.421 | |
| Hoxa9 | homeobox A9 | 0.404 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.398 | |
| Alx4 | aristaless-like homeobox 4 | 0.392 | |
| Tcf21 | transcription factor 21 | 0.385 | |
| Rara | retinoic acid receptor, alpha | 0.373 | |
| Gsc | goosecoid homeobox | 0.373 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.370 | |
| Lmx1b | LIM homeobox transcription factor 1 beta | 0.363 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.356 | |
| Hoxb2 | homeobox B2 | 0.347 |