IMP
Process View
The network for 'mitral valve development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
mitral valve development
The progression of the mitral valve over time, from its formation to the mature structure.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Gata4 | GATA binding protein 4 | 1.000 | |
| Sox9 | SRY-box containing gene 9 | 0.999 | |
| Pax3 | paired box gene 3 | 0.998 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.997 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.997 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.996 | |
| Ntf3 | neurotrophin 3 | 0.996 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.996 | |
| Smo | smoothened homolog (Drosophila) | 0.995 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.994 | |
| Fgf8 | fibroblast growth factor 8 | 0.993 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.992 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.990 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.977 | |
| Ephb2 | Eph receptor B2 | 0.976 | |
| Foxc2 | forkhead box C2 | 0.962 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.949 | |
| Bmp4 | bone morphogenetic protein 4 | 0.940 | |
| Shh | sonic hedgehog | 0.938 | |
| Foxc1 | forkhead box C1 | 0.929 | |
| Jag1 | jagged 1 | 0.927 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.921 | |
| Msx1 | homeobox, msh-like 1 | 0.909 | |
| Neurod1 | neurogenic differentiation 1 | 0.909 | |
| Prrx1 | paired related homeobox 1 | 0.904 | |
| Gata6 | GATA binding protein 6 | 0.891 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.886 | |
| Pax6 | paired box gene 6 | 0.848 | |
| Meox1 | mesenchyme homeobox 1 | 0.825 | |
| Gata1 | GATA binding protein 1 | 0.820 | |
| Fgf10 | fibroblast growth factor 10 | 0.820 | |
| Neurog3 | neurogenin 3 | 0.809 | |
| Ednra | endothelin receptor type A | 0.808 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.764 | |
| Gsc | goosecoid homeobox | 0.752 | |
| Lhx3 | LIM homeobox protein 3 | 0.746 | |
| Gpr50 | G-protein-coupled receptor 50 | 0.744 | |
| Efnb2 | ephrin B2 | 0.736 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.701 | |
| Rxra | retinoid X receptor alpha | 0.697 | |
| Rarg | retinoic acid receptor, gamma | 0.681 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.679 | |
| Onecut1 | one cut domain, family member 1 | 0.675 | |
| Vegfa | vascular endothelial growth factor A | 0.667 | |
| Insm1 | insulinoma-associated 1 | 0.645 | |
| Efna2 | ephrin A2 | 0.639 | |
| Meox2 | mesenchyme homeobox 2 | 0.636 | |
| Hoxd13 | homeobox D13 | 0.621 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.604 | |
| Nhlh1 | nescient helix loop helix 1 | 0.603 | |
| Mesp1 | mesoderm posterior 1 | 0.603 | |
| Sox2 | SRY-box containing gene 2 | 0.594 | |
| Tbx1 | T-box 1 | 0.587 | |
| Igdcc3 | immunoglobulin superfamily, DCC subclass, member 3 | 0.578 | |
| Dlx2 | distal-less homeobox 2 | 0.575 | |
| Epha4 | Eph receptor A4 | 0.570 | |
| Foxd2 | forkhead box D2 | 0.564 | |
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.554 | |
| Alx3 | aristaless-like homeobox 3 | 0.549 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.549 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.538 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.531 | |
| Nr5a1 | nuclear receptor subfamily 5, group A, member 1 | 0.523 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.519 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.517 | |
| Ebf3 | early B-cell factor 3 | 0.512 | |
| Neurog2 | neurogenin 2 | 0.507 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.504 | |
| Sox7 | SRY-box containing gene 7 | 0.494 | |
| Prrx2 | paired related homeobox 2 | 0.487 | |
| Dlx5 | distal-less homeobox 5 | 0.487 | |
| Atoh7 | atonal homolog 7 (Drosophila) | 0.484 | |
| Hoxa1 | homeobox A1 | 0.453 | |
| Mecom | MDS1 and EVI1 complex locus | 0.448 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.445 | |
| Lhx5 | LIM homeobox protein 5 | 0.443 | |
| Dlx1 | distal-less homeobox 1 | 0.436 | |
| Efnb1 | ephrin B1 | 0.435 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.418 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.417 | |
| Alx4 | aristaless-like homeobox 4 | 0.416 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.404 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.394 | |
| She | src homology 2 domain-containing transforming protein E | 0.386 | |
| Lhcgr | luteinizing hormone/choriogonadotropin receptor | 0.382 | |
| Sall3 | sal-like 3 (Drosophila) | 0.381 | |
| Tbx3 | T-box 3 | 0.379 | |
| Col2a1 | collagen, type II, alpha 1 | 0.374 | |
| Sox18 | SRY-box containing gene 18 | 0.358 | |
| Tcf15 | transcription factor 15 | 0.348 | |
| Cldn5 | claudin 5 | 0.344 | |
| Eng | endoglin | 0.334 | |
| Dll4 | delta-like 4 (Drosophila) | 0.322 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.321 | |
| Hoxa13 | homeobox A13 | 0.320 | |
| Six6 | sine oculis-related homeobox 6 homolog (Drosophila) | 0.318 | |
| Sox11 | SRY-box containing gene 11 | 0.315 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.315 | |
| Ece1 | endothelin converting enzyme 1 | 0.300 | |
| Hoxc4 | homeobox C4 | 0.298 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| JAG1 | jagged 1 | 1.000 | |
| TGFB1 | transforming growth factor, beta 1 | 0.996 | |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.995 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.993 | |
| FSTL1 | follistatin-like 1 | 0.967 | |
| TGFB3 | transforming growth factor, beta 3 | 0.950 | |
| BMP2 | bone morphogenetic protein 2 | 0.932 | |
| GDF5 | growth differentiation factor 5 | 0.888 | |
| SMAD7 | SMAD family member 7 | 0.856 | |
| ENG | endoglin | 0.837 | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.722 | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.702 | |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.674 | |
| NRP1 | neuropilin 1 | 0.660 | |
| DLL1 | delta-like 1 (Drosophila) | 0.646 | |
| ZMYND11 | zinc finger, MYND-type containing 11 | 0.638 | |
| NOTCH1 | notch 1 | 0.462 | |
| NOTCH2 | notch 2 | 0.393 | |
| XIAP | X-linked inhibitor of apoptosis | 0.334 | |
| JAG2 | jagged 2 | 0.320 | |
| PDGFC | platelet derived growth factor C | 0.275 | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.258 | |
| GSK3B | glycogen synthase kinase 3 beta | 0.202 | |
| SMAD2 | SMAD family member 2 | 0.193 | |
| MARCKSL1 | MARCKS-like 1 | 0.183 | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.173 | |
| RBBP4 | retinoblastoma binding protein 4 | 0.169 | |
| DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.163 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.143 | |
| RXRA | retinoid X receptor, alpha | 0.102 | |
| GFI1B | growth factor independent 1B transcription repressor | 0.100 | |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.096 | |
| NOTCH3 | notch 3 | 0.089 | |
| EGFL7 | EGF-like-domain, multiple 7 | 0.084 | |
| NOTCH2NL | notch 2 N-terminal like | 0.082 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.081 | |
| BMP4 | bone morphogenetic protein 4 | 0.076 | |
| NPR1 | natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) | 0.073 | |
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.071 | |
| CTBP2 | C-terminal binding protein 2 | 0.065 | |
| APP | amyloid beta (A4) precursor protein | 0.064 | |
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.061 | |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.056 | |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | 0.050 | |
| VEGFA | vascular endothelial growth factor A | 0.048 | |
| TGFBR3 | transforming growth factor, beta receptor III | 0.047 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.047 | |
| FNDC3B | fibronectin type III domain containing 3B | 0.045 | |
| ACVR1 | activin A receptor, type I | 0.044 | |
| ATXN1L | ataxin 1-like | 0.044 | |
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 0.042 | |
| ACVR1B | activin A receptor, type IB | 0.039 | |
| EFNB2 | ephrin-B2 | 0.038 | |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.037 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.032 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.031 | |
| KLK10 | kallikrein-related peptidase 10 | 0.031 | |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 | 0.030 | |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.030 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.030 | |
| ANTXR2 | anthrax toxin receptor 2 | 0.029 | |
| ICAM2 | intercellular adhesion molecule 2 | 0.029 | |
| HIC1 | hypermethylated in cancer 1 | 0.029 | |
| TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.028 | |
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.028 | |
| C20orf4 | chromosome 20 open reading frame 4 | 0.027 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.027 | |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.027 | |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.027 | |
| VWF | von Willebrand factor | 0.027 | |
| DOCK8 | dedicator of cytokinesis 8 | 0.026 | |
| GJB5 | gap junction protein, beta 5, 31.1kDa | 0.026 | |
| CD34 | CD34 molecule | 0.026 | |
| GATA2 | GATA binding protein 2 | 0.026 | |
| ACVRL1 | activin A receptor type II-like 1 | 0.026 | |
| MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.025 | |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.024 | |
| ACVR2A | activin A receptor, type IIA | 0.023 | |
| FOXF2 | forkhead box F2 | 0.022 | |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.022 | |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.022 | |
| AQP5 | aquaporin 5 | 0.021 | |
| NBPF10 | neuroblastoma breakpoint family, member 10 | 0.021 | |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.020 | |
| AXIN1 | axin 1 | 0.020 | |
| RBMS1 | RNA binding motif, single stranded interacting protein 1 | 0.020 | |
| TMEM44 | transmembrane protein 44 | 0.020 | |
| PCDH12 | protocadherin 12 | 0.019 | |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.019 | |
| MED25 | mediator complex subunit 25 | 0.019 | |
| CD248 | CD248 molecule, endosialin | 0.019 | |
| ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.018 | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.018 | |
| ACVR2B | activin A receptor, type IIB | 0.018 | |
| INHBB | inhibin, beta B | 0.018 | |
| GJB3 | gap junction protein, beta 3, 31kDa | 0.018 | |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.018 | |
| USP15 | ubiquitin specific peptidase 15 | 0.018 | |
| CLU | clusterin | 0.017 | |
| FZD7 | frizzled homolog 7 (Drosophila) | 0.017 |