The network for 'regulation of phospholipid catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of phospholipid catabolic process

Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.

Name Description Probability Func Analog Organism
Dab1 disabled homolog 1 (Drosophila) 0.993
Apoe apolipoprotein E 0.954
Cav1 caveolin 1, caveolae protein 0.918
Sqle squalene epoxidase 0.291
Scd1 stearoyl-Coenzyme A desaturase 1 0.283
Lrp1 low density lipoprotein receptor-related protein 1 0.209
Cyp51 cytochrome P450, family 51 0.181
Sc4mol sterol-C4-methyl oxidase-like 0.142
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 0.123
Il1r1 interleukin 1 receptor, type I 0.108
Lss lanosterol synthase 0.094
Reln reelin 0.089
Hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 0.087
Tnfrsf13b tumor necrosis factor receptor superfamily, member 13b 0.086
Pparg peroxisome proliferator activated receptor gamma 0.085
Ccl2 chemokine (C-C motif) ligand 2 0.083
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.083
Igh immunoglobulin heavy chain complex 0.077
Vldlr very low density lipoprotein receptor 0.062
Dhcr7 7-dehydrocholesterol reductase 0.062
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.061
Fbn1 fibrillin 1 0.057
Abca1 ATP-binding cassette, sub-family A (ABC1), member 1 0.054
Npc1 Niemann Pick type C1 0.052
Idi1 isopentenyl-diphosphate delta isomerase 0.049
Lrp8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor 0.047
Mvd mevalonate (diphospho) decarboxylase 0.047
Lpin1 lipin 1 0.046
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.046
Ghr growth hormone receptor 0.045
Crkl v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.041
Agtr1a angiotensin II receptor, type 1a 0.040
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.037
Ldlr low density lipoprotein receptor 0.035
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.031
Hsd17b7 hydroxysteroid (17-beta) dehydrogenase 7 0.029
Fabp4 fatty acid binding protein 4, adipocyte 0.029
Slc12a6 solute carrier family 12, member 6 0.028
Lpl lipoprotein lipase 0.027
Fas Fas (TNF receptor superfamily member 6) 0.026
Dhcr24 24-dehydrocholesterol reductase 0.026
Sc5d sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) 0.026
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.025
Cfh complement component factor h 0.025
Lcat lecithin cholesterol acyltransferase 0.024
Abhd5 abhydrolase domain containing 5 0.022
Soat1 sterol O-acyltransferase 1 0.022
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.022
Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 0.022
Tgfbr1 transforming growth factor, beta receptor I 0.021
Stard4 StAR-related lipid transfer (START) domain containing 4 0.021
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.020
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.020
Gjb2 gap junction protein, beta 2 0.020
Tgfbr2 transforming growth factor, beta receptor II 0.020
Lepr leptin receptor 0.018
Bcl6 B-cell leukemia/lymphoma 6 0.018
Btk Bruton agammaglobulinemia tyrosine kinase 0.016
Cd36 CD36 antigen 0.016
Tlr2 toll-like receptor 2 0.016
Cd40 CD40 antigen 0.016
Klf15 Kruppel-like factor 15 0.016
Gba glucosidase, beta, acid 0.015
Tlr4 toll-like receptor 4 0.015
Adamts1 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 1 0.015
Ncoa3 nuclear receptor coactivator 3 0.014
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) 0.014
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.014
Rora RAR-related orphan receptor alpha 0.013
Man2a1 mannosidase 2, alpha 1 0.012
Pygl liver glycogen phosphorylase 0.012
Bpnt1 bisphosphate 3'-nucleotidase 1 0.012
Flt1 FMS-like tyrosine kinase 1 0.012
Srebf2 sterol regulatory element binding factor 2 0.011
Pdk4 pyruvate dehydrogenase kinase, isoenzyme 4 0.011
Timp3 tissue inhibitor of metalloproteinase 3 0.011
Aacs acetoacetyl-CoA synthetase 0.011
Stat3 signal transducer and activator of transcription 3 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.584
NUMB numb homolog (Drosophila) 0.053
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.051
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.048
APOE apolipoprotein E 0.040
NOXA1 NADPH oxidase activator 1 0.029
MAPT microtubule-associated protein tau 0.026
ZNF71 zinc finger protein 71 0.026
CCDC115 coiled-coil domain containing 115 0.023
PDPK1 3-phosphoinositide dependent protein kinase-1 0.019
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.017
PRKCZ protein kinase C, zeta 0.017
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.017
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.015
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.015
CDC37 cell division cycle 37 homolog (S. cerevisiae) 0.014
APOA1 apolipoprotein A-I 0.014
DCTN1 dynactin 1 0.013
HP haptoglobin 0.013
CYBA cytochrome b-245, alpha polypeptide 0.013
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.013
NCF1 neutrophil cytosolic factor 1 0.012
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.012
VHL von Hippel-Lindau tumor suppressor 0.012
CDCP1 CUB domain containing protein 1 0.010
TRIM9 tripartite motif containing 9 0.010
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.010
ALB albumin 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism