The network for 'atrial ventricular junction remodeling' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

atrial ventricular junction remodeling

The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle.

Danio rerio
Name Description Probability Func Analog Organism
tbx5a T-box 5a 0.999
shha sonic hedgehog a 0.966
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.966
bmp4 bone morphogenetic protein 4 0.936
cdh2 cadherin 2, neuronal 0.886
hand2 heart and neural crest derivatives expressed transcript 2 0.869
tbx2a T-box gene 2a 0.809
nkx2.5 NK2 transcription factor related 5 0.771
ntla no tail a 0.771
flh floating head 0.761
prdm1a PR domain containing 1a, with ZNF domain 0.747
tbx1 T-box 1 0.723
hnf1ba HNF1 homeobox Ba 0.709
fgf8a fibroblast growth factor 8 a 0.654
runx1 runt-related transcription factor 1 0.641
bmp2b bone morphogenetic protein 2b 0.610
ptch1 patched 1 0.565
notch1a notch homolog 1a 0.494
tbx24 T-box 24 0.443
mib mind bomb 0.431
myf5 myogenic factor 5 0.420
her1 hairy-related 1 0.417
myl7 myosin, light polypeptide 7, regulatory 0.415
fgf10a fibroblast growth factor 10a 0.375
tnnc1a troponin C type 1a (slow) 0.347
has2 hyaluronan synthase 2 0.328
fn1 fibronectin 1 0.315
tll1 tolloid-like 1 0.311
myod1 myogenic differentiation 1 0.304
wnt11 wingless-type MMTV integration site family, member 11 0.287
tbx18 T-box 18 0.269
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.266
oep one-eyed pinhead 0.258
her7 hairy and enhancer of split related-7 0.257
pkd2 polycystic kidney disease 2 0.245
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.244
mitfa microphthalmia-associated transcription factor a 0.243
ndr2 nodal-related 2 0.233
tbx20 T-box 20 0.233
lft1 lefty1 0.215
chd chordin 0.214
lft2 lefty2 0.204
lhx2b LIM homeobox 2b 0.201
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.194
tbx16 T-box gene 16 0.190
mef2cb myocyte enhancer factor 2cb 0.190
drl draculin 0.178
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.170
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.160
cdx4 caudal type homeo box transcription factor 4 0.156
wnt9a wingless-type MMTV integration site family, member 9A 0.154
tal1 T-cell acute lymphocytic leukemia 1 0.152
hoxd10a homeo box D10a 0.147
msxc muscle segment homeobox C 0.145
tbx2b T-box 2b 0.136
prrx1b paired related homeobox 1b 0.131
lef1 lymphocyte enhancer binding factor 1 0.129
hoxd11a homeo box D11a 0.129
osr2 odd-skipped related 2 (Drosophila) 0.128
tgfb3 transforming growth factor, beta 3 0.124
tbx5b T-box 5b 0.116
smo smoothened homolog (Drosophila) 0.110
dcc deleted in colorectal carcinoma 0.106
isl1 islet1 0.106
satb2 SATB homeobox 2 0.106
msgn1 mesogenin 1 0.106
hoxd13a homeo box D13a 0.101
dld deltaD 0.100
pcdh8 protocadherin 8 0.095
wnt5b wingless-type MMTV integration site family, member 5b 0.092
dlx2a distal-less homeobox gene 2a 0.092
slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.091
scube2 signal peptide, CUB domain, EGF-like 2 0.090
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.090
lmo4a LIM domain only 4a 0.087
eomesa eomesodermin homolog a 0.084
crip2 cysteine-rich protein 2 0.084
trim33 tripartite motif-containing 33 0.080
smyd1b SET and MYND domain containing 1b 0.078
nfatc1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.077
pax6a paired box gene 6a 0.077
tcf21 transcription factor 21 0.077
vent ventral expressed homeobox 0.076
foxh1 forkhead box H1 0.072
otx2 orthodenticle homolog 2 0.072
lrrc6 leucine rich repeat containing 6 0.070
gata6 GATA-binding protein 6 0.067
sulf1 sulfatase 1 0.066
tgfb2 transforming growth factor, beta 2 0.065
rx3 retinal homeobox gene 3 0.064
cdh5 cadherin 5 0.064
aplnrb apelin receptor b 0.064
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.062
hoxa13a homeo box A13a 0.061
vmhc ventricular myosin heavy chain 0.060
gbx2 gastrulation brain homeo box 2 0.059
hoxa13b homeo box A13b 0.056
cxcr4a chemokine (C-X-C motif) receptor 4a 0.055
limk1 LIM domain kinase 1 0.054
hspb12 heat shock protein, alpha-crystallin-related, b12 0.054
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 1.000
Scn5a sodium channel, voltage-gated, type V, alpha 1.000
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.999
Tbx3 T-box 3 0.999
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.994
Tgfb2 transforming growth factor, beta 2 0.991
Hand2 heart and neural crest derivatives expressed transcript 2 0.985
Fgfr2 fibroblast growth factor receptor 2 0.977
Ryr2 ryanodine receptor 2, cardiac 0.974
Pitx2 paired-like homeodomain transcription factor 2 0.971
Shh sonic hedgehog 0.946
Foxc1 forkhead box C1 0.938
Fgf8 fibroblast growth factor 8 0.936
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.922
Foxc2 forkhead box C2 0.914
Bmp4 bone morphogenetic protein 4 0.890
Ighmbp2 immunoglobulin mu binding protein 2 0.835
Hand1 heart and neural crest derivatives expressed transcript 1 0.823
Msx2 homeobox, msh-like 2 0.769
Pax3 paired box gene 3 0.715
Jag1 jagged 1 0.698
Nos3 nitric oxide synthase 3, endothelial cell 0.667
Gata4 GATA binding protein 4 0.657
Tcfap2a transcription factor AP-2, alpha 0.647
Zfpm2 zinc finger protein, multitype 2 0.616
Egfr epidermal growth factor receptor 0.602
Runx2 runt related transcription factor 2 0.586
Vegfa vascular endothelial growth factor A 0.535
Tbx1 T-box 1 0.528
Sox9 SRY-box containing gene 9 0.500
Tbx5 T-box 5 0.474
Pthlh parathyroid hormone-like peptide 0.470
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.465
Pcdh12 protocadherin 12 0.464
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.461
Rxra retinoid X receptor alpha 0.429
Tjp1 tight junction protein 1 0.428
Gjb6 gap junction protein, beta 6 0.412
Ntf3 neurotrophin 3 0.412
Gja1 gap junction protein, alpha 1 0.351
Gjb4 gap junction protein, beta 4 0.311
Fut2 fucosyltransferase 2 0.280
Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 0.274
Msx1 homeobox, msh-like 1 0.255
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.255
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.225
Col13a1 collagen, type XIII, alpha 1 0.224
Dsc1 desmocollin 1 0.211
Gjb2 gap junction protein, beta 2 0.209
Gata6 GATA binding protein 6 0.208
Irx3 Iroquois related homeobox 3 (Drosophila) 0.201
Sall4 sal-like 4 (Drosophila) 0.199
Mesp1 mesoderm posterior 1 0.193
Tgfbr2 transforming growth factor, beta receptor II 0.186
Ltbp1 latent transforming growth factor beta binding protein 1 0.183
Lmna lamin A 0.179
Pax6 paired box gene 6 0.177
Klk6 kallikrein related-peptidase 6 0.170
Tcfap2c transcription factor AP-2, gamma 0.166
Rhox6 reproductive homeobox 6 0.164
Adra1b adrenergic receptor, alpha 1b 0.157
Krt34 keratin 34 0.156
Bmp2 bone morphogenetic protein 2 0.152
Ern2 endoplasmic reticulum (ER) to nucleus signalling 2 0.148
Gli2 GLI-Kruppel family member GLI2 0.148
Pitx1 paired-like homeodomain transcription factor 1 0.147
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.140
Clic3 chloride intracellular channel 3 0.138
F12 coagulation factor XII (Hageman factor) 0.133
Meox2 mesenchyme homeobox 2 0.129
Slurp1 secreted Ly6/Plaur domain containing 1 0.124
Prrx1 paired related homeobox 1 0.118
Slc16a8 solute carrier family 16 (monocarboxylic acid transporters), member 8 0.115
Krt35 keratin 35 0.114
Kel Kell blood group 0.114
Slc26a4 solute carrier family 26, member 4 0.105
Atoh7 atonal homolog 7 (Drosophila) 0.103
Npas1 neuronal PAS domain protein 1 0.102
Gli3 GLI-Kruppel family member GLI3 0.102
Tcf15 transcription factor 15 0.101
Oprd1 opioid receptor, delta 1 0.101
Mt4 metallothionein 4 0.100
Gsc goosecoid homeobox 0.099
Dot1l DOT1-like, histone H3 methyltransferase (S. cerevisiae) 0.098
Alx1 ALX homeobox 1 0.095
Fgf10 fibroblast growth factor 10 0.094
Gpc3 glypican 3 0.094
Fgf3 fibroblast growth factor 3 0.093
Adam17 a disintegrin and metallopeptidase domain 17 0.093
Prph2 peripherin 2 0.092
Alx4 aristaless-like homeobox 4 0.091
Scn10a sodium channel, voltage-gated, type X, alpha 0.090
Fut1 fucosyltransferase 1 0.087
Foxh1 forkhead box H1 0.084
Hspb7 heat shock protein family, member 7 (cardiovascular) 0.083
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.082
Alx3 aristaless-like homeobox 3 0.082
Dlx5 distal-less homeobox 5 0.081
U46068 cDNA sequence U46068 0.080
Kcne1l potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene 0.080
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism