The network for 'endodermal digestive tract morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

endodermal digestive tract morphogenesis

The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.

Danio rerio
Name Description Probability Func Analog Organism
ndr2 nodal-related 2 0.797
lamb1a laminin, beta 1a 0.779
fgf8a fibroblast growth factor 8 a 0.772
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.649
shha sonic hedgehog a 0.608
tp53 tumor protein p53 0.504
cdh2 cadherin 2, neuronal 0.458
mib mind bomb 0.437
sox2 SRY-box containing gene 2 0.434
sox32 SRY-box containing gene 32 0.405
sox11a SRY-box containing gene 11a 0.402
fn1 fibronectin 1 0.369
hnf1ba HNF1 homeobox Ba 0.356
tbx1 T-box 1 0.349
ptch2 patched 2 0.340
gli1 GLI-Kruppel family member 1 0.321
chd chordin 0.317
dharma dharma 0.282
mpp5a membrane protein, palmitoylated 5a (MAGUK p55 subfamily member 5a) 0.274
gli2a GLI-Kruppel family member GLI2a 0.257
oep one-eyed pinhead 0.253
ptch1 patched 1 0.226
hhip hedgehog interacting protein 0.216
gdf6a growth differentiation factor 6a 0.201
lft1 lefty1 0.187
cxcr4a chemokine (C-X-C motif) receptor 4a 0.182
gata5 GATA-binding protein 5 0.158
dld deltaD 0.154
wls wntless homolog (Drosophila) 0.151
dag1 dystroglycan 1 0.146
fbn2b fibrillin 2b 0.138
nr2f1a nuclear receptor subfamily 2, group F, member 1a 0.135
pax6a paired box gene 6a 0.127
wnt11 wingless-type MMTV integration site family, member 11 0.127
cdx4 caudal type homeo box transcription factor 4 0.119
bon bonnie and clyde 0.118
cxcl12a chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) 0.108
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.104
wnt5b wingless-type MMTV integration site family, member 5b 0.102
smo smoothened homolog (Drosophila) 0.101
col11a2 collagen type XI alpha-2 0.098
sox17 SRY-box containing gene 17 0.098
prkci protein kinase C, iota 0.098
pou5f1 POU domain, class 5, transcription factor 1 0.098
gsc goosecoid 0.098
fgf3 fibroblast growth factor 3 0.097
cdc25 cell division cycle 25 homolog 0.095
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.094
flh floating head 0.087
hspa5 heat shock protein 5 0.087
bmp7a bone morphogenetic protein 7a 0.086
foxa3 forkhead box A3 0.084
nog1 noggin 1 0.083
smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.081
pax2a paired box gene 2a 0.077
ext2 exostoses (multiple) 2 0.075
meis1 myeloid ecotropic viral integration 1 0.071
vangl2 vang-like 2 (van gogh, Drosophila) 0.069
wif1 wnt inhibitory factor 1 0.067
mmp2 matrix metalloproteinase 2 0.064
tll1 tolloid-like 1 0.062
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.061
wnt8b wingless-type MMTV integration site family, member 8b 0.057
nkx2.2a NK2 transcription factor related 2a 0.057
sox4a SRY-box containing gene 4a 0.056
spns2 spinster homolog 2 (Drosophila) 0.056
met met proto-oncogene (hepatocyte growth factor receptor) 0.052
dnajb11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.052
snai1b snail homolog 1b (Drosophila) 0.050
sema3aa semaphorin 3aa 0.049
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.049
tbx16 T-box gene 16 0.049
dlc deltaC 0.045
pax3a paired box gene 3a 0.043
dkk1b dickkopf 1b 0.043
admp anti-dorsalizing morphogenic protein 0.043
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.043
dbx1a developing brain homeobox 1a 0.043
col8a1a collagen, type VIII, alpha 1a 0.042
sox4b SRY-box containing gene 4b 0.042
ndr1 nodal-related 1 0.042
sec61al1 Sec61 alpha like 1 0.041
rarab retinoic acid receptor, alpha b 0.041
cxcr4b chemokine (C-X-C motif), receptor 4b 0.041
pitx3 paired-like homeodomain transcription factor 3 0.040
axin1 axin 1 0.040
lfng lunatic fringe homolog 0.040
manf mesencephalic astrocyte-derived neurotrophic factor 0.039
gpc4 glypican 4 0.039
disp1 dispatched homolog 1 (Drosophila) 0.038
fgfr2 fibroblast growth factor receptor 2 0.038
vent ventral expressed homeobox 0.037
wnt4a wingless-type MMTV integration site family, member 4a 0.037
pdip5 protein disulfide isomerase-related protein (provisional) 0.037
hgfa hepatocyte growth factor a 0.036
neurod neurogenic differentiation 0.036
lama1 laminin, alpha 1 0.036
pth2 parathyroid hormone 2 0.035
zgc:63523 zgc:63523 0.035
sox9b SRY-box containing gene 9b 0.035
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
stumps CG31317 gene product from transcript CG31317-RC 0.086
LanA Laminin A 0.021
nrv2 nervana 2 0.020
srp serpent 0.018
htl heartless 0.015
LanB1 CG7123 gene product from transcript CG7123-RA 0.014
noc no ocelli 0.011
bnl branchless 0.010
fng fringe 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 0.996
Gli3 GLI-Kruppel family member GLI3 0.975
Shh sonic hedgehog 0.974
Sox9 SRY-box containing gene 9 0.961
Id3 inhibitor of DNA binding 3 0.954
Ctnnb1 catenin (cadherin associated protein), beta 1 0.898
Fgfr3 fibroblast growth factor receptor 3 0.895
Pax3 paired box gene 3 0.846
Bmp4 bone morphogenetic protein 4 0.788
Id1 inhibitor of DNA binding 1 0.743
Tcfap2a transcription factor AP-2, alpha 0.737
She src homology 2 domain-containing transforming protein E 0.479
Fgfr1 fibroblast growth factor receptor 1 0.447
Tcf4 transcription factor 4 0.398
Tbx3 T-box 3 0.382
Hes1 hairy and enhancer of split 1 (Drosophila) 0.379
Hspa5 heat shock protein 5 0.335
Isl1 ISL1 transcription factor, LIM/homeodomain 0.328
Meox2 mesenchyme homeobox 2 0.297
Sox2 SRY-box containing gene 2 0.290
Pitx1 paired-like homeodomain transcription factor 1 0.266
Vangl2 vang-like 2 (van gogh, Drosophila) 0.261
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.247
Efnb2 ephrin B2 0.245
Rara retinoic acid receptor, alpha 0.223
Tbx4 T-box 4 0.220
Fgf10 fibroblast growth factor 10 0.203
Lamb1 laminin B1 0.196
Pitx2 paired-like homeodomain transcription factor 2 0.178
Gli2 GLI-Kruppel family member GLI2 0.176
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.172
Trp63 transformation related protein 63 0.172
Nog noggin 0.169
Foxc1 forkhead box C1 0.165
Sox11 SRY-box containing gene 11 0.156
Pax2 paired box gene 2 0.153
Ret ret proto-oncogene 0.152
Smad6 MAD homolog 6 (Drosophila) 0.149
Dll4 delta-like 4 (Drosophila) 0.144
Emx2 empty spiracles homolog 2 (Drosophila) 0.137
Smpd3 sphingomyelin phosphodiesterase 3, neutral 0.126
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.118
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.115
Hoxa5 homeobox A5 0.106
Tbx2 T-box 2 0.106
Otx2 orthodenticle homolog 2 (Drosophila) 0.098
Pkd1 polycystic kidney disease 1 homolog 0.098
Ptprb protein tyrosine phosphatase, receptor type, B 0.096
Jag1 jagged 1 0.095
Sox4 SRY-box containing gene 4 0.095
Pax6 paired box gene 6 0.089
Lhx3 LIM homeobox protein 3 0.088
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.086
Chd7 chromodomain helicase DNA binding protein 7 0.086
Col2a1 collagen, type II, alpha 1 0.082
Rarb retinoic acid receptor, beta 0.081
Tcf3 transcription factor 3 0.081
Pax1 paired box gene 1 0.080
Rarg retinoic acid receptor, gamma 0.080
Cldn5 claudin 5 0.078
Meox1 mesenchyme homeobox 1 0.073
Rxra retinoid X receptor alpha 0.072
Hand1 heart and neural crest derivatives expressed transcript 1 0.071
Sox17 SRY-box containing gene 17 0.069
Fgf8 fibroblast growth factor 8 0.068
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.065
Sox18 SRY-box containing gene 18 0.062
Egfr epidermal growth factor receptor 0.059
Pthlh parathyroid hormone-like peptide 0.057
Ihh Indian hedgehog 0.057
Otx1 orthodenticle homolog 1 (Drosophila) 0.056
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.054
Bmp5 bone morphogenetic protein 5 0.053
Nphp4 nephronophthisis 4 (juvenile) homolog (human) 0.052
Gata3 GATA binding protein 3 0.052
Zeb1 zinc finger E-box binding homeobox 1 0.049
Alx4 aristaless-like homeobox 4 0.049
Gata4 GATA binding protein 4 0.048
Ddah2 dimethylarginine dimethylaminohydrolase 2 0.047
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.045
Hoxa13 homeobox A13 0.044
Hey1 hairy/enhancer-of-split related with YRPW motif 1 0.044
Pdia3 protein disulfide isomerase associated 3 0.043
Hes5 hairy and enhancer of split 5 (Drosophila) 0.043
Nf1 neurofibromatosis 1 0.043
Edar ectodysplasin-A receptor 0.042
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.042
Prrx1 paired related homeobox 1 0.042
Hoxa3 homeobox A3 0.041
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.040
Wnt9b wingless-type MMTV integration site 9B 0.039
Canx calnexin 0.038
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.038
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.037
Clic3 chloride intracellular channel 3 0.037
Lama5 laminin, alpha 5 0.036
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.036
Olig2 oligodendrocyte transcription factor 2 0.035
Tcf7l1 transcription factor 7-like 1 (T-cell specific, HMG box) 0.035
Wnt5a wingless-related MMTV integration site 5A 0.035
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism