The network for 'ventricular cardiac muscle tissue morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ventricular cardiac muscle tissue morphogenesis

The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.

Danio rerio
Name Description Probability Func Analog Organism
tbx1 T-box 1 0.999
myod1 myogenic differentiation 1 0.977
ttna titin a 0.937
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.929
smyhc2 slow myosin heavy chain 2 0.908
tbx5a T-box 5a 0.880
tnnt3b troponin T3b, skeletal, fast 0.879
tnnc1b troponin C type 1b (slow) 0.872
actn3b actinin alpha 3b 0.867
nkx2.5 NK2 transcription factor related 5 0.847
tal1 T-cell acute lymphocytic leukemia 1 0.844
gata2a GATA-binding protein 2a 0.805
tnni1al troponin I, skeletal, slow like 0.794
tnni1b troponin I, skeletal, slow b 0.754
smyhc1 slow myosin heavy chain 1 0.753
smyd1b SET and MYND domain containing 1b 0.746
smyhc1l slow myosin heavy chain 1, like 0.728
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.719
ryr3 ryanodine receptor 3 0.718
alcamb activated leukocyte cell adhesion molecule b 0.716
myl7 myosin, light polypeptide 7, regulatory 0.646
tnni2a.4 troponin I, skeletal, fast 2a.4 0.641
tbx20 T-box 20 0.633
hspb1 heat shock protein, alpha-crystallin-related, 1 0.630
fn1 fibronectin 1 0.607
alcama activated leukocyte cell adhesion molecule a 0.583
cmlc1 cardiac myosin light chain-1 0.576
gata5 GATA-binding protein 5 0.555
bmp4 bone morphogenetic protein 4 0.548
rbm24a RNA binding motif protein 24a 0.530
dlc deltaC 0.527
vmhc ventricular myosin heavy chain 0.516
wnt11r wingless-type MMTV integration site family, member 11, related 0.477
slc8a1a solute carrier family 8 (sodium/calcium exchanger), member 1a 0.475
unc45b unc-45 homolog B (C. elegans) 0.464
aplnrb apelin receptor b 0.455
mef2cb myocyte enhancer factor 2cb 0.453
foxc1a forkhead box C1a 0.451
myog myogenin 0.448
cdh2 cadherin 2, neuronal 0.421
notch3 notch homolog 3 0.398
mylz2 myosin, light polypeptide 2, skeletal muscle 0.395
hand2 heart and neural crest derivatives expressed transcript 2 0.391
hhex hematopoietically expressed homeobox 0.378
six1b sine oculis homeobox homolog 1b 0.375
tnnt2a troponin T2a, cardiac 0.360
col11a1b collagen type XI alpha-1b and collagen, type XI, alpha 1b 0.343
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.326
actc1b actin, alpha, cardiac muscle 1b 0.326
tnnc2 troponin C type 2 (fast) 0.322
ckma creatine kinase, muscle a 0.316
rnasel1 ribonuclease like 1 0.312
mef2ca myocyte enhancer factor 2ca 0.285
etv2 ets variant gene 2 0.281
wu:fv91b12 wu:fv91b12 0.277
dll4 delta-like 4 (Drosophila) 0.259
tpma alpha-tropomyosin 0.255
atp2a2a ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a 0.244
actc1a actin, alpha, cardiac muscle 1a 0.241
tnnt3a troponin T3a, skeletal, fast 0.226
ptprja protein tyrosine phosphatase, receptor type, J a 0.222
hnf1ba HNF1 homeobox Ba 0.221
rbfox1l RNA binding protein, fox-1 homolog (C. elegans) 1-like 0.215
chrna1 cholinergic receptor, nicotinic, alpha polypeptide 1 0.198
myl1 myosin, light chain 1, alkali; skeletal, fast 0.197
ogg1 8-oxoguanine DNA glycosylase 0.190
shha sonic hedgehog a 0.188
tmem88a transmembrane protein 88 a 0.188
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.180
oep one-eyed pinhead 0.180
tfap2a transcription factor AP-2 alpha 0.175
hsp90a.1 heat shock protein 90-alpha 1 0.170
fgf8a fibroblast growth factor 8 a 0.161
nfatc1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 0.159
apobec2a apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2a 0.143
pitx2 paired-like homeodomain transcription factor 2 0.137
zgc:66286 zgc:66286 0.136
actn2 actinin, alpha 2 0.132
sox2 SRY-box containing gene 2 0.130
hspa12b heat shock protein 12B 0.128
spaw southpaw 0.124
bmper BMP binding endothelial regulator 0.122
ccm2 cerebral cavernous malformation 2 0.115
bmp2b bone morphogenetic protein 2b 0.114
tnnt1 troponin T1, skeletal, slow 0.114
tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.112
tbx2b T-box 2b 0.111
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.111
xirp2a xin actin-binding repeat containing 2a 0.108
isl1 islet1 0.108
lft2 lefty2 0.107
foxi1 forkhead box I1 0.107
cdx4 caudal type homeo box transcription factor 4 0.107
dld deltaD 0.106
myhz1.1 myosin, heavy polypeptide 1.1, skeletal muscle 0.106
acta1a actin, alpha 1a, skeletal muscle 0.104
tp63 tumor protein p63 0.103
slc25a37 solute carrier family 25, member 37 0.100
fhla four and a half LIM domains a 0.099
atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.099
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
TNNC1 troponin C type 1 (slow) 0.998
TNNI1 troponin I type 1 (skeletal, slow) 0.993
MYH9 myosin, heavy chain 9, non-muscle 0.982
TPM1 tropomyosin 1 (alpha) 0.803
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.716
TNNI2 troponin I type 2 (skeletal, fast) 0.710
TRIM63 tripartite motif containing 63 0.693
TPM2 tropomyosin 2 (beta) 0.651
ACTA1 actin, alpha 1, skeletal muscle 0.645
DSP desmoplakin 0.595
SMYD1 SET and MYND domain containing 1 0.531
TNNT3 troponin T type 3 (skeletal, fast) 0.500
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 0.476
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.428
TNNT2 troponin T type 2 (cardiac) 0.412
TBX5 T-box 5 0.392
CKM creatine kinase, muscle 0.373
ZYX zyxin 0.350
MYOD1 myogenic differentiation 1 0.338
MYL1 myosin, light chain 1, alkali; skeletal, fast 0.309
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.307
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.287
ACTN2 actinin, alpha 2 0.230
SETD8 SET domain containing (lysine methyltransferase) 8 0.226
JUP junction plakoglobin 0.205
LDB3 LIM domain binding 3 0.201
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.181
JAG1 jagged 1 0.176
KRT14 keratin 14 0.169
CXXC5 CXXC finger protein 5 0.161
PSEN1 presenilin 1 0.159
MYH1 myosin, heavy chain 1, skeletal muscle, adult 0.142
ACVR1B activin A receptor, type IB 0.137
PDLIM7 PDZ and LIM domain 7 (enigma) 0.135
TNNT1 troponin T type 1 (skeletal, slow) 0.135
NOTCH1 notch 1 0.131
MYH7 myosin, heavy chain 7, cardiac muscle, beta 0.130
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.123
MYLPF myosin light chain, phosphorylatable, fast skeletal muscle 0.122
FGF10 fibroblast growth factor 10 0.120
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.119
HAP1 huntingtin-associated protein 1 0.111
MYL2 myosin, light chain 2, regulatory, cardiac, slow 0.107
MYBPC2 myosin binding protein C, fast type 0.100
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.082
DES desmin 0.082
HNF4A hepatocyte nuclear factor 4, alpha 0.077
SMAD3 SMAD family member 3 0.069
MYOZ1 myozenin 1 0.066
MYH2 myosin, heavy chain 2, skeletal muscle, adult 0.065
TAL1 T-cell acute lymphocytic leukemia 1 0.061
NOTCH3 notch 3 0.060
TNNC2 troponin C type 2 (fast) 0.057
PKP2 plakophilin 2 0.057
ACTC1 actin, alpha, cardiac muscle 1 0.056
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 0.054
GATA2 GATA binding protein 2 0.053
GSK3B glycogen synthase kinase 3 beta 0.051
GATA1 GATA binding protein 1 (globin transcription factor 1) 0.049
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.047
TCAP titin-cap (telethonin) 0.047
ACTN3 actinin, alpha 3 0.046
TGFBR1 transforming growth factor, beta receptor 1 0.044
MYBPC1 myosin binding protein C, slow type 0.040
FRMD5 FERM domain containing 5 0.039
MYL3 myosin, light chain 3, alkali; ventricular, skeletal, slow 0.039
TTN titin 0.038
SMAD2 SMAD family member 2 0.037
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.037
PAX8 paired box 8 0.037
CTBP2 C-terminal binding protein 2 0.037
SGCA sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein) 0.036
KRT18 keratin 18 0.035
MYOG myogenin (myogenic factor 4) 0.035
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle) 0.035
PTPRJ protein tyrosine phosphatase, receptor type, J 0.035
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.034
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.032
FLNA filamin A, alpha 0.031
MARK3 MAP/microtubule affinity-regulating kinase 3 0.031
MYBPH myosin binding protein H 0.030
PKP4 plakophilin 4 0.030
SMAD9 SMAD family member 9 0.029
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) 0.028
PDX1 pancreatic and duodenal homeobox 1 0.026
AKAP6 A kinase (PRKA) anchor protein 6 0.025
CASQ2 calsequestrin 2 (cardiac muscle) 0.023
ACTB actin, beta 0.023
MYL12B myosin, light chain 12B, regulatory 0.023
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.022
ESR2 estrogen receptor 2 (ER beta) 0.022
SMAD6 SMAD family member 6 0.021
SMPX small muscle protein, X-linked 0.021
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 0.021
ACTN1 actinin, alpha 1 0.020
TGFB1 transforming growth factor, beta 1 0.019
MAML1 mastermind-like 1 (Drosophila) 0.018
TAGLN transgelin 0.018
CNN1 calponin 1, basic, smooth muscle 0.018
CORO1C coronin, actin binding protein, 1C 0.018
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Mus musculus
Name Description Probability Func Analog Organism
Hand2 heart and neural crest derivatives expressed transcript 2 1.000
Pitx2 paired-like homeodomain transcription factor 2 0.998
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.993
Gata4 GATA binding protein 4 0.990
Shh sonic hedgehog 0.989
Foxc1 forkhead box C1 0.987
Tbx1 T-box 1 0.985
Otx2 orthodenticle homolog 2 (Drosophila) 0.978
Isl1 ISL1 transcription factor, LIM/homeodomain 0.976
Notch1 Notch gene homolog 1 (Drosophila) 0.974
Fgf8 fibroblast growth factor 8 0.968
Pax2 paired box gene 2 0.962
Gli3 GLI-Kruppel family member GLI3 0.961
Lhx3 LIM homeobox protein 3 0.936
Hand1 heart and neural crest derivatives expressed transcript 1 0.910
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.901
Foxa2 forkhead box A2 0.869
Fgfr2 fibroblast growth factor receptor 2 0.834
Foxc2 forkhead box C2 0.825
Hoxd13 homeobox D13 0.804
Nog noggin 0.800
Lhx1 LIM homeobox protein 1 0.779
Pdx1 pancreatic and duodenal homeobox 1 0.727
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.688
Meox2 mesenchyme homeobox 2 0.685
Sox9 SRY-box containing gene 9 0.663
Bmp4 bone morphogenetic protein 4 0.632
Mesp1 mesoderm posterior 1 0.627
Pax3 paired box gene 3 0.626
Hoxa13 homeobox A13 0.614
Gata6 GATA binding protein 6 0.614
Rxra retinoid X receptor alpha 0.613
Tlx3 T-cell leukemia, homeobox 3 0.599
Pthlh parathyroid hormone-like peptide 0.590
Foxh1 forkhead box H1 0.570
Gsc goosecoid homeobox 0.554
Dlx2 distal-less homeobox 2 0.553
Jag1 jagged 1 0.545
En1 engrailed 1 0.527
Pax9 paired box gene 9 0.523
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.521
Msx1 homeobox, msh-like 1 0.517
Fgfr1 fibroblast growth factor receptor 1 0.514
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.485
Eya1 eyes absent 1 homolog (Drosophila) 0.482
Scn5a sodium channel, voltage-gated, type V, alpha 0.472
She src homology 2 domain-containing transforming protein E 0.466
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.466
Tbx3 T-box 3 0.465
Insm1 insulinoma-associated 1 0.462
Dlx5 distal-less homeobox 5 0.455
Klk1b11 kallikrein 1-related peptidase b11 0.448
Klk1 kallikrein 1 0.434
Neurog2 neurogenin 2 0.430
Pitx1 paired-like homeodomain transcription factor 1 0.419
Klk1b26 kallikrein 1-related petidase b26 0.393
Sox2 SRY-box containing gene 2 0.388
Col1a1 collagen, type I, alpha 1 0.378
Nodal nodal 0.362
Hoxd11 homeobox D11 0.357
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.349
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.348
Gli2 GLI-Kruppel family member GLI2 0.344
Myog myogenin 0.340
Tgfb2 transforming growth factor, beta 2 0.337
Ctnnb1 catenin (cadherin associated protein), beta 1 0.332
Neurod4 neurogenic differentiation 4 0.328
Hoxd3 homeobox D3 0.327
Foxf1a forkhead box F1a 0.319
Rarg retinoic acid receptor, gamma 0.318
Col4a1 collagen, type IV, alpha 1 0.312
Dll4 delta-like 4 (Drosophila) 0.310
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.307
Wnt7a wingless-related MMTV integration site 7A 0.305
Dcc deleted in colorectal carcinoma 0.303
Pitx3 paired-like homeodomain transcription factor 3 0.303
Pax6 paired box gene 6 0.298
Col5a1 collagen, type V, alpha 1 0.295
Emx1 empty spiracles homolog 1 (Drosophila) 0.292
Pax8 paired box gene 8 0.290
Psen1 presenilin 1 0.284
Fgfr3 fibroblast growth factor receptor 3 0.282
Foxg1 forkhead box G1 0.278
Ptf1a pancreas specific transcription factor, 1a 0.272
Msx2 homeobox, msh-like 2 0.271
Col3a1 collagen, type III, alpha 1 0.269
Pax1 paired box gene 1 0.268
Col2a1 collagen, type II, alpha 1 0.266
Neurog1 neurogenin 1 0.265
Emx2 empty spiracles homolog 2 (Drosophila) 0.253
Tal2 T-cell acute lymphocytic leukemia 2 0.252
Col1a2 collagen, type I, alpha 2 0.246
Sox3 SRY-box containing gene 3 0.245
Sox7 SRY-box containing gene 7 0.241
Hoxa1 homeobox A1 0.241
Six2 sine oculis-related homeobox 2 homolog (Drosophila) 0.237
Klk1b21 kallikrein 1-related peptidase b21 0.235
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.235
Ntf3 neurotrophin 3 0.234
Ldb3 LIM domain binding 3 0.231
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism