IMP

Process View

Homo sapiens

4 genes annotated in human

regulation of b cell receptor signaling pathway

Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in human Include functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of b cell receptor signaling pathway"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of b cell receptor signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.561
PTK2	PTK2 protein tyrosine kinase 2	0.543
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.520
FHL2	four and a half LIM domains 2	0.491
TFF1	trefoil factor 1	0.398
NCF1	neutrophil cytosolic factor 1	0.315
NCK2	NCK adaptor protein 2	0.254
LPXN	leupaxin	0.227
SYK	spleen tyrosine kinase	0.200
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.182
BCAR1	breast cancer anti-estrogen resistance 1	0.145
LIMS1	LIM and senescent cell antigen-like domains 1	0.143	Human
CD22	CD22 molecule	0.135
GRB2	growth factor receptor-bound protein 2	0.102
VCL	vinculin	0.100
CD247	CD247 molecule	0.085
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.078
CD33	CD33 molecule	0.070
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.069
PILRA	paired immunoglobin-like type 2 receptor alpha	0.068
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.067
PECAM1	platelet/endothelial cell adhesion molecule	0.063
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.062
CYBA	cytochrome b-245, alpha polypeptide	0.060
HOXA1	homeobox A1	0.059
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.059
SH2D2A	SH2 domain containing 2A	0.057
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.056
VAV1	vav 1 guanine nucleotide exchange factor	0.051
TRIP6	thyroid hormone receptor interactor 6	0.050
PRKCD	protein kinase C, delta	0.047
LCK	lymphocyte-specific protein tyrosine kinase	0.047
MEST	mesoderm specific transcript homolog (mouse)	0.046
PHC2	polyhomeotic homolog 2 (Drosophila)	0.044
LAT	linker for activation of T cells	0.043
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.043
RICTOR	RPTOR independent companion of MTOR, complex 2	0.042
PRKCQ	protein kinase C, theta	0.040
BBS10	Bardet-Biedl syndrome 10	0.039
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.038
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.035
HDAC6	histone deacetylase 6	0.035
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.034
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.033
EPOR	erythropoietin receptor	0.029
ZNF426	zinc finger protein 426	0.029
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.029
TRIM9	tripartite motif containing 9	0.028
ADRBK1	adrenergic, beta, receptor kinase 1	0.027
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.023
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.023
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.022
SH2D1A	SH2 domain containing 1A	0.022
PHF21A	PHD finger protein 21A	0.022
ILK	integrin-linked kinase	0.021
SIGLEC10	sialic acid binding Ig-like lectin 10	0.020
DPEP2	dipeptidase 2	0.020
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.020
LRMP	lymphoid-restricted membrane protein	0.020
SH3BP2	SH3-domain binding protein 2	0.019
IL4R	interleukin 4 receptor	0.019
RABAC1	Rab acceptor 1 (prenylated)	0.018
CTTN	cortactin	0.017
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.016
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.016
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.016
AHNAK	AHNAK nucleoprotein	0.015
CD300LF	CD300 molecule-like family member f	0.015	Human
ZNF331	zinc finger protein 331	0.015
NCF4	neutrophil cytosolic factor 4, 40kDa	0.014
AIF1	allograft inflammatory factor 1	0.014
WDYHV1	WDYHV motif containing 1	0.014
HIPK3	homeodomain interacting protein kinase 3	0.014
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.014
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.013
DLG1	discs, large homolog 1 (Drosophila)	0.013
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.013
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.013
GAB1	GRB2-associated binding protein 1	0.013
CD2	CD2 molecule	0.012
FAM65B	family with sequence similarity 65, member B	0.012
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.012
KIR2DL1	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	0.012
RALBP1	ralA binding protein 1	0.012
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.012
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.012
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.011
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.011
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.011
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.011	Human
ARHGAP9	Rho GTPase activating protein 9	0.011
ITGA7	integrin, alpha 7	0.011
CD72	CD72 molecule	0.011
PRKCA	protein kinase C, alpha	0.011	Human
SIRPA	signal-regulatory protein alpha	0.011
TLN1	talin 1	0.011
RNF5	ring finger protein 5	0.010
FHOD1	formin homology 2 domain containing 1	0.010
ADAMTSL4	ADAMTS-like 4	0.010
SKAP1	src kinase associated phosphoprotein 1	0.010
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.010
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.010
CD37	CD37 molecule	0.010