IMP

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Homo sapiens

17 genes annotated in human

regulation of calcium mediated signaling

Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of calcium mediated signaling"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of calcium mediated signaling" (in gray)

Name	Description	Probability	Func Analog Organism
LCK	lymphocyte-specific protein tyrosine kinase	0.999
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.920	Mouse
LAT	linker for activation of T cells	0.739
CCR5	chemokine (C-C motif) receptor 5	0.726
VAV1	vav 1 guanine nucleotide exchange factor	0.719
CD247	CD247 molecule	0.596
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.588
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.510
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.385
CD3D	CD3d molecule, delta (CD3-TCR complex)	0.271
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.257
CCL4	chemokine (C-C motif) ligand 4	0.254
CD28	CD28 molecule	0.232
FYN	FYN oncogene related to SRC, FGR, YES	0.191
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.182	Human
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.170
DPP4	dipeptidyl-peptidase 4	0.150
CCL8	chemokine (C-C motif) ligand 8	0.147	Human
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.121
FYB	FYN binding protein	0.118
CTNND1	catenin (cadherin-associated protein), delta 1	0.114
PSEN2	presenilin 2 (Alzheimer disease 4)	0.109
PLCG1	phospholipase C, gamma 1	0.106
CCL13	chemokine (C-C motif) ligand 13	0.103	Human
SYK	spleen tyrosine kinase	0.101	Mouse
PTPRC	protein tyrosine phosphatase, receptor type, C	0.100
ITK	IL2-inducible T-cell kinase	0.095
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.090
CCL2	chemokine (C-C motif) ligand 2	0.088	Human
CXCL9	chemokine (C-X-C motif) ligand 9	0.085
TRPC4	transient receptor potential cation channel, subfamily C, member 4	0.083
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.079	Human
AXIN1	axin 1	0.078
CCR7	chemokine (C-C motif) receptor 7	0.074
DSG2	desmoglein 2	0.074
CCR1	chemokine (C-C motif) receptor 1	0.073
CD163	CD163 molecule	0.069
SH3BP2	SH3-domain binding protein 2	0.064
IGF2R	insulin-like growth factor 2 receptor	0.061
ITGB1BP3	integrin beta 1 binding protein 3	0.060
CCL19	chemokine (C-C motif) ligand 19	0.058	Human
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.055	Mouse
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.053
PLK3	polo-like kinase 3	0.052
MATK	megakaryocyte-associated tyrosine kinase	0.045
SLAMF8	SLAM family member 8	0.044
IDE	insulin-degrading enzyme	0.041
CCL3	chemokine (C-C motif) ligand 3	0.039
JUP	junction plakoglobin	0.038
C1QA	complement component 1, q subcomponent, A chain	0.038
IL7R	interleukin 7 receptor	0.037
CD2	CD2 molecule	0.035
CCL22	chemokine (C-C motif) ligand 22	0.034	Human
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.031
FHL1	four and a half LIM domains 1	0.030
IL10	interleukin 10	0.030
IL6	interleukin 6 (interferon, beta 2)	0.029
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.029
IL2RB	interleukin 2 receptor, beta	0.029
SASH3	SAM and SH3 domain containing 3	0.029
IL1B	interleukin 1, beta	0.029
CCL7	chemokine (C-C motif) ligand 7	0.028	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.028
CXCL3	chemokine (C-X-C motif) ligand 3	0.027
AQP9	aquaporin 9	0.027
SH2D1A	SH2 domain containing 1A	0.026
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.026
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.025
CXCL10	chemokine (C-X-C motif) ligand 10	0.025
DSP	desmoplakin	0.024
PSEN1	presenilin 1	0.024
CSF1R	colony stimulating factor 1 receptor	0.023
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.023
CXCL13	chemokine (C-X-C motif) ligand 13	0.023
CCL5	chemokine (C-C motif) ligand 5	0.023	Human
FPR3	formyl peptide receptor 3	0.022	Human
IL1RN	interleukin 1 receptor antagonist	0.022
HCK	hemopoietic cell kinase	0.021
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.021
IL8	interleukin 8	0.021
TREM1	triggering receptor expressed on myeloid cells 1	0.021
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.021
CXCL5	chemokine (C-X-C motif) ligand 5	0.020
RGS1	regulator of G-protein signaling 1	0.019
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.019
C3AR1	complement component 3a receptor 1	0.018	Human
CYBB	cytochrome b-245, beta polypeptide	0.018
CST7	cystatin F (leukocystatin)	0.018
HMG20A	high mobility group 20A	0.018
DARC	Duffy blood group, chemokine receptor	0.017
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.017
IL2RG	interleukin 2 receptor, gamma	0.017
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.017
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.017
CCR4	chemokine (C-C motif) receptor 4	0.017
PLEK	pleckstrin	0.017
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.017	Human
ADORA3	adenosine A3 receptor	0.016
IFNG	interferon, gamma	0.016
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.016
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.016
IL18RAP	interleukin 18 receptor accessory protein	0.016
IL21R	interleukin 21 receptor	0.016
CDK17	cyclin-dependent kinase 17	0.015
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.015
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.015
C2	complement component 2	0.015
TNF	tumor necrosis factor	0.015
VSIG4	V-set and immunoglobulin domain containing 4	0.015
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.015
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.014
CXCL2	chemokine (C-X-C motif) ligand 2	0.014
NKG7	natural killer cell group 7 sequence	0.014
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.014
IL10RA	interleukin 10 receptor, alpha	0.014
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.014
FPR1	formyl peptide receptor 1	0.014	Human
FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	0.014
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.014
SLA	Src-like-adaptor	0.014	Human
SH2D2A	SH2 domain containing 2A	0.013
EGFR	epidermal growth factor receptor	0.013
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.013
PRKCQ	protein kinase C, theta	0.013
C1QB	complement component 1, q subcomponent, B chain	0.013
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.013
CXCL11	chemokine (C-X-C motif) ligand 11	0.013
SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.013
ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	0.013
DLG2	discs, large homolog 2 (Drosophila)	0.013
CD80	CD80 molecule	0.012
GZMK	granzyme K (granzyme 3; tryptase II)	0.012
GNLY	granulysin	0.012
GRB2	growth factor receptor-bound protein 2	0.012	Human
STAT4	signal transducer and activator of transcription 4	0.012
MARCO	macrophage receptor with collagenous structure	0.012
CD52	CD52 molecule	0.012
CTTN	cortactin	0.012
ADAMDEC1	ADAM-like, decysin 1	0.012
C5AR1	complement component 5a receptor 1	0.012	Human
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.012
MS4A4A	membrane-spanning 4-domains, subfamily A, member 4	0.012
MS4A6A	membrane-spanning 4-domains, subfamily A, member 6A	0.011
ITGAM	integrin, alpha M (complement component 3 receptor 3 subunit)	0.011
CLEC5A	C-type lectin domain family 5, member A	0.011
CCR3	chemokine (C-C motif) receptor 3	0.011
CD4	CD4 molecule	0.011	Mouse
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.011
SNX9	sorting nexin 9	0.010
CD83	CD83 molecule	0.010
SELE	selectin E	0.010
ITGB7	integrin, beta 7	0.010
UBASH3B	ubiquitin associated and SH3 domain containing B	0.010
WASL	Wiskott-Aldrich syndrome-like	0.010
MSR1	macrophage scavenger receptor 1	0.010
IL1R2	interleukin 1 receptor, type II	0.010