IMP

Process View

Homo sapiens

20 genes annotated in human

endoplasmic reticulum organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "endoplasmic reticulum organization"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "endoplasmic reticulum organization" (in gray)

Name	Description	Probability	Func Analog Organism
TOR1A	torsin family 1, member A (torsin A)	1.000	Human
PDE6D	phosphodiesterase 6D, cGMP-specific, rod, delta	0.992
RTN4	reticulon 4	0.991
SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.956
COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.917	Mouse
FBXW11	F-box and WD repeat domain containing 11	0.910
CANX	calnexin	0.906
SEC31A	SEC31 homolog A (S. cerevisiae)	0.811	Zebrafish
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.809
ATP13A2	ATPase type 13A2	0.801
PEX12	peroxisomal biogenesis factor 12	0.746
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.713
CAV1	caveolin 1, caveolae protein, 22kDa	0.667
SEC13	SEC13 homolog (S. cerevisiae)	0.550	Zebrafish
TOR1AIP2	torsin A interacting protein 2	0.549
TACC3	transforming, acidic coiled-coil containing protein 3	0.473
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.467
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.431
TOR1B	torsin family 1, member B (torsin B)	0.420
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.407
CALU	calumenin	0.386
RPN1	ribophorin I	0.362
SEC23A	Sec23 homolog A (S. cerevisiae)	0.351
APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.348
ARF4	ADP-ribosylation factor 4	0.347
SEPT7	septin 7	0.278
SSR1	signal sequence receptor, alpha	0.278
SEPT6	septin 6	0.239
RABIF	RAB interacting factor	0.227
DAZAP2	DAZ associated protein 2	0.141
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.121
FAM160A2	family with sequence similarity 160, member A2	0.115
RAB3GAP1	RAB3 GTPase activating protein subunit 1 (catalytic)	0.108
ARL3	ADP-ribosylation factor-like 3	0.096
PDIA6	protein disulfide isomerase family A, member 6	0.091
TACC1	transforming, acidic coiled-coil containing protein 1	0.088
GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)	0.084
SURF4	surfeit 4	0.083
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.082
RTN3	reticulon 3	0.081
CNIH4	cornichon homolog 4 (Drosophila)	0.073
SEC61B	Sec61 beta subunit	0.073
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.072
GOLM1	golgi membrane protein 1	0.066
NPTN	neuroplastin	0.065
VCP	valosin containing protein	0.064
SAV1	salvador homolog 1 (Drosophila)	0.062
ARCN1	archain 1	0.061
TMED9	transmembrane emp24 protein transport domain containing 9	0.060
ECH1	enoyl CoA hydratase 1, peroxisomal	0.059
SEPT11	septin 11	0.058
SLC35B1	solute carrier family 35, member B1	0.056
TUBA1C	tubulin, alpha 1c	0.055
TMED2	transmembrane emp24 domain trafficking protein 2	0.054
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.052
UBXN4	UBX domain protein 4	0.046
RAB14	RAB14, member RAS oncogene family	0.046
PTPRF	protein tyrosine phosphatase, receptor type, F	0.045
DAD1	defender against cell death 1	0.043
DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.043
GFPT1	glutamine--fructose-6-phosphate transaminase 1	0.042
TUBA1B	tubulin, alpha 1b	0.041
NINL	ninein-like	0.041
ZDHHC5	zinc finger, DHHC-type containing 5	0.040
PFDN1	prefoldin subunit 1	0.040
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.040
DCTN4	dynactin 4 (p62)	0.038
YTHDF3	YTH domain family, member 3	0.037
UBL4A	ubiquitin-like 4A	0.037
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.037
TRAM1	translocation associated membrane protein 1	0.036
ACBD3	acyl-CoA binding domain containing 3	0.036
WRAP73	WD repeat containing, antisense to TP73	0.036
GOLGA4	golgin A4	0.036
SPOP	speckle-type POZ protein	0.035
GORASP2	golgi reassembly stacking protein 2, 55kDa	0.035
PRR13	proline rich 13	0.035
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.034
SNCAIP	synuclein, alpha interacting protein	0.034
TOR1AIP1	torsin A interacting protein 1	0.033	Human
TMEM208	transmembrane protein 208	0.033
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.033
GNA13	guanine nucleotide binding protein (G protein), alpha 13	0.032
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.032
TDGF1	teratocarcinoma-derived growth factor 1	0.031
RAB27A	RAB27A, member RAS oncogene family	0.030
NAT15	N-acetyltransferase 15 (GCN5-related, putative)	0.029
RHEB	Ras homolog enriched in brain	0.029
COG5	component of oligomeric golgi complex 5	0.028
SEC24C	SEC24 family, member C (S. cerevisiae)	0.027
USP3	ubiquitin specific peptidase 3	0.027
GAK	cyclin G associated kinase	0.027	Mouse
F2R	coagulation factor II (thrombin) receptor	0.027
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.027
NUCB2	nucleobindin 2	0.026
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.026
DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10	0.026
TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)	0.024
MADD	MAP-kinase activating death domain	0.024
OPTN	optineurin	0.024
TTR	transthyretin	0.023
YIPF6	Yip1 domain family, member 6	0.022
STX5	syntaxin 5	0.022
SRPRB	signal recognition particle receptor, B subunit	0.022
FEZ2	fasciculation and elongation protein zeta 2 (zygin II)	0.022
DEGS1	degenerative spermatocyte homolog 1, lipid desaturase (Drosophila)	0.022
CUL1	cullin 1	0.021
CSNK1G2	casein kinase 1, gamma 2	0.021
SSR3	signal sequence receptor, gamma (translocon-associated protein gamma)	0.021
RPN2	ribophorin II	0.021	Worm
AP1S1	adaptor-related protein complex 1, sigma 1 subunit	0.021
MAGED1	melanoma antigen family D, 1	0.020
SEC16A	SEC16 homolog A (S. cerevisiae)	0.020
TNNT1	troponin T type 1 (skeletal, slow)	0.020
SELS	selenoprotein S	0.020
UGCG	UDP-glucose ceramide glucosyltransferase	0.020
CANT1	calcium activated nucleotidase 1	0.019
COPG	coatomer protein complex, subunit gamma	0.019
RAB3GAP2	RAB3 GTPase activating protein subunit 2 (non-catalytic)	0.019
BCAP31	B-cell receptor-associated protein 31	0.019
SRPR	signal recognition particle receptor (docking protein)	0.019
GARS	glycyl-tRNA synthetase	0.019
NFYA	nuclear transcription factor Y, alpha	0.018
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.018
TWSG1	twisted gastrulation homolog 1 (Drosophila)	0.017
SNAPIN	SNAP-associated protein	0.017
CSK	c-src tyrosine kinase	0.017
ARL2	ADP-ribosylation factor-like 2	0.016
OSBP	oxysterol binding protein	0.016
GCC2	GRIP and coiled-coil domain containing 2	0.016
GOLGA3	golgin A3	0.016
CHIC2	cysteine-rich hydrophobic domain 2	0.016
SNUPN	snurportin 1	0.016
LMAN1	lectin, mannose-binding, 1	0.016
UBAC2	UBA domain containing 2	0.015
ARPC1A	actin related protein 2/3 complex, subunit 1A, 41kDa	0.015
USO1	USO1 vesicle docking protein homolog (yeast)	0.015
RAB33A	RAB33A, member RAS oncogene family	0.015
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.015
EPRS	glutamyl-prolyl-tRNA synthetase	0.015
MGRN1	mahogunin, ring finger 1	0.014
TMEM50B	transmembrane protein 50B	0.014
LRPAP1	low density lipoprotein receptor-related protein associated protein 1	0.014
SEC24D	SEC24 family, member D (S. cerevisiae)	0.014
EXT2	exostosin 2	0.014
PMM2	phosphomannomutase 2	0.014
UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1	0.014
NOMO3	NODAL modulator 3	0.014
SECISBP2L	SECIS binding protein 2-like	0.014
PDIA3	protein disulfide isomerase family A, member 3	0.013
HIP1	huntingtin interacting protein 1	0.013
BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	0.013
ATXN2	ataxin 2	0.013
IRF3	interferon regulatory factor 3	0.013
CLIC4	chloride intracellular channel 4	0.013
RPS6KC1	ribosomal protein S6 kinase, 52kDa, polypeptide 1	0.012
FAM193A	family with sequence similarity 193, member A	0.012
AAK1	AP2 associated kinase 1	0.012
IMMT	inner membrane protein, mitochondrial	0.012
PTMS	parathymosin	0.012
KAT5	K(lysine) acetyltransferase 5	0.012
UBE2J2	ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)	0.012
NCK2	NCK adaptor protein 2	0.012
NOMO1	NODAL modulator 1	0.012
FAM32A	family with sequence similarity 32, member A	0.012
C9orf25	chromosome 9 open reading frame 25	0.012
GOLGA5	golgin A5	0.012
TNIP2	TNFAIP3 interacting protein 2	0.012
TXNRD1	thioredoxin reductase 1	0.012
RAB13	RAB13, member RAS oncogene family	0.011	Human Yeast
SYT11	synaptotagmin XI	0.011	Yeast
UBE2L3	ubiquitin-conjugating enzyme E2L 3	0.011
C7orf42	chromosome 7 open reading frame 42	0.011
UBL7	ubiquitin-like 7 (bone marrow stromal cell-derived)	0.011
ARHGEF18	Rho/Rac guanine nucleotide exchange factor (GEF) 18	0.011
POU2F1	POU class 2 homeobox 1	0.011
CHPF2	chondroitin polymerizing factor 2	0.011
MED8	mediator complex subunit 8	0.011
C12orf23	chromosome 12 open reading frame 23	0.011
DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2	0.011
FAS	Fas (TNF receptor superfamily, member 6)	0.011
ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.011
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.011
FYTTD1	forty-two-three domain containing 1	0.011
WDR47	WD repeat domain 47	0.011
VPS37A	vacuolar protein sorting 37 homolog A (S. cerevisiae)	0.010
RAB8A	RAB8A, member RAS oncogene family	0.010	Human Yeast
ASNA1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	0.010
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.010
CNOT1	CCR4-NOT transcription complex, subunit 1	0.010
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.010
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.010
STON2	stonin 2	0.010
CLIP1	CAP-GLY domain containing linker protein 1	0.010
FEM1C	fem-1 homolog c (C. elegans)	0.010