IMP

Process View

Homo sapiens

22 genes annotated in human

nitric oxide metabolic process

The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nitric oxide metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "nitric oxide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.990	Human
EGFR	epidermal growth factor receptor	0.987
TICAM2	toll-like receptor adaptor molecule 2	0.682
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.570
IL1R1	interleukin 1 receptor, type I	0.528
INSR	insulin receptor	0.523
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.484
ESR1	estrogen receptor 1	0.419
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.412
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.313
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.301
NOSTRIN	nitric oxide synthase trafficker	0.296
DERL1	Der1-like domain family, member 1	0.210
IRAK2	interleukin-1 receptor-associated kinase 2	0.198
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.181	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.148
IL10RA	interleukin 10 receptor, alpha	0.112
TNIP2	TNFAIP3 interacting protein 2	0.105
LAT	linker for activation of T cells	0.102
PRKCZ	protein kinase C, zeta	0.099	Human
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.095
BCAR1	breast cancer anti-estrogen resistance 1	0.095
KLF4	Kruppel-like factor 4 (gut)	0.092
NOXA1	NADPH oxidase activator 1	0.088
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.086
CAV1	caveolin 1, caveolae protein, 22kDa	0.072	Mouse
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.071	Fly
IGF1R	insulin-like growth factor 1 receptor	0.066	Human
VAC14	Vac14 homolog (S. cerevisiae)	0.060
DLG2	discs, large homolog 2 (Drosophila)	0.045
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.041
KLF6	Kruppel-like factor 6	0.040	Human
STAT5A	signal transducer and activator of transcription 5A	0.039
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.038	Human
SOCS3	suppressor of cytokine signaling 3	0.038
IL8	interleukin 8	0.038
IRS1	insulin receptor substrate 1	0.037
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.037
ALDOB	aldolase B, fructose-bisphosphate	0.035
DLG4	discs, large homolog 4 (Drosophila)	0.035
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.035
PPP5C	protein phosphatase 5, catalytic subunit	0.033
DUSP1	dual specificity phosphatase 1	0.032
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.032
MPDZ	multiple PDZ domain protein	0.031
MYLK2	myosin light chain kinase 2	0.030
EHMT2	euchromatic histone-lysine N-methyltransferase 2	0.030
SSTR2	somatostatin receptor 2	0.029	Human
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.028
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.028
TRPC1	transient receptor potential cation channel, subfamily C, member 1	0.028
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.027
CDCP1	CUB domain containing protein 1	0.026
DDR2	discoidin domain receptor tyrosine kinase 2	0.025
FYN	FYN oncogene related to SRC, FGR, YES	0.025
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.024
APP	amyloid beta (A4) precursor protein	0.024
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.024
IL1RAP	interleukin 1 receptor accessory protein	0.024
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.023
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.022
IL1R2	interleukin 1 receptor, type II	0.021
MYD88	myeloid differentiation primary response gene (88)	0.021
ZC3H12A	zinc finger CCCH-type containing 12A	0.020
CCL14	chemokine (C-C motif) ligand 14	0.020
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.019
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.019
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.019
FOSL2	FOS-like antigen 2	0.019
JUN	jun proto-oncogene	0.018
PECAM1	platelet/endothelial cell adhesion molecule	0.017
MAP2K4	mitogen-activated protein kinase kinase 4	0.017
CALCA	calcitonin-related polypeptide alpha	0.017
GHR	growth hormone receptor	0.016
XPO7	exportin 7	0.016
MAPT	microtubule-associated protein tau	0.016
SH2D1A	SH2 domain containing 1A	0.016
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.015
SYK	spleen tyrosine kinase	0.015
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.015
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.015
MATK	megakaryocyte-associated tyrosine kinase	0.015
SH3RF1	SH3 domain containing ring finger 1	0.015
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.015
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.015
PPARG	peroxisome proliferator-activated receptor gamma	0.014
SSTR3	somatostatin receptor 3	0.014	Human
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.014
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.013
PRKCD	protein kinase C, delta	0.013	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.013
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.013
PGRMC1	progesterone receptor membrane component 1	0.013
NUMB	numb homolog (Drosophila)	0.013
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.013
SQSTM1	sequestosome 1	0.012
NCF4	neutrophil cytosolic factor 4, 40kDa	0.012
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.012
PLAUR	plasminogen activator, urokinase receptor	0.012
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.012
TRADD	TNFRSF1A-associated via death domain	0.012
JAK2	Janus kinase 2	0.012	Rat
EGR2	early growth response 2	0.012
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.012
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.012
GAB2	GRB2-associated binding protein 2	0.012
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.012
EMP1	epithelial membrane protein 1	0.011
HCST	hematopoietic cell signal transducer	0.011
VAV3	vav 3 guanine nucleotide exchange factor	0.011
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.011	Fly
BCL3	B-cell CLL/lymphoma 3	0.011
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.011
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.011
NCF1	neutrophil cytosolic factor 1	0.010
GAB1	GRB2-associated binding protein 1	0.010
RNF19B	ring finger protein 19B	0.010
CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1	0.010
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.010