IMP

Process View

Homo sapiens

4 genes annotated in human

cellular response to macrophage colony stimulating factor stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to macrophage colony stimulating factor stimulus"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cellular response to macrophage colony stimulating factor stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
VEGFA	vascular endothelial growth factor A	0.956
PLCG1	phospholipase C, gamma 1	0.819
GHR	growth hormone receptor	0.807
PTPRB	protein tyrosine phosphatase, receptor type, B	0.776
NRP1	neuropilin 1	0.768
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.704
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.687
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.576	Human
PDGFA	platelet-derived growth factor alpha polypeptide	0.567
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.524	Human
PGF	placental growth factor	0.495
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.487	Human
CDH5	cadherin 5, type 2 (vascular endothelium)	0.422
SOS1	son of sevenless homolog 1 (Drosophila)	0.291
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.236
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.223
ZNF746	zinc finger protein 746	0.211
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.205
GAB1	GRB2-associated binding protein 1	0.183
PHYHIPL	phytanoyl-CoA 2-hydroxylase interacting protein-like	0.176
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.146	Human
FYN	FYN oncogene related to SRC, FGR, YES	0.131
PDGFC	platelet derived growth factor C	0.126
FYB	FYN binding protein	0.086
INSR	insulin receptor	0.073
SLA	Src-like-adaptor	0.066
FASLG	Fas ligand (TNF superfamily, member 6)	0.065
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.057
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.056
KITLG	KIT ligand	0.053
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.049
ITGA1	integrin, alpha 1	0.047
GRB7	growth factor receptor-bound protein 7	0.043
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.043
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.039
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.038
GRAP2	GRB2-related adaptor protein 2	0.037
CAV1	caveolin 1, caveolae protein, 22kDa	0.036
BCAR1	breast cancer anti-estrogen resistance 1	0.034
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.032
LAT	linker for activation of T cells	0.030
ZNF775	zinc finger protein 775	0.030
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.029
SH2D1A	SH2 domain containing 1A	0.028
LDLR	low density lipoprotein receptor	0.027
TGFB3	transforming growth factor, beta 3	0.027
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.024
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.023
FGFR1	fibroblast growth factor receptor 1	0.023
FLT4	fms-related tyrosine kinase 4	0.021	Human
TRIM32	tripartite motif containing 32	0.021
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.020
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.018
PRKCQ	protein kinase C, theta	0.018
VAV1	vav 1 guanine nucleotide exchange factor	0.018
IRS1	insulin receptor substrate 1	0.018
PTEN	phosphatase and tensin homolog	0.018
PDE4DIP	phosphodiesterase 4D interacting protein	0.017
MAPK8	mitogen-activated protein kinase 8	0.016
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.016
SOCS1	suppressor of cytokine signaling 1	0.016
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.016
CD2	CD2 molecule	0.016
NSF	N-ethylmaleimide-sensitive factor	0.016
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.015
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.015
HSPG2	heparan sulfate proteoglycan 2	0.015
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.015
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.015
STAT5A	signal transducer and activator of transcription 5A	0.014
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.014
EZR	ezrin	0.014
SYK	spleen tyrosine kinase	0.013
GAB2	GRB2-associated binding protein 2	0.013
CMIP	c-Maf-inducing protein	0.013
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.013	Human
GRB10	growth factor receptor-bound protein 10	0.013
FNBP1	formin binding protein 1	0.013
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.013
GPR171	G protein-coupled receptor 171	0.012
FAS	Fas (TNF receptor superfamily, member 6)	0.012
CD34	CD34 molecule	0.012
PIM1	pim-1 oncogene	0.012
RAMP3	receptor (G protein-coupled) activity modifying protein 3	0.012
MAP2	microtubule-associated protein 2	0.012
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.012
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.011
EGFR	epidermal growth factor receptor	0.011
TEK	TEK tyrosine kinase, endothelial	0.011
EPHB1	EPH receptor B1	0.011
CLDN5	claudin 5	0.011
VEGFC	vascular endothelial growth factor C	0.010
JAK2	Janus kinase 2	0.010
CD93	CD93 molecule	0.010
PDE7B	phosphodiesterase 7B	0.010	Human
PCDH12	protocadherin 12	0.010
SOCS2	suppressor of cytokine signaling 2	0.010
ENPEP	glutamyl aminopeptidase (aminopeptidase A)	0.010
FIGF	c-fos induced growth factor (vascular endothelial growth factor D)	0.010