Process View
The network for 'cellular response to macrophage colony stimulating factor stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| VEGFA | vascular endothelial growth factor A | 0.956 | |
| PLCG1 | phospholipase C, gamma 1 | 0.819 | |
| GHR | growth hormone receptor | 0.807 | |
| PTPRB | protein tyrosine phosphatase, receptor type, B | 0.776 | |
| NRP1 | neuropilin 1 | 0.768 | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.704 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.687 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.576 | |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.567 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.524 | |
| PGF | placental growth factor | 0.495 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.487 | |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.422 | |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.291 | |
| SHC2 | SHC (Src homology 2 domain containing) transforming protein 2 | 0.236 | |
| PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.223 | |
| ZNF746 | zinc finger protein 746 | 0.211 | |
| LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.205 | |
| GAB1 | GRB2-associated binding protein 1 | 0.183 | |
| PHYHIPL | phytanoyl-CoA 2-hydroxylase interacting protein-like | 0.176 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.146 | |
| FYN | FYN oncogene related to SRC, FGR, YES | 0.131 | |
| PDGFC | platelet derived growth factor C | 0.126 | |
| FYB | FYN binding protein | 0.086 | |
| INSR | insulin receptor | 0.073 | |
| SLA | Src-like-adaptor | 0.066 | |
| FASLG | Fas ligand (TNF superfamily, member 6) | 0.065 | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.057 | |
| CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.056 | |
| KITLG | KIT ligand | 0.053 | |
| CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.049 | |
| ITGA1 | integrin, alpha 1 | 0.047 | |
| GRB7 | growth factor receptor-bound protein 7 | 0.043 | |
| PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.043 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.039 | |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.038 | |
| GRAP2 | GRB2-related adaptor protein 2 | 0.037 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.036 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.034 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.032 | |
| LAT | linker for activation of T cells | 0.030 | |
| ZNF775 | zinc finger protein 775 | 0.030 | |
| WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.029 | |
| SH2D1A | SH2 domain containing 1A | 0.028 | |
| LDLR | low density lipoprotein receptor | 0.027 | |
| TGFB3 | transforming growth factor, beta 3 | 0.027 | |
| ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.024 | |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.023 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.023 | |
| FLT4 | fms-related tyrosine kinase 4 | 0.021 | |
| TRIM32 | tripartite motif containing 32 | 0.021 | |
| PTPN3 | protein tyrosine phosphatase, non-receptor type 3 | 0.020 | |
| PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.018 | |
| PRKCQ | protein kinase C, theta | 0.018 | |
| VAV1 | vav 1 guanine nucleotide exchange factor | 0.018 | |
| IRS1 | insulin receptor substrate 1 | 0.018 | |
| PTEN | phosphatase and tensin homolog | 0.018 | |
| PDE4DIP | phosphodiesterase 4D interacting protein | 0.017 | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.016 | |
| PIK3CB | phosphoinositide-3-kinase, catalytic, beta polypeptide | 0.016 | |
| SOCS1 | suppressor of cytokine signaling 1 | 0.016 | |
| PIK3CD | phosphoinositide-3-kinase, catalytic, delta polypeptide | 0.016 | |
| CD2 | CD2 molecule | 0.016 | |
| NSF | N-ethylmaleimide-sensitive factor | 0.016 | |
| ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.015 | |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.015 | |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.015 | |
| ROBO4 | roundabout homolog 4, magic roundabout (Drosophila) | 0.015 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.015 | |
| STAT5A | signal transducer and activator of transcription 5A | 0.014 | |
| RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.014 | |
| EZR | ezrin | 0.014 | |
| SYK | spleen tyrosine kinase | 0.013 | |
| GAB2 | GRB2-associated binding protein 2 | 0.013 | |
| CMIP | c-Maf-inducing protein | 0.013 | |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.013 | |
| GRB10 | growth factor receptor-bound protein 10 | 0.013 | |
| FNBP1 | formin binding protein 1 | 0.013 | |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 | 0.013 | |
| GPR171 | G protein-coupled receptor 171 | 0.012 | |
| FAS | Fas (TNF receptor superfamily, member 6) | 0.012 | |
| CD34 | CD34 molecule | 0.012 | |
| PIM1 | pim-1 oncogene | 0.012 | |
| RAMP3 | receptor (G protein-coupled) activity modifying protein 3 | 0.012 | |
| MAP2 | microtubule-associated protein 2 | 0.012 | |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.012 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.011 | |
| EGFR | epidermal growth factor receptor | 0.011 | |
| TEK | TEK tyrosine kinase, endothelial | 0.011 | |
| EPHB1 | EPH receptor B1 | 0.011 | |
| CLDN5 | claudin 5 | 0.011 | |
| VEGFC | vascular endothelial growth factor C | 0.010 | |
| JAK2 | Janus kinase 2 | 0.010 | |
| CD93 | CD93 molecule | 0.010 | |
| PDE7B | phosphodiesterase 7B | 0.010 | |
| PCDH12 | protocadherin 12 | 0.010 | |
| SOCS2 | suppressor of cytokine signaling 2 | 0.010 | |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) | 0.010 | |
| FIGF | c-fos induced growth factor (vascular endothelial growth factor D) | 0.010 |
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Vegfa | vascular endothelial growth factor A | 0.862 | |
| Kdr | kinase insert domain protein receptor | 0.562 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.332 | |
| Tgfb1 | transforming growth factor, beta 1 | 0.170 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.165 | |
| Runx2 | runt related transcription factor 2 | 0.139 | |
| Ptprb | protein tyrosine phosphatase, receptor type, B | 0.130 | |
| Kitl | kit ligand | 0.127 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.124 | |
| Lepr | leptin receptor | 0.101 | |
| Ldlr | low density lipoprotein receptor | 0.088 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.084 | |
| Cdh5 | cadherin 5 | 0.081 | |
| Ednrb | endothelin receptor type B | 0.080 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.079 | |
| Vegfc | vascular endothelial growth factor C | 0.073 | |
| Il6st | interleukin 6 signal transducer | 0.071 | |
| Tie1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.064 | |
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.061 | |
| Cbl | Casitas B-lineage lymphoma | 0.061 | |
| Flt4 | FMS-like tyrosine kinase 4 | 0.060 | |
| Col1a1 | collagen, type I, alpha 1 | 0.059 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.057 | |
| Efnb2 | ephrin B2 | 0.055 | |
| Slc9a3r2 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 | 0.053 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.049 | |
| Apc | adenomatosis polyposis coli | 0.040 | |
| Lyz2 | lysozyme 2 | 0.040 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.039 | |
| Fyn | Fyn proto-oncogene | 0.037 | |
| Tiparp | TCDD-inducible poly(ADP-ribose) polymerase | 0.037 | |
| Acvr1 | activin A receptor, type 1 | 0.036 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.034 | |
| Trp53 | transformation related protein 53 | 0.034 | |
| Mitf | microphthalmia-associated transcription factor | 0.030 | |
| Kit | kit oncogene | 0.029 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.028 | |
| Tmem204 | transmembrane protein 204 | 0.028 | |
| Col4a2 | collagen, type IV, alpha 2 | 0.027 | |
| Bmp2 | bone morphogenetic protein 2 | 0.026 | |
| Gucy1b3 | guanylate cyclase 1, soluble, beta 3 | 0.026 | |
| Ptch1 | patched homolog 1 | 0.026 | |
| Gja1 | gap junction protein, alpha 1 | 0.025 | |
| Apoe | apolipoprotein E | 0.023 | |
| Jak2 | Janus kinase 2 | 0.023 | |
| Pten | phosphatase and tensin homolog | 0.022 | |
| She | src homology 2 domain-containing transforming protein E | 0.022 | |
| Pdgfb | platelet derived growth factor, B polypeptide | 0.022 | |
| Heg1 | HEG homolog 1 (zebrafish) | 0.021 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.021 | |
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.020 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.020 | |
| Tek | endothelial-specific receptor tyrosine kinase | 0.019 | |
| Foxc2 | forkhead box C2 | 0.018 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.018 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.018 | |
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.017 | |
| Arid5b | AT rich interactive domain 5B (MRF1-like) | 0.017 | |
| Ahr | aryl-hydrocarbon receptor | 0.017 | |
| Inpp5d | inositol polyphosphate-5-phosphatase D | 0.016 | |
| Sgpl1 | sphingosine phosphate lyase 1 | 0.016 | |
| Acvrl1 | activin A receptor, type II-like 1 | 0.016 | |
| Psen1 | presenilin 1 | 0.016 | |
| Lyst | lysosomal trafficking regulator | 0.015 | |
| Cacnb2 | calcium channel, voltage-dependent, beta 2 subunit | 0.014 | |
| Ap3b1 | adaptor-related protein complex 3, beta 1 subunit | 0.014 | |
| Nsf | N-ethylmaleimide sensitive fusion protein | 0.014 | |
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.013 | |
| Esam | endothelial cell-specific adhesion molecule | 0.013 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.013 | |
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.013 | |
| Meox2 | mesenchyme homeobox 2 | 0.013 | |
| Flt1 | FMS-like tyrosine kinase 1 | 0.013 | |
| Gnai2 | guanine nucleotide binding protein (G protein), alpha inhibiting 2 | 0.012 | |
| Cxcl12 | chemokine (C-X-C motif) ligand 12 | 0.012 | |
| Jak1 | Janus kinase 1 | 0.012 | |
| Arap3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 | 0.011 | |
| Myo6 | myosin VI | 0.011 | |
| Kif3a | kinesin family member 3A | 0.011 | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.011 | |
| Cav1 | caveolin 1, caveolae protein | 0.011 | |
| Dock7 | dedicator of cytokinesis 7 | 0.011 | |
| Foxp3 | forkhead box P3 | 0.011 | |
| Zcchc10 | zinc finger, CCHC domain containing 10 | 0.011 | |
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.011 | |
| Aplnr | apelin receptor | 0.010 |