The network for 'cellular response to macrophage colony stimulating factor stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to macrophage colony stimulating factor stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.

Name Description Probability Func Analog Organism
VEGFA vascular endothelial growth factor A 0.956
PLCG1 phospholipase C, gamma 1 0.819
GHR growth hormone receptor 0.807
PTPRB protein tyrosine phosphatase, receptor type, B 0.776
NRP1 neuropilin 1 0.768
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.704
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.687
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.576
PDGFA platelet-derived growth factor alpha polypeptide 0.567
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.524
PGF placental growth factor 0.495
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.487
CDH5 cadherin 5, type 2 (vascular endothelium) 0.422
SOS1 son of sevenless homolog 1 (Drosophila) 0.291
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.236
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.223
ZNF746 zinc finger protein 746 0.211
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.205
GAB1 GRB2-associated binding protein 1 0.183
PHYHIPL phytanoyl-CoA 2-hydroxylase interacting protein-like 0.176
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.146
FYN FYN oncogene related to SRC, FGR, YES 0.131
PDGFC platelet derived growth factor C 0.126
FYB FYN binding protein 0.086
INSR insulin receptor 0.073
SLA Src-like-adaptor 0.066
FASLG Fas ligand (TNF superfamily, member 6) 0.065
PTPRJ protein tyrosine phosphatase, receptor type, J 0.057
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.056
KITLG KIT ligand 0.053
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.049
ITGA1 integrin, alpha 1 0.047
GRB7 growth factor receptor-bound protein 7 0.043
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.043
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.039
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.038
GRAP2 GRB2-related adaptor protein 2 0.037
CAV1 caveolin 1, caveolae protein, 22kDa 0.036
BCAR1 breast cancer anti-estrogen resistance 1 0.034
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.032
LAT linker for activation of T cells 0.030
ZNF775 zinc finger protein 775 0.030
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.029
SH2D1A SH2 domain containing 1A 0.028
LDLR low density lipoprotein receptor 0.027
TGFB3 transforming growth factor, beta 3 0.027
ABL2 v-abl Abelson murine leukemia viral oncogene homolog 2 0.024
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.023
FGFR1 fibroblast growth factor receptor 1 0.023
FLT4 fms-related tyrosine kinase 4 0.021
TRIM32 tripartite motif containing 32 0.021
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.020
PARK2 parkinson protein 2, E3 ubiquitin protein ligase (parkin) 0.018
PRKCQ protein kinase C, theta 0.018
VAV1 vav 1 guanine nucleotide exchange factor 0.018
IRS1 insulin receptor substrate 1 0.018
PTEN phosphatase and tensin homolog 0.018
PDE4DIP phosphodiesterase 4D interacting protein 0.017
MAPK8 mitogen-activated protein kinase 8 0.016
PIK3CB phosphoinositide-3-kinase, catalytic, beta polypeptide 0.016
SOCS1 suppressor of cytokine signaling 1 0.016
PIK3CD phosphoinositide-3-kinase, catalytic, delta polypeptide 0.016
CD2 CD2 molecule 0.016
NSF N-ethylmaleimide-sensitive factor 0.016
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.015
CASP10 caspase 10, apoptosis-related cysteine peptidase 0.015
HSPG2 heparan sulfate proteoglycan 2 0.015
ROBO4 roundabout homolog 4, magic roundabout (Drosophila) 0.015
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.015
STAT5A signal transducer and activator of transcription 5A 0.014
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.014
EZR ezrin 0.014
SYK spleen tyrosine kinase 0.013
GAB2 GRB2-associated binding protein 2 0.013
CMIP c-Maf-inducing protein 0.013
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.013
GRB10 growth factor receptor-bound protein 10 0.013
FNBP1 formin binding protein 1 0.013
PTPN9 protein tyrosine phosphatase, non-receptor type 9 0.013
GPR171 G protein-coupled receptor 171 0.012
FAS Fas (TNF receptor superfamily, member 6) 0.012
CD34 CD34 molecule 0.012
PIM1 pim-1 oncogene 0.012
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.012
MAP2 microtubule-associated protein 2 0.012
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.012
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.011
EGFR epidermal growth factor receptor 0.011
TEK TEK tyrosine kinase, endothelial 0.011
EPHB1 EPH receptor B1 0.011
CLDN5 claudin 5 0.011
VEGFC vascular endothelial growth factor C 0.010
JAK2 Janus kinase 2 0.010
CD93 CD93 molecule 0.010
PDE7B phosphodiesterase 7B 0.010
PCDH12 protocadherin 12 0.010
SOCS2 suppressor of cytokine signaling 2 0.010
ENPEP glutamyl aminopeptidase (aminopeptidase A) 0.010
FIGF c-fos induced growth factor (vascular endothelial growth factor D) 0.010
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Vegfa vascular endothelial growth factor A 0.862
Kdr kinase insert domain protein receptor 0.562
Csf1 colony stimulating factor 1 (macrophage) 0.332
Tgfb1 transforming growth factor, beta 1 0.170
Stat3 signal transducer and activator of transcription 3 0.165
Runx2 runt related transcription factor 2 0.139
Ptprb protein tyrosine phosphatase, receptor type, B 0.130
Kitl kit ligand 0.127
Nos3 nitric oxide synthase 3, endothelial cell 0.124
Lepr leptin receptor 0.101
Ldlr low density lipoprotein receptor 0.088
Tgfbr2 transforming growth factor, beta receptor II 0.084
Cdh5 cadherin 5 0.081
Ednrb endothelin receptor type B 0.080
Vhl von Hippel-Lindau tumor suppressor 0.079
Vegfc vascular endothelial growth factor C 0.073
Il6st interleukin 6 signal transducer 0.071
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 0.064
Cdkn1a cyclin-dependent kinase inhibitor 1A (P21) 0.061
Cbl Casitas B-lineage lymphoma 0.061
Flt4 FMS-like tyrosine kinase 4 0.060
Col1a1 collagen, type I, alpha 1 0.059
Zeb1 zinc finger E-box binding homeobox 1 0.057
Efnb2 ephrin B2 0.055
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.053
Ctnnb1 catenin (cadherin associated protein), beta 1 0.049
Apc adenomatosis polyposis coli 0.040
Lyz2 lysozyme 2 0.040
Esr1 estrogen receptor 1 (alpha) 0.039
Fyn Fyn proto-oncogene 0.037
Tiparp TCDD-inducible poly(ADP-ribose) polymerase 0.037
Acvr1 activin A receptor, type 1 0.036
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.034
Trp53 transformation related protein 53 0.034
Mitf microphthalmia-associated transcription factor 0.030
Kit kit oncogene 0.029
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.028
Tmem204 transmembrane protein 204 0.028
Col4a2 collagen, type IV, alpha 2 0.027
Bmp2 bone morphogenetic protein 2 0.026
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.026
Ptch1 patched homolog 1 0.026
Gja1 gap junction protein, alpha 1 0.025
Apoe apolipoprotein E 0.023
Jak2 Janus kinase 2 0.023
Pten phosphatase and tensin homolog 0.022
She src homology 2 domain-containing transforming protein E 0.022
Pdgfb platelet derived growth factor, B polypeptide 0.022
Heg1 HEG homolog 1 (zebrafish) 0.021
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.021
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.020
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.020
Tek endothelial-specific receptor tyrosine kinase 0.019
Foxc2 forkhead box C2 0.018
Pparg peroxisome proliferator activated receptor gamma 0.018
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.018
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.017
Arid5b AT rich interactive domain 5B (MRF1-like) 0.017
Ahr aryl-hydrocarbon receptor 0.017
Inpp5d inositol polyphosphate-5-phosphatase D 0.016
Sgpl1 sphingosine phosphate lyase 1 0.016
Acvrl1 activin A receptor, type II-like 1 0.016
Psen1 presenilin 1 0.016
Lyst lysosomal trafficking regulator 0.015
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit 0.014
Ap3b1 adaptor-related protein complex 3, beta 1 subunit 0.014
Nsf N-ethylmaleimide sensitive fusion protein 0.014
Lrp1 low density lipoprotein receptor-related protein 1 0.013
Esam endothelial cell-specific adhesion molecule 0.013
Notch2 Notch gene homolog 2 (Drosophila) 0.013
Hif1a hypoxia inducible factor 1, alpha subunit 0.013
Meox2 mesenchyme homeobox 2 0.013
Flt1 FMS-like tyrosine kinase 1 0.013
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.012
Cxcl12 chemokine (C-X-C motif) ligand 12 0.012
Jak1 Janus kinase 1 0.012
Arap3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 0.011
Myo6 myosin VI 0.011
Kif3a kinesin family member 3A 0.011
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.011
Cav1 caveolin 1, caveolae protein 0.011
Dock7 dedicator of cytokinesis 7 0.011
Foxp3 forkhead box P3 0.011
Zcchc10 zinc finger, CCHC domain containing 10 0.011
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.011
Aplnr apelin receptor 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism