IMP

Process View

Homo sapiens

27 genes annotated in human

acylglycerol metabolic process

The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "acylglycerol metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "acylglycerol metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
APOA1	apolipoprotein A-I	0.996	Human
ALB	albumin	0.994
HP	haptoglobin	0.877
RNASE4	ribonuclease, RNase A family, 4	0.851	Human
CCNE1	cyclin E1	0.776
APOE	apolipoprotein E	0.758
ANG	angiogenin, ribonuclease, RNase A family, 5	0.727
APOC1	apolipoprotein C-I	0.693
CDK2	cyclin-dependent kinase 2	0.618	Yeast
CREBBP	CREB binding protein	0.527
APOA2	apolipoprotein A-II	0.514
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.490
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.424	Mouse
IDI1	isopentenyl-diphosphate delta isomerase 1	0.414
APOC2	apolipoprotein C-II	0.398
FRS2	fibroblast growth factor receptor substrate 2	0.360
CFB	complement factor B	0.358
AR	androgen receptor	0.347
HMGCS1	3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)	0.342
LDLR	low density lipoprotein receptor	0.334	Mouse
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.312
INSIG1	insulin induced gene 1	0.307	Mouse
APOC3	apolipoprotein C-III	0.295
LCAT	lecithin-cholesterol acyltransferase	0.258
SREBF2	sterol regulatory element binding transcription factor 2	0.244
HMGCR	3-hydroxy-3-methylglutaryl-CoA reductase	0.234
NCOR1	nuclear receptor corepressor 1	0.224
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.220
CFH	complement factor H	0.218
KAT2B	K(lysine) acetyltransferase 2B	0.202
CFI	complement factor I	0.194
GAB1	GRB2-associated binding protein 1	0.190
TTR	transthyretin	0.181
SKP2	S-phase kinase-associated protein 2 (p45)	0.174
A2M	alpha-2-macroglobulin	0.159	Human
GAB2	GRB2-associated binding protein 2	0.148
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.134
MED15	mediator complex subunit 15	0.130
JAK1	Janus kinase 1	0.123
PPARA	peroxisome proliferator-activated receptor alpha	0.121
CAV2	caveolin 2	0.120
HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4	0.109
PECAM1	platelet/endothelial cell adhesion molecule	0.106
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.102
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.096
IRS1	insulin receptor substrate 1	0.085
DHCR7	7-dehydrocholesterol reductase	0.082
RXRA	retinoid X receptor, alpha	0.078
SQLE	squalene epoxidase	0.077
IGF1R	insulin-like growth factor 1 receptor	0.077
ALDOB	aldolase B, fructose-bisphosphate	0.074
UBXN2A	UBX domain protein 2A	0.074
MMS22L	MMS22-like, DNA repair protein	0.073
IFNGR1	interferon gamma receptor 1	0.072
MPZL1	myelin protein zero-like 1	0.072
IL6R	interleukin 6 receptor	0.071
APOB	apolipoprotein B (including Ag(x) antigen)	0.071	Mouse
RNH1	ribonuclease/angiogenin inhibitor 1	0.070
PPARG	peroxisome proliferator-activated receptor gamma	0.066
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.064
RARA	retinoic acid receptor, alpha	0.064
DUSP23	dual specificity phosphatase 23	0.063
LEPR	leptin receptor	0.063
GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.061
JAK2	Janus kinase 2	0.059
AHSG	alpha-2-HS-glycoprotein	0.059
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.056
MDK	midkine (neurite growth-promoting factor 2)	0.056
EHHADH	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	0.055
AGXT2	alanine--glyoxylate aminotransferase 2	0.055
CCDC6	coiled-coil domain containing 6	0.053
ACSL1	acyl-CoA synthetase long-chain family member 1	0.050	Rat
STARD4	StAR-related lipid transfer (START) domain containing 4	0.049
PSEN1	presenilin 1	0.048
CAT	catalase	0.047	Mouse
SC4MOL	sterol-C4-methyl oxidase-like	0.045
C2	complement component 2	0.045
TBL1X	transducin (beta)-like 1X-linked	0.043
HIC1	hypermethylated in cancer 1	0.043
MSTO1	misato homolog 1 (Drosophila)	0.042
INSR	insulin receptor	0.042
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.041
RPL18A	ribosomal protein L18a	0.040
RBP4	retinol binding protein 4, plasma	0.040
AQP7	aquaporin 7	0.040
CLEC4G	C-type lectin domain family 4, member G	0.040
APOA4	apolipoprotein A-IV	0.039
PCSK9	proprotein convertase subtilisin/kexin type 9	0.039
APP	amyloid beta (A4) precursor protein	0.039
NCOA1	nuclear receptor coactivator 1	0.038
INPP5K	inositol polyphosphate-5-phosphatase K	0.032
LIPE	lipase, hormone-sensitive	0.032
TSC22D1	TSC22 domain family, member 1	0.032
FABP4	fatty acid binding protein 4, adipocyte	0.031
CAV1	caveolin 1, caveolae protein, 22kDa	0.031	Mouse
NCOA3	nuclear receptor coactivator 3	0.030
NIPSNAP1	nipsnap homolog 1 (C. elegans)	0.029
STAT1	signal transducer and activator of transcription 1, 91kDa	0.029
FGA	fibrinogen alpha chain	0.028
TF	transferrin	0.028
TNIK	TRAF2 and NCK interacting kinase	0.028
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.028
CPB2	carboxypeptidase B2 (plasma)	0.028
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.027
CA5A	carbonic anhydrase VA, mitochondrial	0.027
IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	0.026
CFD	complement factor D (adipsin)	0.026
CTNNBIP1	catenin, beta interacting protein 1	0.026
F7	coagulation factor VII (serum prothrombin conversion accelerator)	0.026
PTPRF	protein tyrosine phosphatase, receptor type, F	0.026
FDFT1	farnesyl-diphosphate farnesyltransferase 1	0.025
FBXW11	F-box and WD repeat domain containing 11	0.025
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.024
ECSIT	ECSIT homolog (Drosophila)	0.024
CYB5A	cytochrome b5 type A (microsomal)	0.024
AGXT	alanine-glyoxylate aminotransferase	0.024
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.024
PDK4	pyruvate dehydrogenase kinase, isozyme 4	0.023
PLTP	phospholipid transfer protein	0.023
LPA	lipoprotein, Lp(a)	0.023
TRIM11	tripartite motif containing 11	0.023
SOD2	superoxide dismutase 2, mitochondrial	0.023
EDF1	endothelial differentiation-related factor 1	0.023
PAH	phenylalanine hydroxylase	0.022
SERPING1	serpin peptidase inhibitor, clade G (C1 inhibitor), member 1	0.022
HPX	hemopexin	0.022
CD302	CD302 molecule	0.022
BTRC	beta-transducin repeat containing	0.022
CCNG2	cyclin G2	0.021
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.021
PLG	plasminogen	0.021
ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	0.021
MAP4K5	mitogen-activated protein kinase kinase kinase kinase 5	0.021
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.021
THRSP	thyroid hormone responsive	0.021
AGPAT2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.020
FOXO1	forkhead box O1	0.020
MED26	mediator complex subunit 26	0.020
DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	0.020
KNG1	kininogen 1	0.020
GLIS2	GLIS family zinc finger 2	0.020
HADHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	0.020
CD36	CD36 molecule (thrombospondin receptor)	0.020	Rat
CCND1	cyclin D1	0.020
GPLD1	glycosylphosphatidylinositol specific phospholipase D1	0.020	Mouse
CLEC3B	C-type lectin domain family 3, member B	0.019
CREB1	cAMP responsive element binding protein 1	0.019
IREB2	iron-responsive element binding protein 2	0.019
FOXM1	forkhead box M1	0.019
CCNB2	cyclin B2	0.019
EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)	0.019
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.019
FAM20C	family with sequence similarity 20, member C	0.019
GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)	0.019
F2R	coagulation factor II (thrombin) receptor	0.019
EP300	E1A binding protein p300	0.018
CLDN5	claudin 5	0.017
TST	thiosulfate sulfurtransferase (rhodanese)	0.017
CUL1	cullin 1	0.017
PTEN	phosphatase and tensin homolog	0.017
TXNRD1	thioredoxin reductase 1	0.017
CNOT6	CCR4-NOT transcription complex, subunit 6	0.017
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.017
LIFR	leukemia inhibitory factor receptor alpha	0.016
NAMPT	nicotinamide phosphoribosyltransferase	0.016
ALAS1	aminolevulinate, delta-, synthase 1	0.016
ACAA1	acetyl-CoA acyltransferase 1	0.016
CCNA2	cyclin A2	0.016
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.016
TWIST2	twist homolog 2 (Drosophila)	0.016
ITIH1	inter-alpha (globulin) inhibitor H1	0.016
EMD	emerin	0.016
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.016
ANXA4	annexin A4	0.015
OPLAH	5-oxoprolinase (ATP-hydrolysing)	0.015
MBNL1	muscleblind-like (Drosophila)	0.015
PLIN1	perilipin 1	0.015
C8G	complement component 8, gamma polypeptide	0.015
VSIG4	V-set and immunoglobulin domain containing 4	0.015
ETFB	electron-transfer-flavoprotein, beta polypeptide	0.015
FOXO3	forkhead box O3	0.015
GRB10	growth factor receptor-bound protein 10	0.015
G6PC	glucose-6-phosphatase, catalytic subunit	0.015
MTTP	microsomal triglyceride transfer protein	0.015
SDPR	serum deprivation response	0.015
HBP1	HMG-box transcription factor 1	0.015
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.015	Rat
LRP1	low density lipoprotein receptor-related protein 1	0.015
SEPT8	septin 8	0.015
MBNL2	muscleblind-like 2 (Drosophila)	0.014
CD33	CD33 molecule	0.014
RYK	RYK receptor-like tyrosine kinase	0.014
SPRED1	sprouty-related, EVH1 domain containing 1	0.014
CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1	0.014
ASGR2	asialoglycoprotein receptor 2	0.014
ADH6	alcohol dehydrogenase 6 (class V)	0.014
AIP	aryl hydrocarbon receptor interacting protein	0.014
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.014
PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)	0.014
PC	pyruvate carboxylase	0.014
IRS2	insulin receptor substrate 2	0.014
CP	ceruloplasmin (ferroxidase)	0.014
FBXO33	F-box protein 33	0.014
SLC38A2	solute carrier family 38, member 2	0.014
OTC	ornithine carbamoyltransferase	0.014
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.014
FABP1	fatty acid binding protein 1, liver	0.013
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.013
CYP3A4	cytochrome P450, family 3, subfamily A, polypeptide 4	0.013
CYP27A1	cytochrome P450, family 27, subfamily A, polypeptide 1	0.013
TDGF1	teratocarcinoma-derived growth factor 1	0.013
CIDEC	cell death-inducing DFFA-like effector c	0.013
BHMT	betaine--homocysteine S-methyltransferase	0.013
CRAT	carnitine O-acetyltransferase	0.013
PON1	paraoxonase 1	0.013
GLYAT	glycine-N-acyltransferase	0.013
ASGR1	asialoglycoprotein receptor 1	0.013
FLT3	fms-related tyrosine kinase 3	0.013
SKP1	S-phase kinase-associated protein 1	0.013
DLG1	discs, large homolog 1 (Drosophila)	0.012
HNMT	histamine N-methyltransferase	0.012
ACAA2	acetyl-CoA acyltransferase 2	0.012
ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	0.012
PLIN4	perilipin 4	0.012
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.012
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.012
SEPP1	selenoprotein P, plasma, 1	0.012
EDNRB	endothelin receptor type B	0.012
PRAM1	PML-RARA regulated adaptor molecule 1	0.012
APOC4	apolipoprotein C-IV	0.012
MGST1	microsomal glutathione S-transferase 1	0.012
KYNU	kynureninase	0.012
APCS	amyloid P component, serum	0.012
CDK6	cyclin-dependent kinase 6	0.012
ACACA	acetyl-CoA carboxylase alpha	0.012
AOX1	aldehyde oxidase 1	0.012
C8B	complement component 8, beta polypeptide	0.012
FAM83C	family with sequence similarity 83, member C	0.012
C4BPB	complement component 4 binding protein, beta	0.012
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.012
PKLR	pyruvate kinase, liver and RBC	0.012
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.012
F2	coagulation factor II (thrombin)	0.011
AQR	aquarius homolog (mouse)	0.011
C1S	complement component 1, s subcomponent	0.011
F11	coagulation factor XI	0.011
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.011
BHLHE40	basic helix-loop-helix family, member e40	0.011
SCARB1	scavenger receptor class B, member 1	0.011	Mouse
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.011
ARG1	arginase, liver	0.011
HABP2	hyaluronan binding protein 2	0.011
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.011
HPD	4-hydroxyphenylpyruvate dioxygenase	0.011
NR1H3	nuclear receptor subfamily 1, group H, member 3	0.011
PTPRB	protein tyrosine phosphatase, receptor type, B	0.011
MED25	mediator complex subunit 25	0.011
LPL	lipoprotein lipase	0.011
FABP2	fatty acid binding protein 2, intestinal	0.011
SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	0.011
CIDEA	cell death-inducing DFFA-like effector a	0.011
PTPN5	protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)	0.011
CD2BP2	CD2 (cytoplasmic tail) binding protein 2	0.011
GBF1	golgi brefeldin A resistant guanine nucleotide exchange factor 1	0.011
RHOQ	ras homolog gene family, member Q	0.011
ADIPOQ	adiponectin, C1Q and collagen domain containing	0.011
MAOA	monoamine oxidase A	0.011
RAB8B	RAB8B, member RAS oncogene family	0.011
SNX27	sorting nexin family member 27	0.011
FAM114A1	family with sequence similarity 114, member A1	0.011
SLC31A2	solute carrier family 31 (copper transporters), member 2	0.010
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.010
SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10	0.010
PRKCA	protein kinase C, alpha	0.010
MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)	0.010
VTN	vitronectin	0.010
OGFR	opioid growth factor receptor	0.010
GPX3	glutathione peroxidase 3 (plasma)	0.010