IMP

Process View

Homo sapiens

3 genes annotated in human

inflammatory cell apoptotic process

Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "inflammatory cell apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "inflammatory cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.658
CCR5	chemokine (C-C motif) receptor 5	0.638	Mouse
FASLG	Fas ligand (TNF superfamily, member 6)	0.491
DERL1	Der1-like domain family, member 1	0.476
EP300	E1A binding protein p300	0.296
FADD	Fas (TNFRSF6)-associated via death domain	0.266
CCL5	chemokine (C-C motif) ligand 5	0.238	Mouse
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.222
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.210
MSN	moesin	0.198
HDAC4	histone deacetylase 4	0.147
IL6R	interleukin 6 receptor	0.137
CAV1	caveolin 1, caveolae protein, 22kDa	0.121
VCP	valosin containing protein	0.094
CFLAR	CASP8 and FADD-like apoptosis regulator	0.089
CAV2	caveolin 2	0.072
SYK	spleen tyrosine kinase	0.070
CXCR4	chemokine (C-X-C motif) receptor 4	0.060
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.050
ANXA5	annexin A5	0.042
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.040
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.039
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.037
HDAC9	histone deacetylase 9	0.034
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.034
KAT2B	K(lysine) acetyltransferase 2B	0.033
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.031
CCR1	chemokine (C-C motif) receptor 1	0.031
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.029
CXCR6	chemokine (C-X-C motif) receptor 6	0.029
CDK6	cyclin-dependent kinase 6	0.029
IL8	interleukin 8	0.027
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.026
CSF1R	colony stimulating factor 1 receptor	0.024
PROCR	protein C receptor, endothelial	0.023
BID	BH3 interacting domain death agonist	0.023
VCAM1	vascular cell adhesion molecule 1	0.023
MEF2A	myocyte enhancer factor 2A	0.021
CLEC7A	C-type lectin domain family 7, member A	0.021
AHR	aryl hydrocarbon receptor	0.021
IL1R2	interleukin 1 receptor, type II	0.020
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	0.020
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.020
PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	0.020
CCND3	cyclin D3	0.019
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.018
FN1	fibronectin 1	0.017
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.017
RAD52	RAD52 homolog (S. cerevisiae)	0.017
CREBBP	CREB binding protein	0.017
EZR	ezrin	0.017
CLEC4A	C-type lectin domain family 4, member A	0.016
DERL2	Der1-like domain family, member 2	0.016
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.016
SMAD7	SMAD family member 7	0.016
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.016
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.016
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.015
GPR171	G protein-coupled receptor 171	0.015
CCL4	chemokine (C-C motif) ligand 4	0.015
SPTBN1	spectrin, beta, non-erythrocytic 1	0.015
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.015
CLEC2B	C-type lectin domain family 2, member B	0.015
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.015
CCL2	chemokine (C-C motif) ligand 2	0.015
GLIPR1	GLI pathogenesis-related 1	0.014
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.014
GIMAP4	GTPase, IMAP family member 4	0.014
RUNX1	runt-related transcription factor 1	0.013
ANXA2	annexin A2	0.013
SLAMF1	signaling lymphocytic activation molecule family member 1	0.013
STK17A	serine/threonine kinase 17a	0.013
TFEC	transcription factor EC	0.013
SLAMF7	SLAM family member 7	0.013
PRKCDBP	protein kinase C, delta binding protein	0.013
EVI2A	ecotropic viral integration site 2A	0.013
SRGN	serglycin	0.013
INADL	InaD-like (Drosophila)	0.013
PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	0.013
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.013
SLC7A11	solute carrier family 7, (cationic amino acid transporter, y+ system) member 11	0.012
RRP8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	0.012
GPR109B	G protein-coupled receptor 109B	0.012
IL7R	interleukin 7 receptor	0.012
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.012
FGL2	fibrinogen-like 2	0.012
CXCL9	chemokine (C-X-C motif) ligand 9	0.012
DPP4	dipeptidyl-peptidase 4	0.012
CXCL10	chemokine (C-X-C motif) ligand 10	0.012
IFNG	interferon, gamma	0.011
CCR2	chemokine (C-C motif) receptor 2	0.011	Mouse
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.011
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.011
IL18R1	interleukin 18 receptor 1	0.011
CD72	CD72 molecule	0.011
TLR7	toll-like receptor 7	0.011
CD59	CD59 molecule, complement regulatory protein	0.011
DUSP10	dual specificity phosphatase 10	0.011
FOXO3	forkhead box O3	0.011
GPR65	G protein-coupled receptor 65	0.011
CXCR2	chemokine (C-X-C motif) receptor 2	0.011	Rat
IGSF6	immunoglobulin superfamily, member 6	0.011
CD69	CD69 molecule	0.011
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.011
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.011
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.011
STK17B	serine/threonine kinase 17b	0.011
HIPK2	homeodomain interacting protein kinase 2	0.011
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.011
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.011
IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides	0.011
SELL	selectin L	0.010
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.010
IRF2	interferon regulatory factor 2	0.010
S100A10	S100 calcium binding protein A10	0.010
EMP1	epithelial membrane protein 1	0.010
IL4R	interleukin 4 receptor	0.010
CCND1	cyclin D1	0.010
PTEN	phosphatase and tensin homolog	0.010
TSPYL1	TSPY-like 1	0.010
PLEK	pleckstrin	0.010
MAPK7	mitogen-activated protein kinase 7	0.010
CD53	CD53 molecule	0.010
HRH1	histamine receptor H1	0.010