IMP

Process View

Homo sapiens

29 genes annotated in human

positive regulation of cytokinesis

Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.

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Known genes in the process in human Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of cytokinesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "positive regulation of cytokinesis" (in gray)

Name	Description	Probability	Func Analog Organism
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.964
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.808	Human
CCR5	chemokine (C-C motif) receptor 5	0.556	Human
NCF1	neutrophil cytosolic factor 1	0.482
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.459
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.447
KIF23	kinesin family member 23	0.384
ARHGAP1	Rho GTPase activating protein 1	0.375
ADORA2A	adenosine A2a receptor	0.340
MARK3	MAP/microtubule affinity-regulating kinase 3	0.325
CCL5	chemokine (C-C motif) ligand 5	0.324
NCF4	neutrophil cytosolic factor 4, 40kDa	0.322
CCNB2	cyclin B2	0.255
GAS2L3	growth arrest-specific 2 like 3	0.238
TPBG	trophoblast glycoprotein	0.138
CDK1	cyclin-dependent kinase 1	0.129
KRT18	keratin 18	0.122
PRC1	protein regulator of cytokinesis 1	0.119
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.119
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.103
INCENP	inner centromere protein antigens 135/155kDa	0.103
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.100
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.094
CDT1	chromatin licensing and DNA replication factor 1	0.094
CCL22	chemokine (C-C motif) ligand 22	0.092
CCR4	chemokine (C-C motif) receptor 4	0.092	Human
IFNG	interferon, gamma	0.087
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.081
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.081
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.080
CCNA2	cyclin A2	0.078
TYRP1	tyrosinase-related protein 1	0.078
CCR2	chemokine (C-C motif) receptor 2	0.077	Human
CDC7	cell division cycle 7 homolog (S. cerevisiae)	0.072
SOS1	son of sevenless homolog 1 (Drosophila)	0.071
KRT14	keratin 14	0.070
CDCA8	cell division cycle associated 8	0.069
BIRC5	baculoviral IAP repeat containing 5	0.069
LAD1	ladinin 1	0.065
PRKCA	protein kinase C, alpha	0.064	Human
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.064
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.063
AURKB	aurora kinase B	0.062
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.061
CXCR3	chemokine (C-X-C motif) receptor 3	0.060	Human
SEC31A	SEC31 homolog A (S. cerevisiae)	0.060
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.059
CDK2	cyclin-dependent kinase 2	0.058
JUP	junction plakoglobin	0.058
CYBA	cytochrome b-245, alpha polypeptide	0.058
EZR	ezrin	0.057
NCF2	neutrophil cytosolic factor 2	0.052
IL2RB	interleukin 2 receptor, beta	0.051
NCK1	NCK adaptor protein 1	0.050
KRT5	keratin 5	0.050
KRT8	keratin 8	0.048
ORC1	origin recognition complex, subunit 1	0.048
RICTOR	RPTOR independent companion of MTOR, complex 2	0.046
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.046
CD40LG	CD40 ligand	0.044
SFN	stratifin	0.044
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.042
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.040
IRS1	insulin receptor substrate 1	0.039
TIMP3	TIMP metallopeptidase inhibitor 3	0.039
CENPE	centromere protein E, 312kDa	0.039
CCNB1	cyclin B1	0.039
FRMD5	FERM domain containing 5	0.038
KIF4A	kinesin family member 4A	0.038
RAB11FIP1	RAB11 family interacting protein 1 (class I)	0.036
FOXM1	forkhead box M1	0.036
INSR	insulin receptor	0.035
CBX5	chromobox homolog 5	0.034
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.033
RACGAP1	Rac GTPase activating protein 1	0.032
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.032
EGFR	epidermal growth factor receptor	0.031
ORC2	origin recognition complex, subunit 2	0.031
GRB10	growth factor receptor-bound protein 10	0.031
CXCR6	chemokine (C-X-C motif) receptor 6	0.031	Human
RHOG	ras homolog gene family, member G (rho G)	0.030	Human
CCDC85B	coiled-coil domain containing 85B	0.030
DSP	desmoplakin	0.028
ZYX	zyxin	0.028
CEP55	centrosomal protein 55kDa	0.027
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.026
MAPK12	mitogen-activated protein kinase 12	0.026
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.026	Human
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.026
SNX9	sorting nexin 9	0.026
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.025
WEE1	WEE1 homolog (S. pombe)	0.025
CCR8	chemokine (C-C motif) receptor 8	0.025	Human
SPRR2D	small proline-rich protein 2D	0.025
CCNE1	cyclin E1	0.024
CCR7	chemokine (C-C motif) receptor 7	0.024	Human
RAB11FIP3	RAB11 family interacting protein 3 (class II)	0.024
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.024
ARHGAP26	Rho GTPase activating protein 26	0.023
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.023
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.023
PRKCZ	protein kinase C, zeta	0.023
RHOC	ras homolog gene family, member C	0.023	Human
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.022
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.022
ERBB2IP	erbb2 interacting protein	0.022
EMP3	epithelial membrane protein 3	0.022
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.021
ZNF282	zinc finger protein 282	0.021
TRIM9	tripartite motif containing 9	0.021
CCL3	chemokine (C-C motif) ligand 3	0.021
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.020
HDAC5	histone deacetylase 5	0.020
PTN	pleiotrophin	0.020
CENPF	centromere protein F, 350/400kDa (mitosin)	0.020
ADRBK1	adrenergic, beta, receptor kinase 1	0.019
CENPI	centromere protein I	0.019
CKS2	CDC28 protein kinase regulatory subunit 2	0.019
GRB2	growth factor receptor-bound protein 2	0.018
DSG2	desmoglein 2	0.018
CXCR4	chemokine (C-X-C motif) receptor 4	0.018	Human
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.018
HJURP	Holliday junction recognition protein	0.018
ECT2	epithelial cell transforming sequence 2 oncogene	0.018
KIF18A	kinesin family member 18A	0.018
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.017
ARF6	ADP-ribosylation factor 6	0.017
CDKN3	cyclin-dependent kinase inhibitor 3	0.017
USP8	ubiquitin specific peptidase 8	0.017
TAS1R3	taste receptor, type 1, member 3	0.017	Human
CLSPN	claspin	0.017
ABI1	abl-interactor 1	0.017
SH2D3A	SH2 domain containing 3A	0.016
OPRD1	opioid receptor, delta 1	0.016	Human
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.016
SGOL1	shugoshin-like 1 (S. pombe)	0.016
CTTN	cortactin	0.016
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.016
RBL1	retinoblastoma-like 1 (p107)	0.016
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.015
SELL	selectin L	0.015
FASLG	Fas ligand (TNF superfamily, member 6)	0.015
C19orf25	chromosome 19 open reading frame 25	0.015
HDAC6	histone deacetylase 6	0.015
TRIP10	thyroid hormone receptor interactor 10	0.015
IL4	interleukin 4	0.015
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.015
CCNE2	cyclin E2	0.015
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.015
MPDZ	multiple PDZ domain protein	0.015
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.014
TRAF3IP3	TRAF3 interacting protein 3	0.014
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.014
PRKCD	protein kinase C, delta	0.014
CXCR2	chemokine (C-X-C motif) receptor 2	0.014	Human
CDH15	cadherin 15, type 1, M-cadherin (myotubule)	0.013
DSG1	desmoglein 1	0.013
CXCR1	chemokine (C-X-C motif) receptor 1	0.013	Human
CCR9	chemokine (C-C motif) receptor 9	0.013	Human
BDKRB1	bradykinin receptor B1	0.013	Human
IRS2	insulin receptor substrate 2	0.013
TNS4	tensin 4	0.013
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.013
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.013
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.013
JUND	jun D proto-oncogene	0.013
CEACAM3	carcinoembryonic antigen-related cell adhesion molecule 3	0.012
CCL7	chemokine (C-C motif) ligand 7	0.012
CCL11	chemokine (C-C motif) ligand 11	0.012
OSGEP	O-sialoglycoprotein endopeptidase	0.012
CCR6	chemokine (C-C motif) receptor 6	0.012	Human
ARHGAP11A	Rho GTPase activating protein 11A	0.012
SLAMF7	SLAM family member 7	0.012
OR1G1	olfactory receptor, family 1, subfamily G, member 1	0.012
RHOD	ras homolog gene family, member D	0.012
GSG2	germ cell associated 2 (haspin)	0.012
DEPDC1	DEP domain containing 1	0.012
SIGLEC6	sialic acid binding Ig-like lectin 6	0.012
EPS8	epidermal growth factor receptor pathway substrate 8	0.012
IL1F5	interleukin 1 family, member 5 (delta)	0.012
PLD1	phospholipase D1, phosphatidylcholine-specific	0.012
MPRIP	myosin phosphatase Rho interacting protein	0.011
PNPLA6	patatin-like phospholipase domain containing 6	0.011
ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1	0.011
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.011
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.011
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.011
DSG3	desmoglein 3	0.011
RHOA	ras homolog gene family, member A	0.011
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.011	Human
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.011
CUL1	cullin 1	0.011
TIMELESS	timeless homolog (Drosophila)	0.011
SORBS2	sorbin and SH3 domain containing 2	0.011
CENPA	centromere protein A	0.011
SHCBP1	SHC SH2-domain binding protein 1	0.011
RLN3	relaxin 3	0.011
KLF2	Kruppel-like factor 2 (lung)	0.011
PLK1	polo-like kinase 1	0.011
APC	adenomatous polyposis coli	0.011
RALBP1	ralA binding protein 1	0.010
CXCR5	chemokine (C-X-C motif) receptor 5	0.010
CXCL9	chemokine (C-X-C motif) ligand 9	0.010
GTSE1	G-2 and S-phase expressed 1	0.010
LMO4	LIM domain only 4	0.010
MC5R	melanocortin 5 receptor	0.010
CLEC4E	C-type lectin domain family 4, member E	0.010
S100A14	S100 calcium binding protein A14	0.010
CD28	CD28 molecule	0.010
GPRIN2	G protein regulated inducer of neurite outgrowth 2	0.010
PPL	periplakin	0.010
SLAMF6	SLAM family member 6	0.010
CXCL13	chemokine (C-X-C motif) ligand 13	0.010
SNAP25	synaptosomal-associated protein, 25kDa	0.010
CLEC4A	C-type lectin domain family 4, member A	0.010
PSEN1	presenilin 1	0.010
CLDN16	claudin 16	0.010
CD97	CD97 molecule	0.010