IMP

Process View

Mus musculus

4 genes annotated in mouse

negative regulation of triglyceride metabolic process

Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of triglyceride metabolic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "negative regulation of triglyceride metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
Ar	androgen receptor	0.926
Lepr	leptin receptor	0.913
Irs2	insulin receptor substrate 2	0.867
Lep	leptin	0.729
Prlr	prolactin receptor	0.721
Kiss1	KiSS-1 metastasis-suppressor	0.709
Ghr	growth hormone receptor	0.660
Pnpla2	patatin-like phospholipase domain containing 2	0.511
Insr	insulin receptor	0.472
Pten	phosphatase and tensin homolog	0.262
Pparg	peroxisome proliferator activated receptor gamma	0.222
Kiss1r	KISS1 receptor	0.208
Amhr2	anti-Mullerian hormone type 2 receptor	0.166
Nos1	nitric oxide synthase 1, neuronal	0.140
Stat5a	signal transducer and activator of transcription 5A	0.086
Epn1	epsin 1	0.081
Vdr	vitamin D receptor	0.081
Abhd5	abhydrolase domain containing 5	0.077
Ncoa6	nuclear receptor coactivator 6	0.074
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.066
Ahr	aryl-hydrocarbon receptor	0.058
Nos3	nitric oxide synthase 3, endothelial cell	0.057
Vgf	VGF nerve growth factor inducible	0.055
Inha	inhibin alpha	0.051
Fshr	follicle stimulating hormone receptor	0.047
Gnrh1	gonadotropin releasing hormone 1	0.046
Egr1	early growth response 1	0.046
Tgfb1	transforming growth factor, beta 1	0.042
Rxra	retinoid X receptor alpha	0.042
Adipor2	adiponectin receptor 2	0.040
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.040
Samd4b	sterile alpha motif domain containing 4B	0.039
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.039
Prkce	protein kinase C, epsilon	0.038
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.037
Jag2	jagged 2	0.035
Mark2	MAP/microtubule affinity-regulating kinase 2	0.034	Mouse
Klc2	kinesin light chain 2	0.034
Bglap	bone gamma carboxyglutamate protein	0.032
Tbc1d4	TBC1 domain family, member 4	0.030
Fbrs	fibrosin	0.029
Dlg4	discs, large homolog 4 (Drosophila)	0.029
Cdkn1b	cyclin-dependent kinase inhibitor 1B	0.028
Nhlh2	nescient helix loop helix 2	0.027
Zfp592	zinc finger protein 592	0.026
Npc1	Niemann Pick type C1	0.026
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.026
Ncoa3	nuclear receptor coactivator 3	0.025
Hgs	HGF-regulated tyrosine kinase substrate	0.024
Pias4	protein inhibitor of activated STAT 4	0.024
Adra1b	adrenergic receptor, alpha 1b	0.024
Cadm4	cell adhesion molecule 4	0.023
Spen	SPEN homolog, transcriptional regulator (Drosophila)	0.023
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.022
Auts2	autism susceptibility candidate 2	0.022
Atg2a	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.022
Mkl1	MKL (megakaryoblastic leukemia)/myocardin-like 1	0.022
Baz2a	bromodomain adjacent to zinc finger domain, 2A	0.022
Arid5b	AT rich interactive domain 5B (MRF1-like)	0.022
Celsr2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.021
Cyhr1	cysteine and histidine rich 1	0.021
Ap2a1	adaptor protein complex AP-2, alpha 1 subunit	0.021
Npy1r	neuropeptide Y receptor Y1	0.021
Vegfa	vascular endothelial growth factor A	0.021
Nefm	neurofilament, medium polypeptide	0.020
Per1	period homolog 1 (Drosophila)	0.020
Stat5b	signal transducer and activator of transcription 5B	0.019
Fst	follistatin	0.019
Trim8	tripartite motif-containing 8	0.019
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.018
Thra	thyroid hormone receptor alpha	0.018
Camsap1	calmodulin regulated spectrin-associated protein 1	0.018
Src	Rous sarcoma oncogene	0.018
Fam100a	family with sequence similarity 100, member A	0.018
Homer1	homer homolog 1 (Drosophila)	0.018
Mink1	misshapen-like kinase 1 (zebrafish)	0.017
Ncoa1	nuclear receptor coactivator 1	0.017
Pim3	proviral integration site 3	0.017
Pura	purine rich element binding protein A	0.016
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.016
Ywhaz	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.016
Dusp8	dual specificity phosphatase 8	0.016
Wbp7	WW domain binding protein 7	0.016
Tmem205	transmembrane protein 205	0.016
Drd2	dopamine receptor D2	0.015
Hipk2	homeodomain interacting protein kinase 2	0.015
Dnajb5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.015
Pptc7	PTC7 protein phosphatase homolog (S. cerevisiae)	0.015
Sox9	SRY-box containing gene 9	0.015
Igf1	insulin-like growth factor 1	0.015
Cacng4	calcium channel, voltage-dependent, gamma subunit 4	0.014
Ube2o	ubiquitin-conjugating enzyme E2O	0.014
Smagp	small cell adhesion glycoprotein	0.014
Med13l	mediator complex subunit 13-like	0.014
Gsk3a	glycogen synthase kinase 3 alpha	0.014
Apoe	apolipoprotein E	0.014
Slc4a4	solute carrier family 4 (anion exchanger), member 4	0.014
Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	0.014
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.014
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.014
Git1	G protein-coupled receptor kinase-interactor 1	0.014
Ksr1	kinase suppressor of ras 1	0.014
Pcsk7	proprotein convertase subtilisin/kexin type 7	0.013
Tbc1d22b	TBC1 domain family, member 22B	0.013
Shank3	SH3/ankyrin domain gene 3	0.013
Slc9a1	solute carrier family 9 (sodium/hydrogen exchanger), member 1	0.013
Ulk1	Unc-51 like kinase 1 (C. elegans)	0.013
Npepps	aminopeptidase puromycin sensitive	0.013
Enah	enabled homolog (Drosophila)	0.013
Msl1	male-specific lethal 1 homolog (Drosophila)	0.013
Kit	kit oncogene	0.013
Zbtb7a	zinc finger and BTB domain containing 7a	0.013
Cacna1g	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.013
Supt6h	suppressor of Ty 6 homolog (S. cerevisiae)	0.012
Esr1	estrogen receptor 1 (alpha)	0.012	Rat
Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	0.012
Gpr56	G protein-coupled receptor 56	0.012
Stim1	stromal interaction molecule 1	0.012
Brd2	bromodomain containing 2	0.012
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.012
Hsf2	heat shock factor 2	0.012
Adipoq	adiponectin, C1Q and collagen domain containing	0.012
Smg7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.012
Eif4ebp2	eukaryotic translation initiation factor 4E binding protein 2	0.012
Mef2d	myocyte enhancer factor 2D	0.012
Nr4a1	nuclear receptor subfamily 4, group A, member 1	0.011
Cyp19a1	cytochrome P450, family 19, subfamily a, polypeptide 1	0.011
Wbp2	WW domain binding protein 2	0.011
Lmtk2	lemur tyrosine kinase 2	0.011
Cnr1	cannabinoid receptor 1 (brain)	0.011
Grip1	glutamate receptor interacting protein 1	0.011
Jup	junction plakoglobin	0.011
Foxo3	forkhead box O3	0.011
Inhbb	inhibin beta-B	0.011
Znrf1	zinc and ring finger 1	0.011
Lhx9	LIM homeobox protein 9	0.011
Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	0.011
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.011
Atxn7l3	ataxin 7-like 3	0.011
Zfp687	zinc finger protein 687	0.011
Mark4	MAP/microtubule affinity-regulating kinase 4	0.011	Mouse
Ncor2	nuclear receptor co-repressor 2	0.011
Dusp1	dual specificity phosphatase 1	0.011
Rc3h1	RING CCCH (C3H) domains 1	0.011
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.011
Dgat2	diacylglycerol O-acyltransferase 2	0.011
Irs1	insulin receptor substrate 1	0.011
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.011
Cdk11b	cyclin-dependent kinase 11B	0.011
Arl8a	ADP-ribosylation factor-like 8A	0.011
Rab6b	RAB6B, member RAS oncogene family	0.011
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.011
Atxn2l	ataxin 2-like	0.011
Tob2	transducer of ERBB2, 2	0.011
Cic	capicua homolog (Drosophila)	0.011
Mllt6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.011
Lsm14b	LSM14 homolog B (SCD6, S. cerevisiae)	0.010
Tubb3	tubulin, beta 3	0.010
Stk40	serine/threonine kinase 40	0.010
Larp4b	La ribonucleoprotein domain family, member 4B	0.010
Grik5	glutamate receptor, ionotropic, kainate 5 (gamma 2)	0.010
Ctdnep1	CTD nuclear envelope phosphatase 1	0.010
Fosl2	fos-like antigen 2	0.010
Stat3	signal transducer and activator of transcription 3	0.010
Syt7	synaptotagmin VII	0.010
Zfp385a	zinc finger protein 385A	0.010
Pcdh1	protocadherin 1	0.010
Fbf1	Fas (TNFRSF6) binding factor 1	0.010
Rasd2	RASD family, member 2	0.010
Gpd2	glycerol phosphate dehydrogenase 2, mitochondrial	0.010
Akt2	thymoma viral proto-oncogene 2	0.010
Sec14l1	SEC14-like 1 (S. cerevisiae)	0.010
Lpin1	lipin 1	0.010
Slc24a3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	0.010
Smad3	MAD homolog 3 (Drosophila)	0.010
Pafah2	platelet-activating factor acetylhydrolase 2	0.010