IMP
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Mus musculus
0 genes annotated in mouse
lipid storage disease
DOID:9455
A lysosomal storage disease that involves the accumulation of harmful amounts of lipids (fats) in some of the body's cells and tissues.
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In addition to gene-name show these genes:
Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in mouse and predicted with the mouse functional network.
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Lamp1 | lysosomal-associated membrane protein 1 | 0.984 | ||
| Hexa | hexosaminidase A | 0.983 | Human | |
| Ctsb | cathepsin B | 0.972 | ||
| Hexb | hexosaminidase B | 0.966 | Human | |
| 0610031J06Rik | RIKEN cDNA 0610031J06 gene | 0.940 | ||
| Gns | glucosamine (N-acetyl)-6-sulfatase | 0.905 | ||
| Npc2 | Niemann Pick type C2 | 0.878 | Human | |
| Dpp7 | dipeptidylpeptidase 7 | 0.849 | ||
| Psap | prosaposin | 0.832 | Human | |
| Lgmn | legumain | 0.827 | ||
| Ctsd | cathepsin D | 0.820 | Human | |
| Ctsa | cathepsin A | 0.786 | ||
| Gba | glucosidase, beta, acid | 0.777 | Human | |
| Grn | granulin | 0.764 | Human | |
| Tpp1 | tripeptidyl peptidase I | 0.700 | Human | |
| Coro1b | coronin, actin binding protein 1B | 0.502 | ||
| Atp6ap1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.480 | ||
| Ctsz | cathepsin Z | 0.457 | ||
| Pld3 | phospholipase D family, member 3 | 0.442 | ||
| Mfsd1 | major facilitator superfamily domain containing 1 | 0.352 | ||
| Itm2c | integral membrane protein 2C | 0.281 | ||
| Lamp2 | lysosomal-associated membrane protein 2 | 0.266 | ||
| Tcn2 | transcobalamin 2 | 0.259 | ||
| Idua | iduronidase, alpha-L- | 0.246 | ||
| Asah1 | N-acylsphingosine amidohydrolase 1 | 0.226 | Human | |
| Atp6v0d1 | ATPase, H+ transporting, lysosomal V0 subunit D1 | 0.208 | ||
| Naga | N-acetyl galactosaminidase, alpha | 0.203 | ||
| Gusb | glucuronidase, beta | 0.195 | ||
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.170 | ||
| Man2b1 | mannosidase 2, alpha B1 | 0.155 | ||
| Lrp1 | low density lipoprotein receptor-related protein 1 | 0.149 | ||
| Naglu | alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) | 0.146 | ||
| Pold4 | polymerase (DNA-directed), delta 4 | 0.145 | ||
| Dscr3 | Down syndrome critical region gene 3 | 0.133 | ||
| Ghr | growth hormone receptor | 0.121 | ||
| Atp6v0b | ATPase, H+ transporting, lysosomal V0 subunit B | 0.121 | ||
| Rragc | Ras-related GTP binding C | 0.121 | ||
| Prnp | prion protein | 0.118 | ||
| Lyz2 | lysozyme 2 | 0.111 | ||
| Manba | mannosidase, beta A, lysosomal | 0.108 | ||
| Soat1 | sterol O-acyltransferase 1 | 0.100 | ||
| Scarb2 | scavenger receptor class B, member 2 | 0.089 | ||
| Apoe | apolipoprotein E | 0.083 | Human | |
| Scpep1 | serine carboxypeptidase 1 | 0.081 | ||
| Kiss1 | KiSS-1 metastasis-suppressor | 0.077 | ||
| Atp6ap2 | ATPase, H+ transporting, lysosomal accessory protein 2 | 0.074 | ||
| Fuca1 | fucosidase, alpha-L- 1, tissue | 0.073 | ||
| Itgb5 | integrin beta 5 | 0.073 | ||
| Abcg1 | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.070 | ||
| Shisa5 | shisa homolog 5 (Xenopus laevis) | 0.063 | ||
| Gaa | glucosidase, alpha, acid | 0.061 | ||
| Cst3 | cystatin C | 0.059 | ||
| Lepr | leptin receptor | 0.056 | ||
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.050 | ||
| Npc1 | Niemann Pick type C1 | 0.047 | Human | |
| Nucb1 | nucleobindin 1 | 0.047 | ||
| Gm2a | GM2 ganglioside activator protein | 0.043 | Human | |
| Rnh1 | ribonuclease/angiogenin inhibitor 1 | 0.040 | ||
| Ctsl | cathepsin L | 0.038 | ||
| Kdelr1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.036 | ||
| Pten | phosphatase and tensin homolog | 0.034 | ||
| C1qa | complement component 1, q subcomponent, alpha polypeptide | 0.034 | ||
| Cstb | cystatin B | 0.033 | ||
| Cdipt | CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase) | 0.033 | ||
| Ctsh | cathepsin H | 0.032 | ||
| Myo7a | myosin VIIA | 0.031 | ||
| Anxa5 | annexin A5 | 0.030 | ||
| Hgsnat | heparan-alpha-glucosaminide N-acetyltransferase | 0.029 | ||
| Gpr116 | G protein-coupled receptor 116 | 0.029 | ||
| Lrpap1 | low density lipoprotein receptor-related protein associated protein 1 | 0.029 | ||
| Tyrobp | TYRO protein tyrosine kinase binding protein | 0.029 | ||
| Tmem176b | transmembrane protein 176B | 0.028 | ||
| Aga | aspartylglucosaminidase | 0.028 | ||
| Glb1 | galactosidase, beta 1 | 0.028 | Human | |
| Itm2b | integral membrane protein 2B | 0.028 | ||
| Cndp2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | 0.026 | ||
| Ldlr | low density lipoprotein receptor | 0.026 | ||
| Fcer1g | Fc receptor, IgE, high affinity I, gamma polypeptide | 0.026 | ||
| Klraq1 | KLRAQ motif containing 1 | 0.025 | ||
| Cyba | cytochrome b-245, alpha polypeptide | 0.024 | ||
| Txndc16 | thioredoxin domain containing 16 | 0.024 | ||
| Rab7l1 | RAB7, member RAS oncogene family-like 1 | 0.024 | ||
| Clcn5 | chloride channel 5 | 0.024 | ||
| Creg1 | cellular repressor of E1A-stimulated genes 1 | 0.023 | ||
| Renbp | renin binding protein | 0.023 | ||
| Pltp | phospholipid transfer protein | 0.022 | ||
| C1qc | complement component 1, q subcomponent, C chain | 0.022 | ||
| Csf1r | colony stimulating factor 1 receptor | 0.022 | ||
| Abhd12 | abhydrolase domain containing 12 | 0.022 | ||
| Tmub2 | transmembrane and ubiquitin-like domain containing 2 | 0.021 | ||
| Tmem176a | transmembrane protein 176A | 0.021 | ||
| Irs2 | insulin receptor substrate 2 | 0.021 | ||
| Sgpl1 | sphingosine phosphate lyase 1 | 0.021 | ||
| Cd68 | CD68 antigen | 0.020 | ||
| Lipa | lysosomal acid lipase A | 0.020 | ||
| Glg1 | golgi apparatus protein 1 | 0.020 | ||
| Plin2 | perilipin 2 | 0.020 | ||
| Sat1 | spermidine/spermine N1-acetyl transferase 1 | 0.019 | ||
| Foxo3 | forkhead box O3 | 0.019 | ||
| Ifngr1 | interferon gamma receptor 1 | 0.019 | ||
| Sumf1 | sulfatase modifying factor 1 | 0.019 | Human | |
| Adam9 | a disintegrin and metallopeptidase domain 9 (meltrin gamma) | 0.018 | ||
| P2rx4 | purinergic receptor P2X, ligand-gated ion channel 4 | 0.018 | ||
| Elovl1 | elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 | 0.017 | ||
| Sh3bgrl3 | SH3 domain binding glutamic acid-rich protein-like 3 | 0.017 | ||
| Sepp1 | selenoprotein P, plasma, 1 | 0.017 | ||
| Dicer1 | Dicer1, Dcr-1 homolog (Drosophila) | 0.017 | ||
| Nhlrc3 | NHL repeat containing 3 | 0.017 | ||
| Tm7sf3 | transmembrane 7 superfamily member 3 | 0.017 | ||
| Leprot | leptin receptor overlapping transcript | 0.017 | ||
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.016 | ||
| Ndfip1 | Nedd4 family interacting protein 1 | 0.016 | ||
| Acp2 | acid phosphatase 2, lysosomal | 0.016 | ||
| App | amyloid beta (A4) precursor protein | 0.016 | ||
| Uap1l1 | UDP-N-acteylglucosamine pyrophosphorylase 1-like 1 | 0.016 | ||
| Stx4a | syntaxin 4A (placental) | 0.016 | ||
| Capns1 | calpain, small subunit 1 | 0.015 | ||
| Arsa | arylsulfatase A | 0.015 | ||
| Atp6v0e | ATPase, H+ transporting, lysosomal V0 subunit E | 0.015 | ||
| Apc | adenomatosis polyposis coli | 0.015 | ||
| Pla2g15 | phospholipase A2, group XV | 0.015 | ||
| Aplp2 | amyloid beta (A4) precursor-like protein 2 | 0.015 | ||
| Tmem50a | transmembrane protein 50A | 0.015 | ||
| Tmem111 | transmembrane protein 111 | 0.015 | ||
| Akr1a4 | aldo-keto reductase family 1, member A4 (aldehyde reductase) | 0.015 | ||
| Ostm1 | osteopetrosis associated transmembrane protein 1 | 0.014 | ||
| Mfge8 | milk fat globule-EGF factor 8 protein | 0.014 | ||
| Pcyox1 | prenylcysteine oxidase 1 | 0.014 | ||
| C1qb | complement component 1, q subcomponent, beta polypeptide | 0.014 | ||
| Kif3b | kinesin family member 3B | 0.013 | ||
| Hsd17b11 | hydroxysteroid (17-beta) dehydrogenase 11 | 0.013 | ||
| 2310044H10Rik | RIKEN cDNA 2310044H10 gene | 0.013 | ||
| Tk2 | thymidine kinase 2, mitochondrial | 0.013 | ||
| Tsc1 | tuberous sclerosis 1 | 0.013 | ||
| Clta | clathrin, light polypeptide (Lca) | 0.013 | ||
| Cln5 | ceroid-lipofuscinosis, neuronal 5 | 0.013 | ||
| Atp6v0c | ATPase, H+ transporting, lysosomal V0 subunit C | 0.013 | ||
| D6Wsu116e | DNA segment, Chr 6, Wayne State University 116, expressed | 0.013 | ||
| Dap | death-associated protein | 0.013 | ||
| Ftl1 | ferritin light chain 1 | 0.013 | ||
| Ergic3 | ERGIC and golgi 3 | 0.013 | ||
| Fcgr2b | Fc receptor, IgG, low affinity IIb | 0.012 | ||
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.012 | ||
| Mertk | c-mer proto-oncogene tyrosine kinase | 0.012 | ||
| C3 | complement component 3 | 0.012 | ||
| Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.012 | ||
| Pttg1ip | pituitary tumor-transforming 1 interacting protein | 0.012 | ||
| Ctss | cathepsin S | 0.012 | ||
| Gabarap | gamma-aminobutyric acid receptor associated protein | 0.012 | ||
| Grina | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) | 0.012 | ||
| Braf | Braf transforming gene | 0.012 | ||
| Sdf2 | stromal cell derived factor 2 | 0.011 | ||
| 1110003E01Rik | RIKEN cDNA 1110003E01 gene | 0.011 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.011 | ||
| Yipf3 | Yip1 domain family, member 3 | 0.011 | ||
| Ccpg1 | cell cycle progression 1 | 0.011 | ||
| Tex264 | testis expressed gene 264 | 0.011 | ||
| Rnase4 | ribonuclease, RNase A family 4 | 0.011 | ||
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.011 | ||
| Tmem9b | TMEM9 domain family, member B | 0.011 | ||
| Anxa4 | annexin A4 | 0.011 | ||
| Vkorc1 | vitamin K epoxide reductase complex, subunit 1 | 0.011 | ||
| Fcgrt | Fc receptor, IgG, alpha chain transporter | 0.010 | ||
| Daglb | diacylglycerol lipase, beta | 0.010 | ||
| Nagk | N-acetylglucosamine kinase | 0.010 | ||
| Tmem19 | transmembrane protein 19 | 0.010 | ||
| Cpt1a | carnitine palmitoyltransferase 1a, liver | 0.010 | ||
| Scamp2 | secretory carrier membrane protein 2 | 0.010 | ||
| Rnf103 | ring finger protein 103 | 0.010 |