IMP

Process View

Mus musculus

1 genes annotated in mouse

response to bile acid

GO:1903412

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "response to bile acid"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "response to bile acid" (in gray)

Name	Description	Probability	Func Analog Organism
Lep	leptin	0.988
Lepr	leptin receptor	0.982
Esr1	estrogen receptor 1 (alpha)	0.719
Cav1	caveolin 1, caveolae protein	0.615
Nos3	nitric oxide synthase 3, endothelial cell	0.577
Insr	insulin receptor	0.577
Tgfb1	transforming growth factor, beta 1	0.494
Rxra	retinoid X receptor alpha	0.432
Apoe	apolipoprotein E	0.368
Nos2	nitric oxide synthase 2, inducible	0.334
Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	0.244
Pparg	peroxisome proliferator activated receptor gamma	0.216	Mouse
Nos1	nitric oxide synthase 1, neuronal	0.194
Tlr4	toll-like receptor 4	0.132
Il10	interleukin 10	0.114
Cyp2d26	cytochrome P450, family 2, subfamily d, polypeptide 26	0.111
Slc26a1	solute carrier family 26 (sulfate transporter), member 1	0.106
Hpd	4-hydroxyphenylpyruvic acid dioxygenase	0.099
Csf1	colony stimulating factor 1 (macrophage)	0.097
Hnf4a	hepatic nuclear factor 4, alpha	0.095
Apoa1	apolipoprotein A-I	0.085
Sult1b1	sulfotransferase family 1B, member 1	0.084
Nr1i2	nuclear receptor subfamily 1, group I, member 2	0.080	Mouse
Hr	hairless	0.070
Rdh16	retinol dehydrogenase 16	0.070
Gnas	GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus	0.069
Fas	Fas (TNF receptor superfamily member 6)	0.064
Ghr	growth hormone receptor	0.059
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.057
Gcgr	glucagon receptor	0.052
Agpat2	1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)	0.051
Rab17	RAB17, member RAS oncogene family	0.050
Agt	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.049
Nr1h4	nuclear receptor subfamily 1, group H, member 4	0.048
Phex	phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)	0.047
Apoa4	apolipoprotein A-IV	0.046
Ppargc1a	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha	0.046
Tlr2	toll-like receptor 2	0.045
Ar	androgen receptor	0.044
Nr0b2	nuclear receptor subfamily 0, group B, member 2	0.042
Adipoq	adiponectin, C1Q and collagen domain containing	0.041
Ldlr	low density lipoprotein receptor	0.040
Nr1i3	nuclear receptor subfamily 1, group I, member 3	0.039	Mouse
Baat	bile acid-Coenzyme A: amino acid N-acyltransferase	0.038
Gc	group specific component	0.037
Hgd	homogentisate 1, 2-dioxygenase	0.036
Rab25	RAB25, member RAS oncogene family	0.036
Ptgs2	prostaglandin-endoperoxide synthase 2	0.035
Vav2	vav 2 oncogene	0.035
Fabp1	fatty acid binding protein 1, liver	0.034
Irs2	insulin receptor substrate 2	0.033
Aldob	aldolase B, fructose-bisphosphate	0.032
Col1a1	collagen, type I, alpha 1	0.032
Vegfa	vascular endothelial growth factor A	0.031
Trp53	transformation related protein 53	0.031
Bche	butyrylcholinesterase	0.031
Tnf	tumor necrosis factor	0.030
Apob	apolipoprotein B	0.030
G6pc	glucose-6-phosphatase, catalytic	0.029
Slc12a1	solute carrier family 12, member 1	0.029
Ppara	peroxisome proliferator activated receptor alpha	0.029	Mouse
Aqp7	aquaporin 7	0.029
Lipa	lysosomal acid lipase A	0.029
Esr2	estrogen receptor 2 (beta)	0.028
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.028
Spp1	secreted phosphoprotein 1	0.028
Habp2	hyaluronic acid binding protein 2	0.028
Clrn3	clarin 3	0.028
Rdh7	retinol dehydrogenase 7	0.028
Fam83f	family with sequence similarity 83, member F	0.027
Abcc2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.027
Lyz2	lysozyme 2	0.027
Inhbc	inhibin beta-C	0.027
Ahsg	alpha-2-HS-glycoprotein	0.026
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.026
Mgmt	O-6-methylguanine-DNA methyltransferase	0.026
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.026
Iyd	iodotyrosine deiodinase	0.026
Cyp3a13	cytochrome P450, family 3, subfamily a, polypeptide 13	0.025
Agtr1a	angiotensin II receptor, type 1a	0.025
Egfr	epidermal growth factor receptor	0.025
Miox	myo-inositol oxygenase	0.025
Vdr	vitamin D receptor	0.024	Mouse
Ggnbp1	gametogenetin binding protein 1	0.023
Car5a	carbonic anhydrase 5a, mitochondrial	0.022
Rxrg	retinoid X receptor gamma	0.022
Agrp	agouti related protein	0.022
Cyp2b10	cytochrome P450, family 2, subfamily b, polypeptide 10	0.022
Mocs1	molybdenum cofactor synthesis 1	0.022
Cebpa	CCAAT/enhancer binding protein (C/EBP), alpha	0.022
Asgr2	asialoglycoprotein receptor 2	0.022
Stat3	signal transducer and activator of transcription 3	0.022
Klk1b4	kallikrein 1-related pepidase b4	0.021
Acsm3	acyl-CoA synthetase medium-chain family member 3	0.021
Hamp	hepcidin antimicrobial peptide	0.021
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.021
Bscl2	Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)	0.021
Cyp2a12	cytochrome P450, family 2, subfamily a, polypeptide 12	0.020
Mat1a	methionine adenosyltransferase I, alpha	0.020
Khk	ketohexokinase	0.020
Tnfrsf11a	tumor necrosis factor receptor superfamily, member 11a	0.020
Apoa2	apolipoprotein A-II	0.020
Pdzk1	PDZ domain containing 1	0.019
Mmp9	matrix metallopeptidase 9	0.019
Timd2	T-cell immunoglobulin and mucin domain containing 2	0.019
Foxn1	forkhead box N1	0.019
Gata6	GATA binding protein 6	0.019
Pcx	pyruvate carboxylase	0.018
Plcg1	phospholipase C, gamma 1	0.018
Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	0.018
Nr5a2	nuclear receptor subfamily 5, group A, member 2	0.018
Fbp2	fructose bisphosphatase 2	0.018
Pigr	polymeric immunoglobulin receptor	0.018
Oxsm	3-oxoacyl-ACP synthase, mitochondrial	0.017
Lgals2	lectin, galactose-binding, soluble 2	0.017
Scd1	stearoyl-Coenzyme A desaturase 1	0.016
Otc	ornithine transcarbamylase	0.016
Ggt1	gamma-glutamyltransferase 1	0.016
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.016
Galm	galactose mutarotase	0.016
Cd44	CD44 antigen	0.016
Cyp21a1	cytochrome P450, family 21, subfamily a, polypeptide 1	0.016
C3	complement component 3	0.016
Fabp2	fatty acid binding protein 2, intestinal	0.016
Guca2b	guanylate cyclase activator 2b (retina)	0.016
Slc22a1	solute carrier family 22 (organic cation transporter), member 1	0.016
Cideb	cell death-inducing DNA fragmentation factor, alpha subunit-like effector B	0.015
Lect2	leukocyte cell-derived chemotaxin 2	0.015
Soat2	sterol O-acyltransferase 2	0.015
Cdhr5	cadherin-related family member 5	0.015
Cyp2c50	cytochrome P450, family 2, subfamily c, polypeptide 50	0.015
Slc3a1	solute carrier family 3, member 1	0.015
Fam83g	family with sequence similarity 83, member G	0.015
Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	0.015
Gnmt	glycine N-methyltransferase	0.015
Lpin1	lipin 1	0.015
Cps1	carbamoyl-phosphate synthetase 1	0.014
Mlycd	malonyl-CoA decarboxylase	0.014
Ifng	interferon gamma	0.014
Slc22a18	solute carrier family 22 (organic cation transporter), member 18	0.014
Acpp	acid phosphatase, prostate	0.014
Sult1d1	sulfotransferase family 1D, member 1	0.014
Azgp1	alpha-2-glycoprotein 1, zinc	0.014
1810021B22Rik	RIKEN cDNA 1810021B22 gene	0.014
Sdsl	serine dehydratase-like	0.014
Gata4	GATA binding protein 4	0.014
Hpn	hepsin	0.014
Foxo4	forkhead box O4	0.014
Lrp5	low density lipoprotein receptor-related protein 5	0.014
Elk4	ELK4, member of ETS oncogene family	0.013
Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	0.013
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.013
Cidec	cell death-inducing DFFA-like effector c	0.013
Gjb1	gap junction protein, beta 1	0.013
Sirt1	sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)	0.013
Ncoa3	nuclear receptor coactivator 3	0.013
Cldn2	claudin 2	0.013
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.013
Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	0.013
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.013
Pnpla2	patatin-like phospholipase domain containing 2	0.012
C8g	complement component 8, gamma polypeptide	0.012
Tdo2	tryptophan 2,3-dioxygenase	0.012
Pklr	pyruvate kinase liver and red blood cell	0.012
Itln1	intelectin 1 (galactofuranose binding)	0.012
Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	0.012
P2ry2	purinergic receptor P2Y, G-protein coupled 2	0.012
Tat	tyrosine aminotransferase	0.012
Tert	telomerase reverse transcriptase	0.012
Dvl3	dishevelled 3, dsh homolog (Drosophila)	0.012
Igf1	insulin-like growth factor 1	0.012
Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	0.012
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.012
Cyp4b1	cytochrome P450, family 4, subfamily b, polypeptide 1	0.012
Dmgdh	dimethylglycine dehydrogenase precursor	0.012
Phlda2	pleckstrin homology-like domain, family A, member 2	0.011
Cyp2b9	cytochrome P450, family 2, subfamily b, polypeptide 9	0.011
Klkb1	kallikrein B, plasma 1	0.011
Aadac	arylacetamide deacetylase (esterase)	0.011
F13b	coagulation factor XIII, beta subunit	0.011
Notch2	Notch gene homolog 2 (Drosophila)	0.011
Erbb4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.011
Clcnka	chloride channel Ka	0.011
Prodh2	proline dehydrogenase (oxidase) 2	0.010
Prm2	protamine 2	0.010
Orm2	orosomucoid 2	0.010
Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	0.010
Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	0.010
Mdh1	malate dehydrogenase 1, NAD (soluble)	0.010
Hoxb13	homeobox B13	0.010
Fam83h	family with sequence similarity 83, member H	0.010
Akr1c21	aldo-keto reductase family 1, member C21	0.010