IMP
Process View
negative regulation of transcription from rna polymerase ii promoter in response to stress
Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
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Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of transcription from rna polymerase ii promoter in response to stress"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| Fos | FBJ osteosarcoma oncogene | 0.975 | ||
| Vegfa | vascular endothelial growth factor A | 0.901 | ||
| Dusp1 | dual specificity phosphatase 1 | 0.741 | ||
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.637 | ||
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.601 | ||
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.504 | ||
| Atf3 | activating transcription factor 3 | 0.483 | ||
| Junb | Jun-B oncogene | 0.348 | ||
| Trp53 | transformation related protein 53 | 0.311 | ||
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.279 | ||
| Btg2 | B-cell translocation gene 2, anti-proliferative | 0.275 | ||
| Zfp36 | zinc finger protein 36 | 0.258 | ||
| Egr1 | early growth response 1 | 0.258 | ||
| Jag1 | jagged 1 | 0.240 | ||
| Rhob | ras homolog gene family, member B | 0.228 | ||
| Cdkn1a | cyclin-dependent kinase inhibitor 1A (P21) | 0.204 | ||
| Klf6 | Kruppel-like factor 6 | 0.170 | ||
| Smad3 | MAD homolog 3 (Drosophila) | 0.150 | ||
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.134 | ||
| Rxra | retinoid X receptor alpha | 0.129 | ||
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.125 | ||
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.123 | ||
| Apc | adenomatosis polyposis coli | 0.108 | ||
| Acvr1 | activin A receptor, type 1 | 0.107 | ||
| Fgfr2 | fibroblast growth factor receptor 2 | 0.107 | ||
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.104 | ||
| Stat3 | signal transducer and activator of transcription 3 | 0.097 | ||
| Nr4a1 | nuclear receptor subfamily 4, group A, member 1 | 0.089 | ||
| Cd151 | CD151 antigen | 0.085 | ||
| Rela | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.075 | ||
| Hif1a | hypoxia inducible factor 1, alpha subunit | 0.074 | ||
| Ier3 | immediate early response 3 | 0.073 | ||
| Mapk8 | mitogen-activated protein kinase 8 | 0.066 | ||
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.065 | ||
| Sox9 | SRY-box containing gene 9 | 0.065 | ||
| Ier2 | immediate early response 2 | 0.061 | ||
| Pten | phosphatase and tensin homolog | 0.060 | ||
| Cyr61 | cysteine rich protein 61 | 0.054 | ||
| Bmp4 | bone morphogenetic protein 4 | 0.054 | ||
| Apoe | apolipoprotein E | 0.053 | ||
| Kit | kit oncogene | 0.052 | ||
| Sqstm1 | sequestosome 1 | 0.052 | ||
| Egln1 | EGL nine homolog 1 (C. elegans) | 0.049 | ||
| Ilk | integrin linked kinase | 0.048 | ||
| Lyz2 | lysozyme 2 | 0.047 | ||
| Lepr | leptin receptor | 0.047 | ||
| Epas1 | endothelial PAS domain protein 1 | 0.039 | ||
| Cebpb | CCAAT/enhancer binding protein (C/EBP), beta | 0.039 | ||
| Kras | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.038 | ||
| Prkci | protein kinase C, iota | 0.036 | ||
| Klf4 | Kruppel-like factor 4 (gut) | 0.036 | ||
| Mgrn1 | mahogunin, ring finger 1 | 0.035 | ||
| Nfil3 | nuclear factor, interleukin 3, regulated | 0.034 | ||
| Pparg | peroxisome proliferator activated receptor gamma | 0.033 | ||
| Pkd1 | polycystic kidney disease 1 homolog | 0.033 | ||
| Hprt | hypoxanthine guanine phosphoribosyl transferase | 0.030 | ||
| Atf4 | activating transcription factor 4 | 0.029 | ||
| Lama5 | laminin, alpha 5 | 0.029 | ||
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.028 | ||
| Jun | Jun oncogene | 0.027 | Human | |
| Thbs1 | thrombospondin 1 | 0.025 | ||
| Rabac1 | Rab acceptor 1 (prenylated) | 0.024 | ||
| Foxc1 | forkhead box C1 | 0.022 | ||
| Tgfb2 | transforming growth factor, beta 2 | 0.022 | ||
| Napa | N-ethylmaleimide sensitive fusion protein attachment protein alpha | 0.022 | ||
| Gabarap | gamma-aminobutyric acid receptor associated protein | 0.021 | ||
| Efnb2 | ephrin B2 | 0.021 | ||
| Mafk | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) | 0.021 | ||
| Fgfr1 | fibroblast growth factor receptor 1 | 0.021 | ||
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.020 | ||
| Fas | Fas (TNF receptor superfamily member 6) | 0.019 | ||
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.019 | ||
| Lmna | lamin A | 0.019 | ||
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.019 | ||
| Gadd45b | growth arrest and DNA-damage-inducible 45 beta | 0.018 | ||
| Psen1 | presenilin 1 | 0.018 | ||
| Tex264 | testis expressed gene 264 | 0.017 | ||
| Rarb | retinoic acid receptor, beta | 0.017 | ||
| Megf8 | multiple EGF-like-domains 8 | 0.017 | ||
| Nfkbia | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.016 | ||
| Mdm2 | transformed mouse 3T3 cell double minute 2 | 0.016 | ||
| Kitl | kit ligand | 0.016 | ||
| Smad4 | MAD homolog 4 (Drosophila) | 0.016 | ||
| Maff | v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) | 0.015 | ||
| Sertad1 | SERTA domain containing 1 | 0.015 | ||
| 4933426M11Rik | RIKEN cDNA 4933426M11 gene | 0.015 | ||
| Kif3a | kinesin family member 3A | 0.015 | ||
| Irs2 | insulin receptor substrate 2 | 0.014 | ||
| Ets2 | E26 avian leukemia oncogene 2, 3' domain | 0.014 | ||
| Capns1 | calpain, small subunit 1 | 0.014 | ||
| Nf1 | neurofibromatosis 1 | 0.014 | ||
| Errfi1 | ERBB receptor feedback inhibitor 1 | 0.014 | ||
| Csrnp1 | cysteine-serine-rich nuclear protein 1 | 0.014 | ||
| Pkd2 | polycystic kidney disease 2 | 0.013 | ||
| Kif3b | kinesin family member 3B | 0.013 | ||
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.013 | ||
| Egr2 | early growth response 2 | 0.013 | ||
| Wbp2 | WW domain binding protein 2 | 0.012 | ||
| Ppp1r15a | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.012 | ||
| Bhlhe40 | basic helix-loop-helix family, member e40 | 0.012 | ||
| Per1 | period homolog 1 (Drosophila) | 0.012 | ||
| Gadd45g | growth arrest and DNA-damage-inducible 45 gamma | 0.012 | ||
| Stk11 | serine/threonine kinase 11 | 0.012 | ||
| Egfr | epidermal growth factor receptor | 0.012 | ||
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.012 | ||
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.011 | ||
| Slc3a2 | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 0.011 | ||
| Nfe2l2 | nuclear factor, erythroid derived 2, like 2 | 0.011 | ||
| Atg13 | ATG13 autophagy related 13 homolog (S. cerevisiae) | 0.011 | ||
| Rara | retinoic acid receptor, alpha | 0.010 | ||
| Nr1h2 | nuclear receptor subfamily 1, group H, member 2 | 0.010 | ||
| Foxc2 | forkhead box C2 | 0.010 | ||
| Ubap1 | ubiquitin-associated protein 1 | 0.010 | ||
| Cav1 | caveolin 1, caveolae protein | 0.010 |