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Process View

Mus musculus

6 genes annotated in mouse

diencephalon morphogenesis

The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "diencephalon morphogenesis"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "diencephalon morphogenesis" (in gray)

Name	Description	Probability	Func Analog Organism
Shh	sonic hedgehog	1.000
Gli3	GLI-Kruppel family member GLI3	1.000
Pax2	paired box gene 2	1.000
Fgf8	fibroblast growth factor 8	1.000
Fgfr2	fibroblast growth factor receptor 2	1.000
Pax3	paired box gene 3	0.998
Otx2	orthodenticle homolog 2 (Drosophila)	0.990
Foxc1	forkhead box C1	0.989
Msx1	homeobox, msh-like 1	0.988
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.986
Gli2	GLI-Kruppel family member GLI2	0.986	Zebrafish
Pitx2	paired-like homeodomain transcription factor 2	0.982
Bmp4	bone morphogenetic protein 4	0.973
Rarg	retinoic acid receptor, gamma	0.967
Sox9	SRY-box containing gene 9	0.965	Mouse
Hand1	heart and neural crest derivatives expressed transcript 1	0.952
Smo	smoothened homolog (Drosophila)	0.950
Wnt3a	wingless-related MMTV integration site 3A	0.948	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.943
Fgf10	fibroblast growth factor 10	0.942
Pax8	paired box gene 8	0.939
Tcfap2a	transcription factor AP-2, alpha	0.931
Tbx1	T-box 1	0.906
Lhx1	LIM homeobox protein 1	0.885
Bmp7	bone morphogenetic protein 7	0.882
Pax6	paired box gene 6	0.882
Foxc2	forkhead box C2	0.860
Lmx1b	LIM homeobox transcription factor 1 beta	0.839
Isl1	ISL1 transcription factor, LIM/homeodomain	0.839
Prrx1	paired related homeobox 1	0.834
Hand2	heart and neural crest derivatives expressed transcript 2	0.806
Eya1	eyes absent 1 homolog (Drosophila)	0.805
Emx2	empty spiracles homolog 2 (Drosophila)	0.799
Rarb	retinoic acid receptor, beta	0.774
Nog	noggin	0.753
Alx4	aristaless-like homeobox 4	0.744
Gbx2	gastrulation brain homeobox 2	0.725
Otx1	orthodenticle homolog 1 (Drosophila)	0.718
Prrx2	paired related homeobox 2	0.686
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.678
Tgfb2	transforming growth factor, beta 2	0.670
Dlx5	distal-less homeobox 5	0.647
Msx2	homeobox, msh-like 2	0.621
Gdnf	glial cell line derived neurotrophic factor	0.561
Lmx1a	LIM homeobox transcription factor 1 alpha	0.532
Meox2	mesenchyme homeobox 2	0.485
Lhx3	LIM homeobox protein 3	0.477
Tpo	thyroid peroxidase	0.471
Ret	ret proto-oncogene	0.465
Hoxa1	homeobox A1	0.461
Twist2	twist homolog 2 (Drosophila)	0.444
Emx1	empty spiracles homolog 1 (Drosophila)	0.436
Sox2	SRY-box containing gene 2	0.436
Nodal	nodal	0.434
Ctnnb1	catenin (cadherin associated protein), beta 1	0.415
Col2a1	collagen, type II, alpha 1	0.390
Chrd	chordin	0.361
Fgfr3	fibroblast growth factor receptor 3	0.351
Hoxa2	homeobox A2	0.347
Hoxd13	homeobox D13	0.290
Rara	retinoic acid receptor, alpha	0.289
Fgf3	fibroblast growth factor 3	0.278
Ednra	endothelin receptor type A	0.259
Pdgfra	platelet derived growth factor receptor, alpha polypeptide	0.254
En1	engrailed 1	0.248
Tbx2	T-box 2	0.214
Chd7	chromodomain helicase DNA binding protein 7	0.203
Alx3	aristaless-like homeobox 3	0.203
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.194
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.194
Wnt6	wingless-related MMTV integration site 6	0.189	Mouse
Zeb1	zinc finger E-box binding homeobox 1	0.178
Hes1	hairy and enhancer of split 1 (Drosophila)	0.176
Gsc	goosecoid homeobox	0.175
Hoxd11	homeobox D11	0.174
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.161
Pou3f3	POU domain, class 3, transcription factor 3	0.152
Aldh1a2	aldehyde dehydrogenase family 1, subfamily A2	0.143
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.143
Col13a1	collagen, type XIII, alpha 1	0.134
Tcfap2c	transcription factor AP-2, gamma	0.128
Hoxa3	homeobox A3	0.124
Efnb2	ephrin B2	0.123
T	brachyury	0.121
Pitx1	paired-like homeodomain transcription factor 1	0.120
Foxg1	forkhead box G1	0.118
Gata4	GATA binding protein 4	0.118
Pou3f1	POU domain, class 3, transcription factor 1	0.116
Hoxa13	homeobox A13	0.116
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.115
Ntf3	neurotrophin 3	0.115
Lef1	lymphoid enhancer binding factor 1	0.114
Emid2	EMI domain containing 2	0.111
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.100
Hoxa11	homeobox A11	0.093
Btbd17	BTB (POZ) domain containing 17	0.092
Rspo2	R-spondin 2 homolog (Xenopus laevis)	0.091
Wnt4	wingless-related MMTV integration site 4	0.090	Mouse
Tbx15	T-box 15	0.089
Ptch1	patched homolog 1	0.086
Jag1	jagged 1	0.082
Vangl2	vang-like 2 (van gogh, Drosophila)	0.081
Foxd2	forkhead box D2	0.077
Tbx3	T-box 3	0.077
Sall3	sal-like 3 (Drosophila)	0.075
Hes5	hairy and enhancer of split 5 (Drosophila)	0.072
Hmx3	H6 homeobox 3	0.072
Cdx1	caudal type homeobox 1	0.071
Sox11	SRY-box containing gene 11	0.070	Mouse
Mesp1	mesoderm posterior 1	0.064
Lhx5	LIM homeobox protein 5	0.064
Foxf1a	forkhead box F1a	0.063
Pax9	paired box gene 9	0.063
Pax1	paired box gene 1	0.062
Rxra	retinoid X receptor alpha	0.060
Vegfa	vascular endothelial growth factor A	0.060
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.058
Wnt1	wingless-related MMTV integration site 1	0.056	Mouse
Ephb2	Eph receptor B2	0.055
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.055
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.054
Fgf15	fibroblast growth factor 15	0.054
Gas1	growth arrest specific 1	0.053
Kl	klotho	0.053
Hoxc5	homeobox C5	0.051
Smad6	MAD homolog 6 (Drosophila)	0.050
Tulp1	tubby like protein 1	0.050
Hspg2	perlecan (heparan sulfate proteoglycan 2)	0.050
Sox7	SRY-box containing gene 7	0.050	Mouse
Vax1	ventral anterior homeobox containing gene 1	0.048
Col22a1	collagen, type XXII, alpha 1	0.047
Fgf5	fibroblast growth factor 5	0.047
Wt1	Wilms tumor 1 homolog	0.046
Pbx1	pre B-cell leukemia transcription factor 1	0.046
Sox3	SRY-box containing gene 3	0.044	Mouse
Fzd10	frizzled homolog 10 (Drosophila)	0.043
Dlx1	distal-less homeobox 1	0.043
Foxh1	forkhead box H1	0.042
Pitx3	paired-like homeodomain transcription factor 3	0.042
Nos3	nitric oxide synthase 3, endothelial cell	0.042
Fgf18	fibroblast growth factor 18	0.040
Gpr50	G-protein-coupled receptor 50	0.040
Gata3	GATA binding protein 3	0.040
Bmper	BMP-binding endothelial regulator	0.039
Uncx	UNC homeobox	0.038
Foxn1	forkhead box N1	0.038
She	src homology 2 domain-containing transforming protein E	0.036
Tcf15	transcription factor 15	0.036
Efna2	ephrin A2	0.035
Hoxa4	homeobox A4	0.035
Tcf21	transcription factor 21	0.035
Onecut1	one cut domain, family member 1	0.034
Prop1	paired like homeodomain factor 1	0.034
Drd2	dopamine receptor D2	0.034
Neurog1	neurogenin 1	0.033
Zic2	zinc finger protein of the cerebellum 2	0.033
Fgf17	fibroblast growth factor 17	0.033
Fgf4	fibroblast growth factor 4	0.030
Efna4	ephrin A4	0.030
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.029
Barx2	BarH-like homeobox 2	0.029
Hoxb13	homeobox B13	0.028
En2	engrailed 2	0.028
Cldn5	claudin 5	0.028
Hes3	hairy and enhancer of split 3 (Drosophila)	0.028
Trp63	transformation related protein 63	0.027
Wnt11	wingless-related MMTV integration site 11	0.027	Mouse
Acan	aggrecan	0.027
Pou3f4	POU domain, class 3, transcription factor 4	0.027
Hoxa10	homeobox A10	0.026
Hoxd3	homeobox D3	0.026
Gdf11	growth differentiation factor 11	0.025
Lhx9	LIM homeobox protein 9	0.025
Kcnh3	potassium voltage-gated channel, subfamily H (eag-related), member 3	0.024
Npas1	neuronal PAS domain protein 1	0.024
Wnt10b	wingless related MMTV integration site 10b	0.024	Mouse
Snai1	snail homolog 1 (Drosophila)	0.024
Bmp2	bone morphogenetic protein 2	0.024
BC024139	cDNA sequence BC024139	0.023
Aplnr	apelin receptor	0.023
Vstm2b	V-set and transmembrane domain containing 2B	0.023
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.023
Sox1	SRY-box containing gene 1	0.023
Adra2b	adrenergic receptor, alpha 2b	0.023
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.023
Cilp2	cartilage intermediate layer protein 2	0.023
Acvr1	activin A receptor, type 1	0.023
Gata6	GATA binding protein 6	0.023
Dlx6	distal-less homeobox 6	0.022
Nkx2-1	NK2 homeobox 1	0.022
Tbx10	T-box 10	0.022
Foxl2	forkhead box L2	0.022
Fzd4	frizzled homolog 4 (Drosophila)	0.021
Nrtn	neurturin	0.021
Wnt7a	wingless-related MMTV integration site 7A	0.021	Mouse
Atoh7	atonal homolog 7 (Drosophila)	0.021
Foxf2	forkhead box F2	0.021
Wnt9b	wingless-type MMTV integration site 9B	0.020	Mouse
Hoxb3	homeobox B3	0.020
Irx4	Iroquois related homeobox 4 (Drosophila)	0.020
Bnc1	basonuclin 1	0.020
Ptch2	patched homolog 2	0.020
Zic1	zinc finger protein of the cerebellum 1	0.019
Lama5	laminin, alpha 5	0.019
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.019
Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	0.019
Theg	testicular haploid expressed gene	0.019
Pou4f2	POU domain, class 4, transcription factor 2	0.019
Pou5f1	POU domain, class 5, transcription factor 1	0.019
Hoxc6	homeobox C6	0.019
Hoxa5	homeobox A5	0.018
Eda	ectodysplasin-A	0.018
Ptprb	protein tyrosine phosphatase, receptor type, B	0.018
Cldn6	claudin 6	0.018
Hmx1	H6 homeobox 1	0.018
Wnt3	wingless-related MMTV integration site 3	0.018	Mouse
Lrp6	low density lipoprotein receptor-related protein 6	0.018
Phox2b	paired-like homeobox 2b	0.018
Nkx6-1	NK6 homeobox 1	0.017
Zfp503	zinc finger protein 503	0.017
Zfp703	zinc finger protein 703	0.017
Notch3	Notch gene homolog 3 (Drosophila)	0.017
Gja3	gap junction protein, alpha 3	0.017
Fzd2	frizzled homolog 2 (Drosophila)	0.016
Efs	embryonal Fyn-associated substrate	0.016
Wnt9a	wingless-type MMTV integration site 9A	0.016	Mouse
Foxb1	forkhead box B1	0.016
Pax7	paired box gene 7	0.016
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.016
Nkx2-6	NK2 transcription factor related, locus 6 (Drosophila)	0.016
Arx	aristaless related homeobox	0.016
Phox2a	paired-like homeobox 2a	0.016
Rspo1	R-spondin homolog (Xenopus laevis)	0.016
Neurog3	neurogenin 3	0.016
Gpc3	glypican 3	0.015
Col11a1	collagen, type XI, alpha 1	0.015
Dmbx1	diencephalon/mesencephalon homeobox 1	0.015
Ptk7	PTK7 protein tyrosine kinase 7	0.015
Foxd1	forkhead box D1	0.015
Twist1	twist homolog 1 (Drosophila)	0.015
Tshr	thyroid stimulating hormone receptor	0.015
Ptpn11	protein tyrosine phosphatase, non-receptor type 11	0.014
Sim2	single-minded homolog 2 (Drosophila)	0.014
Zic3	zinc finger protein of the cerebellum 3	0.014
Alx1	ALX homeobox 1	0.014
Hesx1	homeobox gene expressed in ES cells	0.014
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.014
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.014
Cnga3	cyclic nucleotide gated channel alpha 3	0.014
Pthlh	parathyroid hormone-like peptide	0.014
Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.014
Krt17	keratin 17	0.013
Gli1	GLI-Kruppel family member GLI1	0.013	Zebrafish
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.013
Hoxc4	homeobox C4	0.013
Mmp24	matrix metallopeptidase 24	0.013
Nf1	neurofibromatosis 1	0.013
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.013
Fzd8	frizzled homolog 8 (Drosophila)	0.013
Tead3	TEA domain family member 3	0.013
Barx1	BarH-like homeobox 1	0.013
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.013
Hoxb6	homeobox B6	0.013
Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	0.013
Insm1	insulinoma-associated 1	0.013
Hoxd9	homeobox D9	0.013
Sox10	SRY-box containing gene 10	0.012	Mouse
Sema5b	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	0.012
Pcdh12	protocadherin 12	0.012
Adra2a	adrenergic receptor, alpha 2a	0.012
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.012
Ihh	Indian hedgehog	0.012
Msi1	Musashi homolog 1(Drosophila)	0.012
Dlx4	distal-less homeobox 4	0.012
Wnt5a	wingless-related MMTV integration site 5A	0.012
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.012
Il11	interleukin 11	0.012
Runx2	runt related transcription factor 2	0.011
Fbn2	fibrillin 2	0.011
Dmrt3	doublesex and mab-3 related transcription factor 3	0.011
Tal2	T-cell acute lymphocytic leukemia 2	0.011
Lhx6	LIM homeobox protein 6	0.011
Hoxd12	homeobox D12	0.011
Bhlhe23	basic helix-loop-helix family, member e23	0.011
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.011
Obsl1	obscurin-like 1	0.011
Dlx2	distal-less homeobox 2	0.011
Thrb	thyroid hormone receptor beta	0.011
Olfr70	olfactory receptor 70	0.011
Bdnf	brain derived neurotrophic factor	0.011
Edar	ectodysplasin-A receptor	0.011
Cbln1	cerebellin 1 precursor protein	0.011
Sall4	sal-like 4 (Drosophila)	0.011
Krt15	keratin 15	0.011
Pou3f2	POU domain, class 3, transcription factor 2	0.010
Ednrb	endothelin receptor type B	0.010
Rbpjl	recombination signal binding protein for immunoglobulin kappa J region-like	0.010
Pou4f3	POU domain, class 4, transcription factor 3	0.010
Hoxb2	homeobox B2	0.010
C1ql1	complement component 1, q subcomponent-like 1	0.010
Crlf1	cytokine receptor-like factor 1	0.010
Msx3	homeobox, msh-like 3	0.010
Matn4	matrilin 4	0.010
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.010