IMP

Process View

Mus musculus

17 genes annotated in mouse

regulation of mitochondrial membrane permeability

Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of mitochondrial membrane permeability"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "regulation of mitochondrial membrane permeability" (in gray)

Name	Description	Probability	Func Analog Organism
Bax	BCL2-associated X protein	0.998
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.988
Bcl2	B-cell leukemia/lymphoma 2	0.857
Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	0.805
Apc	adenomatosis polyposis coli	0.732
Mcl1	myeloid cell leukemia sequence 1	0.611	Mouse
Trp53	transformation related protein 53	0.557
Pdcd6ip	programmed cell death 6 interacting protein	0.498
Pten	phosphatase and tensin homolog	0.473
Bcl2l1	BCL2-like 1	0.439	Human Mouse
Grin1	glutamate receptor, ionotropic, NMDA1 (zeta 1)	0.434
Kit	kit oncogene	0.295
Dlg4	discs, large homolog 4 (Drosophila)	0.283
Smad3	MAD homolog 3 (Drosophila)	0.271
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.257
Axin1	axin 1	0.252
Ctnnb1	catenin (cadherin associated protein), beta 1	0.210
Grin2b	glutamate receptor, ionotropic, NMDA2B (epsilon 2)	0.174
Dnm1	dynamin 1	0.174
Sharpin	SHANK-associated RH domain interacting protein	0.162
Vhl	von Hippel-Lindau tumor suppressor	0.159
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.153
Bak1	BCL2-antagonist/killer 1	0.144	Mouse
Mtap2	microtubule-associated protein 2	0.109
Atp5b	ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit	0.105
Btrc	beta-transducin repeat containing protein	0.098
Mta1	metastasis associated 1	0.094
Dctpp1	dCTP pyrophosphatase 1	0.093
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.088
Atxn2	ataxin 2	0.066
Mapk1	mitogen-activated protein kinase 1	0.065
Mlf2	myeloid leukemia factor 2	0.063
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.061
Mapk8	mitogen-activated protein kinase 8	0.060
Arc	activity regulated cytoskeletal-associated protein	0.058
Akt1	thymoma viral proto-oncogene 1	0.053
Homer1	homer homolog 1 (Drosophila)	0.053
Rock2	Rho-associated coiled-coil containing protein kinase 2	0.051
Actn2	actinin alpha 2	0.049
Btbd2	BTB (POZ) domain containing 2	0.045
Rab1b	RAB1B, member RAS oncogene family	0.045
Stim2	stromal interaction molecule 2	0.041
Prkdc	protein kinase, DNA activated, catalytic polypeptide	0.039
Camk2b	calcium/calmodulin-dependent protein kinase II, beta	0.037	Mouse
Ccnd1	cyclin D1	0.035
Igh	immunoglobulin heavy chain complex	0.033
Tnfaip3	tumor necrosis factor, alpha-induced protein 3	0.032
Bbc3	BCL2 binding component 3	0.031
Bhlhe40	basic helix-loop-helix family, member e40	0.031
Prkci	protein kinase C, iota	0.030
Casp3	caspase 3	0.030
Grm1	glutamate receptor, metabotropic 1	0.030
Rbck1	RanBP-type and C3HC4-type zinc finger containing 1	0.029
Foxp3	forkhead box P3	0.028
Dlg2	discs, large homolog 2 (Drosophila)	0.028
Emx1	empty spiracles homolog 1 (Drosophila)	0.027
Skil	SKI-like	0.027
Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)	0.027
Mdm2	transformed mouse 3T3 cell double minute 2	0.027
Gstz1	glutathione transferase zeta 1 (maleylacetoacetate isomerase)	0.026
Mapk14	mitogen-activated protein kinase 14	0.026
Snap25	synaptosomal-associated protein 25	0.025
Acd	adrenocortical dysplasia	0.025
Rara	retinoic acid receptor, alpha	0.025
Prkaca	protein kinase, cAMP dependent, catalytic, alpha	0.024
Mfn2	mitofusin 2	0.024
Flii	flightless I homolog (Drosophila)	0.024
Smarcd1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.023
Gapdh	glyceraldehyde-3-phosphate dehydrogenase	0.022
Rfc2	replication factor C (activator 1) 2	0.022
Lef1	lymphoid enhancer binding factor 1	0.021
Pik3r2	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta)	0.021
Syn1	synapsin I	0.021
Ptgs2	prostaglandin-endoperoxide synthase 2	0.019
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.019
Ikzf1	IKAROS family zinc finger 1	0.019
Socs3	suppressor of cytokine signaling 3	0.018
Dlgap1	discs, large (Drosophila) homolog-associated protein 1	0.018
Sox2	SRY-box containing gene 2	0.018
Nf2	neurofibromatosis 2	0.017
Epn1	epsin 1	0.016
Pmm1	phosphomannomutase 1	0.016
Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1	0.016
Mta2	metastasis-associated gene family, member 2	0.016
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.015
Dicer1	Dicer1, Dcr-1 homolog (Drosophila)	0.015
Ar	androgen receptor	0.015
Ilk	integrin linked kinase	0.015
Emx2	empty spiracles homolog 2 (Drosophila)	0.015
Gria2	glutamate receptor, ionotropic, AMPA2 (alpha 2)	0.015
Daxx	Fas death domain-associated protein	0.015
Esr1	estrogen receptor 1 (alpha)	0.015
Acadm	acyl-Coenzyme A dehydrogenase, medium chain	0.015
2700094K13Rik	RIKEN cDNA 2700094K13 gene	0.015
Pgam1	phosphoglycerate mutase 1	0.014
Dsg1a	desmoglein 1 alpha	0.014
Cdk4	cyclin-dependent kinase 4	0.014
Mapk3	mitogen-activated protein kinase 3	0.014
Psen1	presenilin 1	0.014
Ncoa3	nuclear receptor coactivator 3	0.014
Ep300	E1A binding protein p300	0.014
Mapk9	mitogen-activated protein kinase 9	0.014
Maff	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)	0.014
Gna11	guanine nucleotide binding protein, alpha 11	0.014
Dlx2	distal-less homeobox 2	0.013
Pfn2	profilin 2	0.013
Pbx1	pre B-cell leukemia transcription factor 1	0.013
Rest	RE1-silencing transcription factor	0.013
Rxra	retinoid X receptor alpha	0.013
Hmbs	hydroxymethylbilane synthase	0.013
Huwe1	HECT, UBA and WWE domain containing 1	0.013
Fos	FBJ osteosarcoma oncogene	0.013
Dusp4	dual specificity phosphatase 4	0.013
Galk1	galactokinase 1	0.013
Cit	citron	0.013
Rps27l	ribosomal protein S27-like	0.013
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.013
Mapk11	mitogen-activated protein kinase 11	0.013
Ryr1	ryanodine receptor 1, skeletal muscle	0.012
Pik3r1	phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)	0.012
Trpc2	transient receptor potential cation channel, subfamily C, member 2	0.012
Actn3	actinin alpha 3	0.012
Echs1	enoyl Coenzyme A hydratase, short chain, 1, mitochondrial	0.012
1110008F13Rik	RIKEN cDNA 1110008F13 gene	0.012
C1qbp	complement component 1, q subcomponent binding protein	0.012
Klc2	kinesin light chain 2	0.012
Cebpb	CCAAT/enhancer binding protein (C/EBP), beta	0.012
Ern1	endoplasmic reticulum (ER) to nucleus signalling 1	0.011
Mrpl10	mitochondrial ribosomal protein L10	0.011
Ywhab	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.011
Hmg20b	high mobility group 20 B	0.011
Gsk3b	glycogen synthase kinase 3 beta	0.011
Neurl1a	neuralized homolog 1A (Drosophila)	0.011
Cobra1	cofactor of BRCA1	0.011
Mdm4	transformed mouse 3T3 cell double minute 4	0.011
Ikzf3	IKAROS family zinc finger 3	0.011
Snrpg	small nuclear ribonucleoprotein polypeptide G	0.011
Cd44	CD44 antigen	0.011
Hist1h1c	histone cluster 1, H1c	0.011
Gsto1	glutathione S-transferase omega 1	0.011
Nefl	neurofilament, light polypeptide	0.010
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.010
Bcl2a1a	B-cell leukemia/lymphoma 2 related protein A1a	0.010	Mouse
Egr1	early growth response 1	0.010
Mccc2	methylcrotonoyl-Coenzyme A carboxylase 2 (beta)	0.010
Pgk1	phosphoglycerate kinase 1	0.010