IMP

Process View

Mus musculus

2 genes annotated in mouse

intestinal epithelial cell maturation

The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "intestinal epithelial cell maturation"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "intestinal epithelial cell maturation" (in gray)

Name	Description	Probability	Func Analog Organism
Hoxb5	homeobox B5	1.000	Mouse
Hoxa5	homeobox A5	0.999
Hoxc5	homeobox C5	0.999	Mouse
Hoxb6	homeobox B6	0.998	Mouse
Hoxb3	homeobox B3	0.998
Hoxd3	homeobox D3	0.998
Hoxc4	homeobox C4	0.994	Mouse
Hoxd9	homeobox D9	0.985
Hoxa9	homeobox A9	0.982
Hoxa10	homeobox A10	0.979
Hoxa2	homeobox A2	0.978
Hoxc8	homeobox C8	0.976	Mouse
Hoxb4	homeobox B4	0.967	Mouse
Hoxc6	homeobox C6	0.960	Mouse
Hoxb9	homeobox B9	0.914
Hoxa11	homeobox A11	0.871
Hoxd10	homeobox D10	0.867
Hoxa4	homeobox A4	0.865	Mouse
Hoxd8	homeobox D8	0.845	Mouse
Hoxb8	homeobox B8	0.819	Mouse
Hoxa3	homeobox A3	0.808
Pbx1	pre B-cell leukemia transcription factor 1	0.800
Hoxc9	homeobox C9	0.747
Hoxb2	homeobox B2	0.731
Hoxa1	homeobox A1	0.730
Wt1	Wilms tumor 1 homolog	0.709
Hoxd4	homeobox D4	0.699	Mouse
Hoxa7	homeobox A7	0.684	Mouse
Gdnf	glial cell line derived neurotrophic factor	0.647
Pax8	paired box gene 8	0.495
Hoxd11	homeobox D11	0.447
Bnc1	basonuclin 1	0.403
Foxd2	forkhead box D2	0.395
Tcfap2a	transcription factor AP-2, alpha	0.376
Twist2	twist homolog 2 (Drosophila)	0.372
Fgfr2	fibroblast growth factor receptor 2	0.342
Sim1	single-minded homolog 1 (Drosophila)	0.340	Mouse
Shh	sonic hedgehog	0.326
Ebf3	early B-cell factor 3	0.274
Sim2	single-minded homolog 2 (Drosophila)	0.246	Mouse
Emid2	EMI domain containing 2	0.245
Dkk2	dickkopf homolog 2 (Xenopus laevis)	0.243
Sox7	SRY-box containing gene 7	0.234
Hoxb1	homeobox B1	0.215
Kras	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.214
Meis1	Meis homeobox 1	0.205
Ihh	Indian hedgehog	0.203
Myod1	myogenic differentiation 1	0.190
Sall3	sal-like 3 (Drosophila)	0.182
Lhx1	LIM homeobox protein 1	0.181
Gpr50	G-protein-coupled receptor 50	0.180
Gli3	GLI-Kruppel family member GLI3	0.171
Dlk1	delta-like 1 homolog (Drosophila)	0.170
Clcnka	chloride channel Ka	0.169
Zfp503	zinc finger protein 503	0.166
Hoxd1	homeobox D1	0.164
Wnt6	wingless-related MMTV integration site 6	0.159
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.145
Pcsk5	proprotein convertase subtilisin/kexin type 5	0.137
Foxd1	forkhead box D1	0.134
Nr3c1	nuclear receptor subfamily 3, group C, member 1	0.133
Hoxb7	homeobox B7	0.129	Mouse
Efna2	ephrin A2	0.128
Foxa2	forkhead box A2	0.125
Hand1	heart and neural crest derivatives expressed transcript 1	0.122
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.121
Nynrin	NYN domain and retroviral integrase containing	0.118
Tbx15	T-box 15	0.114
Cdh16	cadherin 16	0.114
Msx1	homeobox, msh-like 1	0.109
Egln1	EGL nine homolog 1 (C. elegans)	0.105
Myog	myogenin	0.098
Ank1	ankyrin 1, erythroid	0.096
Gata2	GATA binding protein 2	0.092
Tcfap2c	transcription factor AP-2, gamma	0.090
Tcf15	transcription factor 15	0.081
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.078
Glra1	glycine receptor, alpha 1 subunit	0.077
Adra2b	adrenergic receptor, alpha 2b	0.077
Uncx	UNC homeobox	0.077
Pitx2	paired-like homeodomain transcription factor 2	0.077
Hoxc10	homeobox C10	0.077
Shox2	short stature homeobox 2	0.076
Vhl	von Hippel-Lindau tumor suppressor	0.069
Six4	sine oculis-related homeobox 4 homolog (Drosophila)	0.066
Pitx1	paired-like homeodomain transcription factor 1	0.063
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.061
Lhcgr	luteinizing hormone/choriogonadotropin receptor	0.060
Slc34a1	solute carrier family 34 (sodium phosphate), member 1	0.059
Col4a3	collagen, type IV, alpha 3	0.059
En1	engrailed 1	0.058
Tead3	TEA domain family member 3	0.058
Tbx2	T-box 2	0.056
Hand2	heart and neural crest derivatives expressed transcript 2	0.056
Pax2	paired box gene 2	0.054
Lhx9	LIM homeobox protein 9	0.054
Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	0.054
Rdh10	retinol dehydrogenase 10 (all-trans)	0.053
Prph	peripherin	0.052
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.051
Hoxa13	homeobox A13	0.050
Wnt1	wingless-related MMTV integration site 1	0.047
Tbx1	T-box 1	0.046
Fgf4	fibroblast growth factor 4	0.046
Sall4	sal-like 4 (Drosophila)	0.045
Ctf1	cardiotrophin 1	0.044
Otp	orthopedia homolog (Drosophila)	0.044
Lrp2	low density lipoprotein receptor-related protein 2	0.043
Ar	androgen receptor	0.043
Cyp24a1	cytochrome P450, family 24, subfamily a, polypeptide 1	0.043
Nhlh1	nescient helix loop helix 1	0.043
Neurog1	neurogenin 1	0.042
Plac1	placental specific protein 1	0.041
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.041
Slc12a1	solute carrier family 12, member 1	0.041
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.041
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.040
Zfp185	zinc finger protein 185	0.040
Fgf8	fibroblast growth factor 8	0.039
Tcf21	transcription factor 21	0.038
Myoz1	myozenin 1	0.038
Meis2	Meis homeobox 2	0.038
Pax1	paired box gene 1	0.037
Edn3	endothelin 3	0.036
She	src homology 2 domain-containing transforming protein E	0.035
Inca1	inhibitor of CDK, cyclin A1 interacting protein 1	0.035
Tlx3	T-cell leukemia, homeobox 3	0.035
Cldn8	claudin 8	0.034
Vegfa	vascular endothelial growth factor A	0.034
Sox3	SRY-box containing gene 3	0.034
Tbx3	T-box 3	0.034
Stc2	stanniocalcin 2	0.033
Wnt10b	wingless related MMTV integration site 10b	0.032
Wnt2b	wingless related MMTV integration site 2b	0.032
Sult5a1	sulfotransferase family 5A, member 1	0.032
Alx3	aristaless-like homeobox 3	0.032
Pten	phosphatase and tensin homolog	0.031
Efna4	ephrin A4	0.031
Rarb	retinoic acid receptor, beta	0.031
Dhh	desert hedgehog	0.031
Hprt	hypoxanthine guanine phosphoribosyl transferase	0.030
Gata5	GATA binding protein 5	0.030
Wnt11	wingless-related MMTV integration site 11	0.030
C1qtnf3	C1q and tumor necrosis factor related protein 3	0.029
Mab21l2	mab-21-like 2 (C. elegans)	0.029
Actn3	actinin alpha 3	0.029
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.029
Phlda2	pleckstrin homology-like domain, family A, member 2	0.029
Gm13290	predicted gene 13290	0.028
Rhcg	Rhesus blood group-associated C glycoprotein	0.028
Sumo1	SMT3 suppressor of mif two 3 homolog 1 (yeast)	0.028
Nkx6-1	NK6 homeobox 1	0.028
Msi1	Musashi homolog 1(Drosophila)	0.027
Foxf1a	forkhead box F1a	0.027
Guca2b	guanylate cyclase activator 2b (retina)	0.027
Tcfap2b	transcription factor AP-2 beta	0.027
Mep1a	meprin 1 alpha	0.026
Hmga2	high mobility group AT-hook 2	0.026
Wnt10a	wingless related MMTV integration site 10a	0.026
Gli1	GLI-Kruppel family member GLI1	0.026
Grem1	gremlin 1	0.026
Nos3	nitric oxide synthase 3, endothelial cell	0.026
Col22a1	collagen, type XXII, alpha 1	0.026
Arnt2	aryl hydrocarbon receptor nuclear translocator 2	0.026
Pthlh	parathyroid hormone-like peptide	0.025
Col4a4	collagen, type IV, alpha 4	0.025
Slc2a4	solute carrier family 2 (facilitated glucose transporter), member 4	0.025
Isl1	ISL1 transcription factor, LIM/homeodomain	0.025
Kif12	kinesin family member 12	0.025
Tgfbr3	transforming growth factor, beta receptor III	0.024
Ptch2	patched homolog 2	0.024
Cdh3	cadherin 3	0.024
Wnt4	wingless-related MMTV integration site 4	0.023
Irx1	Iroquois related homeobox 1 (Drosophila)	0.023
Cyp27b1	cytochrome P450, family 27, subfamily b, polypeptide 1	0.023
Igf2bp2	insulin-like growth factor 2 mRNA binding protein 2	0.023
Upk3b	uroplakin 3B	0.023
Pcdh12	protocadherin 12	0.023
Kcnj15	potassium inwardly-rectifying channel, subfamily J, member 15	0.023
Fzd4	frizzled homolog 4 (Drosophila)	0.022
Gata6	GATA binding protein 6	0.022
Trp63	transformation related protein 63	0.022
Lepr	leptin receptor	0.022
Cdh6	cadherin 6	0.021
Rgnef	Rho-guanine nucleotide exchange factor	0.021
Npr3	natriuretic peptide receptor 3	0.021
Wnt5b	wingless-related MMTV integration site 5B	0.021
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.021
Zic1	zinc finger protein of the cerebellum 1	0.021
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.021
Gpc3	glypican 3	0.021
Pax9	paired box gene 9	0.021
Ggnbp1	gametogenetin binding protein 1	0.021
Col11a1	collagen, type XI, alpha 1	0.020
Umod	uromodulin	0.020
Hoxd13	homeobox D13	0.020
Irx3	Iroquois related homeobox 3 (Drosophila)	0.020
Pou3f3	POU domain, class 3, transcription factor 3	0.020
Kap	kidney androgen regulated protein	0.020
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.020
Ror2	receptor tyrosine kinase-like orphan receptor 2	0.020
Irs3	insulin receptor substrate 3	0.020
Greb1	gene regulated by estrogen in breast cancer protein	0.020
Slc12a3	solute carrier family 12, member 3	0.019
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.019
Nrtn	neurturin	0.019
Osta	organic solute transporter alpha	0.019
Gfra3	glial cell line derived neurotrophic factor family receptor alpha 3	0.019
Ptgfr	prostaglandin F receptor	0.019
Fzd8	frizzled homolog 8 (Drosophila)	0.018
Kcnj1	potassium inwardly-rectifying channel, subfamily J, member 1	0.018
Efna5	ephrin A5	0.018
Egfr	epidermal growth factor receptor	0.018
Tchh	trichohyalin	0.018
Tlx2	T-cell leukemia, homeobox 2	0.018
Igf2bp1	insulin-like growth factor 2 mRNA binding protein 1	0.018
Robo3	roundabout homolog 3 (Drosophila)	0.018
Pou3f1	POU domain, class 3, transcription factor 1	0.018
Tal2	T-cell acute lymphocytic leukemia 2	0.018
Pou5f1	POU domain, class 5, transcription factor 1	0.018
Aqp2	aquaporin 2	0.017
Krt14	keratin 14	0.017
Slc22a6	solute carrier family 22 (organic anion transporter), member 6	0.017
Car12	carbonic anyhydrase 12	0.017
Six5	sine oculis-related homeobox 5 homolog (Drosophila)	0.017
Hs3st3a1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.017
Lama5	laminin, alpha 5	0.017
Pax7	paired box gene 7	0.017
Vgll2	vestigial like 2 homolog (Drosophila)	0.017
Capn6	calpain 6	0.017
Sprr2f	small proline-rich protein 2F	0.017
Zfp316	zinc finger protein 316	0.017
Casq1	calsequestrin 1	0.017
Guca2a	guanylate cyclase activator 2a (guanylin)	0.017
Sox9	SRY-box containing gene 9	0.016
Lhx5	LIM homeobox protein 5	0.016
Foxe3	forkhead box E3	0.016
Psg17	pregnancy specific glycoprotein 17	0.016
Aplnr	apelin receptor	0.016
Unc5c	unc-5 homolog C (C. elegans)	0.016
Plau	plasminogen activator, urokinase	0.016
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.016
Gata4	GATA binding protein 4	0.016
Pitx3	paired-like homeodomain transcription factor 3	0.016
Eya1	eyes absent 1 homolog (Drosophila)	0.016
Tnni1	troponin I, skeletal, slow 1	0.016
Nrk	Nik related kinase	0.015
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.015
Kl	klotho	0.015
Sox11	SRY-box containing gene 11	0.015
Pou3f2	POU domain, class 3, transcription factor 2	0.015
Lbx1	ladybird homeobox homolog 1 (Drosophila)	0.015
Bmpr1b	bone morphogenetic protein receptor, type 1B	0.015
Csf3	colony stimulating factor 3 (granulocyte)	0.015
Hnf4a	hepatic nuclear factor 4, alpha	0.015
Fxyd2	FXYD domain-containing ion transport regulator 2	0.015
Zbtb16	zinc finger and BTB domain containing 16	0.015
Aif1l	allograft inflammatory factor 1-like	0.014
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.014
Ephb2	Eph receptor B2	0.014
Dlx1	distal-less homeobox 1	0.014
Lef1	lymphoid enhancer binding factor 1	0.014
Phox2b	paired-like homeobox 2b	0.014
Col9a1	collagen, type IX, alpha 1	0.014
Foxi1	forkhead box I1	0.014
Rprm	reprimo, TP53 dependent G2 arrest mediator candidate	0.014
Aqp7	aquaporin 7	0.014
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.014
Lhx3	LIM homeobox protein 3	0.014
Pla2r1	phospholipase A2 receptor 1	0.014
Zfr2	zinc finger RNA binding protein 2	0.014
Gli2	GLI-Kruppel family member GLI2	0.014
Barx2	BarH-like homeobox 2	0.014
Meox1	mesenchyme homeobox 1	0.014
Mlph	melanophilin	0.014
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.014
Mecom	MDS1 and EVI1 complex locus	0.013
Myf5	myogenic factor 5	0.013
Hoxd12	homeobox D12	0.013
Col13a1	collagen, type XIII, alpha 1	0.013
Hmx1	H6 homeobox 1	0.013
Fgf6	fibroblast growth factor 6	0.013
Col2a1	collagen, type II, alpha 1	0.013
Lhx6	LIM homeobox protein 6	0.013
Fgf10	fibroblast growth factor 10	0.013
Cdsn	corneodesmosin	0.013
Meox2	mesenchyme homeobox 2	0.013
Foxl2	forkhead box L2	0.013
Hmx2	H6 homeobox 2	0.013
Cftr	cystic fibrosis transmembrane conductance regulator homolog	0.013
Hmx3	H6 homeobox 3	0.012
Atp4a	ATPase, H+/K+ exchanging, gastric, alpha polypeptide	0.012
Mst1r	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	0.012
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.012
Th	tyrosine hydroxylase	0.012
Insr	insulin receptor	0.012
T	brachyury	0.012
Hrc	histidine rich calcium binding protein	0.012
Prrx1	paired related homeobox 1	0.012
Gata3	GATA binding protein 3	0.012
Sox2	SRY-box containing gene 2	0.012
Dach1	dachshund 1 (Drosophila)	0.012
Adcyap1	adenylate cyclase activating polypeptide 1	0.012
Pax3	paired box gene 3	0.012
Cckar	cholecystokinin A receptor	0.012
Magel2	melanoma antigen, family L, 2	0.012
Sema5a	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.012
Scx	scleraxis	0.012
Ctnnb1	catenin (cadherin associated protein), beta 1	0.012
Foxd3	forkhead box D3	0.012
Miox	myo-inositol oxygenase	0.012
Ybx2	Y box protein 2	0.011
Nkx2-1	NK2 homeobox 1	0.011
Sox13	SRY-box containing gene 13	0.011
Evx2	even skipped homeotic gene 2 homolog	0.011
Slc4a1	solute carrier family 4 (anion exchanger), member 1	0.011
Ggt1	gamma-glutamyltransferase 1	0.011
Odz4	odd Oz/ten-m homolog 4 (Drosophila)	0.011
Nppc	natriuretic peptide type C	0.011
Dlx5	distal-less homeobox 5	0.011
Hnf1a	HNF1 homeobox A	0.011
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.011
Nkx2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.011
Egln3	EGL nine homolog 3 (C. elegans)	0.011
E330034G19Rik	RIKEN cDNA E330034G19 gene	0.011
Emid1	EMI domain containing 1	0.011
Sox17	SRY-box containing gene 17	0.011
St8sia2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.011
Foxc2	forkhead box C2	0.011
Wnt7b	wingless-related MMTV integration site 7B	0.011
Chrdl2	chordin-like 2	0.011
Col12a1	collagen, type XII, alpha 1	0.011
Cldn11	claudin 11	0.011
Npr1	natriuretic peptide receptor 1	0.010
Myl2	myosin, light polypeptide 2, regulatory, cardiac, slow	0.010
Pik3ca	phosphatidylinositol 3-kinase, catalytic, alpha polypeptide	0.010
Avpr2	arginine vasopressin receptor 2	0.010
Hoxb13	homeobox B13	0.010
Ppy	pancreatic polypeptide	0.010
Clcnkb	chloride channel Kb	0.010
Smad6	MAD homolog 6 (Drosophila)	0.010
Hnf1b	HNF1 homeobox B	0.010
Fgf15	fibroblast growth factor 15	0.010