IMP

Process View

Mus musculus

11 genes annotated in mouse

Multi-species View

hepatocyte apoptotic process

GO:0097284

Any apoptotic process in a hepatocyte, the main structural component of the liver.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "hepatocyte apoptotic process"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "hepatocyte apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
Bcl2l11	BCL2-like 11 (apoptosis facilitator)	0.959
Krt5	keratin 5	0.950	Mouse
Krt17	keratin 17	0.945	Mouse
Bax	BCL2-associated X protein	0.932	Mouse
Trp53	transformation related protein 53	0.903
Krt33b	keratin 33B	0.869	Mouse
Krt6a	keratin 6A	0.828	Mouse
Tlr4	toll-like receptor 4	0.776
Casp4	caspase 4, apoptosis-related cysteine peptidase	0.634	Mouse
Krt71	keratin 71	0.622	Mouse
Krtap8-1	keratin associated protein 8-1	0.616
Krt8	keratin 8	0.558
Krt18	keratin 18	0.519
Psapl1	prosaposin-like 1	0.511
Krtap3-1	keratin associated protein 3-1	0.510
Pkp1	plakophilin 1	0.494
Krt14	keratin 14	0.478	Mouse
Trp63	transformation related protein 63	0.468
Krt72-ps	keratin 72, pseudogene	0.464	Mouse
Casp1	caspase 1	0.429	Mouse
Pycard	PYD and CARD domain containing	0.428
Sprr1a	small proline-rich protein 1A	0.419
Wnt10a	wingless related MMTV integration site 10a	0.367
Casp8	caspase 8	0.323
Krt19	keratin 19	0.293	Mouse
Krt27	keratin 27	0.287	Mouse
Krt31	keratin 31	0.273	Mouse
Lgals7	lectin, galactose binding, soluble 7	0.252
Krt35	keratin 35	0.235	Mouse
Ppl	periplakin	0.212
Dlx3	distal-less homeobox 3	0.196
Sfn	stratifin	0.183
Krt32	keratin 32	0.178	Mouse
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.171
Tff1	trefoil factor 1	0.171
Pmaip1	phorbol-12-myristate-13-acetate-induced protein 1	0.164
Stk4	serine/threonine kinase 4	0.161
Casp3	caspase 3	0.159	Mouse
Syt8	synaptotagmin VIII	0.159
S100a3	S100 calcium binding protein A3	0.150
Krtap6-2	keratin associated protein 6-2	0.140
Krtap5-1	keratin associated protein 5-1	0.139
Krt86	keratin 86	0.138	Mouse
Rbl1	retinoblastoma-like 1 (p107)	0.136	Mouse
Alox12e	arachidonate lipoxygenase, epidermal	0.130
Gjb4	gap junction protein, beta 4	0.124
Hr	hairless	0.123
Krt13	keratin 13	0.120
Krt85	keratin 85	0.114
Hif1a	hypoxia inducible factor 1, alpha subunit	0.113
Gbp5	guanylate binding protein 5	0.109
Krt6b	keratin 6B	0.096	Mouse
Serpinb5	serine (or cysteine) peptidase inhibitor, clade B, member 5	0.096
Krt1	keratin 1	0.090	Mouse
Calm4	calmodulin 4	0.089
Asprv1	aspartic peptidase, retroviral-like 1	0.088
S100a14	S100 calcium binding protein A14	0.081
Pten	phosphatase and tensin homolog	0.080
Krt7	keratin 7	0.077	Mouse
Krt33a	keratin 33A	0.076	Mouse
Cdsn	corneodesmosin	0.076
Myd88	myeloid differentiation primary response gene 88	0.074
Krt84	keratin 84	0.072	Mouse
Il1f5	interleukin 1 family, member 5 (delta)	0.072
Sprr2d	small proline-rich protein 2D	0.063
Slurp1	secreted Ly6/Plaur domain containing 1	0.062
Mt4	metallothionein 4	0.059
Krt77	keratin 77	0.059	Mouse
Alox8	arachidonate 8-lipoxygenase	0.058
Krt36	keratin 36	0.056	Mouse
Apaf1	apoptotic peptidase activating factor 1	0.055
Krt34	keratin 34	0.054
Krt75	keratin 75	0.050	Mouse
Klk7	kallikrein related-peptidase 7 (chymotryptic, stratum corneum)	0.050
Atoh7	atonal homolog 7 (Drosophila)	0.049
Rbl2	retinoblastoma-like 2	0.049	Mouse
Il1r1	interleukin 1 receptor, type I	0.049
Cav1	caveolin 1, caveolae protein	0.048
Bak1	BCL2-antagonist/killer 1	0.047	Mouse
Cryaa	crystallin, alpha A	0.045
Gm10228	predicted gene 10228	0.044
Padi1	peptidyl arginine deiminase, type I	0.044
Oxt	oxytocin	0.044
Drd4	dopamine receptor D4	0.040
Sprr1b	small proline-rich protein 1B	0.040
Cd44	CD44 antigen	0.040
Krtap14	keratin associated protein 14	0.039
Crct1	cysteine-rich C-terminal 1	0.039
Terf1	telomeric repeat binding factor 1	0.038
Gpr87	G protein-coupled receptor 87	0.037
Ikbkg	inhibitor of kappaB kinase gamma	0.036
Wrn	Werner syndrome homolog (human)	0.035
Fam83f	family with sequence similarity 83, member F	0.035
Tgm3	transglutaminase 3, E polypeptide	0.033
Vhl	von Hippel-Lindau tumor suppressor	0.033
Rb1	retinoblastoma 1	0.033
Gm10229	predicted gene 10229	0.032
Map3k7	mitogen-activated protein kinase kinase kinase 7	0.032
Prss22	protease, serine, 22	0.031
Tnf	tumor necrosis factor	0.031
Tyr	tyrosinase	0.031
H2-M9	histocompatibility 2, M region locus 9	0.031
Atp2a1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.030
Lypd3	Ly6/Plaur domain containing 3	0.030
Ltbr	lymphotoxin B receptor	0.029
Lama5	laminin, alpha 5	0.029
Krtap3-3	keratin associated protein 3-3	0.029
Klk6	kallikrein related-peptidase 6	0.028
Trpm1	transient receptor potential cation channel, subfamily M, member 1	0.028
Pnpla6	patatin-like phospholipase domain containing 6	0.028
Adam10	a disintegrin and metallopeptidase domain 10	0.028
Dsc1	desmocollin 1	0.028
Itga3	integrin alpha 3	0.026
Fadd	Fas (TNFRSF6)-associated via death domain	0.026
Clic3	chloride intracellular channel 3	0.026
Krtdap	keratinocyte differentiation associated protein	0.026
Psors1c2	psoriasis susceptibility 1 candidate 2 (human)	0.026
Cbl	Casitas B-lineage lymphoma	0.025
Ctnnb1	catenin (cadherin associated protein), beta 1	0.024
Myc	myelocytomatosis oncogene	0.024
Nphp4	nephronophthisis 4 (juvenile) homolog (human)	0.024
Ivl	involucrin	0.024
Zp2	zona pellucida glycoprotein 2	0.023
Amelx	amelogenin X chromosome	0.023
Trim29	tripartite motif-containing 29	0.023
Sftpc	surfactant associated protein C	0.023
Cldn7	claudin 7	0.022
Padi3	peptidyl arginine deiminase, type III	0.022
Nfkb2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100	0.021
Crhr2	corticotropin releasing hormone receptor 2	0.021
Gpr143	G protein-coupled receptor 143	0.021
Car6	carbonic anhydrase 6	0.021
Barx2	BarH-like homeobox 2	0.021
Wfdc2	WAP four-disulfide core domain 2	0.021
Krtap8-2	keratin associated protein 8-2	0.020
Nfe2l2	nuclear factor, erythroid derived 2, like 2	0.020
Ppp1cc	protein phosphatase 1, catalytic subunit, gamma isoform	0.020
Il18	interleukin 18	0.020
Krt4	keratin 4	0.019	Mouse
Pkp3	plakophilin 3	0.019
Sult2b1	sulfotransferase family, cytosolic, 2B, member 1	0.019
Chuk	conserved helix-loop-helix ubiquitous kinase	0.019
E2f1	E2F transcription factor 1	0.019
Arhgdia	Rho GDP dissociation inhibitor (GDI) alpha	0.019
Sprr2h	small proline-rich protein 2H	0.019
Edn2	endothelin 2	0.019
Casp7	caspase 7	0.019	Mouse
Cldn4	claudin 4	0.019
Cyp2b19	cytochrome P450, family 2, subfamily b, polypeptide 19	0.019
Krtap16-8	keratin associated protein 16-8	0.019
Slc46a2	solute carrier family 46, member 2	0.018
Itgb1	integrin beta 1 (fibronectin receptor beta)	0.018
Epha2	Eph receptor A2	0.018
Ptgs2	prostaglandin-endoperoxide synthase 2	0.018
Cdcp1	CUB domain containing protein 1	0.018
Capn8	calpain 8	0.018
2310014L17Rik	RIKEN cDNA 2310014L17 gene	0.018
Krt81	keratin 81	0.017	Mouse
Krtap12-1	keratin associated protein 12-1	0.017
Dsc3	desmocollin 3	0.017
Foxn1	forkhead box N1	0.017
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.017
Lce1a1	late cornified envelope 1A1	0.017
Ly6g6c	lymphocyte antigen 6 complex, locus G6C	0.017
Igh	immunoglobulin heavy chain complex	0.017
Evpl	envoplakin	0.017
Sftpd	surfactant associated protein D	0.016
Stat6	signal transducer and activator of transcription 6	0.016
Csnk1d	casein kinase 1, delta	0.016
Birc3	baculoviral IAP repeat-containing 3	0.016
Mdfi	MyoD family inhibitor	0.016
Pax1	paired box gene 1	0.016
Pthlh	parathyroid hormone-like peptide	0.016
Krtap13-1	keratin associated protein 13-1	0.015
Ripk3	receptor-interacting serine-threonine kinase 3	0.015
Wls	wntless homolog (Drosophila)	0.015
Ucn	urocortin	0.015
Gipc1	GIPC PDZ domain containing family, member 1	0.015
Tgm2	transglutaminase 2, C polypeptide	0.015
Ghrl	ghrelin	0.014
Dmkn	dermokine	0.014
Krt79	keratin 79	0.014
Nppc	natriuretic peptide type C	0.014
Atp4b	ATPase, H+/K+ exchanging, beta polypeptide	0.014
Tjap1	tight junction associated protein 1	0.014
Krtap13	keratin associated protein 13	0.014
Cyld	cylindromatosis (turban tumor syndrome)	0.014
Slc25a48	solute carrier family 25, member 48	0.014
Dlx4	distal-less homeobox 4	0.014
Bid	BH3 interacting domain death agonist	0.014
Pcdha10	protocadherin alpha 10	0.014
Aim2	absent in melanoma 2	0.014
Nfya	nuclear transcription factor-Y alpha	0.014
Selp	selectin, platelet	0.014
Krtap16-4	keratin associated protein 16-4	0.014
Htr7	5-hydroxytryptamine (serotonin) receptor 7	0.013
Plscr1	phospholipid scramblase 1	0.013
Stk3	serine/threonine kinase 3 (Ste20, yeast homolog)	0.013
Pla2g4f	phospholipase A2, group IVF	0.013
Lce1b	late cornified envelope 1B	0.013
Eda	ectodysplasin-A	0.013
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.013
Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B	0.013
Cdh3	cadherin 3	0.013
Casp14	caspase 14	0.013	Mouse
Ikbkb	inhibitor of kappaB kinase beta	0.013
Col17a1	collagen, type XVII, alpha 1	0.012
Mfn2	mitofusin 2	0.012
Tnni2	troponin I, skeletal, fast 2	0.012
Guca2b	guanylate cyclase activator 2b (retina)	0.012
Rab25	RAB25, member RAS oncogene family	0.012
Tacstd2	tumor-associated calcium signal transducer 2	0.011
Gfap	glial fibrillary acidic protein	0.011
Phlda2	pleckstrin homology-like domain, family A, member 2	0.011
Krt15	keratin 15	0.011	Mouse
Lad1	ladinin	0.011
Lce1i	late cornified envelope 1I	0.011
Prss30	protease, serine, 30	0.011
Papss1	3'-phosphoadenosine 5'-phosphosulfate synthase 1	0.011
Ly96	lymphocyte antigen 96	0.011
Rcvrn	recoverin	0.011
Prkci	protein kinase C, iota	0.011
Padi4	peptidyl arginine deiminase, type IV	0.011
Ptk6	PTK6 protein tyrosine kinase 6	0.011
Fgf9	fibroblast growth factor 9	0.011
Krt25	keratin 25	0.010	Mouse
Smr3a	submaxillary gland androgen regulated protein 3A	0.010
Cacng1	calcium channel, voltage-dependent, gamma subunit 1	0.010
Nat2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	0.010
Expi	extracellular proteinase inhibitor	0.010
Psca	prostate stem cell antigen	0.010
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.010
Vwa5a	von Willebrand factor A domain containing 5A	0.010
Ptpn5	protein tyrosine phosphatase, non-receptor type 5	0.010
Fas	Fas (TNF receptor superfamily member 6)	0.010