IMP

Process View

Mus musculus

10 genes annotated in mouse

loop of henle development

GO:0072070

The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.

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Known genes in the process in mouse Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "loop of henle development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "loop of henle development" (in gray)

Name	Description	Probability	Func Analog Organism
Pax2	paired box gene 2	1.000
Sox2	SRY-box containing gene 2	0.998
Otx2	orthodenticle homolog 2 (Drosophila)	0.996
Emx2	empty spiracles homolog 2 (Drosophila)	0.986
Chd7	chromodomain helicase DNA binding protein 7	0.985
Notch1	Notch gene homolog 1 (Drosophila)	0.960
Hes5	hairy and enhancer of split 5 (Drosophila)	0.958
Otx1	orthodenticle homolog 1 (Drosophila)	0.953
Emx1	empty spiracles homolog 1 (Drosophila)	0.944
Lhx1	LIM homeobox protein 1	0.939
Hmx3	H6 homeobox 3	0.933
Shh	sonic hedgehog	0.931
Lmx1a	LIM homeobox transcription factor 1 alpha	0.906
Gli3	GLI-Kruppel family member GLI3	0.904
Nog	noggin	0.903
Pax8	paired box gene 8	0.845
Lhx3	LIM homeobox protein 3	0.830
Fgf8	fibroblast growth factor 8	0.810
Hes1	hairy and enhancer of split 1 (Drosophila)	0.802	Mouse
Pitx2	paired-like homeodomain transcription factor 2	0.761
Foxg1	forkhead box G1	0.744
Wnt3a	wingless-related MMTV integration site 3A	0.719	Mouse
Fgfr1	fibroblast growth factor receptor 1	0.714
Rarg	retinoic acid receptor, gamma	0.682
Six1	sine oculis-related homeobox 1 homolog (Drosophila)	0.668
Vax1	ventral anterior homeobox containing gene 1	0.656
Pou4f3	POU domain, class 4, transcription factor 3	0.642	Mouse
Gdnf	glial cell line derived neurotrophic factor	0.628
En1	engrailed 1	0.600
Dll1	delta-like 1 (Drosophila)	0.591
T	brachyury	0.567
Jag1	jagged 1	0.567
Rbpj	recombination signal binding protein for immunoglobulin kappa J region	0.563
Nanog	Nanog homeobox	0.530
Fgfr2	fibroblast growth factor receptor 2	0.522
Kcne1	potassium voltage-gated channel, Isk-related subfamily, member 1	0.487
Sall3	sal-like 3 (Drosophila)	0.462
Irx2	Iroquois related homeobox 2 (Drosophila)	0.424
Tlx3	T-cell leukemia, homeobox 3	0.422
Hoxd13	homeobox D13	0.414
Sox3	SRY-box containing gene 3	0.398
Vangl2	vang-like 2 (van gogh, Drosophila)	0.393
Ptk7	PTK7 protein tyrosine kinase 7	0.392
Hmx1	H6 homeobox 1	0.379
Dkk1	dickkopf homolog 1 (Xenopus laevis)	0.362
Kcnq1	potassium voltage-gated channel, subfamily Q, member 1	0.354
Irx1	Iroquois related homeobox 1 (Drosophila)	0.336
Tcfap2c	transcription factor AP-2, gamma	0.287
Fgf15	fibroblast growth factor 15	0.280
Pou3f3	POU domain, class 3, transcription factor 3	0.279
Irx5	Iroquois related homeobox 5 (Drosophila)	0.269	Mouse
Lmx1b	LIM homeobox transcription factor 1 beta	0.259
Jag2	jagged 2	0.239	Mouse
Pax6	paired box gene 6	0.238
Wnt1	wingless-related MMTV integration site 1	0.231	Mouse
Foxc1	forkhead box C1	0.225
Sox1	SRY-box containing gene 1	0.204
Hoxd11	homeobox D11	0.204
Fgf3	fibroblast growth factor 3	0.202
Tbx10	T-box 10	0.197
Wnt6	wingless-related MMTV integration site 6	0.186	Mouse
Pax3	paired box gene 3	0.173
Hoxa13	homeobox A13	0.173
Foxi1	forkhead box I1	0.168
Eya1	eyes absent 1 homolog (Drosophila)	0.163
Lhx5	LIM homeobox protein 5	0.154
Pitx3	paired-like homeodomain transcription factor 3	0.149
Nodal	nodal	0.148
Uncx	UNC homeobox	0.146
Nkx1-2	NK1 transcription factor related, locus 2 (Drosophila)	0.137
Fgf18	fibroblast growth factor 18	0.133
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.131
Gata3	GATA binding protein 3	0.124
Nr2e1	nuclear receptor subfamily 2, group E, member 1	0.122
Sftpb	surfactant associated protein B	0.121
Six6	sine oculis-related homeobox 6 homolog (Drosophila)	0.120
Gbx2	gastrulation brain homeobox 2	0.112
Insm1	insulinoma-associated 1	0.109
Foxh1	forkhead box H1	0.106
Pax1	paired box gene 1	0.106
Nrtn	neurturin	0.101
Slc26a4	solute carrier family 26, member 4	0.098
Tbx1	T-box 1	0.089
Slc32a1	solute carrier family 32 (GABA vesicular transporter), member 1	0.086
Chrm1	cholinergic receptor, muscarinic 1, CNS	0.086
Sall4	sal-like 4 (Drosophila)	0.085
Atoh7	atonal homolog 7 (Drosophila)	0.085
Srrm4	serine/arginine repetitive matrix 4	0.084
Tbx2	T-box 2	0.083
Wnt9b	wingless-type MMTV integration site 9B	0.083	Mouse
Cdx1	caudal type homeobox 1	0.082
Zic2	zinc finger protein of the cerebellum 2	0.081
Wnt4	wingless-related MMTV integration site 4	0.080	Mouse
Sall1	sal-like 1 (Drosophila)	0.077
Hoxa4	homeobox A4	0.077
Sox17	SRY-box containing gene 17	0.075
Neurog1	neurogenin 1	0.073
Nkx6-1	NK6 homeobox 1	0.072
BC024139	cDNA sequence BC024139	0.071
Bicc1	bicaudal C homolog 1 (Drosophila)	0.069
Krt15	keratin 15	0.068
Pvrl1	poliovirus receptor-related 1	0.067
Smad6	MAD homolog 6 (Drosophila)	0.067
Wt1	Wilms tumor 1 homolog	0.066
Foxn4	forkhead box N4	0.065
Hoxa11	homeobox A11	0.064
Oprd1	opioid receptor, delta 1	0.060
Pou3f2	POU domain, class 3, transcription factor 2	0.059	Mouse
Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	0.056
Bcl2	B-cell leukemia/lymphoma 2	0.056
Bnc1	basonuclin 1	0.055
Foxb1	forkhead box B1	0.055
Lhx4	LIM homeobox protein 4	0.053
Msx3	homeobox, msh-like 3	0.053
Lama5	laminin, alpha 5	0.052
Onecut1	one cut domain, family member 1	0.051
Efnb2	ephrin B2	0.048
Sox21	SRY-box containing gene 21	0.047
Foxf1a	forkhead box F1a	0.047
Crlf1	cytokine receptor-like factor 1	0.046
Tbx6	T-box 6	0.045
Tctex1d4	Tctex1 domain containing 4	0.045
Prop1	paired like homeodomain factor 1	0.044
Notch2	Notch gene homolog 2 (Drosophila)	0.044
Invs	inversin	0.043
Il11	interleukin 11	0.042
Hoxd3	homeobox D3	0.042
Six3	sine oculis-related homeobox 3 homolog (Drosophila)	0.040
Efna4	ephrin A4	0.038
Cdh23	cadherin 23 (otocadherin)	0.038
Hoxd9	homeobox D9	0.038
Rax	retina and anterior neural fold homeobox	0.038
Tcfcp2l1	transcription factor CP2-like 1	0.038
Clic3	chloride intracellular channel 3	0.037
Nrarp	Notch-regulated ankyrin repeat protein	0.037
Zic3	zinc finger protein of the cerebellum 3	0.037
Krtdap	keratinocyte differentiation associated protein	0.036
Ngfr	nerve growth factor receptor (TNFR superfamily, member 16)	0.036
Sim2	single-minded homolog 2 (Drosophila)	0.036
Irx3	Iroquois related homeobox 3 (Drosophila)	0.035
Col4a3	collagen, type IV, alpha 3	0.035
Fgf4	fibroblast growth factor 4	0.034
Dlx1	distal-less homeobox 1	0.034
Foxn1	forkhead box N1	0.034
Smo	smoothened homolog (Drosophila)	0.034
Mnx1	motor neuron and pancreas homeobox 1	0.034
Myo6	myosin VI	0.033
Cys1	cystin 1	0.033
Wnt7b	wingless-related MMTV integration site 7B	0.032
Hoxa10	homeobox A10	0.032
Fzd10	frizzled homolog 10 (Drosophila)	0.032
Nkx2-2	NK2 transcription factor related, locus 2 (Drosophila)	0.032
Efna2	ephrin A2	0.032
Artn	artemin	0.031
Kcne1l	potassium voltage-gated channel, Isk-related family, member 1-like, pseudogene	0.030
Fzd8	frizzled homolog 8 (Drosophila)	0.030
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.030
Ptf1a	pancreas specific transcription factor, 1a	0.030
Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.029
Tbx5	T-box 5	0.029
Ptprb	protein tyrosine phosphatase, receptor type, B	0.029
Pou3f1	POU domain, class 3, transcription factor 1	0.029	Mouse
Gja3	gap junction protein, alpha 3	0.029
Dmgdh	dimethylglycine dehydrogenase precursor	0.029
Robo3	roundabout homolog 3 (Drosophila)	0.029
Gpr50	G-protein-coupled receptor 50	0.029
S1pr2	sphingosine-1-phosphate receptor 2	0.028
Hoxa1	homeobox A1	0.028
Hmx2	H6 homeobox 2	0.028
Slc25a29	solute carrier family 25 (mitochondrial carrier, palmitoylcarnitine transporter), member 29	0.028
Btbd17	BTB (POZ) domain containing 17	0.028
Wnt10a	wingless related MMTV integration site 10a	0.028
Meox2	mesenchyme homeobox 2	0.027
Zfp771	zinc finger protein 771	0.027
Drd2	dopamine receptor D2	0.027
Slc22a12	solute carrier family 22 (organic anion/cation transporter), member 12	0.027
Irx4	Iroquois related homeobox 4 (Drosophila)	0.027	Mouse
Csf2	colony stimulating factor 2 (granulocyte-macrophage)	0.026
Fgf17	fibroblast growth factor 17	0.026
Hes3	hairy and enhancer of split 3 (Drosophila)	0.026	Mouse
Rhbdl3	rhomboid, veinlet-like 3 (Drosophila)	0.026
4931408A02Rik	RIKEN cDNA 4931408A02 gene	0.026
Foxd2	forkhead box D2	0.026
Zfp703	zinc finger protein 703	0.025
Foxe3	forkhead box E3	0.025
Adrb1	adrenergic receptor, beta 1	0.025
Sox8	SRY-box containing gene 8	0.025
Fgf10	fibroblast growth factor 10	0.025
Fjx1	four jointed box 1 (Drosophila)	0.025
Igdcc3	immunoglobulin superfamily, DCC subclass, member 3	0.025
Evx2	even skipped homeotic gene 2 homolog	0.024
Tlx2	T-cell leukemia, homeobox 2	0.024
Tead3	TEA domain family member 3	0.024
Etv2	ets variant gene 2	0.024
Barx2	BarH-like homeobox 2	0.023
Nkx2-1	NK2 homeobox 1	0.023
Fzd6	frizzled homolog 6 (Drosophila)	0.023
Grid1	glutamate receptor, ionotropic, delta 1	0.023
Mycl1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	0.023
Dact1	dapper homolog 1, antagonist of beta-catenin (xenopus)	0.023
Zfp503	zinc finger protein 503	0.022
Pax7	paired box gene 7	0.022
Lef1	lymphoid enhancer binding factor 1	0.022
Isl1	ISL1 transcription factor, LIM/homeodomain	0.021
Mt4	metallothionein 4	0.021
Psen1	presenilin 1	0.021
Hoxd1	homeobox D1	0.021
Bdnf	brain derived neurotrophic factor	0.021
Ush1g	Usher syndrome 1G homolog (human)	0.021
Tbx3	T-box 3	0.020
Sema6c	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C	0.020
Rarb	retinoic acid receptor, beta	0.020
Hoxa7	homeobox A7	0.020
Foxb2	forkhead box B2	0.020
Sim1	single-minded homolog 1 (Drosophila)	0.020
Foxd3	forkhead box D3	0.020
Nos3	nitric oxide synthase 3, endothelial cell	0.020
Madcam1	mucosal vascular addressin cell adhesion molecule 1	0.020
Fgf5	fibroblast growth factor 5	0.020
Tulp1	tubby like protein 1	0.019
Barx1	BarH-like homeobox 1	0.019
Snai1	snail homolog 1 (Drosophila)	0.019
Gdf11	growth differentiation factor 11	0.019
Calm4	calmodulin 4	0.019
Kcnj10	potassium inwardly-rectifying channel, subfamily J, member 10	0.019
Slc6a3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.019
Hoxb13	homeobox B13	0.018
Gipc3	GIPC PDZ domain containing family, member 3	0.018
Dlx4	distal-less homeobox 4	0.018
BC018465	cDNA sequence BC018465	0.018
Gli2	GLI-Kruppel family member GLI2	0.018
Espn	espin	0.018
2610109H07Rik	RIKEN cDNA 2610109H07 gene	0.018
Dmbx1	diencephalon/mesencephalon homeobox 1	0.018
Edar	ectodysplasin-A receptor	0.018
Twist2	twist homolog 2 (Drosophila)	0.018
Pcdh12	protocadherin 12	0.018
Slc34a2	solute carrier family 34 (sodium phosphate), member 2	0.018
Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.018
Olig3	oligodendrocyte transcription factor 3	0.017
Barhl1	BarH-like 1 (Drosophila)	0.017
Rspo1	R-spondin homolog (Xenopus laevis)	0.017
Amh	anti-Mullerian hormone	0.017
Lyzl4	lysozyme-like 4	0.017
Col22a1	collagen, type XXII, alpha 1	0.017
Efnb1	ephrin B1	0.017
En2	engrailed 2	0.017
Vstm2b	V-set and transmembrane domain containing 2B	0.017
Wnt5b	wingless-related MMTV integration site 5B	0.017	Mouse
Phlda2	pleckstrin homology-like domain, family A, member 2	0.017
Zic1	zinc finger protein of the cerebellum 1	0.016
Gli1	GLI-Kruppel family member GLI1	0.016
2310002J15Rik	RIKEN cDNA 2310002J15 gene	0.016
Sox11	SRY-box containing gene 11	0.016
Ptger1	prostaglandin E receptor 1 (subtype EP1)	0.016
Msi1	Musashi homolog 1(Drosophila)	0.016
Ttc16	tetratricopeptide repeat domain 16	0.016
Crygd	crystallin, gamma D	0.016
Etv4	ets variant gene 4 (E1A enhancer binding protein, E1AF)	0.016
Arvcf	armadillo repeat gene deleted in velo-cardio-facial syndrome	0.016
Zbtb12	zinc finger and BTB domain containing 12	0.016
Acan	aggrecan	0.015
H1fx	H1 histone family, member X	0.015
Mixl1	Mix1 homeobox-like 1 (Xenopus laevis)	0.015
Cer1	cerberus 1 homolog (Xenopus laevis)	0.015
Kcnj5	potassium inwardly-rectifying channel, subfamily J, member 5	0.015
Gsx1	GS homeobox 1	0.015
Gjb4	gap junction protein, beta 4	0.015
Gsx2	GS homeobox 2	0.015
Six2	sine oculis-related homeobox 2 homolog (Drosophila)	0.015
5430421N21Rik	RIKEN cDNA 5430421N21 gene	0.015
Muc5ac	mucin 5, subtypes A and C, tracheobronchial/gastric	0.015
Gja4	gap junction protein, alpha 4	0.015
Socs1	suppressor of cytokine signaling 1	0.015
Gata6	GATA binding protein 6	0.015
Gpr27	G protein-coupled receptor 27	0.015
Trp73	transformation related protein 73	0.015
Olfr70	olfactory receptor 70	0.015
AI118078	expressed sequence AI118078	0.015
Cilp2	cartilage intermediate layer protein 2	0.014
Adra2b	adrenergic receptor, alpha 2b	0.014
Epha8	Eph receptor A8	0.014
Cox4i2	cytochrome c oxidase subunit IV isoform 2	0.014
Crybb2	crystallin, beta B2	0.014
Hba-x	hemoglobin X, alpha-like embryonic chain in Hba complex	0.014
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.014
Klf3	Kruppel-like factor 3 (basic)	0.014
Atoh1	atonal homolog 1 (Drosophila)	0.014
Matn4	matrilin 4	0.013
Porcn	porcupine homolog (Drosophila)	0.013
Ephb3	Eph receptor B3	0.013
Slc16a8	solute carrier family 16 (monocarboxylic acid transporters), member 8	0.013
3110079O15Rik	RIKEN cDNA 3110079O15 gene	0.013
Efnb3	ephrin B3	0.013
Slurp1	secreted Ly6/Plaur domain containing 1	0.013
Bik	BCL2-interacting killer	0.013
Hsd11b2	hydroxysteroid 11-beta dehydrogenase 2	0.013
Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.013
Notch3	Notch gene homolog 3 (Drosophila)	0.013
Rb1	retinoblastoma 1	0.013
Ntn3	netrin 3	0.013
Gata4	GATA binding protein 4	0.013
C1ql1	complement component 1, q subcomponent-like 1	0.013
Tcl1	T-cell lymphoma breakpoint 1	0.013
Spdef	SAM pointed domain containing ets transcription factor	0.012
Zbtb7c	zinc finger and BTB domain containing 7C	0.012
Hoxb7	homeobox B7	0.012
Bcam	basal cell adhesion molecule	0.012
Slc14a2	solute carrier family 14 (urea transporter), member 2	0.012
Aif1l	allograft inflammatory factor 1-like	0.012
Foxd4	forkhead box D4	0.012
Megf8	multiple EGF-like-domains 8	0.012
Wnt8a	wingless-related MMTV integration site 8A	0.012	Mouse
Igfbpl1	insulin-like growth factor binding protein-like 1	0.012
Matn3	matrilin 3	0.012
Kcnj4	potassium inwardly-rectifying channel, subfamily J, member 4	0.012
Hoxb6	homeobox B6	0.012
Usp43	ubiquitin specific peptidase 43	0.012
Lrp6	low density lipoprotein receptor-related protein 6	0.012
E130012A19Rik	RIKEN cDNA E130012A19 gene	0.012
Prx	periaxin	0.012
Tcf15	transcription factor 15	0.012
Ptcra	pre T-cell antigen receptor alpha	0.012
Emid2	EMI domain containing 2	0.012
Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	0.012
Slit1	slit homolog 1 (Drosophila)	0.012
Wwc2	WW, C2 and coiled-coil domain containing 2	0.012
Zfp42	zinc finger protein 42	0.011
Lama1	laminin, alpha 1	0.011
Fgf16	fibroblast growth factor 16	0.011
Hnf1b	HNF1 homeobox B	0.011
Psca	prostate stem cell antigen	0.011
Nobox	NOBOX oogenesis homeobox	0.011
Sox14	SRY-box containing gene 14	0.011
Hesx1	homeobox gene expressed in ES cells	0.011
Hoxc9	homeobox C9	0.011
Chad	chondroadherin	0.011
Eng	endoglin	0.011
Slc12a1	solute carrier family 12, member 1	0.011
Nfe2l3	nuclear factor, erythroid derived 2, like 3	0.011
Clcnkb	chloride channel Kb	0.011
Lrp5	low density lipoprotein receptor-related protein 5	0.011
Cdx2	caudal type homeobox 2	0.011
Npas1	neuronal PAS domain protein 1	0.011
Pcdh15	protocadherin 15	0.011
Nxph4	neurexophilin 4	0.011
Duoxa1	dual oxidase maturation factor 1	0.011
Nkx2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.011
Sct	secretin	0.011
Fxyd2	FXYD domain-containing ion transport regulator 2	0.010
Ror1	receptor tyrosine kinase-like orphan receptor 1	0.010
Krt14	keratin 14	0.010
Fign	fidgetin	0.010
Foxl2	forkhead box L2	0.010
Tmem198	transmembrane protein 198	0.010
Dmrt3	doublesex and mab-3 related transcription factor 3	0.010
Sox7	SRY-box containing gene 7	0.010
U46068	cDNA sequence U46068	0.010