IMP

Process View

Rattus norvegicus

4 genes annotated in rat

cell differentiation involved in kidney development

The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.

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Known genes in the process in rat Include functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cell differentiation involved in kidney development"

Show only novel predictions Show only unknown genes Highlight genes with functional analogs involved in "cell differentiation involved in kidney development" (in gray)

Name	Description	Probability	Func Analog Organism
Baiap2	BAI1-associated protein 2	0.474
Myh9	myosin, heavy chain 9, non-muscle	0.335
Ctnnd2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.240
Tgfbr3	transforming growth factor, beta receptor III	0.213
Itpr2	inositol 1,4,5-triphosphate receptor, type 2	0.197
LOC100362108	poly (ADP-ribose) polymerase family, member 10	0.195
Ctnnd1	catenin (cadherin associated protein), delta 1	0.171
Flt1	FMS-related tyrosine kinase 1	0.169
Timp3	TIMP metallopeptidase inhibitor 3	0.163
Rnf213	ring finger protein 213	0.145
Tgfbr2	transforming growth factor, beta receptor II	0.140
Lig3	ligase III, DNA, ATP-dependent	0.138
Nek9	NIMA (never in mitosis gene a)- related kinase 9	0.131
LOC100365106	rCG32755-like	0.118
Dlg1	discs, large homolog 1 (Drosophila)	0.115
Nfkb1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.114
Ahr	aryl hydrocarbon receptor	0.105
Gja5	gap junction protein, alpha 5	0.104
Limd1	LIM domains containing 1	0.097
Prkch	protein kinase C, eta	0.094
Ptpn14	protein tyrosine phosphatase, non-receptor type 14	0.091
Hdac7	histone deacetylase 7	0.088
Clic4	chloride intracellular channel 4	0.086
Gata3	GATA binding protein 3	0.078	Mouse
Mtus1	mitochondrial tumor suppressor 1	0.072
Amelx	amelogenin X chromosome	0.071
Iqgap1	IQ motif containing GTPase activating protein 1	0.069
Efnb1	ephrin B1	0.068
Parp14	poly (ADP-ribose) polymerase family, member 14	0.068
Lgals3bp	lectin, galactoside-binding, soluble, 3 binding protein	0.066
Sp110	SP110 nuclear body protein	0.066
Hoxc4	homeo box C4	0.064
Plxnb2	plexin B2	0.064
Nfix	nuclear factor I/X (CCAAT-binding transcription factor)	0.063
Prdm2	PR domain containing 2, with ZNF domain	0.062
Stat2	signal transducer and activator of transcription 2	0.062	Rat
Cad	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.060
Rps6ka1	ribosomal protein S6 kinase polypeptide 1	0.056
Nos3	nitric oxide synthase 3, endothelial cell	0.053
Mov10	Moloney leukemia virus 10	0.051
Krt15	keratin 15	0.049
Smad7	SMAD family member 7	0.047
Fgfr1	Fibroblast growth factor receptor 1	0.046
Itpr3	inositol 1,4,5-triphosphate receptor, type 3	0.045
Inppl1	inositol polyphosphate phosphatase-like 1	0.043
Tcf12	transcription factor 12	0.042
Nab1	Ngfi-A binding protein 1	0.041
Igtp	interferon gamma induced GTPase	0.040
Cxxc4	CXXC finger 4	0.040
Rara	retinoic acid receptor, alpha	0.040
Sv2a	synaptic vesicle glycoprotein 2a	0.040
Eif2ak2	eukaryotic translation initiation factor 2-alpha kinase 2	0.039
Ghrh	growth hormone releasing hormone	0.039
Plekhg2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	0.039
Ide	insulin degrading enzyme	0.038
Egfl7	EGF-like-domain, multiple 7	0.038
Rasip1	Ras interacting protein 1	0.037
Acvr1	activin A receptor, type I	0.036
Ehd4	EH-domain containing 4	0.034
Adam10	ADAM metallopeptidase domain 10	0.034
Trim5	tripartite motif-containing 5	0.034
Ptgir	prostaglandin I2 (prostacyclin) receptor (IP)	0.034
Casp2	caspase 2	0.033
Cmklr1	chemokine-like receptor 1	0.033
Nr2f2	nuclear receptor subfamily 2, group F, member 2	0.031
Olr1469	olfactory receptor Olr1469	0.031
Fut4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	0.031
Pim1	pim-1 oncogene	0.030
Utrn	utrophin	0.030
Mapk9	mitogen-activated protein kinase 9	0.029
Rxra	retinoid X receptor alpha	0.029
Frmd4b	FERM domain containing 4B	0.029
Rin2	Ras and Rab interactor 2	0.029
Hist1h1d	histone cluster 1, H1d	0.028
Myo1b	myosin Ib	0.028
Sdc1	syndecan 1	0.027
Tcf3	transcription factor 3	0.027
Pdcl	phosducin-like	0.026
Zfp36	zinc finger protein 36	0.026
Smad1	SMAD family member 1	0.026
Hoxd3	homeo box D3	0.026
Tgoln1	trans-golgi network protein	0.026
Il6st	interleukin 6 signal transducer	0.026
LOC245710	PSD-95 binding protein	0.025
Jak2	Janus kinase 2	0.025
Bmp7	bone morphogenetic protein 7	0.025
Tfeb	transcription factor EB	0.025
Kif27	kinesin family member 27	0.024
Cd2ap	CD2-associated protein	0.024
Tead3	TEA domain family member 3	0.024
Ascl1	achaete-scute complex homolog 1 (Drosophila)	0.024
A4galt	alpha 1,4-galactosyltransferase	0.023
Irf7	interferon regulatory factor 7	0.023
Magi2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.023
Bcl2	B-cell CLL/lymphoma 2	0.023
Myo9b	myosin IXb	0.023
Nrarp	Notch-regulated ankyrin repeat protein	0.022
Degs2	degenerative spermatocyte homolog 2, lipid desaturase (Drosophila)	0.022
Lhx1	LIM homeobox 1	0.022	Mouse
Elovl5	ELOVL family member 5, elongation of long chain fatty acids (yeast)	0.022
Il13ra1	interleukin 13 receptor, alpha 1	0.021
Acap1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	0.021
Rest	RE1-silencing transcription factor	0.021
Mx2	myxovirus (influenza virus) resistance 2	0.021
Ptger4	prostaglandin E receptor 4 (subtype EP4)	0.021
Gata2	GATA binding protein 2	0.021
Sardh	sarcosine dehydrogenase	0.021
Pak2	p21 protein (Cdc42/Rac)-activated kinase 2	0.020
Klf13	Kruppel-like factor 13	0.020
Steap2	six transmembrane epithelial antigen of the prostate 2	0.020
Itga6	integrin, alpha 6	0.020
Nfia	nuclear factor I/A	0.020
Olfm1	olfactomedin 1	0.020
Hspa12b	heat shock protein 12B	0.020
Thbd	thrombomodulin	0.020
Actn4	actinin alpha 4	0.020
Gata6	GATA binding protein 6	0.020
Jub	jub, ajuba homolog (Xenopus laevis)	0.019
Pank2	pantothenate kinase 2 (Hallervorden-Spatz syndrome)	0.019
Sox13	SRY (sex determining region Y)-box 13	0.019
Gse1	genetic suppressor element 1	0.019
Kng1	kininogen 1	0.019
Kdr	kinase insert domain receptor	0.019
Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.019
Pax8	paired box 8	0.019	Mouse
Tnfrsf1b	tumor necrosis factor receptor superfamily, member 1b	0.019
Ace	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.019
Rela	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.019
Hoxd9	homeo box D9	0.019
Cdc42se1	CDC42 small effector 1	0.019
Triobp	TRIO and F-actin binding protein	0.018
Ptges	prostaglandin E synthase	0.018
Art2	ADP-ribosyltransferase 2	0.018
A2m	alpha-2-macroglobulin	0.018
Abcc1	ATP-binding cassette, subfamily C (CFTR/MRP), member 1	0.018
Ddx58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.018
Sirpa	signal-regulatory protein alpha	0.018
Cyth3	cytohesin 3	0.018
Stat1	signal transducer and activator of transcription 1	0.018
Prss37	protease, serine, 37	0.018
Ntm	neurotrimin	0.018
Podxl	podocalyxin-like	0.018
Lef1	lymphoid enhancer binding factor 1	0.018
Cdgap	Cdc42 GTPase-activating protein	0.017
Irs1	insulin receptor substrate 1	0.017
Olfml2a	olfactomedin-like 2A	0.017
Ptk7	PTK7 protein tyrosine kinase 7	0.017
Tln1	talin 1	0.017
Dcaf17	DDB1 and CUL4 associated factor 17	0.017
Pdgfa	platelet-derived growth factor alpha polypeptide	0.017
Igf2	insulin-like growth factor 2	0.017
Cdk2	cyclin dependent kinase 2	0.017
Pdgfb	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.017
Igfbp5	insulin-like growth factor binding protein 5	0.017
Slc39a14	solute carrier family 39 (zinc transporter), member 14	0.016
Tceb3	transcription elongation factor B (SIII), polypeptide 3	0.016
Myo1c	myosin IC	0.016
Unc5b	unc-5 homolog B (C. elegans)	0.016
Ebf1	early B-cell factor 1	0.016
Foxp1	forkhead box P1	0.016
Magt1	magnesium transporter 1	0.016
Dlgap4	discs, large homolog-associated protein 4 (Drosophila)	0.016
Smo	smoothened homolog (Drosophila)	0.016
Ddn	dendrin	0.016
Rya3	antimicrobial peptide RYA3	0.016
Arfip1	ADP-ribosylation factor interacting protein 1	0.016
RGD1308759	similar to KIAA0892 protein	0.016
Tgfb2	transforming growth factor, beta 2	0.015
Ptpn1	protein tyrosine phosphatase, non-receptor type 1	0.015
Lbr	lamin B receptor	0.015
Rassf9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	0.015
Golph3	golgi phosphoprotein 3 (coat-protein)	0.015
Rhbdl1	rhomboid, veinlet-like 1 (Drosophila)	0.015
Elf1	E74-like factor 1	0.015
RGD1310351	similar to RIKEN cDNA 4732418C07	0.015
Galnt7	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)	0.015
Stap2	signal transducing adaptor family member 2	0.015
Klk1	kallikrein 1	0.015
Pmfbp1	polyamine modulated factor 1 binding protein 1	0.015
Acaca	acetyl-coenzyme A carboxylase alpha	0.015
Pcsk7	proprotein convertase subtilisin/kexin type 7	0.015
Sfrp1	secreted frizzled-related protein 1	0.014
Itgb4	integrin, beta 4	0.014
Grasp	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein	0.014
Foxj1	forkhead box J1	0.014
Tnks1bp1	tankyrase 1 binding protein 1	0.014
Soat1	sterol O-acyltransferase 1	0.014
Ripk1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.014
Ptprf	protein tyrosine phosphatase, receptor type, F	0.014
Rarb	retinoic acid receptor, beta	0.014
Rarg	retinoic acid receptor, gamma	0.014
RGD1563136	similar to Cystatin-related protein 2 precursor (Prostatic 22 kDa glycoprotein P22K15)	0.014
Pdha2	pyruvate dehydrogenase (lipoamide) alpha 2	0.014
Golga1	golgi autoantigen, golgin subfamily a, 1	0.014
Agrn	agrin	0.014
Dlgap2	discs, large (Drosophila) homolog-associated protein 2	0.014
Nkd1	naked cuticle homolog 1 (Drosophila)	0.014
Ppp4r1	protein phosphatase 4, regulatory subunit 1	0.014
Ece1	endothelin converting enzyme 1	0.014
Lphn2	latrophilin 2	0.014
Srrm1	serine/arginine repetitive matrix 1	0.014
Inpp1	inositol polyphosphate-1-phosphatase	0.014
Dlgap3	discs, large (Drosophila) homolog-associated protein 3	0.014
Reg3a	regenerating islet-derived 3 alpha	0.013
Fndc3b	fibronectin type III domain containing 3B	0.013
Ctnnb1	catenin (cadherin associated protein), beta 1	0.013	Mouse
Tnfrsf1a	tumor necrosis factor receptor superfamily, member 1a	0.013
Gdf11	growth differentiation factor 11	0.013
Cast	calpastatin	0.013
Mmp2	matrix metallopeptidase 2	0.013
Mfhas1	malignant fibrous histiocytoma amplified sequence 1	0.013
Megf10	multiple EGF-like domains 10	0.013
Cd2	Cd2 molecule	0.013
Tpcr12	putative olfactory receptor	0.013
Eif2c2	eukaryotic translation initiation factor 2C, 2	0.013
Fgf16	fibroblast growth factor 16	0.013
Myo10	myosin X	0.013
Clca1	chloride channel accessory 1	0.013
Tal1	T-cell acute lymphocytic leukemia 1	0.013
Ralgds	ral guanine nucleotide dissociation stimulator	0.013
Lima1	LIM domain and actin binding 1	0.013
Nod1	nucleotide-binding oligomerization domain containing 1	0.013
Dlg4	discs, large homolog 4 (Drosophila)	0.013
Dnahc6	dynein, axonemal, heavy chain 6	0.013
Casp7	caspase 7	0.012
Arhgap27	Rho GTPase activating protein 27	0.012
Vav2	vav 2 guanine nucleotide exchange factor	0.012
Trim25	tripartite motif-containing 25	0.012
LOC691920	similar to kinesin-like motor protein C20orf23	0.012
Col4a3	collagen, type IV, alpha 3	0.012
LOC619574	hypothetical protein LOC619574	0.012
St8sia4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.012
Arrb1	arrestin, beta 1	0.012
Irx4	iroquois homeobox 4	0.012
Rfc1	replication factor C (activator 1) 1	0.012
Gucy2g	guanylate cyclase 2G	0.012
Dctn4	dynactin 4	0.012
Camk2g	calcium/calmodulin-dependent protein kinase II gamma	0.012
Alox5	arachidonate 5-lipoxygenase	0.012
Chd2	chromodomain helicase DNA binding protein 2	0.012
Srebf1	sterol regulatory element binding transcription factor 1	0.012
Sbk1	SH3-binding domain kinase 1	0.012
Myh11	myosin, heavy chain 11, smooth muscle	0.012
Emp2	epithelial membrane protein 2	0.012
Stk39	serine/threonine kinase 39, STE20/SPS1 homolog (yeast)	0.012
Scarf1	scavenger receptor class F, member 1	0.012
Kcng1	potassium voltage-gated channel, subfamily G, member 1	0.012
S1pr2	sphingosine-1-phosphate receptor 2	0.012
Rsad2	radical S-adenosyl methionine domain containing 2	0.012
Fgr	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.012
Calcrl	calcitonin receptor-like	0.012
Furin	furin (paired basic amino acid cleaving enzyme)	0.012
Erbb2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.012
Slc7a8	solute carrier family 7 (cationic amino acid transporter, y+ system), member 8	0.012
Jak1	Janus kinase 1	0.012
Bcl2l1	Bcl2-like 1	0.011
Tbc1d2b	TBC1 domain family, member 2B	0.011
RGD1564927	similar to TGFB-induced factor 2	0.011
Olr825	olfactory receptor 825	0.011
Col18a1	collagen, type XVIII, alpha 1	0.011
Slc12a7	solute carrier family 12 (potassium/chloride transporters), member 7	0.011
Exoc4	exocyst complex component 4	0.011
Ankrd1	ankyrin repeat domain 1 (cardiac muscle)	0.011
LOC313672	kazrin	0.011
Sdc3	syndecan 3	0.011
Clcnkb	chloride channel Kb	0.011
Cd38	CD38 molecule	0.011
Dact1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	0.011
Slc44a1	solute carrier family 44, member 1	0.011
Stk38	serine/threonine kinase 38	0.011
RGD1306750	LOC362451	0.011
Lct	lactase	0.011
Rnase1	ribonuclease, RNase A family, 1 (pancreatic)	0.011
Nrg2	neuregulin 2	0.011
Lamc1	laminin, gamma 1	0.011
Nras	neuroblastoma ras oncogene	0.011
Rdh10	retinol dehydrogenase 10 (all-trans)	0.011
Six3	SIX homeobox 3	0.011
Cgnl1	cingulin-like 1	0.011
Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	0.011
Bik	BCL2-interacting killer (apoptosis-inducing)	0.011
Flnb	filamin, beta	0.011
Toe1	target of EGR1, member 1 (nuclear)	0.011
Nr5a1	nuclear receptor subfamily 5, group A, member 1	0.011
Cask	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.011
Dnah2	dynein, axonemal, heavy chain 2	0.011
Csk	c-src tyrosine kinase	0.011
Whsc1l1	Wolf-Hirschhorn syndrome candidate 1-like 1 (human)	0.011
Mavs	mitochondrial antiviral signaling protein	0.011
Lrp5	low density lipoprotein receptor-related protein 5	0.011
Lama5	laminin, alpha 5	0.011
Sctr	secretin receptor	0.011
Il1r1	interleukin 1 receptor, type I	0.011
Arhgef12	Rho guanine nucleotide exchange factor (GEF) 12	0.011
Ehf	ets homologous factor	0.011
Cpne3	copine III	0.011
RGD1305793	similar to hypothetical protein FLJ20154	0.011
Zbtb10	zinc finger and BTB domain containing 10	0.011
Znf503	zinc finger protein 503	0.011
Pdgfrb	platelet derived growth factor receptor, beta polypeptide	0.010
Khsrp	KH-type splicing regulatory protein	0.010
Kcns3	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3	0.010
Lrrfip1	leucine rich repeat (in FLII) interacting protein 1	0.010
Sdk2	sidekick homolog 2 (chicken)	0.010
Prph2	peripherin 2	0.010
Inadl2	InaD-like 2 (Drosophila)	0.010
Nfic	nuclear factor I/C	0.010
Clca4	chloride channel accessory 4	0.010
Tor1aip2	torsin A interacting protein 2	0.010
Pou5f2	POU domain class 5, transcription factor 2	0.010
Prl3d1	Prolactin family 3, subfamily d, member 1	0.010
Ptprt	protein tyrosine phosphatase, receptor type, T	0.010
Dock1	dedicator of cyto-kinesis 1	0.010
Syde1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.010
Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	0.010
Ager	advanced glycosylation end product-specific receptor	0.010
Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	0.010
Clec11a	C-type lectin domain family 11, member a	0.010
Fabp6	fatty acid binding protein 6, ileal	0.010
Cited1	Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1	0.010
Umod	uromodulin	0.010
Fbxl7	F-box and leucine-rich repeat protein 7	0.010
Slc22a23	solute carrier family 22, member 23	0.010